Published in J Exp Med on October 01, 1974
Two HLA-linked loci controlling the fourth component of human complement. Proc Natl Acad Sci U S A (1978) 3.05
Inherited structural polymorphism in human C2: evidence for genetic linkage between C2 and Bf. J Exp Med (1976) 2.89
Family study of the major histocompatibility complex in patients with systemic lupus erythematosus: importance of null alleles of C4A and C4B in determining disease susceptibility. Br Med J (Clin Res Ed) (1983) 2.86
Inherited deficiency of the second component of complement. Rheumatic disease associations. J Clin Invest (1976) 2.38
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man. Proc Natl Acad Sci U S A (1983) 2.23
Immunochemical characterization of murine H-2 controlled Ss (serum substance) protein through identification of its human homologue as the fourth component of complement. Proc Natl Acad Sci U S A (1975) 2.07
The purification and properties of the second component of human complement. Biochem J (1978) 2.03
Polymorphism of the human complement C4 and steroid 21-hydroxylase genes. Restriction fragment length polymorphisms revealing structural deletions, homoduplications, and size variants. J Clin Invest (1986) 2.00
Assignment of the structural gene for the third component of human complement to chromosome 19. Proc Natl Acad Sci U S A (1982) 2.00
A new antigen system expressed in human endothelial cells. J Clin Invest (1977) 1.79
Hereditary deficiency of the fifth component of complement in man. I. Clinical, immunochemical, and family studies. J Clin Invest (1976) 1.78
Hereditary C2 deficiency: Genetic studies and association with the HL-A system. J Exp Med (1975) 1.75
Nonspecific complement activation by streptococcal structures. II. Properdin-independent initiation of the alternate pathway. J Exp Med (1976) 1.64
The induction of macrophage spreading by factor B of the properdin system. J Exp Med (1979) 1.50
Mixed lymphocyte culture determinants and C2 deficiency: LD-7a associated with C2 deficiency in four families. J Exp Med (1975) 1.40
The genetic polymorphism of the fourth component of human complement: methodological aspects and a presentation of linkage and association data relevant to its localization in the HLA region. J Exp Med (1977) 1.38
Mapping of the structural gene for the second component of complement with respect to the human major histocompatibility complex. Am J Hum Genet (1979) 1.22
Genetic linkage between serum levels of the third component of complement and the H-2 complex. J Exp Med (1975) 1.20
Absence of the eighth component of complement in association with systemic lupus erythematosus-like disease. J Clin Invest (1977) 1.18
Structural heterogeneity of C2 Complement protein and its genetic variants in man: a new polymorphism of the HLA region. Proc Natl Acad Sci U S A (1977) 1.14
Murine complement component 3: genetic variation and linkage to H-2. Proc Natl Acad Sci U S A (1978) 1.07
Immunoglobulin deficiencies and susceptibility to infection among homozygotes and heterozygotes for C2 deficiency. J Clin Immunol (2003) 1.06
Genetic control of the eighth component of complement. J Clin Invest (1979) 1.03
Mapping of the immune response genes in the major histocompatibility complex of the Rhesus monkey. J Exp Med (1975) 1.02
Biosynthesis and secretion of the third component of complement by human endothelial cells in vitro. Immunology (1987) 1.01
Hereditary C7 deficiency. Diagnosis and HLA studies in a French-Canadian family. J Clin Invest (1977) 1.01
Simultaneous occurrence of hereditary C6 and C2 deficiency in a French-Canadian family. Immunology (1979) 1.01
Studies on murine Ss protein: demonstration that S region encodes structural gene for fourth component of complement. Proc Natl Acad Sci U S A (1979) 1.00
The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement. J Clin Invest (1976) 1.00
Streptococcal rheumatic carditis. Microbiol Rev (1983) 0.94
