Published in Proc Natl Acad Sci U S A on November 01, 1974
Ia-bearing T lymphocytes in man. Their identification and role in the generation of allogeneic helper activity. J Exp Med (1978) 3.18
Induction of in vitro differentiation and immunoglobulin synthesis of human leukemic B lymphocytes. J Exp Med (1978) 2.39
Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities. Blood (2010) 1.79
Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis. Proc Natl Acad Sci U S A (1978) 1.78
Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation. J Exp Med (1979) 1.70
Extracellular idiotypic immunoglobulin arising from human leukemic B lymphocytes. J Exp Med (1980) 1.57
Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes. J Exp Med (1976) 1.41
Malignant lymphomas--a conceptual understanding of morphologic diversity. A review. Am J Pathol (1979) 1.30
Receptors for Helix pomatia A haemagglutinin on leukaemic lymphocytes from patients with chronic lymphocytic leukaemia (CLL). Clin Exp Immunol (1976) 1.14
Induction of proliferation and differentiation of neoplastic B cells by anti-immunoglobulin and T-cell factors. Proc Natl Acad Sci U S A (1981) 1.12
In vitro idiotypic suppression of chronic lymphocytic leukemia lymphocytes secreting monoclonal immunoglobulin M anti-sheep erythrocyte antibody. J Clin Invest (1980) 0.95
Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells. J Clin Invest (1996) 0.94
The effect of the parenteral administration of a rabbit anti-(mouse)-IgD serum on the immune response of mice to sheep erythrocytes. Immunology (1978) 0.92
Malignant lymphomas as tumours of the immune system. Br J Cancer (1980) 0.90
Biogenesis of membrane-bound and secreted immunoglobulins: two primary translation products of the human delta chain, differentially N-glycosylated to four discrete forms in vivo and in vitro. Proc Natl Acad Sci U S A (1981) 0.89
IgM-producing chronic lymphocytic leukemia cells undergo immunoglobulin isotype-switching without acquiring somatic mutations. J Clin Invest (1996) 0.89
Partial characterization of the shift from IgG to IgA synthesis in the clonal differentiation of human leukemic bone marrow-derived lymphocytes. J Exp Med (1975) 0.86
Simultaneous expression of mouse immunoglobulins M and D is determined by the same homolog of chromosome 12. Proc Natl Acad Sci U S A (1980) 0.85
Membrane-bound immunoglobulins on human leukemic cells. Evidence for humoral immune responses of patients to leukemia-associated antigens. J Clin Invest (1975) 0.83
Intracellular inclusion bodies in 14 patients with B cell lymphoproliferative disorders. J Clin Pathol (1984) 0.83
The idiotypic specificities of lymphocytes in human monoclonal gammopathies: analysis with the fluorescence activated cell sorter. Clin Exp Immunol (1983) 0.82
Henry G. Kunkel 1916-1983. An appreciation of the man and his scientific contributions & a bibliography of his research papers. J Exp Med (1985) 0.82
Phorbol ester-induced differentiation of chronic B lymphocytic leukaemia cells--regulatory impact of autologous and allogeneic accessory cells. Clin Exp Immunol (1985) 0.81
Biogenesis of membrane-bound and secreted immunoglobulins. II. Two forms of the human alpha chain translated in vitro and processed in vivo as distinct polypeptide chains. J Exp Med (1981) 0.81
Factors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells. Oncotarget (2015) 0.78
Phorbol myristate acetate, but not CD40L, induces the differentiation of CLL B cells into Ab-secreting cells. Immunol Cell Biol (2014) 0.78
Functional and phenotypic heterogeneity of electrophoretically separated leukaemic B cells from patients with chronic lymphocytic leukaemia. Clin Exp Immunol (1985) 0.78
Regulation of B cell lymphomagenesis by a malignant Qal+ inducer T cell clone. J Exp Med (1984) 0.77
Chronic lymphocytic leukemia cells diversify and differentiate in vivo via a nonclassical Th1-dependent, Bcl-6-deficient process. JCI Insight (2016) 0.76
IgD-Fc receptors on normal and neoplastic human B lymphocytes. Clin Exp Immunol (1982) 0.75
CD5 (Ly-1)-negative, conventional splenic B cells make a substantial contribution to the bromelain plaque-forming cell response in CBA and BW mice. Immunology (1990) 0.75
The Importance of an In-depth Study of Immunoglobulin Gene Rearrangements When Ascertaining the Clonal Relationship between Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma. Front Immunol (2016) 0.75
Inhibition of T cell-dependent human B cell proliferation and B cell differentiation by polyspecific monomeric IgG. Clin Exp Immunol (1987) 0.75
Structure and biological functions of human IgD. XII. Anti-IgD enhancement of PHA responsiveness in patients with chronic lymphocytic leukaemia. Clin Exp Immunol (1977) 0.75
