Published in Immunology on December 01, 1970
Interaction of aggregated -globulin with B lymphocytes. J Exp Med (1972) 9.29
The Raji cell radioimmune assay for detecting immune complexes in human sera. J Clin Invest (1976) 8.06
Circulating and intra-articular immune complexes in patients with rheumatoid arthritis. Correlation of 125I-Clq binding activity with clinical and biological features of the disease. J Clin Invest (1976) 5.96
Circulating immune complexes in the serum in systemic lupus erythematosus and in carriers of hepatitis B antigen. Quantitation by binding to radiolabeled C1q. J Clin Invest (1974) 5.81
Routine assay for the detection of immune complexes of known immunoglobulin class using solid phase C1q. Clin Exp Immunol (1976) 4.97
Antibodies to polynucleotides in human sera: antigenic specificity and relation to disease. J Exp Med (1971) 4.62
C1q deviation test for the detection of immune complexes, aggregates of IgG, and bacterial products in human serum. J Exp Med (1975) 3.21
Mannan antigenemia in the diagnosis of invasive Candida infections. J Clin Invest (1976) 2.69
Binding of soluble immune complexes to human lymphoblastoid cells. II. Use of Raji cells to detect circulating immune complexes in animal and human sera. J Exp Med (1974) 2.51
Complement-mediated inhibition of immune precipitation. I. Role of the classical and alternative pathways. Clin Exp Immunol (1982) 2.20
Polynucleotide immune complexes in serum and glomeruli of patients with systemic lupus erythematosus. Am J Pathol (1974) 2.12
Detection of circulating antigen-antibody complexes by their inhibitory effect on the agglutination of IgG-coated particles by rheumatioid factor of Clq. Clin Exp Immunol (1976) 2.00
Circulating complement breakdown products in patients with rheumatoid arthritis. Correlation between plasma C3d, circulating immune complexes, and clinical activity. J Clin Invest (1977) 1.97
Detection of immune complexes. The use of radioimmunoassays with Clq and monoclonal rheumatoid factor. J Clin Invest (1977) 1.96
Age-dependent production of IgA and IgM autoantibodies against IgG2a in a colony of 129/Sv mice. J Exp Med (1979) 1.94
Studies of serum complement in the hypocomplementaemic nephritides. Clin Exp Immunol (1974) 1.67
Immune complexes and complement hypercatabolism in patients with leprosy. Clin Exp Immunol (1976) 1.66
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. Arthritis Res Ther (2008) 1.62
Application of the solid phase C1q and Raji cell radioimmune assays for the detection of circulating immune complexes in glomerulonephritis. J Clin Invest (1978) 1.50
Interactions of C-reactive protein with the complement system. III. Complement-dependent passive hemolysis initiated by CRP. J Exp Med (1975) 1.48
Circulating immune complexes in retinal vasculitis. Clin Exp Immunol (1977) 1.30
Presence of C1q-reactive immune complexes in patients with leprosy. Clin Exp Immunol (1972) 1.28
Complement metabolism in the seronegative arthritides. Ann Rheum Dis (1974) 1.28
Isolation of circulating immune complexes using Raji cells. Separation of antigens from immune complexes and production of antiserum. J Clin Invest (1978) 1.28
Circulating immune complexes in serum from patients with dengue haemorrhagic fever. Clin Exp Immunol (1979) 1.27
Detection of circulating IgG aggregates and immune complexes using 125I protein A from Staphylococcus aureus. Ann Rheum Dis (1976) 1.25
Intrahepatic expression of serum hepatitis virus-associated antigens. J Exp Med (1971) 1.22
Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FcgammaRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE. Ann Rheum Dis (2003) 1.20
Antiglobulins and glomerulonephritis. Classification of patients by the reactivity of their sera and renal tissue with aggregated and native human IgG. J Clin Invest (1975) 1.20
Circulating immune complexes detected by 125I-Clq deviation test in sera of cancer patients. J Clin Invest (1977) 1.19
Relationship between anti-DNA antibodies complement consumption and circulating immune complexes in systemic lupus erythematosus. Clin Exp Immunol (1977) 1.18
Absence of the eighth component of complement in association with systemic lupus erythematosus-like disease. J Clin Invest (1977) 1.18
Binding of soluble immune complexes to Raji lymphocytes. Role of receptors for complement components, C1q and C3-C3b. Immunology (1978) 1.18
