Published in Proc Natl Acad Sci U S A on October 01, 1974
Norepinephrine induces glial-specific enzyme activity in cultured plasma glioma cells. Proc Natl Acad Sci U S A (1977) 1.33
Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan-stimulated respiratory burst by 'type IV'-selective PDE inhibitors. Br J Pharmacol (1991) 1.26
Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2. Br J Pharmacol (1996) 1.23
Human synoviocytes: activation and desensitization by prostaglandins and 1-epinephrine. Proc Natl Acad Sci U S A (1975) 1.10
The mRNA encoding a high-affinity cAMP phosphodiesterase is regulated by hormones and cAMP. Proc Natl Acad Sci U S A (1989) 1.09
Desensitization of the beta-adrenoceptor of lymphocytes from normal subjects and asthmatic patients in vitro. Br J Clin Pharmacol (1978) 1.04
Vimentin: a phosphoprotein under hormonal regulation. J Cell Biol (1981) 0.98
Induction of cyclic AMP phosphodiesterase in Blastocladiella emersonii and its relation to cyclic AMP metabolism. J Bacteriol (1978) 0.85
Cyclic AMP-elevating agents prolong or inhibit eosinophil survival depending on prior exposure to GM-CSF. Br J Pharmacol (1996) 0.84
Lack of effect of zaprinast on methacholine-induced contraction and inositol 1,4,5-trisphosphate accumulation in bovine tracheal smooth muscle. Br J Pharmacol (1991) 0.79
In vitro model of retinal photoreceptor differentiation. Trans Am Ophthalmol Soc (1987) 0.79
The induction, desensitization and de-induction of tyrosine aminotransferase by 8-bromo-cyclic AMP in rat hepatoma cells. Biochem J (1988) 0.78
Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitors. Biochem J (1996) 0.77
Long-term effects of a high glucose concentration on cyclic nucleotide phosphodiesterase activity in mouse pancreatic islets maintained in tissue culture. Biochem J (1976) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
A protein binding assay for adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci U S A (1970) 23.79
Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochemistry (1971) 5.78
Cyclic 3',5'-nucleotide phosphodiesterase. Demonstration of an activator. Biochem Biophys Res Commun (1970) 3.18
Effects of lipolytic and antilipolytic substances on adenosine 3',5'-monophosphate levels in isolated fat cells. J Biol Chem (1968) 2.88
An effect of insulin on adipose-tissue adenosine 3':5'-cyclic monophosphate phosphodiesterase. Biochem J (1970) 2.07
Role of adenosine 3',5'-monophosphate in the effects of insulin and anti-insulin serum on liver metabolism. J Biol Chem (1968) 1.88
Regulation of adenosine 3',5'-cyclic monophosphate phosphodiesterase activity in fibroblasts by intracellular concentrations of cyclic adenosine monophosphate (3T3-dibutyryl cyclic AMP-SV40-transformed cells-michaelis constants-L cells-prostaglandin E 1 ). Proc Natl Acad Sci U S A (1972) 1.72
Prostaglandin E 1 effects on adenosine 3':5'-cyclic monophosphate concentration and phosphodiesterase activity in fibroblasts (mouse L cells-tissue culture-enzyme kinetics-prostaglandin homologues). Proc Natl Acad Sci U S A (1972) 1.68
Effect of catecholamines on the adenosine 3':5'-cyclic monophosphate concentrations of clonal satellite cells of neurons. Proc Natl Acad Sci U S A (1971) 1.65
A comparison of the effects of lipolytic and antilipolytic agents on adenosine 3',5'-monophosphate levels in adipose cells as determined by prior labeling with adenine-8-14C. J Biol Chem (1969) 1.56
An effect of insulin on cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in fat cells. J Biol Chem (1973) 1.46
Regulation of phosphodiesterase synthesis: requirement for cyclic adenosine monophosphate-dependent protein kinase. Science (1973) 1.09
The prevention of isoproterenol desensitization and isoproterenol reversal. J Pharmacol Exp Ther (1972) 1.06
Accumulation of adenosine 3':5'-cyclic monophosphate in clonal glial cells: labeling of intracellular adenine nucleotides with radioactive adenine. Proc Natl Acad Sci U S A (1972) 1.02
Glucocorticoid regulation of ACTH sensitivity of adenyl cyclase in rat fat cell membranes. Proc Natl Acad Sci U S A (1970) 0.97
Norepinephrine-sensitive properties of C-6 astrocytoma cells. Mol Pharmacol (1974) 0.93
