Published in J Exp Med on August 01, 1974
Antigen-specific T-cell factor in cell cooperation: physical properties and mapping in the left-hand (K) half of H-2. J Exp Med (1974) 4.10
Evidence for identity or close association of the Fc receptor of B lymphocytes and alloantigens determined by the Ir region of the H-2 complex. J Exp Med (1974) 3.07
Properties of antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. I. In vivo activity and immunochemical characterization. J Exp Med (1975) 2.78
Collaboration of allogeneic T and B lymphocytes in the primary antibody response to sheep erythrocytes in vitro. J Exp Med (1975) 2.30
T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferation. J Exp Med (1976) 2.27
Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes. J Exp Med (1975) 2.14
Antigen-specific T-cell factors in the genetic control of the immune response to poly(Tyr,Glu)-polyDLAla--polyLys. Evidence for T- and B-cell defects in SJL mice. J Exp Med (1975) 1.98
T-lymphocyte-enriched murine peritoneal exudate cells. IV. Genetic control of cross-stimulation at the T-cell level. J Exp Med (1977) 1.40
Antibody response of C3H in equilibrium (CKB X CWB)F1 tetraparental mice to poly-L(Tyr,Glu)-poly-D,L-Ala-poly-L-Lys immunization. J Exp Med (1976) 1.23
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Genetic control of immune response. The dose of antigen given in aqueous solution is critical in determining which mouse strain is high responder to poly(LTyr, LGlu)-poly(LPro)--poly(LLys). J Exp Med (1975) 0.96
Immune response potential to poly(Tyr,Glu)-poly(DLAla)--poly(Lys) of human T cells of different donors. Proc Natl Acad Sci U S A (1981) 0.95
Sharing of Ia antigens between species. I. Detection of Ia specificities shared by rats and mice. J Exp Med (1977) 0.86
Partial purification and characterization of an antigen-specific helper factor synthesized by a T-cell continuous line. Proc Natl Acad Sci U S A (1983) 0.83
Transplantation behavior of A.TH and A.TL T-cell lymphomas in congenic resistant and hybrid strains. J Exp Med (1975) 0.82
Expression of a single major histocompatibility complex locus controls the immune response to poly-L-(tyrosine, glutamic acid)-poly-DL-alanine-poly-L-lysine. J Exp Med (1978) 0.81
Immunoregulation by mouse T-cell clones. II. The same H-Y-specific T helper clone can provide help for the generation of cytotoxic lymphocytes and antibody-secreting cells. Immunology (1985) 0.75
Antigenic competition between heterologous erythrocytes in mice. Immunological and histological studies exploring mechanisms of the antigenic competition. Immunology (1977) 0.75
Genetic control of the antibody response to poly(L Tyr, L Glu)-poly(DL Ala)--poly(L Lys) in mice: analysis of (low responder x low responder)F1 hybrids. Immunology (1982) 0.75
Histocompatibility-linked immune response genes. Science (1972) 16.79
Plaque Formation in Agar by Single Antibody-Producing Cells. Science (1963) 10.20
The regulatory influence of activated T cells on B cell responses to antigen. Adv Immunol (1972) 9.43
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A theory of self-nonself discrimination. Science (1970) 7.99
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The allogeneic effect on immune responses: model for regulatory influences of T lymphocytes on the immune system. Transplant Rev (1972) 5.23
Replacement of T-cell function by a T-cell product. Nat New Biol (1972) 5.20
Studies on the chemical basis of the antigenicity of proteins. 5. Synthesis, characterization and immunogenicity of some multichain and linear polypeptides containing tyrosine. Biochem J (1962) 4.82
Genetic control of the antibody response: relationship between immune response and histocompatibility (H-2) type. Science (1969) 4.53
Cell interactions between histoincompatible T and B lymphocytes. IV. Involvement of the immune response (Ir) gene in the control of lymphocyte interactions in responses controlled by the gene. J Exp Med (1973) 4.05
Genetic control of the antibody response in inbred mice. Transfer of response by spleen cells and linkage to the major histocompatibility (H-2) locus. J Exp Med (1968) 3.52
T cell factor which can replace T cells in vivo. Nature (1974) 3.10
Genetic control of the immune response. The effect of thymectomy on the primary and secondary antibody response of mice to poly-L(tyr, glu)-poly-D, L-ala--poly-L-lys. J Exp Med (1972) 3.06
Genetic control of the immune response. A selective defect in immunologic (IgG) memory in nonresponder mice. J Exp Med (1972) 2.60
Antigenicity of some new synthetic polypeptides and polypeptidyl gelatins. Biochem J (1964) 2.40
