Stimulation of Rauscher leukemia virus DNA polymerase DNA-directed DNA synthesis by cationic trypanocides and polyamines.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 3965127)

Published in Cancer Res on January 01, 1985

Authors

S L Marcus, D P Petrylak, J J Burchenal, C J Bacchi

Articles by these authors

(truncated to the top 100)

Eligibility and response guidelines for phase II clinical trials in androgen-independent prostate cancer: recommendations from the Prostate-Specific Antigen Working Group. J Clin Oncol (1999) 9.22

Polyamine metabolism: a potential therapeutic target in trypanosomes. Science (1980) 2.41

Structural and biochemical characterization of the type III secretion chaperones CesT and SigE. Nat Struct Biol (2001) 2.04

In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei. Mol Biochem Parasitol (1987) 1.97

SifA permits survival and replication of Salmonella typhimurium in murine macrophages. Cell Microbiol (2001) 1.88

Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylase. Antimicrob Agents Chemother (1990) 1.74

In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei. Mol Biochem Parasitol (1983) 1.69

Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. Proc Natl Acad Sci U S A (1992) 1.68

A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer. J Transl Med (2006) 1.66

Activation of Akt/protein kinase B in epithelial cells by the Salmonella typhimurium effector sigD. J Biol Chem (2000) 1.61

Disseminated strongyloidiasis with central nervous system involvement diagnosed antemortem in a patient with acquired immunodeficiency syndrome and Burkitts lymphoma. Cancer (1990) 1.59

Expression of cardiac cytokines and inducible form of nitric oxide synthase (NOS2) in Trypanosoma cruzi-infected mice. J Mol Cell Cardiol (1999) 1.49

Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells. Infect Immun (1999) 1.48

Photodynamic therapy. Eur J Cancer (1992) 1.44

Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7. Infect Immun (1999) 1.42

Identification of the messenger RNAs coding for the gag and env gene products of the murine mammary tumor virus. Proc Natl Acad Sci U S A (1979) 1.42

Methionine recycling pathways and antimalarial drug design. Antimicrob Agents Chemother (1995) 1.40

The relative hydrophobicity of oncornaviral structural proteins. Virology (1978) 1.38

Catalytic irreversible inhibition of Trypanosoma brucei brucei ornithine decarboxylase by substrate and product analogs and their effects on murine trypanosomiasis. Biochem Pharmacol (1985) 1.32

Purification and properties of Rauscher leukemia virus DNA polymerase and selective inhibition of mammalian viral reverse transcriptase by inorganic phosphate. J Biol Chem (1977) 1.28

Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): mechanisms and clinical results. J Clin Laser Med Surg (1996) 1.28

Purification of avian myeloblastosis virus DNA polymerase by affinity chromatography on polycytidylate-agarose. J Virol (1974) 1.27

Purification and properties of murine mammary tumor virus DNA polymerase. Virology (1976) 1.20

Effect of DL-alpha-difluoromethylornithine on methionine cycle intermediates in Trypanosoma brucei brucei. Mol Biochem Parasitol (1988) 1.19

Rapid in vivo monitoring of chemotherapeutic response using weighted sodium magnetic resonance imaging. Clin Cancer Res (2000) 1.18

Inducible resistance to oxidant stress in the protozoan Leishmania chagasi. J Biol Chem (2000) 1.15

Effects of the ornithine decarboxylase inhibitors DL-alpha-difluoromethylornithine and alpha-monofluoromethyldehydroornithine methyl ester alone and in combination with suramin against Trypanosoma brucei brucei central nervous system models. Am J Trop Med Hyg (1987) 1.10

Photodynamic therapy for dysplastic Barrett's oesophagus: a prospective, double blind, randomised, placebo controlled trial. Gut (2000) 1.10

New drug combination for experimental late-stage African trypanosomiasis: DL-alpha-difluoromethylornithine (DFMO) with suramin. Am J Trop Med Hyg (1984) 1.06

Which patients with newly diagnosed prostate cancer need a radionuclide bone scan? An analysis based on 631 patients. Int J Radiat Oncol Biol Phys (2000) 1.04

Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling. J Biol Chem (1993) 1.03

Observations on template-specific conditions for DNA synthesis by avian myeloblastosis virus DNA polymerase. Nucleic Acids Res (1976) 1.02

Quantitative of murine mammary tumor virus-related RNA in mammary tissues of low- and high-mammary-tumor-incidence mouse strains. J Virol (1981) 1.02

Content, synthesis, and function of polyamines in trypanosomatids: relationship to chemotherapy. J Protozool (1981) 1.02

Polyamine depletion following exposure to DL-alpha-difluoromethylornithine both in vivo and in vitro initiates morphological alterations and mitochondrial activation in a monomorphic strain of Trypanosoma brucei brucei. J Protozool (1986) 1.01