Cyclic AMP phosphodiesterase activity at the external surface of intact skeletal muscles and stimulation of the enzyme by insulin. Arch Biochem Biophys (1973) 0.92
Effect of insulin and growth hormone on rat liver cyclic nucleotide phosphodiesterase. Biochemistry (1973) 0.91
Cyclic AMP phosphodiesterase in cloned astrocytoma cells: norepinephrine induces a specific enzyme form. Science (1973) 0.86
Adenosine 3',5'-monophosphate in glial tumor cells. Alterations by 5-bromodeoxyuridine. J Biol Chem (1973) 0.85
Gonadal hormones as regulators of pineal adenyl cyclase activity. Endocrinology (1970) 0.83
Cyclic 3',5'-AMP phosphodiesterase activity during cyclic AMP-induced differentiation of neuroblastoma cells in culture. Proc Soc Exp Biol Med (1973) 0.82
A comparison of three methods of glycogen measurement in tissues. Anal Biochem (1974) 2.83
Synthesis of nitric oxide in CNS glial cells. Trends Neurosci (1993) 2.81
Effects of changes in brain metabolism on the levels of citric acid cycle intermediates. J Biol Chem (1966) 2.59
High-titer human immunodeficiency virus type 1-based vector systems for gene delivery into nondividing cells. J Virol (1998) 2.47
The measurement of glycogen in tissues by amylo-alpha-1,4-alpha-1,6-glucosidase after the destruction of preexisting glucose. Anal Biochem (1975) 2.42
Nerve growth factor, laminin, and fibronectin promote neurite growth in human fetal sensory ganglia cultures. J Neurosci Res (1982) 2.28
The role of phosphofructokinase in metabolic regulation. Adv Enzyme Regul (1964) 2.08
Control of glucose utilization in working perfused rat heart. J Biol Chem (1994) 1.97
Kinetic evidence for multiple binding sites on phosphofructokinase. J Biol Chem (1966) 1.93
ELECTRON-SPIN RESONANCE STUDIES OF FREE-RADICAL INTERMEDIATES IN OXIDATION-REDUCTION ENZYME SYSTEMS. Proc Natl Acad Sci U S A (1958) 1.70
Quantitative histochemical analysis of glycolytic intermediates and cofactors with an oil well technique. J Histochem Cytochem (1968) 1.38
Metabolic correlates of fatigue and of recovery from fatigue in single frog muscle fibers. J Gen Physiol (1978) 1.37
Closed-head minimal traumatic brain injury produces long-term cognitive deficits in mice. Neuroscience (2003) 1.29
Factors affecting the turnover of cerebral glycogen and limit dextrin in vivo. J Neurochem (1973) 1.25
Control of glycogen levels in brain. J Neurochem (1968) 1.25
NFkappaB activation is required for the neuroprotective effects of pigment epithelium-derived factor (PEDF) on cerebellar granule neurons. J Biol Chem (2001) 1.16
Increase of proenkephalin mRNA and enkephalin content of rat striatum after daily injection of haloperidol for 2 to 3 weeks. Proc Natl Acad Sci U S A (1983) 1.16
Pigment epithelium-derived factor is a survival factor for cerebellar granule cells in culture. J Neurochem (1995) 1.16
Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death. J Neurosci Res (1998) 1.14
Glycogen, ammonia and related metabolities in the brain during seizures evoked by methionine sulphoximine. J Neurochem (1969) 1.13
Brain region and gene specificity of neuropeptide gene expression in cultured astrocytes. Science (1989) 1.09
Effects of changes in brain metabolism on levels of pentose phosphate pathway intermediates. J Biol Chem (1969) 1.08
Involvement of cytokines in normal CNS development and neurological diseases: recent progress and perspectives. J Neurosci Res (1998) 1.08
Phosphoglucomutase kinetics with the phosphates of fructose, glucose, mannose, ribose, and galactose. J Biol Chem (1969) 1.07
Altered nerve growth factor in fibroblasts from patients with familial dysautonomia. Proc Natl Acad Sci U S A (1980) 1.05
Pigment epithelium-derived factor protects cultured cerebellar granule cells against glutamate-induced neurotoxicity. J Neurochem (1997) 1.05
Glucose 1,6-diphosphate formation by phosphoglucomutase in mammalian tissues. J Biol Chem (1969) 1.05
Light-induced changes in energy metabolites, guanine nucleotides, and guanylate cyclase within frog retinal layers. J Biol Chem (1981) 1.04
Fatigue and metabolism of frog muscle fibers during stimulation and in response to caffeine. Am J Physiol (1981) 1.03
Effects of convulsants on energy reserves in the cerebral cortex. J Neurochem (1967) 1.03
