Published in Mol Gen Genet on January 01, 1985
Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X chromosome. Genetics (1989) 2.99
Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev (1993) 1.71
Localization of an alpha-amanitin resistance mutation in the gene encoding the largest subunit of mouse RNA polymerase II. Mol Cell Biol (1987) 1.50
The RNA polymerase II 15-kilodalton subunit is essential for viability in Drosophila melanogaster. Mol Cell Biol (1992) 1.39
Antagonistic interactions between alleles of the RpII215 locus in Drosophila melanogaster. Genetics (1988) 0.96
Mutations in the second-largest subunit of Drosophila RNA polymerase II interact with Ubx. Genetics (1992) 0.92
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (1993) 58.26
The induction of gene activity in drosophilia by heat shock. Cell (1979) 15.17
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science (2000) 6.44
A functional genomic analysis of cell morphology using RNA interference. J Biol (2003) 5.99
The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics (1996) 5.72
Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature (2000) 4.80
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev (1998) 4.51
Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics (1992) 4.18
Ectopic expression in Drosophila. Methods Cell Biol (1994) 3.50
Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J (1995) 3.40
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature (1998) 3.34
Autosomal P[ovoD1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras. Development (1993) 3.19
X-linked female-sterile loci in Drosophila melanogaster. Genetics (1986) 2.94
Clonal analysis of the tissue specificity of recessive female-sterile mutations of Drosophila melanogaster using a dominant female-sterile mutation Fs(1)K1237. Dev Biol (1983) 2.91
Ecdysone-stimulated RNA synthesis in imaginal discs of Drosophila melanogaster. Assay by in situ hybridization. Chromosoma (1976) 2.89
wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell (1992) 2.85
Components of wingless signalling in Drosophila. Nature (1994) 2.84
The use of promoter fusions in Drosophila genetics: isolation of mutations affecting the heat shock response. Cell (1984) 2.71
The effects of zygotic lethal mutations on female germ-line functions in Drosophila. Dev Biol (1984) 2.70
corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso. Cell (1992) 2.69
Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs. Cell (1996) 2.69
The ovo locus is required for sex-specific germ line maintenance in Drosophila. Genes Dev (1987) 2.63
Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature (1999) 2.53
The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes Dev (1994) 2.50
Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway. Genes Dev (1998) 2.47
Multiple functions of Drosophila heat shock transcription factor in vivo. EMBO J (1997) 2.43
Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science (1996) 2.31
Activation of posterior gap gene expression in the Drosophila blastoderm. Nature (1995) 2.30
dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature (1994) 2.29
Towards automated cellular image segmentation for RNAi genome-wide screening. Med Image Comput Comput Assist Interv (2005) 2.19
Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila. Genes Dev (1994) 2.14
DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes Dev (1998) 2.14
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J (1993) 2.12
Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature (2001) 2.11
The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development. Nature (1990) 2.05
Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3. Nature (1990) 2.01
Simple and efficient generation of marked clones in Drosophila. Curr Biol (1993) 2.00
Genetic interactions of modifier genes and modifiable alleles in Drosophila melanogaster. Genetics (1988) 1.99
Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development (2001) 1.96
Multiple functions of segment polarity genes in Drosophila. Dev Biol (1987) 1.94
Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. Dev Biol (1994) 1.89
The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes Dev (1996) 1.87
Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development (1999) 1.86
Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Mol Cell (1999) 1.84
The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz. Nature (1997) 1.82
Identifying loci required for follicular patterning using directed mosaics. Development (1998) 1.81
An RNA polymerase II mutation in Drosophila melanogaster that mimics ultrabithorax. Chromosoma (1981) 1.74
The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes Dev (1992) 1.68
Spatial control of the actin cytoskeleton in Drosophila epithelial cells. Nat Cell Biol (2001) 1.67
Collective nomenclature for LAP proteins. Nat Cell Biol (2000) 1.64
Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes Dev (1997) 1.64
Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. Genes Dev (1994) 1.62
Genetic evidence that the sans fille locus is involved in Drosophila sex determination. Genetics (1988) 1.62
The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures. Genes Dev (1990) 1.61
Requirement of the Drosophila raf homologue for torso function. Nature (1989) 1.60
Frizzled signaling and the developmental control of cell polarity. Trends Genet (1998) 1.60
A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. Proc Natl Acad Sci U S A (1997) 1.59
The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development (1997) 1.59
Stress signaling in Drosophila. Oncogene (1999) 1.56
The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis. Cell (1999) 1.50
The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway. Cell (1995) 1.49
I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila. Genetics (1999) 1.49
Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events. Nat Cell Biol (2001) 1.46
Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development (1995) 1.43
Altering the insertional specificity of a Drosophila transposable element. Proc Natl Acad Sci U S A (1992) 1.43
Multiple roles for four-jointed in planar polarity and limb patterning. Dev Biol (2000) 1.41
The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification. Curr Biol (1999) 1.40
The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family. Eur J Biochem (2000) 1.40
Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling. Bioessays (1994) 1.39
Developmental genetics of the 2C-D region of the Drosophila X chromosome. Genetics (1985) 1.39
Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2. Mech Dev (1996) 1.39
The RNA polymerase II 15-kilodalton subunit is essential for viability in Drosophila melanogaster. Mol Cell Biol (1992) 1.39
Dual functions of wingless in the Drosophila leg imaginal disc. Development (1995) 1.38
l(1)hopscotch, A larval-pupal zygotic lethal with a specific maternal effect on segmentation in Drosophila. Dev Biol (1986) 1.37
Induction and regulation of chloroplast replication in mature tobacco leaf tissue. Plant Physiol (1972) 1.36
The torso pathway in Drosophila: lessons on receptor tyrosine kinase signaling and pattern formation. Dev Biol (1994) 1.36
Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase. Development (1993) 1.34
Small heat shock proteins of Drosophila associate with the cytoskeleton. Proc Natl Acad Sci U S A (1986) 1.34
polyhomeotic: a gene required for the embryonic development of axon pathways in the central nervous system of Drosophila. Genes Dev (1988) 1.34
Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila. Genes Dev (1993) 1.32
Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis. Genes Dev (1997) 1.31
The roles of the Drosophila JAK/STAT pathway. Oncogene (2000) 1.31
The effect of heat shock on RNA synthesis in Drosophila tissues. Cell (1976) 1.31
The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Dev Biol (1996) 1.29
Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling. Genes Dev (1999) 1.29
The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis. Development (1996) 1.25
A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. Curr Biol (2000) 1.24
wingless refines its own expression domain on the Drosophila wing margin. Nature (1996) 1.24
A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. Mol Cell Biol (1995) 1.21
The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS. Dev Biol (1996) 1.20
Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway. Mol Cell (1998) 1.19
A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogaster. Dev Biol (1985) 1.18
Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila. Curr Opin Cell Biol (2000) 1.17
Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK. Genes Dev (1996) 1.17
The crooked neck gene of Drosophila contains a motif found in a family of yeast cell cycle genes. Genes Dev (1991) 1.16
Genetic analysis of chromosomal region 67A-D of Drosophila melanogaster. Genetics (1988) 1.15
Developmental genetics of the 2E-F region of the Drosophila X chromosome: a region rich in "developmentally important" genes. Genetics (1984) 1.14
A temporal switch in DER signaling controls the specification and differentiation of veins and interveins in the Drosophila wing. Development (1999) 1.14
Drosophila melanogaster homologs of the raf oncogene. Mol Cell Biol (1987) 1.12