Published in J Exp Med on December 01, 1973
The modulation of lymphocyte functions by molecules secreted by macrophages. I. Description and partial biochemical analysis. J Exp Med (1975) 2.54
Secretory function of mononuclear phagocytes: a review. Am J Pathol (1976) 2.12
Regulation of B-lymphocyte clonal proliferation by stimulatory and inhibitory macrophage-derived factors. J Exp Med (1977) 1.67
Proliferation and differentiation of single hapten-specific B lymphocytes is promoted by T-cell factor(s) distinct from T-cell growth factor. Proc Natl Acad Sci U S A (1982) 1.53
Induction of guinea pig B-cell lymphokine synthesis by mitogenic and nonmitogenic signals to Fc, Ig, and C3 receptors. J Exp Med (1974) 1.53
Activation of mouse lymphocytes by anti-immunoglobulin. II. A thymus-independent response by a mature subset of B lymphocytes. J Exp Med (1978) 1.37
Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med (1976) 1.34
Immunocompetent cells in resistance to bacterial infections. Bacteriol Rev (1976) 1.31
The modulation of lymphocyte functions by molecules secreted by macrophages. II. Conditions leading to increased secretion. J Exp Med (1976) 1.30
The macrophage as a secretory cell in chronic inflammation. Agents Actions (1976) 1.18
Influence of reticuloendothelial blockade on the induction of tolerance and immunity by polysaccharides. Immunology (1976) 1.17
Functional characteristics of Peyer's patch cells. III. Carrier priming of T cells by antigen feeding. J Exp Med (1975) 1.13
Induction of immunological tolerance to a thymus-dependent antigen in the absence of thymus-derived cells. J Exp Med (1974) 1.12
B-cell activation by lipopolysaccharide. Distinct pathways for induction of mitosis and antibody production. J Exp Med (1977) 1.11
Influence of molecular structure of the tolerogenicity of bacterial dextrans. III. Dissociation between tolerance and immunity to the alpha1--6- and alpha1--3-linked epitopes of dextran B1355. Immunology (1975) 1.04
The inter-relationship of antigenic structure, thymus-independence and adjuvanticity. IV. A general model for B-cell induction. Immunology (1975) 0.92
The in vitro induction of immunological tolerance in the B lymphocyte by oligovalent thymus-dependent antigens. J Exp Med (1975) 0.85
Immunodepression in Taenia crassiceps infection: restoration of the in vitro response to sheep erythrocytes by activated peritoneal cells. Infect Immun (1978) 0.82
Mechanisms of action of 'lymphocyte activating factor' (LAF) I. Association of lymphocyte activating factor action with early DNA synthesis in PHA-stimulated lymphocytes. Immunology (1977) 0.80
Primary in vitro plaque-forming cell response to DAGG-Ficoll: LPS-induced enhancement mediated by interleukin-1. Immunology (1984) 0.78
Promotion of secondary anti-DNP antibody production in mice by type III pneumococcal polysaccharide (SIII) and dinitrophenylated rabbit antibody to SIII. Immunology (1975) 0.75
The mechanism of interaction between T and B lymphocytes in the in vitro response to sheep erythrocytes. Non-specific collaboration across a dialysis membrane. Immunology (1975) 0.75
Accessory cell function in immune responses in vivo: enhancing effect of radioresistant spleen cells on antibody response to SRBC in rats. Immunology (1980) 0.75
Further improvements in the plaque technique for detecting single antibody-forming cells. Immunology (1968) 24.83
The regulatory influence of activated T cells on B cell responses to antigen. Adv Immunol (1972) 9.43
Potentiation of the T-lymphocyte response to mitogens. II. The cellular source of potentiating mediator(s). J Exp Med (1972) 6.47
Critical role of determinant presentation in the induction of specific responses in immunocompetent lymphocytes. J Exp Med (1973) 5.30
Replacement of T-cell function by a T-cell product. Nat New Biol (1972) 5.20
The regulatory role of macrophages in antigenic stimulation. Adv Immunol (1972) 4.69
Carrier function in anti-hapten antibody responses. 3. Stimulation of antibody synthesis and facilitation of hapten-specific secondary antibody responses by graft-versus-host reactions. J Exp Med (1971) 4.29
Cell interactions in the immune response in vitro. V. Specific collaboration via complexes of antigen and thymus-derived cell immunoglobulin. J Exp Med (1972) 3.57
The mechanism of antigenic stimulation of primary and secondary clonal precursor cells. J Exp Med (1972) 3.41
Interaction between lymphocytes in immune responses. Cell Immunol (1971) 3.03
Induction of a hemolysin response in vitro. Interaction of cells of bone marrow origin and thymic origin. J Exp Med (1970) 2.49
Cell interactions in the immune response in vitro. IV. Comparison of the effects of antigen-specific and allogeneic thymus-derived cell factors. J Exp Med (1972) 2.48