Pathology, pathogenesis, and aetiology of rheumatoid arthritis. Ann Rheum Dis (1972) 1.15
Immune complexes of hepatitis B surface antigen in the pathogenesis of periarteritis nodosa. A study of seven necropsy cases. Am J Pathol (1978) 1.15
Immune complex detection and complement activity in rheumatoid arthritis: a comparative study of a radioimmunoassay using monoclonal rheumatoid factor, gel diffusion techniques and C4 activity. Clin Exp Immunol (1978) 1.12
Changes in intra-vascular complement and anti-treponemal antibody titres preceding the Jarisch-Herxheimer reaction in secondary syphilis. Clin Exp Immunol (1976) 1.12
Immune complexes in early arthritis. II. Immune complex constituents are synthesized in the synovium before rheumatoid factors. Clin Exp Immunol (1982) 1.07
The occurrence of circulating immune complexes and viral antigens in idiopathic thrombocytopenic purpura. Clin Exp Immunol (1977) 1.07
Circulating immune complexes in systemic lupus erythematosus. Clin Exp Immunol (1977) 1.07
Immune complexes in human diseases: a review. Am J Pathol (1980) 1.05
Ability of complement to release systemic lupus erythematosus immune complexes from cell receptors. Clin Exp Immunol (1981) 1.05
Circulating immune complexes in ulcerative colitis. I. Correlation to disease activity. Clin Exp Immunol (1978) 1.04
Self-induced glomerulonephritis. Br Med J (1974) 1.04
A DNA-binding protein in the serum of certain mammalian species. Proc Natl Acad Sci U S A (1972) 1.03
The binding of myelin basic protein to the Fc region of aggregated IgG and to immune complexes. Clin Exp Immunol (1980) 1.02
Circulating immune complexes in cutaneous vasculitis. Detection with C1q and monoclonal rheumatoid factor. J Clin Invest (1979) 1.01
Interpretation of the Raji cell assay in sera containing anti-nuclear antibodies and immune complexes. Clin Exp Immunol (1981) 0.98
Circulating immune complexes and disease activity in Crohn's disease. Gut (1978) 0.97
Detection and characterization of DNA-anti-DNA complexes in a patient with systemic lupus erythematosus. Clin Exp Immunol (1977) 0.97
Familial C1q deficiency associated with renal and cutaneous disease. Clin Exp Immunol (1981) 0.97
C1q binding substances in pemphigus and bullous pemphigoid. Detection with a [131I] C1q binding assay. Clin Exp Immunol (1977) 0.96
Serum heat-labile opsonins in systemic lupus erythematosus. J Clin Invest (1974) 0.95
Detection of circulating anticomplementary factors in chronic lung diseases. Clin Exp Immunol (1978) 0.92
Mixed connective tissue disease. West J Med (1980) 0.92
Inhibition of polymorphonuclear leukocyte chemiluminescence for detection of immune complexes in human sera. J Clin Invest (1980) 0.92
Measles infection. Involvement of the complement system. Clin Exp Immunol (1976) 0.91
Circulating complexes in leprosy studied by the platelet aggregation test. The platelet aggregation test and its relation to the Rubino test and other sero-immunological parameters in 135 patients with leprosy. Clin Exp Immunol (1978) 0.91
Inactivation of C1 in rheumatoid synovial fluid, purfied C1 and C1 esterase, by gold compounds. Clin Exp Immunol (1974) 0.91
Circulating immune complexes in experimental filariasis. Clin Exp Immunol (1980) 0.90
'In vitro' study of a reaction between the complement system and cellular DNA. Immunology (1978) 0.90
Isolation of circulating immune complexes by conglutinin and separation of antigen from dissociated complexes by immobilized protein A. Clin Exp Immunol (1981) 0.88
Precipitation of 125I-labelled IgG aggregates by factors in sera of healthy individuals and of patients with rheumatoid arthritis. Ann Rheum Dis (1977) 0.85
Quantitation of circulating immune complexes in serum by Raji cells using an enzyme-linked immunosorbent assay. Clin Exp Immunol (1980) 0.85
Complement-fixing material in ther sera of patients with rheumatoid arthritis. Clin Exp Immunol (1978) 0.83
Pathogenetic mechanisms in dengue haemorrhagic fever: report of an international collaborative study. Bull World Health Organ (1973) 0.83
Henry G. Kunkel 1916-1983. An appreciation of the man and his scientific contributions & a bibliography of his research papers. J Exp Med (1985) 0.82
Purification of the subunit Clq from the first component of equine complement. Immunology (1979) 0.81
