Published in J Exp Med on January 01, 1976
TLRs and innate immunity. Blood (2008) 3.96
Increased production of superoxide anion by macrophages exposed in vitro to muramyl dipeptide or lipopolysaccharide. J Exp Med (1980) 3.13
Cellular requirements for lipopolysaccharide adjuvanticity. A role for both T lymphocytes and macrophages for in vitro responses to particulate antigens. J Exp Med (1979) 1.73
Genetic analysis of lymphocyte activation by lipopolysaccharide Endotoxin. Infect Immun (1976) 1.33
Effects of BCG infection on the susceptibility of mouse macrophages to endotoxin. Infect Immun (1979) 1.21
Immunologic responsiveness of the C3H/HeJ mouse: differential ability of butanol-extracted lipopolysaccharide (LPS) to evoke LPS-mediated effects. J Exp Med (1978) 1.13
Mitogenic activity of bacterial lipopolysaccharides in vivo: morphological and functinal characterization of responding cells. Infect Immun (1978) 1.10
Strain-dependent cytotoxic effects of endotoxin for mouse peritoneal macrophages. Infect Immun (1978) 1.09
Immunological responses of mice to lipopolysaccharide: lack of secondary responsiveness by C3H/HeJ mice. Infect Immun (1977) 1.09
Genetics of mouse mammary tumor virus-induced mammary tumors: linkage of tumor induction to the gag gene. J Virol (2000) 1.03
Analysis of the effects of lipopolysaccharide on macrophages: differential phagocytic responses of C3H/HeN and C3H/HeJ macrophages in vitro. Infect Immun (1979) 1.02
Peptides bound to proteosomes via hydrophobic feet become highly immunogenic without adjuvants. J Exp Med (1988) 0.95
Suppression of the immune response in C3H/HeJ mice by protein-free lipopolysaccharides. J Exp Med (1978) 0.94
Adjuvants for Leishmania vaccines: from models to clinical application. Front Immunol (2012) 0.92
Inheritance of lipopolysaccharide-enhanced nonspecific resistance to infection and of susceptibility to endotoxic shock in lipopolysaccharide low-responder mice. Infect Immun (1977) 0.87
Nocardia water-soluble mitogen and lipopolysaccharide. Comparative study of two adjuvants and B-cell mitogens in mice. Immunology (1977) 0.82
Biological activity of Bordetella pertussis in lipopolysaccharide-resistant mice. Infect Immun (1981) 0.75
Plaque Formation in Agar by Single Antibody-Producing Cells. Science (1963) 10.20
Potentiation of the T-lymphocyte response to mitogens. II. The cellular source of potentiating mediator(s). J Exp Med (1972) 6.47
Selective induction of DNA synthesis in T and B lymphocytes. Cell Immunol (1972) 4.94
PPD tuberculin--a B-cell mitogen. Nat New Biol (1972) 4.70
Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides. J Exp Med (1974) 4.48
Genetics of the antibody response to dextran in mice. Science (1972) 4.37
Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235. Biochemistry (1967) 4.22
Stimulation of B-lymphocytes by endotoxin. Reactions of thymus-deprived mice and karyotypic analysis of dividing cells in mice bearing T 6 T 6 thymus grafts. J Immunol (1972) 4.16
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
Requirement of thymus-dependent lymphocytes for potentiation by adjuvants of antibody formation. Nature (1971) 3.30
Immunologic properties of bacterial lipopolysaccharide (LPS): correlation between the mitogenic, adjuvant, and immunogenic activities. J Immunol (1975) 3.18
Effectiveness of lipid and lipidophilic substances as adjuvants. Nature (1961) 3.09
Activation of T and B lymphocytes in vitro. I. Regulatory influence of bacterial lipopolysaccharide (LPS) on specific T-cell helper function. J Exp Med (1974) 2.90
Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. Proc Natl Acad Sci U S A (1973) 2.61
Lipopolysaccharide can substitute for helper cells in the antibody response in vitro. Eur J Immunol (1972) 2.58
TOLERANCE TO A PROTEIN ANTIGEN IN ADULT MICE AND THE EFFECT OF NONSPECIFIC FACTORS. J Immunol (1963) 2.31
The use of bacterial lipopolysaccharides to show that two signals are required for the induction of antibody synthesis. J Exp Med (1973) 2.30
The possible biological significance of Fc receptors on mammalian lymphocytes and tumor cells. Cell (1974) 2.12
The role of humoral factors in the initiation of in vitro primary immune responses. II. Effects of lymphocyte mitogens. J Immunol (1973) 1.90
Genetic control of the immune response: the effect of non-H-2 linked genes on antibody production. J Immunol (1974) 1.77
Genetic control of B-cell responses. I. Selective unresponsiveness to lipopolysaccharide. Scand J Immunol (1975) 1.71
Cellular site of action of various adjuvants in antibody responses to hapten-carrier conjugates. J Immunol (1973) 1.62
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49
Studies on the induction of immunologic unresponsiveness. I. Effects of endotoxin and phytochemagglutinin. J Immunol (1967) 1.47
One non-specific signal triggers b lymphocytes. Transplant Rev (1975) 1.36
Genetic factors controlling anti-sheep erythrocyte antibody response and immunoglobulin synthesis in backcross and F2 progeny of mice genetically selected for "high" or "low" antibody synthesis. J Exp Med (1972) 1.26