Phase II study of eribulin mesylate (E7389) in patients with metastatic castration-resistant prostate cancer stratified by prior taxane therapy. Ann Oncol (2011) 1.00

Evidence for allosterism in in vitro DNA synthesis on RNA templates. Proc Natl Acad Sci U S A (1974) 0.99

Novel alkylpolyamine analogues that possess both antitrypanosomal and antimicrosporidial activity. Bioorg Med Chem Lett (2001) 0.99

Substrate specificities of 5'-deoxy-5'-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells. Mol Biochem Parasitol (1988) 0.98

Characterization of protein-DNA interactions within the peroxisome proliferator-responsive element of the rat hydratase-dehydrogenase gene. J Biol Chem (1993) 0.98

In vitro trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors. Antimicrob Agents Chemother (1996) 0.98

The effect of magnesium and manganese ions on the structure and template activity for reverse transcriptase of polyribocytidylate and its 2'-0-methyl derivative. Nucleic Acids Res (1977) 0.97

Simultaneous purification of murine mammary tumor virus structural proteins: analysis of antigenic reactivities of native gp34 by radioimmunocompetition assays. J Virol (1979) 0.96

Uptake of alpha-difluoromethylornithine by Trypanosoma brucei brucei. Biochem Pharmacol (1986) 0.96

Effects of intermediates of methionine metabolism and nucleoside analogs on S-adenosylmethionine transport by Trypanosoma brucei brucei and a drug-resistant Trypanosoma brucei rhodesiense. Biochem Pharmacol (1998) 0.96

Differential sensitivity of Trypanosoma brucei rhodesiense isolates to in vitro lysis by arsenicals. Exp Parasitol (1991) 0.96

Antagonism by polyamines of the curative effects of alpha-difluoromethylornithine in Trypanosoma brucei brucei infections. Biochem Pharmacol (1981) 0.95

Resolution and characterization of intracytoplasmic forms of reverse transcriptase from Rauscher leukemia virus-producing cells. J Virol (1978) 0.94

Evidence for template-specific sites in DNA polymerases. Biochem Biophys Res Commun (1974) 0.94

Dexamethasone does not significantly contribute to the response rate of docetaxel and estramustine in androgen independent prostate cancer. J Urol (2000) 0.93

Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents. Bioorg Med Chem Lett (2001) 0.93

Further studies on difluoromethylornithine in African trypanosomes. Med Biol (1981) 0.92

Protein methylases in Trypanosoma brucei brucei: activities and response to DL-alpha-difluoromethylornithine. J Gen Microbiol (1991) 0.92

A unique transporter of S-adenosylmethionine in African trypanosomes. FASEB J (1997) 0.92

Transactivation of the peroxisome proliferator-activated receptor is differentially modulated by hepatocyte nuclear factor-4. Gene Expr (1994) 0.92

Subcellular localization of the enzymes of the arginine dihydrolase pathway in Trichomonas vaginalis and Tritrichomonas foetus. J Eukaryot Microbiol (1995) 0.92

S-(5'-deoxy-5'-adenosyl)-1-aminoxy-4-(methylsulfonio)-2-cyclopentene (AdoMao): an irreversible inhibitor of S-adenosylmethionine decarboxylase with potent in vitro antitrypanosomal activity. J Med Chem (1995) 0.92

Dense Crithidia growth and heme sparing: relation to Fe, Cu, Mo chelation. J Protozool (1978) 0.90

Southwest Oncology Group Study of paclitaxel and carboplatin for advanced transitional-cell carcinoma: the importance of survival as a clinical trial end point. J Clin Oncol (2000) 0.90

Specific inhibition of DNA polymerase-associated RNase H by DNA. J Virol (1977) 0.90

Biopterin content of human and rat fluids and tissues determined protozoologically. Am J Clin Nutr (1974) 0.90

S-adenosylmethionine synthetase in bloodstream Trypanosoma brucei. Biochim Biophys Acta (1993) 0.88

Terminal deoxyribonucleotidyl transferase activity in acute undifferentiated leukemia. Biochem Biophys Res Commun (1976) 0.88

Parasite polyamine metabolism: targets for chemotherapy. Biochem Soc Trans (1994) 0.88

Inhibition by several standard antiprotozoal drugs of growth and O2 uptake of cells and particulate preparations of a Leptomonas. J Protozool (1974) 0.88

Phosphoproteins of the murine mammary tumor virus. Virology (1978) 0.88

Inhibition of polyamine biosynthesis by alpha-difluoromethylornithine in African trypanosomes and Pneumocystis carinii as a basis of chemotherapy: biochemical and clinical aspects. Am J Trop Med Hyg (1986) 0.87