Circulating immune complexes after repeated halothane anaesthesia. Br Med J (1977) 0.81
Cellular immunity in experimental glomerulonephritis of rats. II. A sequential study of immunological events occurring during development of the disease. Immunology (1973) 0.81
MRL mice show an age-related impairment of IgG aggregate removal from the circulation. Clin Exp Immunol (1985) 0.81
C1q protein binds to the apoptotic nucleolus and causes C1 protease degradation of nucleolar proteins. J Biol Chem (2015) 0.81
Immunochemical quantitation of complement components of Clq and C3 in sera and synovial fluids of patients with bone and joint diseases. Ann Rheum Dis (1980) 0.81
Fast liver catabolism of C1q in patients with paraproteinaemia and depletion of the classical pathway of complement. Clin Exp Immunol (1987) 0.80
Studies of the action of some anti-inflammatory drugs on complement mediated immune haemolysis. Br J Clin Pharmacol (1975) 0.80
Complement activating cryoglobulins in the nephritis of systemic lupus erythematosus. Clin Exp Immunol (1984) 0.80
A complete selective C1q deficiency in a patient with discoid lupus erythematosus (DLE). Clin Exp Immunol (1982) 0.79
Rat spleen leucocyte (RSL) radioimmunoassay for the detection and quantification of soluble immune complexes. Clin Exp Immunol (1978) 0.78
Immunofluorescent investigations in cutaneous vasculitis. I. Histotopical demonstration of complement/complement factors. Arch Dermatol Res (1975) 0.78
Sequential determination of circulating immune complexes in experimental filariasis. Infect Immun (1981) 0.78
Inhibition of antibody-dependent cellular cytotoxicity by artificial immune complexes and pathological sera. Immunology (1979) 0.77
Similarities and dissimilarities between the binding ability of C1q and collagen. Clin Exp Immunol (1981) 0.76
Three step purification of C1q by DNA precipitation, ion exchange and lectin affinity chromatography. J Clin Pathol (1982) 0.76
Drosophila chromatin: an immunological study. Nucleic Acids Res (1975) 0.76
Tumour markers with unknown functions in gynaecological neoplasia. Arch Gynecol (1980) 0.75
Detection of immune complexes in human serum by precipitin reaction with clq component of complement. Calif Med (1971) 0.75
Recent advances in the immunopathogenesis of systemic lupus erythematosus. West J Med (1975) 0.75
"Immune complexes" in every cutaneous vasculitis with "immune deposits"? Arch Dermatol Res (1979) 0.75
Electrophoretic transfer blotting analysis of immune complexes in rheumatoid arthritis. Clin Exp Immunol (1986) 0.75
Characteristics of immune complexes in connective tissue diseases. Trans Am Clin Climatol Assoc (1975) 0.75
Immunological studies concerning the nephritis of systemic lupus erythematosus. J Exp Med (1967) 10.22
Isolation of a thermolabile serum protein which precipitates gamma-globulin aggregates and participates in immune hemolysis. Proc Soc Exp Biol Med (1961) 5.41
Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis. Partial characterization and relationship to lowered complement levels. Clin Exp Immunol (1970) 5.10
The effect of complements on soluble antigen-antibody complexes. J Immunol (1957) 3.21
Effect of mercaptoethanol on complement binding ability of human 7 S gammaglobulin. Proc Soc Exp Biol Med (1963) 3.15
SERUM LEVELS OF BETA-1C GLOBULIN, A COMPLEMENT COMPONENT, IN THE NEPHRITIDES, LIPOID NEPHROSIS, AND OTHER CONDITIONS. J Clin Invest (1964) 2.84
Serial complement component alterations in acute glomerulonephritis and systemic lupus erythematosus. Clin Exp Immunol (1969) 2.81
RECONSTITUTION OF 7S MOLECULES FROM L AND H POLYPEPTIDE CHAINS OF ANTIBODIES AND GAMMA-GLOBULINS. J Exp Med (1964) 2.78
The complement profile in acute glomerulonephritis systemic lupus erythematosus and hypocomplementemic chronic glomerulonephritis. Contrasts and experimental correlations. Int Arch Allergy Appl Immunol (1968) 2.38
ACTIVITY OF DISSOCIATED AND REASSOCIATED 19S ANTI-GAMMA-GLOBULINS. J Exp Med (1964) 2.29
The joint-fluid gammaG-globulin complexes and their relationship to intraarticular complement dimunition. Ann N Y Acad Sci (1969) 2.26
Aggregation of gamma-G3 proteins: relevance to the hyperviscosity syndrome. J Clin Invest (1970) 2.19
Quantitative studies of complement fixation. Bacteriol Rev (1958) 2.06
Problems encountered in double diffusion analysis in agar of hapten specific immune systems. I. Complement dependent precipitation. J Immunol (1965) 1.69