A role of macrophages in the stimulation of immune responses by adjuvants. J Immunol (1969) 2.06
Cell surveillance model for lymphocyte cooperation. Nature (1971) 1.99
Mode of action of adjuvants: effects on antibody responses to macrophage-associated bovine serum albumin. J Immunol (1970) 1.79
Lymphocyte reactivity in vitro. II. Soluble reconstituting factor permitting response of purified lymphocyte. Cell Immunol (1970) 1.74
Thymus dependency of the immune response to hemocyanin: an evaluation of the role of macrophages in thymectomized mice. J Immunol (1970) 1.71
Cell-mediated immune response in vitro. I. A new in vitro system for the generation of cell-mediated cytotoxic activity. Cell Immunol (1972) 1.67
Specific heterologous enhancement of immune responses. 3. Partial characterization of supernatant material with enhancing activity. J Immunol (1972) 1.58
Immunological unresponsiveness of genetically thymusless (nude) mice. Eur J Immunol (1971) 1.46
Specific activation of the bone marrow-derived lymphocyte by antigen presented in a non-multivalent form. J Exp Med (1973) 1.46
The allogeneic effect in inbred mice. 3. Unique antigenic structural requirements in the expression of the phenomenon on unprimed cell populations in vivo. J Exp Med (1973) 1.35
The take-home lesson--1971. Ann N Y Acad Sci (1971) 1.33
Humoral and cell mediated responses in vitro of spleen cells from mice with thymic aplasia (nude mice). Aust J Exp Biol Med Sci (1972) 1.26
Lymphocyte interactions in antibody responses. Int Rev Cytol (1972) 1.21
INDUCTION OF MITOSIS IN MACROPHAGES BY ENDOTOXIN. J Immunol (1965) 1.06
Mitogenic factors produced by lymphocyte activation: effect on T- and B-cells. J Immunol (1972) 0.95
Uptake and degradation of a synthetic antigen by mouse macrophages containing different levels of lysosomal enzymes. Adv Exp Med Biol (1973) 0.81
Complement-derived leukotactic factors in pathological fluids. J Exp Med (1971) 0.80
Inducible expression of H-2 and Ia antigens on brain cells. Nature (1984) 3.48
Functional interactions of viral and histocompatibility antigens at tumor cell surfaces. Proc Natl Acad Sci U S A (1975) 2.39
Interferon-gamma induces enhanced expression of Ia and H-2 antigens on B lymphoid, macrophage, and myeloid cell lines. J Immunol (1983) 2.30
Participation of the H-2 antigens of tumor cells in their lysis by syngeneic T cells. J Exp Med (1976) 2.05
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J (1994) 1.97
The persisting (P) cell: histamine content, regulation by a T cell-derived factor, origin from a bone marrow precursor, and relationship to mast cells. Proc Natl Acad Sci U S A (1981) 1.97
Cell-mediated immune response in vitro. 3. The requirement for macrophages in cytotoxic reactions against cell-bound and subcellular alloantigens. J Exp Med (1972) 1.89
Automated chemical synthesis of a protein growth factor for hemopoietic cells, interleukin-3. Science (1986) 1.84
The regulation of growth and differentiation of a murine B cell lymphoma. II. The inhibition of WEHI 231 by anti-immunoglobulin antibodies. J Immunol (1981) 1.83
Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis. J Immunol (1991) 1.82
Effector cell blockade. A new mechanism of immune hyporeactivity induced by multivalent antigens. J Exp Med (1974) 1.75
Effect of cloned interferon-gamma on expression of H-2 and Ia antigens on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin. Eur J Immunol (1984) 1.73
The panspecific hemopoietin of activated T lymphocytes (interleukin-3). Annu Rev Immunol (1986) 1.57
Proliferation and differentiation of single hapten-specific B lymphocytes is promoted by T-cell factor(s) distinct from T-cell growth factor. Proc Natl Acad Sci U S A (1982) 1.53
Frequency of mast cell precursors in normal tissues determined by an in vitro assay: antigen induces parallel increases in the frequency of P cell precursors and mast cells. J Immunol (1983) 1.52
The role of T cells in IgG production; thymus-dependent antigens induce B cell memory in the absence of T cells. J Immunol (1975) 1.51
P cell-stimulating factor: biochemical characterization of a new T cell-derived factor. J Immunol (1981) 1.50
Pandemic H1N1 Influenza Infection and Vaccination in Humans Induces Cross-Protective Antibodies that Target the Hemagglutinin Stem. Front Immunol (2012) 1.50
p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein. Proc Natl Acad Sci U S A (1992) 1.46
Expression of the c-myc oncogene under control of an immunoglobulin enhancer in E mu-myc transgenic mice. Mol Cell Biol (1987) 1.46