Distribution of glucose and related metabolites in rat kidney. Am J Physiol (1968) 1.00
The effect of growth conditions on NAD+ and NADH concentrations and the NAD+:NADH ratio in normal and transformed fibroblasts. J Biol Chem (1974) 0.99
An enzymic method for measurement of glycogen. Anal Biochem (1967) 0.98
Cell culture models for reactive gliosis: new perspectives. J Neurosci Res (1998) 0.98
Energy metabolism in delayed neuronal death of CA1 neurons of the hippocampus following transient ischemia in the gerbil. Metab Brain Dis (1986) 0.98
The enzymatic measurement of adenine nucleotides and P-creatine in picomole amounts. Anal Biochem (1981) 0.97
Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine. Br J Pharmacol (1994) 0.96
Effect of exposure to anti-NGF on sensory neurons of adult rats and guinea pigs. Brain Res (1982) 0.96
Regional energy reserves in mouse brain and changes with ischaemia and anaesthesia. J Neurochem (1966) 0.96
Cyclic adenosine monphosphate, metabolites, and phosphorylase in neural tissue: a comparison a methods of fixation. Science (1973) 0.95
Substance P in the superior cervical ganglion and the submaxillary gland of the rat. Brain Res (1980) 0.95
Enkephalin biosynthesis in adrenal medulla. Modulation of proenkephalin mRNA content of cultured chromaffin cells by 8-bromo-adenosine 3',5'-monophosphate. Mol Pharmacol (1984) 0.94
An enzymic method for the measurement of inorganic phosphate. Anal Biochem (1967) 0.94
An in vitro amino acid incorporation method for assessing the status of in vivo protein synthesis. Anal Biochem (1984) 0.93
The kinetics of glycogen phosphorylases from brain and muscle. J Biol Chem (1967) 0.93
Norepinephrine-sensitive properties of C-6 astrocytoma cells. Mol Pharmacol (1974) 0.93
A high percentage yield of tyrosine hydroxylase-positive cells from rat E14 mesencephalic cell culture. Brain Res (1992) 0.93
Increase in nerve growth factor content of C6 glioma cells by the activation of a beta-adrenergic receptor. Brain Res (1977) 0.92
Putative neurotransmitters and cyclic nucleotides in prolonged ischemia of the cerebral cortex. Brain Res (1975) 0.92
The neurotoxicity of 1-methyl-4-phenylpyridinium in cultured cerebellar granule cells. J Neurosci (1989) 0.91
Pigment epithelium-derived factor (PEDF) has direct effects on the metabolism and proliferation of microglia and indirect effects on astrocytes. J Neurosci Res (1997) 0.91
Substrate changes in peripheral nerve during ischaemia and Wallerian degeneration. J Neurochem (1965) 0.91
Metabolic stability of hippocampal slice preparations during prolonged incubation. J Neurochem (1984) 0.90
Changes in brain metabolites induced by convulsants or electroshock: effects of anticonvulsant agents. Mol Pharmacol (1978) 0.90
Platelet-function studies in patients with glucose-6-phosphate dehydrogenase deficiency. Br J Haematol (1974) 0.90
Differential effects of chemical sympathectomy on expression and activity of tyrosine hydroxylase and levels of catecholamines and DOPA in peripheral tissues of rats. Neurochem Res (1999) 0.90
Protein kinase translocation following beta-adrenergic receptor activation in C6 glioma cells. J Biol Chem (1980) 0.89
Morphine alters preproenkephalin gene expression. Brain Res (1988) 0.89
The effect of volatile anaesthetics on levels of metabolites and on metabolic rate in brain. J Neurochem (1971) 0.89
Changes in brain energy metabolism and protein synthesis following transient bilateral ischemia in the gerbil. J Neurochem (1985) 0.89
Some recent refinements of quantitative histochemical analysis. Curr Probl Clin Biochem (1971) 0.88
Carbohydrate metabolites in rabbit hereditary ataxia. Arch Neurol (1966) 0.88
Regulation of nerve growth factor content in C6 glioma cells by beta-adrenergic receptor stimulation. Naunyn Schmiedebergs Arch Pharmacol (1977) 0.88
A culture model of reactive astrocytes: increased nerve growth factor synthesis and reexpression of cytokine responsiveness. J Neurochem (1998) 0.88
Studies on the hormone-sensitive lipase of adipose tissue. J Lipid Res (1971) 0.87
An in vitro model of ischemia: metabolic and electrical alterations in the hippocampal slice. J Neurosci (1984) 0.87