Agglutinating activity of the complement component C'1q in the F-II latex fixation test. J Immunol (1966) 1.68
Complement: heterogeneity of binding of the first component of complement as a function of antibody concentration. J Immunol (1969) 1.11
The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1982) 67.54
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum (1987) 14.21
Immunological studies concerning the nephritis of systemic lupus erythematosus. J Exp Med (1967) 10.22
Interaction of aggregated -globulin with B lymphocytes. J Exp Med (1972) 9.29
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J Clin Invest (1966) 8.64
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus. J Immunol (1966) 7.40
Individual Antigenic Specificity of Isolated Antibodies. Science (1963) 7.27
Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers. J Exp Med (1968) 5.72
QUANTITATIVE ANTISTREPTOKINASE STUDIES IN PATIENTS INFECTED WITH GROUP A HEMOLYTIC STREPTOCOCCI: A COMPARISON WITH SERUM ANTISTREPTOLYSIN AND GAMMA GLOBULIN LEVELS WITH SPECIAL REFERENCE TO THE OCCURRENCE OF RHEUMATIC FEVER. J Clin Invest (1948) 5.25
Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis. Partial characterization and relationship to lowered complement levels. Clin Exp Immunol (1970) 5.10
Recognition by pregnancy serums of non-HL-A alloantigens selectively expressed on B lymphocytes. J Exp Med (1975) 4.96
Cross-idiotypic specificity among monoclonal IgM proteins with anti- -globulin activity. J Exp Med (1973) 4.93
IgG on lymphocyte surfaces; technical problems and the significance of a third cell population. J Immunol (1975) 4.92
Antibodies to polynucleotides in human sera: antigenic specificity and relation to disease. J Exp Med (1971) 4.62
Antigenic specificities related to the cold agglutinin activity of gamma M globulins. Science (1968) 4.32
Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells. J Exp Med (1979) 3.76
Primary immunodeficiencies. Report of a World Health Organization Committee. Pediatrics (1971) 3.69
Human lymphocyte-sheep erythrocyte rosette formation: some characteristics of the interaction. Clin Immunol Immunopathol (1973) 3.55
Evidence for linkage between HL-A histocompatibility genes and those involved in the synthesis of the second component of complement. J Exp Med (1974) 3.38
Opportunistic infections and immune deficiency in homosexual men. Ann Intern Med (1982) 3.29
Human mononuclear phagocyte differentiation antigens. I. Patterns of antigenic expression on the surface of human monocytes and macrophages defined by monoclonal antibodies. J Immunol (1983) 3.26
Human immunoglobulins: classes, subclasses, genetic variants, and idiotypes. Adv Immunol (1973) 3.25
Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies. J Clin Invest (1974) 3.24
Identification of human B and T lymphocytes by scanning electron microscopy. J Exp Med (1973) 3.21
Ia-bearing T lymphocytes in man. Their identification and role in the generation of allogeneic helper activity. J Exp Med (1978) 3.18
A subclass of human gamma-A-globulins (gamma-A2) which lacks the disulfied bonds linking heavy and light chains. J Exp Med (1968) 2.98
Occurrence of surface IgM, IgD, and free light chains of human lymphocytes. J Exp Med (1974) 2.93
Hidden rheumatoid factors with specificity for native gamma globulins. Arthritis Rheum (1966) 2.87
Lymphocytes in human immunodeficiency states: a study of membrane-associated immunoglobulins. Eur J Immunol (1971) 2.86
Studies of the Vi (gamma-2c) subgroup of gamma-globulin. A relationship between concentration and genetic type among normal individuals. J Exp Med (1967) 2.82
Expression of Ia-like antigen molecules on human granulocytes during early phases of differentiation. Proc Natl Acad Sci U S A (1977) 2.80
Peripheral blood Ia-positive T cells. Increases in certain diseases and after immunization. J Exp Med (1980) 2.76
Occurrence of -globulin complexes in serum and joint fluid of rheumatoid arthritis patients: use of monoclonal rheumatoid factors as reagents for their demonstration. J Exp Med (1971) 2.75
Studies with B-cell allo- and hetero-antisera: parallel reactivity and special properties. Scand J Immunol (1976) 2.74
Autologous mixed lymphocyte culture reactions and generation of cytotoxic T cells. J Exp Med (1977) 2.66