Specific activation of the bone marrow-derived lymphocyte by antigen presented in a non-multivalent form. J Exp Med (1973) 1.46
A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities. Proc Natl Acad Sci U S A (1996) 1.45
Interferon-gamma induces the expression of H-2 and Ia antigens on brain cells. J Neuroimmunol (1985) 1.45
Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3. J Biol Chem (2000) 1.42
Intramucosal lymphocytes of the gut: Lyt-2 and thy-1 phenotype of the granulated cells and evidence for the presence of both T cells and mast cell precursors. J Immunol (1983) 1.31
Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. J Biol Chem (1994) 1.31
An examination of differences in serum antibody specificities and hypersensitivity reactions as contributing factors to chronic infection with the intestinal protozoan parasite, Giardia muris, in mice. Aust J Exp Biol Med Sci (1983) 1.30
Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3'-kinase. J Biol Chem (1994) 1.28
Purification to apparent homogeneity of a factor stimulating the growth of multiple lineages of hemopoietic cells. J Biol Chem (1984) 1.27
Interferon-gamma-like molecule induces Ia antigens on cultured mast cell progenitors. Proc Natl Acad Sci U S A (1982) 1.22
A con A-stimulated T-cell hybridoma releases factors affecting haematopoietic colony-forming cells and B-cell antibody responses. Nature (1980) 1.21
In vitro studies on lymphocyte differentiation. I. Long term in vitro culture of cells giving rise to functional lymphocytes in irradiated mice. J Exp Med (1978) 1.19
Tyrosine phosphorylation of receptor beta subunits and common substrates in response to interleukin-3 and granulocyte-macrophage colony-stimulating factor. J Biol Chem (1992) 1.15
Expression of Thy-1 antigen is not limited to T cells in cultures of mouse hemopoietic cells. Proc Natl Acad Sci U S A (1982) 1.15
Multiple hemopoietic growth factors stimulate activation of mitogen-activated protein kinase family members. J Immunol (1992) 1.14
Derivation of macrophage-like lines from the pre-B lymphoma ABLS 8.1 using 5-azacytidine. Nature (1982) 1.14
Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli. J Biol Chem (1998) 1.13
Induction of immunological tolerance to a thymus-dependent antigen in the absence of thymus-derived cells. J Exp Med (1974) 1.12
Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway. J Lipid Res (2001) 1.11
Delayed hypersensitivity in mast-cell-deficient mice. J Immunol (1983) 1.10
Multiple hemopoietins, with the exception of interleukin-4, induce modification of Shc and mSos1, but not their translocation. J Biol Chem (1994) 1.09
Nature of the T-cell receptor. Both the T-cell receptor and antigen-specific T-cell-derived factors are coded for by V genes but express anti-self idiotypes indirectly determined by major histocompatibility complex genes. Scand J Immunol (1979) 1.07
Hemopoietic growth factors with the exception of interleukin-4 activate the p38 mitogen-activated protein kinase pathway. J Biol Chem (1997) 1.07
Structure-function studies of human granulocyte-macrophage colony-stimulating factor. Identification of residues required for activity. J Immunol (1988) 1.07
Interleukin-4-dependent proliferation dissociates p44erk-1, p42erk-2, and p21ras activation from cell growth. J Biol Chem (1994) 1.06
Interferon-gamma enhances the expression of the major histocompatibility class I antigens on mouse pancreatic beta cells. Diabetes (1985) 1.06
Autogenous production of a hemopoietic growth factor, persisting-cell-stimulating factor, as a mechanism for transformation of bone marrow-derived cells. Proc Natl Acad Sci U S A (1983) 1.04
IL-4 inhibits the production of TNF-alpha and IL-12 by STAT6-dependent and -independent mechanisms. J Immunol (1999) 1.03
Bone marrow differentiation in vitro. Crit Rev Immunol (1983) 1.03
Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells. J Biol Chem (1997) 1.02
Ia antigens and associated invariant chain are induced simultaneously in lines of T-dependent mast cells by recombinant interferon-gamma. J Immunol (1984) 1.01
The regulation of growth and differentiation of a murine B cell lymphoma. I. Lipopolysaccharide-induced differentiation. J Immunol (1981) 1.01
Mechanism of effector-cell blockade. I. Antigen-induced suppression of Ig synthesis in a hybridoma cell line, and correlation with cell-associated antigen. J Exp Med (1980) 1.01
Antiviral antibodies inhibit the lysis of tumour cells by anti-H--2 sera. Nature (1976) 1.00
P-cell stimulating factor: characterization, action on multiple lineages of bone-marrow-derived cells and role in oncogenesis. Immunol Rev (1983) 1.00
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p38 map kinase regulates TNF-alpha production in human astrocytes and microglia by multiple mechanisms. Cytokine (2000) 0.99