The theory of the 'one nonspecific signal' model for b cell activation. Transplant Rev (1975) 1.21
The two signal model for b cell induction. Transplant Rev (1975) 1.12
Specific inhibition of endotoxin coating of red cells by a human erythrocyte membrane component. Infect Immun (1970) 1.09
Cellular events in tolerance. IV. The effect of a graft-versus-host reaction and endotoxin on hapten- and carrier-specific tolerance. Eur J Immunol (1974) 0.96
Selective effects of mitogens on subpopulations of mouse lymphoid cells. Cell Immunol (1974) 0.93
The genetic mechanisms that control the immune response and antigen recognition. Ann Immunol (Paris) (1974) 0.84
Meta-analysis of theory-of-mind development: the truth about false belief. Child Dev (2001) 11.06
Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence. J Exp Med (1984) 10.66
Continuous proliferation of murine antigen-specific helper T lymphocytes in culture. J Exp Med (1979) 7.20
The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes. Eur J Immunol (1984) 5.33
Biochemical and biological characterization of lymphocyte regulatory molecules. I. Purification of a class of murine lymphokines. J Exp Med (1979) 5.22
Lymphocyte specificity to protein antigens. I. Characterization of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice. J Immunol (1977) 4.67
Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides. J Exp Med (1974) 4.48
Biochemical and biological characterization of lymphocyte regulatory molecules. V. Identification of an interleukin 2-producing human leukemia T cell line. J Exp Med (1980) 4.32
Kinetic differences in unresponsiveness of thymus and bone marrow cells. Science (1971) 4.13
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
Systematic implementation of an advance directive program in nursing homes: a randomized controlled trial. JAMA (2000) 3.87
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med (1983) 3.52
ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes Dev (1999) 3.45
Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils. J Clin Invest (1975) 3.39
Biochemical characterization of lymphocyte regulatory molecules. II. Purification of a class of rat and human lymphokines. J Immunol (1980) 3.28
Immunologic properties of bacterial lipopolysaccharide (LPS): correlation between the mitogenic, adjuvant, and immunogenic activities. J Immunol (1975) 3.18
Generic inhalers for asthma. BMJ (1994) 3.09
Cellular sites of immunologic unresponsiveness. Proc Natl Acad Sci U S A (1970) 3.01
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J Cell Sci (1998) 2.83
Molecular and quantitative analysis of helper T cell-replacing factors on the induction of antigen-sensitive B and T lymphocytes. J Immunol (1979) 2.79
Immunological unresponsiveness. Adv Immunol (1973) 2.75
Immune response to Campylobacter pyloridis in patients with peptic ulceration. Lancet (1985) 2.64
Young people, alcohol, and designer drinks: quantitative and qualitative study. BMJ (1997) 2.64
Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. Proc Natl Acad Sci U S A (1973) 2.61
HCV-related fibrosis progression following liver transplantation: increase in recent years. J Hepatol (2000) 2.60
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56
Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol (1993) 2.56
Recent observations and concepts in immunological unresponsiveness and autoimmunity. Clin Exp Immunol (1971) 2.45
The genetic mapping of a defective LPS response gene in C3H/HeJ mice. J Immunol (1978) 2.43
Genetic control of antibody variable regions. Cold Spring Harb Symp Quant Biol (1977) 2.35
Active suppression of immunoglobulin allotype synthesis. II. Transfer of suppressing factor with spleen cells. J Exp Med (1972) 2.34
The use of bacterial lipopolysaccharides to show that two signals are required for the induction of antibody synthesis. J Exp Med (1973) 2.30
Enteroaggregative Escherichia coli heat-stable enterotoxin 1 represents another subfamily of E. coli heat-stable toxin. Proc Natl Acad Sci U S A (1993) 2.28
Analysis of autoimmunity through experimental models of thyroiditis and allergic encephalomyelitis. Adv Immunol (1980) 2.27
Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. J Exp Med (1975) 2.22
Interleukin 2: a class of T cell growth factors. Immunol Rev (1980) 2.21
Enterically induced immunologic tolerance. I. Induction of suppressor T lymphoyctes by intragastric administration of soluble proteins. J Immunol (1978) 2.17
Performance of an established system of first responder out-of-hospital defibrillation. The results of the second year of the Heartstart Scotland Project in the 'Utstein Style'. Resuscitation (1993) 2.17
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
Transfer of experimental autoimmune thyroiditis by serum from thyroidectomized donors. J Exp Med (1969) 2.12
An outbreak of multi-drug-resistant tuberculosis in a London teaching hospital. J Hosp Infect (1998) 2.10