Nature of cold-reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus. Arthritis Rheum (1975) 2.65
Systemic lupus erythematosus: prototype of immune complex nephritis in man. J Exp Med (1971) 2.64
The human Ia system. Adv Immunol (1979) 2.62
Similarities in the light chains of anti-gamma-globulins showing cross-idiotypic specificities. J Exp Med (1974) 2.60
Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays. J Exp Med (1972) 2.47
C1g precipitins in the sera of patients with systemic lupus erythematosus and other hypocomplementemic states: characterization of high and low molecular weight types. J Exp Med (1971) 2.43
Antibodies to polynucleotides: distribution in human serums. Science (1969) 2.43
The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases. J Clin Invest (1973) 2.42
Human dendritic cells: major stimulators of the autologous and allogeneic mixed leucocyte reactions. Clin Exp Immunol (1982) 2.41
Induction of in vitro differentiation and immunoglobulin synthesis of human leukemic B lymphocytes. J Exp Med (1978) 2.39
Sheep red cell binding to human lymphocytes treated with neuraminidase; enhancement of T cell binding and identification of a subpopulation of B cells. J Exp Med (1973) 2.37
Ia+ T cells in synovial fluid and tissues of patients with rheumatoid arthritis. Arthritis Rheum (1981) 2.30
Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes. J Immunol (1975) 2.28
Human T cell hybridomas secreting factors for IgA-specific help, polyclonal B cell activation, and B cell proliferation. J Exp Med (1982) 2.27
The joint-fluid gammaG-globulin complexes and their relationship to intraarticular complement dimunition. Ann N Y Acad Sci (1969) 2.26
Idiotype-like molecules on cells of a human T cell leukemia. J Exp Med (1983) 2.19
Aggregation of gamma-G3 proteins: relevance to the hyperviscosity syndrome. J Clin Invest (1970) 2.19
The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias. J Exp Med (1975) 2.13
Idiotypic specificity of surface immunoglobulin and the maturation of leukemic bone-marrow-derived lymphocytes. Proc Natl Acad Sci U S A (1974) 2.13
Polynucleotide immune complexes in serum and glomeruli of patients with systemic lupus erythematosus. Am J Pathol (1974) 2.12
Lymphocyte binding of aggregated IgG and surface Ig staining in chronic lymphocytic leukaemia. Clin Exp Immunol (1973) 2.11
Immunologic studies concerning the pulmonary lesions in Goodpasture's syndrome. Am J Pathol (1969) 2.11
Antibodies to a specific surface antigen of T cells in human sera inhibiting mixed leukocyte culture reactions. J Exp Med (1973) 2.11
Variable patterns of immunoglobulin and complement deposition in the kidneys of patients with systemic lupus erythematosus. Am J Pathol (1969) 2.11
Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts. Scand J Immunol (1983) 2.10
Evidence for a subset of rheumatoid factors that cross-react with DNA-histone and have a distinct cross-idiotype. J Exp Med (1980) 2.10
Experimental approaches tohomogenous antibody populations. iIndividual antigenic specificity, cross specificity and diversity of human antibodies. Fed Proc (1970) 2.10
Complement deficiency states. Medicine (Baltimore) (1978) 2.08
An immunofluorescent study of the skin lesions in systemic lupus erythematosus. Arthritis Rheum (1966) 2.07
Hereditary C2 deficiency with some manifestations of systemic lupus erythematosus. J Immunol (1972) 2.02
Stimulation of human B lymphocytes by antibodies to IgM and IgG: functional evidence for the expression of IgG on B-lymphocyte surface membranes. Clin Immunol Immunopathol (1980) 2.00
Induction of polyclonal antibody synthesis by human allogeneic and autologous helper factors. J Exp Med (1979) 1.98
The nature of the stimulatory cell in human allogeneic and autologous MLC reactions; role of isolated IgM-bearing B cells. J Immunol (1979) 1.96
Detection of immune complexes. The use of radioimmunoassays with Clq and monoclonal rheumatoid factor. J Clin Invest (1977) 1.96
Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis. J Immunol (1985) 1.92
Specific concentration of polynucleotide immune complexes in the cryoprecipitates of patients with systemic lupus erythematosus. J Clin Invest (1975) 1.91
Studies on DNA antibodies using DNA labelled with actinomycin-D (3H) or dimethyl (3H) sulphate. Clin Exp Immunol (1969) 1.88