Strategies for the analysis of accessory-cell function: the in vitro cloning and characterization of the P cell. Immunol Rev (1980) 0.97
Intracisternal A-type particle-mediated activations of cytokine genes in a murine myelomonocytic leukemia: generation of functional cytokine mRNAs by retroviral splicing events. Mol Cell Biol (1991) 0.96
Murine c-myc retroviruses alter the growth requirements of myeloid cell lines. Oncogene Res (1987) 0.95
The p38 mitogen-activated protein kinases can have opposing roles in the antigen-dependent or endotoxin-stimulated production of IL-12 and IFN-gamma. Eur J Immunol (2001) 0.95
Proprioceptive neuromuscular facilitation techniques in sports medicine: a reassessment. J Athl Train (1997) 0.95
Antibodies to transcobalamin II block in vitro proliferation of leukemic cells. Blood (1997) 0.94
The mechanism of bone marrow-derived (B) lymphocyte activation. I. Early events in antigen-induced triggering in the presence of polymerized flagellin. Eur J Immunol (1974) 0.94
Antagonism of B lymphocyte mitogenesis by anti-immunoglobulin antibody. J Immunol (1975) 0.94
Regulation of the immune response by IgM antibody: a paradoxical suppression of the in vitro primary immune response to sheep erythrocytes by passive IgM. Aust J Exp Biol Med Sci (1973) 0.94
In vivo transfer of persisting (P) cells; further evidence for their identity with T-dependent mast cells. J Immunol (1984) 0.93
In vitro studies on lymphocyte differentiation. II. Generation of terminal deoxynucleotidyl transferase-positive cells in long-term cultures of mouse bone marrow. J Immunol (1979) 0.93
Steel factor-induced tyrosine phosphorylation in murine mast cells. Common elements with IL-3-induced signal transduction pathways. J Immunol (1992) 0.93
A new, simple method for the preparation of lymphocytes bearing specific receptors. Eur J Immunol (1974) 0.93
T cell hybridoma-derived regulatory factors. I. Production of T cell growth factor following stimulation by concanavalin A. J Immunol (1981) 0.93
SHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substrates. J Biol Chem (1997) 0.92
Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin. J Biol Chem (1995) 0.92
Stimulation of bone marrow-derived and peritoneal macrophages by a T lymphocyte-derived hemopoietic growth factor, persisting cell-stimulating factor. Blood (1985) 0.89
Evidence for the presence in unimmunized mice of two populations of bone marrow derived B lymphocytes, defined by differences in adherence properties. Cell Immunol (1974) 0.88
Secretion of bioactive interleukin-1, interleukin-6, and colony-stimulating factors by human ovarian surface epithelium. Biol Reprod (1993) 0.87
Modulation of c-kit mRNA and protein by hemopoietic growth factors. Mol Cell Biol (1991) 0.87
A novel potential effector of M-Ras and p21 Ras negatively regulates p21 Ras-mediated gene induction and cell growth. Oncogene (2001) 0.87
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Activation of the stress-activated protein kinases by multiple hematopoietic growth factors with the exception of interleukin-4. Blood (1997) 0.86
Connective tissue mast cells in contact with fibroblasts express IL-3 mRNA. Analysis of single cells by polymerase chain reaction. J Immunol (1991) 0.86
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The mechanism of antigenic competition. I. The macrophage as a site of a reversible block of T-B lymphocyte collaboration. Eur J Immunol (1973) 0.85
The in vitro induction of immunological tolerance in the B lymphocyte by oligovalent thymus-dependent antigens. J Exp Med (1975) 0.85
Mechanism of antigenic competition. II. Induction by specific T cell products. Cell Immunol (1974) 0.85
The mechanism of bone marrow-derived (B) lymphocyte activation. II. A "second signal" for antigen-specific activation provided by flagellin and lipopolysaccharide. Eur J Immunol (1974) 0.85
Potentiation of delayed-type hypersensitivity by pertussigen or cyclophosphamide with release of different lymphokines. Immunology (1987) 0.84
Antipeptide antibodies define the NH2-terminal structure of the pan-specific hemopoietin interleukin 3. J Immunol (1987) 0.84
Characterization of hemopoietic growth factors from T cells and the myelomonocytic leukemia WEHI-3B. Exp Hematol (1985) 0.84
Role of a single haemopoietic growth factor in multiple proliferative disorders of haemopoietic and related cells. Lancet (1984) 0.84
B lymphocyte-antigen interactions in the initiation of tolerance or immunity. Transplant Rev (1975) 0.84
Expression of interleukin-1 beta gene in candidate human hematopoietic stem cells. Blood (1994) 0.83