Published in Cell Immunol on November 01, 1973
Antigen stimulation of prostaglandin synthesis and control of immune responses. Proc Natl Acad Sci U S A (1976) 1.67
Antigen-stimulated changes in cyclic nucleotide levels in the mouse. Proc Natl Acad Sci U S A (1975) 0.86
Stimulation of monocyte cGMP by leukocyte dialysates. An antigen-independent property of dialyzable transfer factor. J Clin Invest (1975) 0.86
Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. Science (1984) 32.33
A TH1-->TH2 switch is a critical step in the etiology of HIV infection. Immunol Today (1993) 10.43
An evolutionary trace method defines binding surfaces common to protein families. J Mol Biol (1996) 9.31
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science (2000) 6.93
Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes. Eur J Immunol (1974) 6.20
G proteins: a family of signal transducers. Annu Rev Cell Biol (1986) 5.38
GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature (1989) 5.03
Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J Immunol (1991) 4.69
Two G protein oncogenes in human endocrine tumors. Science (1990) 4.46
Modulation of inflammation and immunity by cyclic AMP. Science (1974) 4.31
Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging. J Clin Invest (1989) 3.92
Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. I. T cell recognition of TNP in association with widely shared antigens. J Immunol (1978) 3.90
Role of the murine major histocompatibility complex in the specificity of in vitro T-cell-mediated lympholysis against chemically-modified autologous lymphocytes. Transplant Rev (1976) 3.87
Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha. Nature (1993) 3.57
The role of cyclic 3',5' adenosine monophosphate in the specific cytolytic activity of lymphocytes. J Immunol (1972) 3.51
Spatial control of actin polymerization during neutrophil chemotaxis. Nat Cell Biol (1999) 3.45
Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1. J Infect Dis (1992) 3.27
Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits. Nature (1994) 3.21
Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals. J Clin Invest (1993) 3.19
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus. J Clin Invest (1994) 3.12
Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts. Eur J Immunol (1977) 3.05
The Th1-Th2 hypothesis of HIV infection: new insights. Immunol Today (1994) 3.01
Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev (1996) 2.77
Pharmacologic control of allergic histamine release in vitro: evidence for an inhibitory role of 3',5'-adenosine monophosphate in human leukocytes. J Immunol (1972) 2.70
Preventable drug reactions--causes and cures. N Engl J Med (1971) 2.68
Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits. Nature (1992) 2.62
Dynamics of a chemoattractant receptor in living neutrophils during chemotaxis. Mol Biol Cell (1999) 2.61
Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products. Trends Cell Biol (2000) 2.59
Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F. Nature (1996) 2.55
Cellular differentiation of the immune system of mice. I. Separate splenic antigen-sensitive units for different types of anti-sheep antibody-forming cells. J Exp Med (1968) 2.51
Histamine augments leukocyte adenosine 3',5'-monophosphate and blocks antigenic histamine release. Science (1971) 2.47
Cytokine production patterns in cervical intraepithelial neoplasia: association with human papillomavirus infection. J Natl Cancer Inst (1997) 2.45
ADP-ribosylation of transducin by pertussis toxin blocks the light-stimulated hydrolysis of GTP and cGMP in retinal photoreceptors. J Biol Chem (1984) 2.39
Lipid modifications of trimeric G proteins. J Biol Chem (1995) 2.39
Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function. Nature (1994) 2.36
Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro. Science (1993) 2.35
Cyclic 3',5'-adenosine monophosphate in the human lukocyte: synthesis, degradation, andeffects n neutrophil candidacidal activity. J Clin Invest (1971) 2.35
Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors. Cell (1993) 2.34
Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence. Proc Natl Acad Sci U S A (1985) 2.34
A guanine nucleotide-sensitive adenylate cyclase in the yeast Saccharomyces cerevisiae. J Biol Chem (1983) 2.31
A model for the selective loss of major histocompatibility complex self-restricted T cell immune responses during the development of acquired immune deficiency syndrome (AIDS). J Immunol (1986) 2.31
Activation and depalmitoylation of Gs alpha. Cell (1994) 2.29
Dependence of the chemical nature of antibodies on the net electrical charge of antigens. Proc Natl Acad Sci U S A (1966) 2.25
An immunoendocrinological hypothesis of HIV infection. Lancet (1994) 2.19
Antigen-specific thymus cell factors in the genetic control of the immune response to poly-(tyrosyl, glutamyl)-poly-D, L-alanyl--poly-lysyl. J Exp Med (1974) 2.19
