Published in C R Acad Sci Hebd Seances Acad Sci D on December 18, 1967
Abnormal DNA patterns in animal mitochondria: ethidium bromide-induced breakdown of closed circular DNA and conditions leading to oligomer accumulation. Proc Natl Acad Sci U S A (1970) 1.26
Effects of ethidium bromide on the cytochrome content and ultrastructure of L cell mitochondria. J Cell Biol (1971) 1.26
Abnormal circular DNA molecules induced by ethidium bromide in the kinetoplast of Trypanosoma cruzi. Proc Natl Acad Sci U S A (1969) 1.02
Characterization by sedimentation analysis of kinetoplast DNA from Trypanosoma cruzi at different stages of culture. Nucleic Acids Res (1979) 0.78
Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci U S A (1992) 3.27
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc Natl Acad Sci U S A (1995) 2.56
Characterization of a human ovarian adenocarcinoma line, IGROV1, in tissue culture and in nude mice. Cancer Res (1985) 2.06
Complete nucleotide sequence of minicircle kinetoplast DNA from Trypanosoma equiperdum. Proc Natl Acad Sci U S A (1981) 1.56
Electron microscopy of the circular kinetoplastic DNA from Trypanosoma cruzi: occurrence of catenated forms. Proc Natl Acad Sci U S A (1969) 1.49
Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance. Int J Cancer (1989) 1.35
Preparation and properties of nuclear and satellite deoxyribonucleic acid of Trypanosoma cruzi. J Mol Biol (1967) 1.31
Replicating, convalently closed, circular DNA from kinetoplasts of Trypanosoma cruzi. Proc Natl Acad Sci U S A (1972) 1.23
ATP-independent type II topoisomerase from trypanosomes. Proc Natl Acad Sci U S A (1986) 1.16
Strong association between c-myb and oestrogen-receptor expression in human breast cancer. Oncogene (1990) 1.16
Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis. Oncogene Res (1988) 1.16
Purification and characterization of Plasmodium berghei DNA topoisomerases I and II: drug action, inhibition of decatenation and relaxation, and stimulation of DNA cleavage. Biochemistry (1986) 1.11
Correlation of MDR1 gene expression with chemotherapy in neuroblastoma. J Natl Cancer Inst (1989) 1.08
C-myc proto-oncogene expression and prognosis in early carcinoma of the uterine cervix. Lancet (1987) 1.08
Expression of a human multidrug resistance gene in ovarian carcinomas. Cancer Res (1989) 1.06
Absence of kinetoplast DNA in a late antigenic variant of Trypanosoma equiperdum. Mol Biochem Parasitol (1980) 1.06
Abnormal circular DNA molecules induced by ethidium bromide in the kinetoplast of Trypanosoma cruzi. Proc Natl Acad Sci U S A (1969) 1.02
[Fractionation and characterization of desoxyribonucleic acid (DNA) of trypanosomes (Trypanosoma equiperdum)]. C R Acad Sci Hebd Seances Acad Sci D (1966) 1.00
Occurrence of a kinetoplast DNA-protein complex in Trypanosoma cruzi. Biochem Biophys Res Commun (1981) 0.97
Loss of heterozygosity, allele silencing and decreased expression of p73 gene in breast cancers: prevalence of alterations in inflammatory breast cancers. Oncogene (2000) 0.96
Combined analysis of DNA ploidy index and N-myc genomic content in neuroblastoma. Cancer Res (1991) 0.93
Coactivation of the MDR1 and MYCN genes in human neuroblastoma cells during the metastatic process in the nude mouse. Cancer Res (1994) 0.93
Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas. Br J Cancer (1990) 0.93
c-myc, p53 and bcl-2, apoptosis-related genes in infiltrating breast carcinomas: evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patients. Int J Cancer (1999) 0.92
[Study of kinetoplast DNA of Trypansoma cruzi using restriction endonucleases]. C R Acad Sci Hebd Seances Acad Sci D (1975) 0.90
c-erbB2 gene amplification and protein expression in ovarian epithelial tumors: evaluation of their respective prognostic significance by multivariate analysis. Int J Cancer (1995) 0.90
ATP-independent DNA topoisomerase II as potential drug target in trypanosomes. Biol Cell (1988) 0.89
Ultrastructural alterations of Trypanosoma cruzi kinetoplast induced by the interaction of a trypanocidal drug (hydroxystilbamidine) with the kinetoplast DNA. J Ultrastruct Res (1971) 0.89
In vivo stimulation by antitumor drugs of the topoisomerase II induced cleavage sites in c-myc protooncogene. Biochem Biophys Res Commun (1986) 0.89
Molecular organization of the kinetoplast DNA of Trypanosoma cruzi treated with berenil, a DNA interacting drug. J Ultrastruct Res (1972) 0.89