Serum interleukin 6 levels in rheumatoid arthritis: correlations with clinical and laboratory indices of disease activity. Ann Rheum Dis (1993) 2.05
Dissociation of antigenicity and immunogenicity of neonatal epidermal allografts in the mouse. Transplantation (1990) 2.05
Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse. Nature (1975) 2.01
The production of thyroiditis and antibody following injection of unaltered thyroglobulin without adjuvant into rabbits previously stimulated with altered thyroglobulin. J Exp Med (1965) 1.96
The purification and quantitation of helper T cell-replacing factors secreted by murine spleen cells activated by concanavalin A. J Immunol (1979) 1.95
The T suppressor cell alloantigen Tsud maps near immunoglobulin allotype genes and may be an heavy chain constant-region marker on a T cell receptor. J Exp Med (1981) 1.94
The role of humoral factors in the initiation of in vitro primary immune responses. II. Effects of lymphocyte mitogens. J Immunol (1973) 1.90
Research Governance: a barrier to ethical research? QJM (2004) 1.89
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J Immunol (1993) 1.88
Propagation of antigen-specific T cell helper function in vitro. J Immunol (1979) 1.88
Disease progression in a cohort of infants with vertically acquired HIV infection observed from birth: the Women and Infants Transmission Study (WITS). J Acquir Immune Defic Syndr Hum Retrovirol (1998) 1.88
The production of antisera to human gammaGlobulin subclasses in rabbits using immunological unresponsiveness. J Immunol (1968) 1.82
Studies on the induction of immunologic unresponsiveness. 3. Antigen form and mouse strain variation. J Immunol (1969) 1.81
Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J Immunol (1990) 1.79
Biochemical and biologic characterization of lymphocyte regulatory molecules. III. The isolation and phenotypic characterization of Interleukin-2 producing T cell lymphomas. J Immunol (1980) 1.79
A survey of zoonotic pathogens carried by Norway rats in Baltimore, Maryland, USA. Epidemiol Infect (2007) 1.73
Ribavirin treatment for patients with chronic hepatitis C: results of a placebo-controlled study. J Hepatol (1996) 1.73
Lymphocyte specificity to protein antigens. II. Fine specificity of T-cell activation with cytochrome c and derived peptides as antigenic probes. J Exp Med (1979) 1.73
Cellular events during induction of immunologic unresponsiveness in adult mice. J Immunol (1971) 1.72
Studies on the induction of immunologic unresponsiveness. II. Kinetics. J Immunol (1967) 1.70
Cellular events in the induction of experimental allergic encephalomyelitis in rats. J Exp Med (1976) 1.69
Enteroaggregative Escherichia coli heat-stable enterotoxin is not restricted to enteroaggregative E. coli. J Infect Dis (1996) 1.69
Genetics of mouse antibodies. I. Linkage of the dextran response locus, VH-DEX, to allotype. Eur J Immunol (1975) 1.68
Ability of antigen-specific helper cells to effect a class-restricted increase in total Ig-secreting cells in spleens after immunization with the antigen. J Exp Med (1979) 1.65
The response of recombinant inbred strains of mice to bacterial lipopolysaccharides. J Immunol (1977) 1.64
c-myc oncogene expression in colorectal cancer. Cancer (1987) 1.60
Analysis of Photosynthetic Antenna Function in a Mutant of Arabidopsis thaliana (L.) Lacking trans-Hexadecenoic Acid. Plant Physiol (1985) 1.60
The genetic basis of antibody production: the dominant anti-arsonate idiotype response of the strain A mouse. Eur J Immunol (1982) 1.60
Efficacy of out of hospital defibrillation by ambulance technicians using automated external defibrillators. The Heartstart Scotland Project. Resuscitation (1992) 1.60
Helper T cell-replacing factors secreted by thymus-derived cells and macrophages: cellular requirements for B cell activation and synergistic properties. J Immunol (1979) 1.59
The cellular and subcellular bases of immunosenescence. Adv Immunol (1989) 1.59
Anesthesia for intranasal surgery: a comparison between tracheal intubation and the flexible reinforced laryngeal mask airway. Anesth Analg (1999) 1.59
Effectiveness of antismoking telephone helpline: follow up survey. BMJ (1997) 1.58
The role of humoral factors in the initiation of in vitro primary immune responses. 3. Characterization of factors that replace thymus-derived cells. J Immunol (1973) 1.55
Genetic control of the frequency of hematopoietic stem cells in mice: mapping of a candidate locus to chromosome 1. J Exp Med (1996) 1.51
Increased detection of Mycoplasma pneumoniae infection in children in England and Wales, October 2011 to January 2012. Euro Surveill (2012) 1.51
B-lymphocytes activation by the Fc region of IgG. J Exp Med (1977) 1.51
Cyclical production of antibody as a regulatory mechanism in the immune response. Adv Immunol (1975) 1.50
Toward a caring curriculum: a new pedagogy for nursing. NLN Publ (1989) 1.49
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49