Role of optical configuration in the immunogenicity and specificity of synthetic antigens derived from multichain polyproline. J Biol Chem (1968) 2.19
Letter: T cell-dependent mediator in the immune response. Nature (1973) 1.94
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Genetic control of the immune response. Frequency and characteristics of antigen-binding cells in high and low responder mice. J Exp Med (1973) 1.55
Genetic control of the immune response. The effect of graft-versus-host reaction on the antibody response to poly-L(Tyr, Glu)-poly-D,L-Ala--poly-L-Lys in nonresponder mice. J Exp Med (1972) 1.42
Genetic control of immune responses. Curr Top Microbiol Immunol (1972) 1.34
Cellular studies of the genetic control of immune response toward the loop region of lysozyme. J Immunol (1973) 0.93
Dependence of the chemical nature of antibodies on the net electrical charge of antigens. Proc Natl Acad Sci U S A (1966) 2.25
Antigen-specific T-cell factors in the genetic control of the immune response to poly(Tyr,Glu)-polyDLAla--polyLys. Evidence for T- and B-cell defects in SJL mice. J Exp Med (1975) 1.98
Induction of a systemic lupus erythematosus-like disease in mice by a common human anti-DNA idiotype. Proc Natl Acad Sci U S A (1988) 1.91
Progressive immune dysfunction in cats experimentally infected with feline immunodeficiency virus. J Virol (1991) 1.83
Cellular sensitivity to collagen in thromboangiitis obliterans. N Engl J Med (1983) 1.79
The nature of the antigenic determinant in a genetic control of the antibody response. J Exp Med (1969) 1.74
The genetic control of antibody specificity. J Exp Med (1969) 1.58
In vitro proliferative responses and antibody titers specific to human acetylcholine receptor synthetic peptides in patients with myasthenia gravis and relation to HLA class II genes. J Clin Invest (1988) 1.57
The beneficial effect of the estrogen antagonist, tamoxifen, on experimental systemic lupus erythematosus. J Rheumatol (1994) 1.56
Thymus-independence of slowly metabolized immunogens. Proc Natl Acad Sci U S A (1972) 1.52
Autoimmune manifestations in the transforming growth factor-beta 1 knockout mouse. Blood (1996) 1.51
In vitro and in vivo induction of effector T cells mediating DTH responses to a protein and a synthetic polypeptide antigen. Cell Immunol (1979) 1.38
Genetic control of immune responses. Curr Top Microbiol Immunol (1972) 1.34
The effects of methotrexate on the production and activity of interleukin-1. Arthritis Rheum (1989) 1.28
Autoantibodies to a NR2A peptide of the glutamate/NMDA receptor in sera of patients with systemic lupus erythematosus. Ann Rheum Dis (2005) 1.24
The role of thymus cells in the immune response to poly(Tyr, Glu)-polyD L Ala--polyLys as a function of the genetic constitution of the mouse strain. Eur J Immunol (1974) 1.24
T-cell hybridoma bearing heavy chain variable region determinants producing (T,G)-A--L-specific helper factor. Nature (1980) 1.19
Thymus independence of a collagen-like synthetic polypeptide and of collagen, and the need for thymus and bone marrow-cell cooperation in the immune response to gelatin. J Exp Med (1974) 1.15
Genetic regulation of delayed-type hypersensitivity responses to poly(LTyr,LGu)-poly(DLAla)--poly(LLys). I. Expression of the genetic defect at two phases of the immune process. J Exp Med (1980) 1.11
Immune response of mice to nucleic acids: strain-dependent differences in magnitude and class of antibody production. J Immunol (1973) 1.10
The role of anti-idiotypic antibodies in the induction of experimental systemic lupus erythematosus in mice. Eur J Immunol (1989) 1.10
Resolution of mouse and human immunoglobulin G into two fractions by chromatography on diethylaminoethyl-sephadex. Relation of mouse antibody type to the antigen charge. Isr J Med Sci (1969) 1.10
Analysis of the biological functions and fine specificity of (T,G)-A--L specific T cell clones. Immunobiology (1986) 1.08
Pathogenic idiotypes of autoantibodies in autoimmunity: lessons from new experimental models of SLE. FASEB J (1990) 1.06
The effect of genetic control of immune response to synthetic polypeptides on the response to homologous DNP-polypeptide conjugates. Immunochemistry (1969) 1.05
The autoimmune response of different mouse strains to T-cell epitopes of the human acetylcholine receptor alpha subunit. Immunology (1990) 1.05
[Strain-dependent differences in the specificity of antibody responses toward lysozyme]. J Immunol (1971) 1.04
Role of antigenic structure in cell to cell cooperation. Proc Natl Acad Sci U S A (1976) 1.04
Linkage between immune response potential to DNA and X chromosome. Nature (1974) 1.03