Synthesis and antitrypanosomal activities of a series of 7-deaza-5'-noraristeromycin derivatives with variations in the cyclopentyl ring substituents. Antimicrob Agents Chemother (1997) 0.86

Trichomonas vaginalis: characterization of ornithine decarboxylase. Biochem J (1993) 0.86

Drug-resistant Leptomonas: cross-resistance in trypanocide-resistant clones. Antimicrob Agents Chemother (1975) 0.86

Effects of some antitumor agents on growth and glycolytic enzymes of the flagellate Crithidia. J Bacteriol (1969) 0.85

Antitrypanosomal activity of purine nucleosides can be enhanced by their conversion to O-acetylated derivatives. Antimicrob Agents Chemother (1996) 0.85

Retroviral "terminal deoxynucleotidyl transferase" activity is reverse transcription. Virology (1978) 0.85

Polyamines in trypanosomatids. J Bacteriol (1977) 0.84

(+)-7-Deaza-5'-noraristeromycin as an anti-trypanosomal agent. J Med Chem (1997) 0.84

Bleomycin-induced life prolongation of mice infected with Trypanosoma brucei brucei EATRO 110. Trans R Soc Trop Med Hyg (1981) 0.84

Efficacy of combinations of difluoromethylornithine and bleomycin in a mouse model of central nervous system African trypanosomiasis. Proc Natl Acad Sci U S A (1983) 0.84

The effect of cystectomy, and perioperative methotrexate, vinblastine, doxorubicin and cisplatin chemotherapy on the risk and pattern of relapse in patients with muscle invasive bladder cancer. J Urol (2000) 0.84

O2-polarographic studies on soluble and mitochondrial enzymes of Crithidia fasciculata; glycerophosphage enzymes. J Protozool (1968) 0.83

Polyamine derivatives as inhibitors of trypanothione reductase and assessment of their trypanocidal activities. Bioorg Med Chem (1997) 0.83

The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo. Gene (1994) 0.83

The Monitoring of ALA-Induced Protoporphyrin IX Accumulation and Clearance in Patients with Skin Lesions by In Vivo Surface-Detected Fluorescence Spectroscopy. Lasers Med Sci (1999) 0.83

Which patients with newly diagnosed prostate cancer need a computed tomography scan of the abdomen and pelvis? An analysis based on 588 patients. Urology (1999) 0.82

Effect of DL-alpha-difluoromethylornithine on polyamine synthesis and interconversion in Trichomonas vaginalis grown in a semi-defined medium. Mol Biochem Parasitol (1988) 0.82

Synthesis and content of polyamines in bloodstream Trypanosma brucei. J Protozool (1979) 0.82

Antitumor phthalanilides active in acute and chronic Trypanosoma brucei brucei murine infections. Am J Trop Med Hyg (1984) 0.82

Reverse transcriptase-associated RNase H activity. II. Inhibition by natural and synthetic RNA. J Virol (1978) 0.82

N-terminal conservation of putative type III secreted effectors of Salmonella typhimurium. Mol Microbiol (2000) 0.82

The p56(lck)-interacting protein p62 stimulates transcription via the SV40 enhancer. J Biol Chem (1999) 0.82

Monoclonal antibodies and radioimmunoconjugates in the diagnosis and treatment of prostate cancer. Semin Urol (1992) 0.82

Effect of nicotine on the motility of the oviducts in the rhesus monkey: a preliminary report. J Reprod Fertil (1972) 0.82

Template-specific requirements for DNA synthesis by the Mason-Pfizer monkey virus DNA polymerase: unique aspects. Biochim Biophys Acta (1978) 0.82

DNA complementary to rabbit globin mRNA made by E. coli polymerase I. Biochem Biophys Res Commun (1973) 0.82

Functional activity of the corpus luteum following hysterectomy. J Clin Endocrinol Metab (1970) 0.81

Ornithine decarboxylase in Trypanosoma brucei brucei: evidence for selective toxicity of difluoromethylornithine. J Protozool (1982) 0.81

Synthesis and anti-trypanosomal activity of various 8-aza-7-deaza-5'noraristeromycin derivatives. J Med Chem (1997) 0.81

Therapeutic strategies for localized prostate cancer. Rev Urol (2001) 0.81

Inhibition of Trichomonas vaginalis ornithine decarboxylase by amino acid analogs. Biochem Pharmacol (1992) 0.81

Effect of an intrauterine contraceptive device on uterine motility in the rat. Obstet Gynecol (1966) 0.81

Synthesis of DNA complementary to AMV RNA using E. coli polymerase I. Biochem Biophys Res Commun (1974) 0.80