Vasculitis with probable familial C2 deficiency. (Case 1). Systemic lupus erythematosus with familial C2 deficiency. (Case 2). Proc R Soc Med (1977) 0.92
Complement-human histocompatibility antigen haplotypes in C2 deficiency. J Clin Invest (1981) 0.89
Murine binding protein of the fourth component of complement: structural polymorphism and its linkage to the major histocompatibility complex. Proc Natl Acad Sci U S A (1981) 0.88
HLA-linked complement polymorphisms (C2, BF) in psoriasis. Arch Dermatol Res (1983) 0.87
Studies on the C2-deficiency gene in man. Immunology (1980) 0.87
Studies on the murine Ss protein. I. Purification, molecular weight, and subunit structure. J Exp Med (1975) 0.83
Henry G. Kunkel 1916-1983. An appreciation of the man and his scientific contributions & a bibliography of his research papers. J Exp Med (1985) 0.82
Linkage studies in hereditary angio-oedema. J Med Genet (1979) 0.81
Quantitative differences between complement factor-B phenotypes. Immunology (1981) 0.81
Association of low C2 and C4 serum levels with the HLA-DW2 allele in healthy individuals. J Exp Med (1978) 0.79
Genetics of the complement system. J Med Genet (1975) 0.77
SLE-like and sicca symptoms in late component (C9) complement deficiency. Ann Rheum Dis (1987) 0.76
Editorial: Complement activation and disease. Br Med J (1976) 0.75
Molecular heterogeneity in deficiency of complement protein C2 type I. Immunology (1998) 0.75
Association of serum hemolytic complement levels with the major histocompatibility complex in chickens. J Exp Med (1976) 0.75
Renal transplantation in a patient with hereditary deficiency of the second component of complement. Clin Exp Immunol (1981) 0.75
Complement components and lymphoid cell surfaces. Proc R Soc Med (1976) 0.75
Histocompatibility matching. VI. Miniaturization of the mixed leukocyte culture test: a preliminary report. Transplantation (1971) 5.43
Ragweed hay fever: genetic control and linkage to HL-A haplotypes. Science (1972) 3.43
C2 deficiency. Development of lupus erythematosus. J Clin Invest (1973) 2.52
Receptors for immune complexes on lymphocytes. Adv Immunol (1974) 2.23
Immunological studies concerning the nephritis of systemic lupus erythematosus. J Exp Med (1967) 10.22
Interaction of aggregated -globulin with B lymphocytes. J Exp Med (1972) 9.29
Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus. J Clin Invest (1966) 8.64
Characteristics of a soluble nuclear antigen precipitating with sera of patients with systemic lupus erythematosus. J Immunol (1966) 7.40
Individual Antigenic Specificity of Isolated Antibodies. Science (1963) 7.27
Precipitin reactions of the C1q component of complement with aggregated gamma-globulin and immune complexes in gel diffusion. Immunology (1970) 6.89
Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers. J Exp Med (1968) 5.72
QUANTITATIVE ANTISTREPTOKINASE STUDIES IN PATIENTS INFECTED WITH GROUP A HEMOLYTIC STREPTOCOCCI: A COMPARISON WITH SERUM ANTISTREPTOLYSIN AND GAMMA GLOBULIN LEVELS WITH SPECIAL REFERENCE TO THE OCCURRENCE OF RHEUMATIC FEVER. J Clin Invest (1948) 5.25
Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis. Partial characterization and relationship to lowered complement levels. Clin Exp Immunol (1970) 5.10
Recognition by pregnancy serums of non-HL-A alloantigens selectively expressed on B lymphocytes. J Exp Med (1975) 4.96
Cross-idiotypic specificity among monoclonal IgM proteins with anti- -globulin activity. J Exp Med (1973) 4.93
IgG on lymphocyte surfaces; technical problems and the significance of a third cell population. J Immunol (1975) 4.92
Antibodies to polynucleotides in human sera: antigenic specificity and relation to disease. J Exp Med (1971) 4.62
Antigenic specificities related to the cold agglutinin activity of gamma M globulins. Science (1968) 4.32
Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells. J Exp Med (1979) 3.76
Primary immunodeficiencies. Report of a World Health Organization Committee. Pediatrics (1971) 3.69
CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J Exp Med (1990) 3.67
Human lymphocyte-sheep erythrocyte rosette formation: some characteristics of the interaction. Clin Immunol Immunopathol (1973) 3.55
Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen). J Exp Med (1985) 3.48
Ragweed hay fever: genetic control and linkage to HL-A haplotypes. Science (1972) 3.43
Human immunoglobulins: classes, subclasses, genetic variants, and idiotypes. Adv Immunol (1973) 3.25
Analyses of lymphocytes from patients with rheumatoid arthritis and systemic lupus erythematosus. Occurrence of interfering cold-reactive antilymphocyte antibodies. J Clin Invest (1974) 3.24
Identification of human B and T lymphocytes by scanning electron microscopy. J Exp Med (1973) 3.21
Ia-bearing T lymphocytes in man. Their identification and role in the generation of allogeneic helper activity. J Exp Med (1978) 3.18
A subclass of human gamma-A-globulins (gamma-A2) which lacks the disulfied bonds linking heavy and light chains. J Exp Med (1968) 2.98
Occurrence of surface IgM, IgD, and free light chains of human lymphocytes. J Exp Med (1974) 2.93
Infectious Mononucleosis: An Autopsy Report. Am J Pathol (1947) 2.88
Hidden rheumatoid factors with specificity for native gamma globulins. Arthritis Rheum (1966) 2.87
Lymphocytes in human immunodeficiency states: a study of membrane-associated immunoglobulins. Eur J Immunol (1971) 2.86
Studies of the Vi (gamma-2c) subgroup of gamma-globulin. A relationship between concentration and genetic type among normal individuals. J Exp Med (1967) 2.82
Complete genomic screen in Parkinson disease: evidence for multiple genes. JAMA (2001) 2.79
Peripheral blood Ia-positive T cells. Increases in certain diseases and after immunization. J Exp Med (1980) 2.76
Occurrence of -globulin complexes in serum and joint fluid of rheumatoid arthritis patients: use of monoclonal rheumatoid factors as reagents for their demonstration. J Exp Med (1971) 2.75
Autologous mixed lymphocyte culture reactions and generation of cytotoxic T cells. J Exp Med (1977) 2.66
Nature of cold-reactive antibodies to lymphocyte surface determinants in systemic lupus erythematosus. Arthritis Rheum (1975) 2.65
Systemic lupus erythematosus: prototype of immune complex nephritis in man. J Exp Med (1971) 2.64
The human Ia system. Adv Immunol (1979) 2.62
Similarities in the light chains of anti-gamma-globulins showing cross-idiotypic specificities. J Exp Med (1974) 2.60
Linkage studies in a large kindred with familial hypercholesterolemia. Am J Hum Genet (1974) 2.49
Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays. J Exp Med (1972) 2.47
Antibodies to polynucleotides: distribution in human serums. Science (1969) 2.43
The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases. J Clin Invest (1973) 2.42
Human T cell activation. I. Monocyte-independent activation and proliferation induced by anti-T3 monoclonal antibodies in the presence of tumor promoter 12-o-tetradecanoyl phorbol-13 acetate. J Exp Med (1985) 2.41
Human dendritic cells: major stimulators of the autologous and allogeneic mixed leucocyte reactions. Clin Exp Immunol (1982) 2.41
Induction of in vitro differentiation and immunoglobulin synthesis of human leukemic B lymphocytes. J Exp Med (1978) 2.39
Sheep red cell binding to human lymphocytes treated with neuraminidase; enhancement of T cell binding and identification of a subpopulation of B cells. J Exp Med (1973) 2.37
Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease. JAMA (2001) 2.36
Ia+ T cells in synovial fluid and tissues of patients with rheumatoid arthritis. Arthritis Rheum (1981) 2.30
Similar idiotypic specificity for the membrane IgD and IgM of human B lymphocytes. J Immunol (1975) 2.28
Human T cell hybridomas secreting factors for IgA-specific help, polyclonal B cell activation, and B cell proliferation. J Exp Med (1982) 2.27