Progression from acute to chronic disease in a murine parent-into-F1 model of graft-versus-host disease. J Immunol (2000) 1.03
The nature of murine immune response to nucleic acids. J Immunol (1975) 1.03
Activity of matrix metalloproteinase-9 is elevated in sera of patients with systemic lupus erythematosus. Clin Exp Immunol (2002) 1.02
Kinetics of cytokine production in experimental systemic lupus erythematosus: involvement of T helper cell 1/T helper cell 2-type cytokines in disease. J Immunol (1997) 1.01
Antigen-specific T cell factors: a fine analysis of specificity. J Immunol (1977) 1.01
In vitro correction of antigen-induced immune suppression: effects of histamine, dibutyryl cyclic AMP and cholera enterotoxin. Cell Immunol (1974) 1.01
Antigen specific T-cell helper factor cross reacts idiotypically with antibodies of the same specificity. Nature (1979) 1.01
The genetic regulation of the induction of experimental SLE. Immunology (1990) 1.00
Modulation of murine systemic lupus erythematosus with peptides based on complementarity determining regions of a pathogenic anti-DNA monoclonal antibody. Proc Natl Acad Sci U S A (1997) 1.00
(T,G)-A-L specific immune response potential and HLA typing of Israeli patients with systemic lupus erythematosus. Clin Exp Immunol (1985) 0.99
Cross-reactive idiotypic determinants on murine anti-(T,G)-A--L antibodies. J Immunol (1978) 0.99
A peptide composed of tandem analogs of two myasthenogenic T cell epitopes interferes with specific autoimmune responses. Proc Natl Acad Sci U S A (1997) 0.99
In vitro studies on H-2 linked unresponsiveness. 1. Normal helper cells to (T,G)-A-L and GAT in low and non-responder mice. Immunology (1977) 0.99
Beta 2-microglobulin-deficient background ameliorates lethal phenotype of the TGF-beta 1 null mouse. J Immunol (1999) 0.99
The mechanism by which a peptide based on complementarity-determining region-1 of a pathogenic anti-DNA auto-Ab ameliorates experimental systemic lupus erythematosus. Proc Natl Acad Sci U S A (2001) 0.98
The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment. Int Immunol (1995) 0.98
Cellular aspects of the inverse relationship between the net charge of immunogens of antibodies elicited. Proc Natl Acad Sci U S A (1970) 0.98
The role of the 16/6 idiotype network in the induction and manifestations of systemic lupus erythematosus. Int Immunol (1993) 0.97
Antigenic competition and genetic control of the immune response. A hypothesis for intramolecular competition. Cell Immunol (1973) 0.97
Role of MHC class I molecules in autoimmune disease. Crit Rev Immunol (1997) 0.97
Genetic control of immune response. The dose of antigen given in aqueous solution is critical in determining which mouse strain is high responder to poly(LTyr, LGlu)-poly(LPro)--poly(LLys). J Exp Med (1975) 0.96
The role of the human anti-DNA idiotype 16/6 in autoimmunity. Clin Immunol Immunopathol (1989) 0.95
The importance of the pathogenic 16/6 idiotype in the induction of SLE in naive mice. Scand J Immunol (1990) 0.95
Immune response potential to poly(Tyr,Glu)-poly(DLAla)--poly(Lys) of human T cells of different donors. Proc Natl Acad Sci U S A (1981) 0.95
Heterogeneity of the light chains of rabbit immunoglobulin G fractions and of a series of antibodies directed towards antigens of differing complexity. Immunochemistry (1967) 0.95
Autoantibodies to prostate specific antigen in patients with benign prostatic hyperplasia. J Urol (1995) 0.94
Inhibition of T-cell reactivity to myasthenogenic epitopes of the human acetylcholine receptor by synthetic analogs. Proc Natl Acad Sci U S A (1993) 0.94
Cellular studies of the genetic control of immune response toward the loop region of lysozyme. J Immunol (1973) 0.93
Genetic control of the murine cell-mediated immune response in vivo. II. H-2 linked responsiveness to the synthetic polypeptide poly(Tyr,Glu)-poly(DL-Ala)--poly(Lys). J Immunol (1975) 0.92
Immunological unresponsiveness induced in adult mice to synthetic polypeptides built on multichain polyproline and multichain polyalanine. Immunochemistry (1974) 0.92
Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice. Proc Natl Acad Sci U S A (2000) 0.92
Autoimmune mechanisms in thromboangiitis obliterans (Buerger's disease): the role of tobacco antigen and the major histocompatibility complex. Surgery (1992) 0.92
Prevention of systemic lupus erythematosus-like disease in (NZBxNZW)F1 mice by treating with CDR1- and CDR3-based peptides of a pathogenic autoantibody. J Clin Immunol (2000) 0.92
Sex hormone involvement in the induction of experimental systemic lupus erythematosus by a pathogenic anti-DNA idiotype in naive mice. J Rheumatol (1990) 0.91