Detection of cytotoxic T lymphocytes specific for synthetic peptides of gp160 in HIV-seropositive individuals. J Immunol (1991) 2.17
Amino acid sequence of retinal transducin at the site ADP-ribosylated by cholera toxin. J Biol Chem (1984) 2.17
Effects of cholera enterotoxin on adenosine 3',5'-monophosphate and neutrophil function. Comparison with other compounds which stimulate leukocyte adenyl cyclase. J Clin Invest (1973) 2.16
Bifunctional major histocompatibility-linked genetic regulation of cell-mediated lympholysis to trinitrophenyl-modified autologous lymphocytes. J Exp Med (1975) 2.14
Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase. J Biol Chem (1978) 2.12
Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans. Ann Intern Med (1973) 2.11
Separate GTP binding and GTPase activating domains of a G alpha subunit. Science (1993) 2.08
Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels. Am J Cardiol (2000) 2.05
ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids. J Clin Invest (1995) 2.04
Improved computer-assisted digoxin therapy. A method using feedback of measured serum digoxin concentrations. Ann Intern Med (1975) 2.04
Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains. Proc Natl Acad Sci U S A (1986) 2.03
Adenyl cyclase in human leukocytes: evidence for activation by separate beta adrenergic and prostaglandin receptors. J Pharmacol Exp Ther (1971) 2.02
Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha. J Biol Chem (1993) 2.02
Receptors induce chemotaxis by releasing the betagamma subunit of Gi, not by activating Gq or Gs. Proc Natl Acad Sci U S A (1997) 1.99
Antigen-specific T-cell factors in the genetic control of the immune response to poly(Tyr,Glu)-polyDLAla--polyLys. Evidence for T- and B-cell defects in SJL mice. J Exp Med (1975) 1.98
cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J Biol Chem (1994) 1.98
Hemolytic plaque formation by leukocytes in vitro. Control by vasoactive hormones. J Clin Invest (1974) 1.98
Mutations in the GTP-binding site of GS alpha alter stimulation of adenylyl cyclase. J Biol Chem (1989) 1.95
Effects of cholera toxin on in vitro models of immediate and delayed hypersensitivity. Further evidence for the role of cyclic adenosine 3',5'-monophosphate. J Clin Invest (1973) 1.94
Early T-helper cell defects in HIV infection. AIDS (1991) 1.93
Induction of a systemic lupus erythematosus-like disease in mice by a common human anti-DNA idiotype. Proc Natl Acad Sci U S A (1988) 1.91
Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity. J Cell Biol (1992) 1.88
Mutant alpha subunits of Gi2 inhibit cyclic AMP accumulation. Nature (1991) 1.87
Major histocompatibility complex restricted cell-mediated immunity. Adv Immunol (1977) 1.86
Progressive immune dysfunction in cats experimentally infected with feline immunodeficiency virus. J Virol (1991) 1.83
CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells. J Immunol (1991) 1.82
Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals. Nature (1989) 1.80
Cellular sensitivity to collagen in thromboangiitis obliterans. N Engl J Med (1983) 1.79
Common epitope in human immunodeficiency virus (HIV) I-GP41 and HLA class II elicits immunosuppressive autoantibodies capable of contributing to immune dysfunction in HIV I-infected individuals. J Clin Invest (1989) 1.77
Family of G protein alpha chains: amphipathic analysis and predicted structure of functional domains. Protein Eng (1989) 1.76
Selection of a variant lymphoma cell deficient in adenylate cyclase. Science (1975) 1.76
Modelling of individual pharmacokinetics for computer-aided drug dosage. Comput Biomed Res (1972) 1.74
The nature of the antigenic determinant in a genetic control of the antibody response. J Exp Med (1969) 1.74
An 18,000 molecular weight polypeptide induces early events and stimulates DNA synthesis in cultured cells. Proc Natl Acad Sci U S A (1976) 1.74
B-cell alloantigens determined by the H-2 linked Ir region are associated with mixed lymphocyte culture stimulation. Science (1974) 1.73
Distinct events in the immune response elicited by transferred marrow and thymus cells. I. Antigen requirements and priferation of thymic antigen-reactive cells. J Exp Med (1969) 1.72
The Stanford Health Information Network for Education: integrated information for decision making and learning. Proc AMIA Annu Fall Symp (1997) 1.71
Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin. Science (1997) 1.71
Regulation of antibody response by cells expressing histamine receptors. J Exp Med (1972) 1.70
In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus. J Infect Dis (1995) 1.69
Defect of receptor-cyclase coupling protein in psudohypoparathyroidism. N Engl J Med (1980) 1.68
H-2-restricted cytotoxic effectors generated in vitro by the addition of trinitrophenyl-conjugated soluble proteins. J Exp Med (1978) 1.68