Immunoglobulin spots on the surface of rabbit lymphocytes. J Exp Med (1970) 8.87
An immunofluorescence procedure for the detection of intracellular immunoglobulins. Clin Exp Immunol (1969) 4.77
Immunoglobulin D as a lymphocyte receptor. J Exp Med (1973) 4.62
Immunoglobulin and theta-bearing murine leukemias and lymphomas. J Immunol (1972) 3.41
Occurrence of surface IgM, IgD, and free light chains of human lymphocytes. J Exp Med (1974) 2.93
Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays. J Exp Med (1972) 2.47
Immunoglobulins on the surface of lymphoid cells in Waldenström's macroglobulinemia. J Clin Invest (1972) 2.15
Independent movement of IgD and IgM molecules on the surface of individual lymphocytes. J Immunol (1973) 2.03
IgD: a major immunoglobulin on the surface of lymphocytes from patients with chronic lymphatic leukemia. J Immunol (1974) 1.56
Multiple myeloma and benign monoclonal gammopathy: differentiation by immunofluorescence of lymphocytes. Ann Intern Med (1973) 1.43
B and T cell markers in human proliferative blood diseases and primary immunodeficiencies, with special reference to membrane bound immunoglobulins. Transplant Rev (1973) 1.41
Malignant lymphoma and lymphatic leukemia associated with myeloma-type serum proteins. Am J Med (1957) 1.26
The production of gamma G-globulin by lymphocytes in chronic lymphocytic leukemia. Immunocytologic investigation of a case. Blood (1966) 1.07
Chronic lymphatic leukemia associated with macroglobulinemia. Isr J Med Sci (1970) 0.90
The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1982) 67.54
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum (1987) 14.21
Immunological studies concerning the nephritis of systemic lupus erythematosus. J Exp Med (1967) 10.22
Interaction of aggregated -globulin with B lymphocytes. J Exp Med (1972) 9.29
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J Clin Invest (1966) 8.64
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus. J Immunol (1966) 7.40
Individual Antigenic Specificity of Isolated Antibodies. Science (1963) 7.27
Precipitin reactions of the C1q component of complement with aggregated gamma-globulin and immune complexes in gel diffusion. Immunology (1970) 6.89
Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers. J Exp Med (1968) 5.72
QUANTITATIVE ANTISTREPTOKINASE STUDIES IN PATIENTS INFECTED WITH GROUP A HEMOLYTIC STREPTOCOCCI: A COMPARISON WITH SERUM ANTISTREPTOLYSIN AND GAMMA GLOBULIN LEVELS WITH SPECIAL REFERENCE TO THE OCCURRENCE OF RHEUMATIC FEVER. J Clin Invest (1948) 5.25
Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis. Partial characterization and relationship to lowered complement levels. Clin Exp Immunol (1970) 5.10
Recognition by pregnancy serums of non-HL-A alloantigens selectively expressed on B lymphocytes. J Exp Med (1975) 4.96
Cross-idiotypic specificity among monoclonal IgM proteins with anti- -globulin activity. J Exp Med (1973) 4.93
IgG on lymphocyte surfaces; technical problems and the significance of a third cell population. J Immunol (1975) 4.92
Antibodies to polynucleotides in human sera: antigenic specificity and relation to disease. J Exp Med (1971) 4.62
Antigenic specificities related to the cold agglutinin activity of gamma M globulins. Science (1968) 4.32
Pneumocystis carinii pneumonia in the United States. Epidemiologic, diagnostic, and clinical features. Ann Intern Med (1974) 4.10
Galectins: a family of animal beta-galactoside-binding lectins. Cell (1994) 3.99
Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells. J Exp Med (1979) 3.76
Primary immunodeficiencies. Report of a World Health Organization Committee. Pediatrics (1971) 3.69
Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. Nature (1985) 3.68
CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J Exp Med (1990) 3.67
Human lymphocyte-sheep erythrocyte rosette formation: some characteristics of the interaction. Clin Immunol Immunopathol (1973) 3.55
Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen). J Exp Med (1985) 3.48
Evidence for linkage between HL-A histocompatibility genes and those involved in the synthesis of the second component of complement. J Exp Med (1974) 3.38
Opportunistic infections and immune deficiency in homosexual men. Ann Intern Med (1982) 3.29
Human mononuclear phagocyte differentiation antigens. I. Patterns of antigenic expression on the surface of human monocytes and macrophages defined by monoclonal antibodies. J Immunol (1983) 3.26
Human immunoglobulins: classes, subclasses, genetic variants, and idiotypes. Adv Immunol (1973) 3.25
Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies. J Clin Invest (1974) 3.24