Substance P afferents from the habenula innervate the dorsal raphe nucleus. Exp Brain Res (1979) 0.87
Nimodipine levels in gerbil brain following parenteral drug administration. J Neurosurg (1985) 0.87
Relationships between energy reserves and function in rat superior cervical ganglion. J Neurochem (1969) 0.87
Increase in rat adrenal phenylethanolamine N-methyltransferase mRNA level caused by immobilization stress depends on intact pituitary-adrenocortical axis. J Neurochem (1994) 0.87
GABA receptors in clonal cell lines: a model for study of benzodiazepine action at molecular level. Science (1979) 0.86
Radiometric measurement of phosphoribosylpyrophosphate and ribose 5-phosphate by enzymatic procedures. Anal Biochem (1990) 0.86
Adenosine 3',5'-monophosphate in glial tumor cells. Alterations by 5-bromodeoxyuridine. J Biol Chem (1973) 0.85
The effects of altered endocrine states and of ether anaesthesia on mouse brain. J Neurochem (1971) 0.84
Hybridization approaches to the study of neuropeptides. Annu Rev Neurosci (1986) 0.84
Catecholamine-mediated elevation of cyclic GMP in the rat C-6 glioma cell line. J Cyclic Nucleotide Res (1976) 0.84
Immunoblastic lymphadenopathy: case report and literature review. Can Med Assoc J (1977) 0.84
Concentrations of energy metabolites and cyclic nucleotides during and after bilateral ischemia in the gerbil cerebral cortex. J Neurochem (1977) 0.84
Involvement of a high-affinity GTPase in the inhibitory coupling of striatal muscarinic receptors to adenylate cyclase. Mol Pharmacol (1983) 0.83
Regulation of glycogen metabolism in primary and transformed astrocytes in vitro. J Neurochem (1983) 0.83
Use of mRNA hybridization and radioimmunoassay to study mechanisms of drug-induced accumulation of enkephalins in rat brain structures. Mol Pharmacol (1985) 0.83
Developmental expression of the proenkephalin and prosomatostatin genes in cultured cortical and cerebellar astrocytes. Brain Res Dev Brain Res (1992) 0.83
In vivo portal-hepatic venous gradients of glycogenic precursors and incorporation of D-[3-3H]glucose into liver glycogen in the awake rat. J Biol Chem (1990) 0.83
The effects of intoxicating doses of ethanol upon intermediary metabolism in rat brain. J Neurochem (1972) 0.83
Regulation of glycogen metabolism in astrocytoma and neuroblastoma cells in culture. J Biol Chem (1976) 0.83
Alterations in striatal glial fibrillary acidic protein expression in response to 6-hydroxydopamine-induced denervation. Exp Brain Res (1993) 0.83
Increase of a nerve growth factor-like protein in the cerebellum of PCD mutant mice. J Neurosci Res (1982) 0.82
Effect of repeated cerebral ischemia on metabolites and metabolic rate in gerbil cortex. Brain Res (1977) 0.82
A modified cyclic AMP binding assay. Anal Biochem (1976) 0.82
Use of an experimental autoimmune model to define nerve growth factor dependency of peripheral and central substance P-containing neurons in the rat. J Neurosci (1981) 0.81
Cyclic nucleotides in murine brain: the temporal relationship of changes induced in adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate following maximal electroshock or decapitation. J Neurochem (1976) 0.81
In GH3 pituitary cells, acetylcholine and vasoactive intestinal peptide antagonistically modulate adenylate cyclase, cyclic AMP content, and prolactin secretion. Mol Pharmacol (1983) 0.81
Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: failure of aldose reductase inhibitors to modify myo-inositol depletion and dysmorphogenesis. Biochem Biophys Res Commun (1986) 0.81
Regulation of nerve growth factor content in a neuroblastoma cell line. Neuroscience (1978) 0.81
Reserpine changes the dynamic state of enkephalin stores in rat striatum and adrenal medulla by different mechanisms. J Neurosci (1985) 0.81
Effects of excitation-contraction uncoupling by stretch and hypertonicity on metabolism and tension in single frog muscle fibers. J Gen Physiol (1982) 0.81
An assessment of methods for measuremennt of glycogen synthetase activity including a new direct one-step assay. Anal Biochem (1973) 0.81
Perinatal opioids reduce striatal nerve growth factor content in rat striatum. Eur J Pharmacol (2001) 0.81