[DNA ultrastructure of the kinetoplast of Trypanosoma cruzi cultivated in vitro]. C R Acad Sci Hebd Seances Acad Sci D (1969) 0.88
[Presence of papillomavirus genomes and amplification of the c-myc and C-Ha-ras oncogenes in invasive cancers of the uterine cervix]. C R Acad Sci III (1984) 0.88
Circular oligomers in mitochondrial DNA of human and beef nonmalignant thyroid glands. Proc Natl Acad Sci U S A (1972) 0.88
Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation. Biochem Pharmacol (1993) 0.87
Prognostic value of c-myc proto-oncogene overexpression in early invasive carcinoma of the cervix. J Clin Oncol (1990) 0.86
Structure and expression of c-myc and c-fos proto-oncogenes in thyroid carcinomas. Br J Cancer (1988) 0.86
Association of c-erbB2-gene amplification with poor prognosis in non-inflammatory breast carcinomas but not in carcinomas of the inflammatory type. Int J Cancer (1994) 0.85
N-myc genomic content and DNA ploidy in stage IVS neuroblastoma. J Clin Oncol (1991) 0.85
[Ultrastructure of DNA alterations of Trypanosoma cruzi kinetoplasts treated with ethidium bromide]. C R Acad Sci Hebd Seances Acad Sci D (1969) 0.84
Study of molecular markers of resistance to m-AMSA in a human breast cancer cell line. Decrease of topoisomerase II and increase of both topoisomerase I and acidic glutathione S transferase. Biochem Pharmacol (1991) 0.84
[Mitochondrial DNA of malignant cells]. Bull Cancer (1971) 0.84
Restriction cleavage map of kinetoplast DNA minicircles from Trypanosoma equiperdum. Biochem Biophys Res Commun (1979) 0.84
Analysis of topoisomerase II-mediated DNA cleavage of the c-myc gene during HL60 differentiation. FEBS Lett (1993) 0.84
Expression of MDR1 and GST pi genes in 35 advanced neuroblastomas. Prog Clin Biol Res (1991) 0.84
Nuclear and kinetoplastic DNA from trypanosomes. J Protozool (1969) 0.84
Berenil induces the complete loss of kinetoblast DNA sequences in Trypanosoma equiperdum. Biochem Biophys Res Commun (1980) 0.83
Stimulation of the topoisomerase II induced DNA cleavage sites in the c-myc protooncogene by antitumor drugs is associated with gene expression. Biochemistry (1989) 0.83
Topoisomerase II-mediated DNA cleavage activity induced by ellipticines on the human tumor cell line N417. Biochem Pharmacol (1989) 0.83
Inhibitors of trypanosome topoisomerases. Biochem Soc Trans (1986) 0.83
p53 mediated tumor cell response to chemotherapeutic DNA damage: a preliminary study in matched pairs of breast cancer biopsies. Hum Pathol (1995) 0.82
Mutation and abnormal expression of the p53 gene in the viral skin carcinogenesis of epidermodysplasia verruciformis. J Invest Dermatol (2001) 0.82
[Inhibition by ellipticine derivatives of the reactions catalysed by the topoisomerases: preferential inhibition of topoisomerase II]. C R Seances Acad Sci III (1983) 0.82
Mitochondrial DNA from cells transformed by Avian myeloblastosis virus. Biochimie (1971) 0.82
Cisplatin-induced apoptosis and p53 gene status in a cisplatin-resistant human ovarian carcinoma cell line. Int J Cancer (1996) 0.82
Isolation and characterization of circular DNA molecules heterogeneous in size from a dyskinetoplastic strain of Trypanosoma equiperdum. Biochem Biophys Res Commun (1977) 0.81
Over-expression of MDR1 gene with no DNA amplification in a multiple-drug-resistant human ovarian carcinoma cell line. Int J Cancer (1989) 0.81
Specific inhibition by ethidium bromide of the incorporation of 3 H thymidine into the kinetoplastic DNA of Trypanosoma cruzi. Biochem Pharmacol (1970) 0.80
c-Ha-ras-1 polymorphism in human breast carcinomas: evidence for a normal distribution of alleles. Oncogene Res (1988) 0.80
Expression of the human fetal bac h19 gene in invasive cancers. Int J Oncol (1993) 0.80
[Buschke-Löwenstein tumor. 3 vulvar localizations. Association with HPV-6 in one case]. Ann Dermatol Venereol (1985) 0.79
[Trypanocidal activity of some ellipticine derivatives against Trypanosoma cruzi cultured in vitro]. C R Acad Sci Hebd Seances Acad Sci D (1975) 0.79
[Disappearance of DNA from the kinetoplast of Trypanosoma Cruzi cultivated in the presence of ethidium bromide]. C R Acad Sci Hebd Seances Acad Sci D (1968) 0.79
[Partial purification and characterization of nuclear DNA-topoisomerases from trypanosomes (author's transl)]. C R Seances Acad Sci III (1982) 0.78
Clinical significance of multiple drug resistance in human cancers. Anticancer Res (1990) 0.78