The joint-fluid gammaG-globulin complexes and their relationship to intraarticular complement dimunition. Ann N Y Acad Sci (1969) 2.26
Linkage of HL-A and GBG. Vox Sang (1974) 2.23
Idiotype-like molecules on cells of a human T cell leukemia. J Exp Med (1983) 2.19
Aggregation of gamma-G3 proteins: relevance to the hyperviscosity syndrome. J Clin Invest (1970) 2.19
Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM. Proc Natl Acad Sci U S A (1993) 2.17
Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens. J Exp Med (1986) 2.17
The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias. J Exp Med (1975) 2.13
Idiotypic specificity of surface immunoglobulin and the maturation of leukemic bone-marrow-derived lymphocytes. Proc Natl Acad Sci U S A (1974) 2.13
Lymphocyte binding of aggregated IgG and surface Ig staining in chronic lymphocytic leukaemia. Clin Exp Immunol (1973) 2.11
Immunologic studies concerning the pulmonary lesions in Goodpasture's syndrome. Am J Pathol (1969) 2.11
Antibodies to a specific surface antigen of T cells in human sera inhibiting mixed leukocyte culture reactions. J Exp Med (1973) 2.11
Variable patterns of immunoglobulin and complement deposition in the kidneys of patients with systemic lupus erythematosus. Am J Pathol (1969) 2.11
Experimental approaches tohomogenous antibody populations. iIndividual antigenic specificity, cross specificity and diversity of human antibodies. Fed Proc (1970) 2.10
Production of tumor necrosis factor/cachectin by human B cell lines and tonsillar B cells. J Exp Med (1988) 2.07
An immunofluorescent study of the skin lesions in systemic lupus erythematosus. Arthritis Rheum (1966) 2.07
The 13q-deletion syndrome. Am J Hum Genet (1969) 2.06
Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody. J Exp Med (1988) 2.05
Hereditary C2 deficiency with some manifestations of systemic lupus erythematosus. J Immunol (1972) 2.02
Stimulation of human B lymphocytes by antibodies to IgM and IgG: functional evidence for the expression of IgG on B-lymphocyte surface membranes. Clin Immunol Immunopathol (1980) 2.00
Induction of polyclonal antibody synthesis by human allogeneic and autologous helper factors. J Exp Med (1979) 1.98
The nature of the stimulatory cell in human allogeneic and autologous MLC reactions; role of isolated IgM-bearing B cells. J Immunol (1979) 1.96
Neurofibrillary tangles in senile dementia of the Alzheimer type share an antigenic determinant with intermediate filaments of the vimentin class. Am J Pathol (1983) 1.93
Specific concentration of polynucleotide immune complexes in the cryoprecipitates of patients with systemic lupus erythematosus. J Clin Invest (1975) 1.91
Studies on DNA antibodies using DNA labelled with actinomycin-D (3H) or dimethyl (3H) sulphate. Clin Exp Immunol (1969) 1.88
Imbalances of gamma globulin subgroups and gene defects in patients with primary hypogammaglobulinemia. J Clin Invest (1970) 1.86
TWO MAJOR TYPES OF NORMAL 7S gamma-GLOBULIN. J Exp Med (1963) 1.86
CLASSIFICATION OF MYELOMA PROTEINS, BENCE JONES PROTEINS, AND MACROGLOBULINS INTO TWO GROUPS ON THE BASIS OF COMMON ANTIGENIC CHARACTERS. J Exp Med (1962) 1.84
Detection and functional studies of p60-65 (Tac antigen) on activated human B cells. J Exp Med (1984) 1.84
Sharing of individual antigenic determinants between a gamma G and a gamma M protein in the same myeloma serum. Proc Soc Exp Biol Med (1970) 1.79
Specific properties of human B and T lymphocytes and alterations in disease. Transplant Rev (1973) 1.79
Lymphoblastoid cell lines from patients with chronic lymphocytic leukemia: identification of tumor origin by idiotypic analysis. Proc Natl Acad Sci U S A (1978) 1.78
Alterations of estrogen metabolism in systemic lupus erythematosus. Arthritis Rheum (1979) 1.78
Genetic marker of the gamma-A2 subgroup of gamma-A immunoglobulins. Nature (1969) 1.76
Expression of Ia-like antigens on cultured human malignant melanoma cell lines. Proc Natl Acad Sci U S A (1978) 1.76