Identification of human B and T lymphocytes by scanning electron microscopy. J Exp Med (1973) 3.21
Ia-bearing T lymphocytes in man. Their identification and role in the generation of allogeneic helper activity. J Exp Med (1978) 3.18
A subclass of human gamma-A-globulins (gamma-A2) which lacks the disulfied bonds linking heavy and light chains. J Exp Med (1968) 2.98
Occurrence of surface IgM, IgD, and free light chains of human lymphocytes. J Exp Med (1974) 2.93
Hidden rheumatoid factors with specificity for native gamma globulins. Arthritis Rheum (1966) 2.87
Lymphocytes in human immunodeficiency states: a study of membrane-associated immunoglobulins. Eur J Immunol (1971) 2.86
Studies of the Vi (gamma-2c) subgroup of gamma-globulin. A relationship between concentration and genetic type among normal individuals. J Exp Med (1967) 2.82
Expression of Ia-like antigen molecules on human granulocytes during early phases of differentiation. Proc Natl Acad Sci U S A (1977) 2.80
Peripheral blood Ia-positive T cells. Increases in certain diseases and after immunization. J Exp Med (1980) 2.76
Occurrence of -globulin complexes in serum and joint fluid of rheumatoid arthritis patients: use of monoclonal rheumatoid factors as reagents for their demonstration. J Exp Med (1971) 2.75
Studies with B-cell allo- and hetero-antisera: parallel reactivity and special properties. Scand J Immunol (1976) 2.74
Autologous mixed lymphocyte culture reactions and generation of cytotoxic T cells. J Exp Med (1977) 2.66
Nature of cold-reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus. Arthritis Rheum (1975) 2.65
Systemic lupus erythematosus: prototype of immune complex nephritis in man. J Exp Med (1971) 2.64
The human Ia system. Adv Immunol (1979) 2.62
Similarities in the light chains of anti-gamma-globulins showing cross-idiotypic specificities. J Exp Med (1974) 2.60
Serologic responses to Pneumocystis carinii antigens in health and disease. J Infect Dis (1990) 2.51
Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays. J Exp Med (1972) 2.47
Retracted Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity. Nature (1994) 2.43
C1g precipitins in the sera of patients with systemic lupus erythematosus and other hypocomplementemic states: characterization of high and low molecular weight types. J Exp Med (1971) 2.43
Antibodies to polynucleotides: distribution in human serums. Science (1969) 2.43
The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases. J Clin Invest (1973) 2.42
Human T cell activation. I. Monocyte-independent activation and proliferation induced by anti-T3 monoclonal antibodies in the presence of tumor promoter 12-o-tetradecanoyl phorbol-13 acetate. J Exp Med (1985) 2.41
Human dendritic cells: major stimulators of the autologous and allogeneic mixed leucocyte reactions. Clin Exp Immunol (1982) 2.41
Induction of in vitro differentiation and immunoglobulin synthesis of human leukemic B lymphocytes. J Exp Med (1978) 2.39
Immunoglobulins in chronic liver disease. Gut (1968) 2.39
Sheep red cell binding to human lymphocytes treated with neuraminidase; enhancement of T cell binding and identification of a subpopulation of B cells. J Exp Med (1973) 2.37
Genetic variation among Pneumocystis carinii hominis isolates in recurrent pneumocystosis. J Infect Dis (1995) 2.35
Stage-specific embryonic antigen involves alpha 1 goes to 3 fucosylated type 2 blood group chains. Nature (1981) 2.35
Growth characteristics and pathogenesis of experimental Pneumocystis carinii pneumonia. Infect Immun (1980) 2.33
Ia+ T cells in synovial fluid and tissues of patients with rheumatoid arthritis. Arthritis Rheum (1981) 2.30
Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes. J Immunol (1975) 2.28
Human T cell hybridomas secreting factors for IgA-specific help, polyclonal B cell activation, and B cell proliferation. J Exp Med (1982) 2.27
The joint-fluid gammaG-globulin complexes and their relationship to intraarticular complement dimunition. Ann N Y Acad Sci (1969) 2.26
Idiotype-like molecules on cells of a human T cell leukemia. J Exp Med (1983) 2.19
Aggregation of gamma-G3 proteins: relevance to the hyperviscosity syndrome. J Clin Invest (1970) 2.19
Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM. Proc Natl Acad Sci U S A (1993) 2.17
Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens. J Exp Med (1986) 2.17
Nude mouse: a new experimental model for Pneumocystis carinii infection. Science (1977) 2.16
The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias. J Exp Med (1975) 2.13
Lymphocyte binding of aggregated IgG and surface Ig staining in chronic lymphocytic leukaemia. Clin Exp Immunol (1973) 2.11