Tumorigenicity of cerebellar primitive neuro-ectodermal tumors in athymic mice correlates with poor prognosis in children. Int J Cancer (1996) 0.78
Characterization by sedimentation analysis of kinetoplast DNA from Trypanosoma cruzi at different stages of culture. Nucleic Acids Res (1979) 0.78
A specific inhibitor of type I DNA-topoisomerase of Trypanosoma cruzi: dimethyl-hydroxy-ellipticinium. Biochem Biophys Res Commun (1983) 0.78
[Oncocytes and oncocytomas. Histoenzymology, ultrastructure and description of the mitochondrial DNA]. Arch Anat Pathol (Paris) (1975) 0.78
[Importance of the extraction method in the isolation of DNA from Trypanosoma kinetoplast]. C R Acad Sci Hebd Seances Acad Sci D (1971) 0.78
Characterization of the topoisomerase II-induced cleavage sites in the c-myc proto-oncogene. In vitro stimulation by the antitumoral intercalating drug mAMSA. Biochem Pharmacol (1986) 0.78
In vitro chemical eradication of small cell lung cancer: application in autologous bone marrow transplantation. Eur J Cancer Clin Oncol (1988) 0.77
[Mechanism of action of trypanocide diamidines. Importance of base composition in the berenil-polynucleotides association]. C R Acad Sci Hebd Seances Acad Sci D (1970) 0.77
[A DNA topoisomerase from trypanosomes able to catenate, decatenate and unknot DNA without ATP]. C R Acad Sci III (1986) 0.77
[Analysis of the expression of the oncogene c-myc in human breast adenocarcinoma]. C R Acad Sci III (1985) 0.77
The early HPV16 proteins can regulate mRNA levels of cell cycle genes in human cervical carcinoma cells by p53-independent mechanisms. Virology (1998) 0.76
Combined analysis of DNA ploidy index and N-myc genomic content in neuroblastoma. Prog Clin Biol Res (1991) 0.76
Prognostic value of MDR1 gene expression in neuroblastoma: results of a multivariate analysis. Prog Clin Biol Res (1994) 0.76
Subunit organization of chromatin from trypanosoma cruzi sensitive and resistant to ethidium bromide. Mol Biochem Parasitol (1981) 0.76
Culture of clonogenic cells from various human tumors: drug sensitivity assay. Eur J Cancer Clin Oncol (1983) 0.75
Interaction of DNA intercalator 3-nitrobenzothiazolo (3,2-a)quinolinium with DNA topoisomerases: a possible-mechanism for its biological activity. Mol Pharmacol (1990) 0.75
[Chromosome anomalies in 2 cases of human ovarian cancer]. C R Acad Sci III (1986) 0.75
[Amplification of the expression of the c-myc oncogene in bronchial epidermoid carcinoma in man]. C R Acad Sci III (1985) 0.75
Soft agar clonogenic assay in human breast cancer. Neoplasma (1983) 0.75
[Expression of P-glycoprotein 170 (GP 170) and drug resistance in human cancers]. Bull Cancer (1990) 0.75
Decatenation of the kinetoplast DNA network of trypanosomes by a bacterial DNA-gyrase. Biochimie (1982) 0.75
[Mode of action of trypanocide diamidines. Association of berenil with nucleic acids in vitro]. C R Acad Sci Hebd Seances Acad Sci D (1970) 0.75
[Culture of clone-forming cells from human tumours and its practical applications (author's transl)]. Nouv Presse Med (1981) 0.75
A human small cell lung carcinoma cell line, resistant to 4'-(9-acridinylamino)-methanesulfon-m-anisidide and cross-resistant to camptothecin with a high level of topoisomerase I. Biochem Pharmacol (1994) 0.75
Effects of 9-hydroxy ellipticine on in vitro transcription of Trypanosoma cruzi DNAs. Biochem Biophys Res Commun (1977) 0.75
Nuclear and mitochondrial origin of rat liver double-stranded RNA. Biochimie (1975) 0.75
[In vitro culture of clonogenic cells from various human tumors: chemosensitivity tests]. Bull Cancer (1984) 0.75
[Study, at the gene level, of the activation of topoisomerase II by antitumor agents]. Pathol Biol (Paris) (1987) 0.75
[The expression of c-myb is strongly associated with the presence of estrogen and progesterone receptors in breast cancer]. C R Acad Sci III (1988) 0.75
[Fractionation and characterization of 2 satellite bands of DNA in Trypanosoma gambiense]. C R Acad Sci Hebd Seances Acad Sci D (1967) 0.75
[Activation of N-myc oncogene and associated genes to chemoresistance, prognostic value for neuroblastoma]. Bull Cancer (1991) 0.75
Relapse from a stage IV-S neuroblastoma and N-myc amplification. Eur J Cancer Clin Oncol (1989) 0.75
The kinetoplast of DNA of Trypanosoma gambiense: comparison with the kDNA of Trypanosoma equiperdum. Biochimie (1981) 0.75
[Attempted demonstration of sequences common to kinetoplastic and nuclear DNA in Trypanosoma]. C R Acad Sci Hebd Seances Acad Sci D (1973) 0.75