Modulation of autoreactive responses of peripheral blood lymphocytes of patients with systemic lupus erythematosus by peptides based on human and murine anti-DNA autoantibodies. Clin Exp Immunol (2003) 0.91
The beneficial effects of treatment with tamoxifen and anti-oestradiol antibody on experimental systemic lupus erythematosus are associated with cytokine modulations. Immunology (1997) 0.90
Efficient genetically controlled formation of antibody to a synthetic antigen [poly(LTyr, LGlu)-poly(DLAla)- -poly(LLys)] covalently bound to a synthetic adjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine). Proc Natl Acad Sci U S A (1980) 0.90
Beneficial effects of the anti-oestrogen tamoxifen on systemic lupus erythematosus of (NZBxNZW)F1 female mice are associated with specific reduction of IgG3 autoantibodies. Ann Rheum Dis (2003) 0.90
Liposomes as immunological adjuvants in eliciting antibodies specific to the synthetic polypeptide poly(LTyr, LGlu)-poly(DLAla)--(LLys) with high frequency of site-associated idiotypic determinants. Eur J Immunol (1981) 0.90
Fine specificity of T cell lines and clones that are capable of inducing autoimmune manifestations in mice. Cell Immunol (1994) 0.90
In vitro correction of antigen-induced immune suppression: effects of poly(A) poly(U) and prostaglandin E. Cell Immunol (1973) 0.89
Periocular inflammation in mice with experimental systemic lupus erythematosus. A new experimental blepharitis and its modulation. J Immunol (1995) 0.89
Variable region sequences of autoantibodies from mice with experimental systemic lupus erythematosus. Eur J Immunol (1993) 0.89
Peptide analogs to pathogenic epitopes of the human acetylcholine receptor alpha subunit as potential modulators of myasthenia gravis. Proc Natl Acad Sci U S A (1996) 0.89
Binding of glycoprotein 120 and peptides from the HIV-1 envelope by autoantibodies in mice with experimentally induced systemic lupus erythematosus and in patients with the disease. AIDS Res Hum Retroviruses (1994) 0.89
Methimazole prevents induction of experimental systemic lupus erythematosus in mice. J Immunol (1994) 0.88
Comparison of the immune response potential of newborn mice to T-dependent and T-independent synthetic polypeptides. Immunology (1976) 0.88
Cellular analysis of the phenotypic correction of the genetically controlled low immune response to the polyproline determinant by macrophages. Cell Immunol (1974) 0.88
Ia-antigen-T-cell interactions for a thymus-independent antigen composed of D amino acids. Proc Natl Acad Sci U S A (1993) 0.88
Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNFalpha monoclonal antibody and by pentoxiphylline. Lupus (2001) 0.87
Studies on the mechanism of antigenic competition: analysis of competition between synthetic polypeptide antigens. Eur J Immunol (1972) 0.87
Elicitation of delayed-type hypersensitivity responses to poly(L-Tyr,LGlu)-poly(DLAla)--poly(LLys) by anti-idiotypic antibodies. J Exp Med (1980) 0.87
The nature of the active suppression of responses associated with experimental autoimmune myasthenia gravis by a dual altered peptide ligand administered by different routes. Proc Natl Acad Sci U S A (2001) 0.87
Altered peptide ligands of a myasthenogenic epitope as modulators of specific T-cell responses. Scand J Immunol (1996) 0.86
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Lymphocytes alloantigens associated with X-chromosome-linked immune response genes. Proc Natl Acad Sci U S A (1977) 0.86
Direct binding of a synthetic multichain polypeptide to class II major histocompatibility complex molecules on antigen-presenting cells and stimulation of a specific T-cell line require processing of the polypeptide. Proc Natl Acad Sci U S A (1991) 0.86
Lack of inverse relationship between the net charge of T-independent immunogens and the responding spleen cells. J Immunol (1975) 0.85
Establishment and characterization of continuous helper T cell lines specific to poly(LTyr,LGlu)-poly(DLAla)--poly(LLys). J Immunol (1981) 0.85
Single amino acid analogs of a myasthenogenic peptide modulate specific T cell responses and prevent the induction of experimental autoimmune myasthenia gravis. J Neuroimmunol (1998) 0.85
Linkage of murine (T,G)-A--L-specific idiotypic determinants to the heavy chain constant region allotypic markers. Immunogenetics (1980) 0.85
Amelioration of lupus manifestations by a peptide based on the complementarity determining region 1 of an autoantibody in severe combined immunodeficient (SCID) mice engrafted with peripheral blood lymphocytes of systemic lupus erythematosus (SLE) patients. Clin Exp Immunol (2004) 0.85