Published in J Mol Biol on September 14, 1967
Electron microscopy of the circular kinetoplastic DNA from Trypanosoma cruzi: occurrence of catenated forms. Proc Natl Acad Sci U S A (1969) 1.49
Circular deoxyribonucleic acid from Shigella dysenteriae Y6R. J Bacteriol (1969) 1.36
Replicating, convalently closed, circular DNA from kinetoplasts of Trypanosoma cruzi. Proc Natl Acad Sci U S A (1972) 1.23
Evidence for the retention of kinetoplast DNA in an acriflavine-induced dyskinetoplastic strain of Trypanosoma brucei which replicates the altered central element of the kinetoplast. J Cell Biol (1971) 1.17
Electron microscopy of kinetoplastic DNA from Trypanosoma mega. Proc Natl Acad Sci U S A (1970) 1.14
Abnormal circular DNA molecules induced by ethidium bromide in the kinetoplast of Trypanosoma cruzi. Proc Natl Acad Sci U S A (1969) 1.02
Kinetoplast deoxyribonucleic acid of the hemoflagellate Trypanosoma lewisi. J Cell Biol (1970) 0.94
Kinetoplast and other satellite DNAs of kinetoplastic and dyskinetoplastic strains of Trypanosoma. J Cell Biol (1971) 0.92
Fine structure and replication of the kinetoplast of Trypanosoma lewisi. J Cell Biol (1968) 0.84
Characterization by sedimentation analysis of kinetoplast DNA from Trypanosoma cruzi at different stages of culture. Nucleic Acids Res (1979) 0.78
A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization. J Mol Biol (1967) 10.36
A new fluorometric method for RNA and DNA determination. Anal Biochem (1966) 6.74
cis elements and trans-acting factors involved in dimer formation of murine leukemia virus RNA. J Virol (1990) 3.40
Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci U S A (1992) 3.27
Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses. Eur J Cancer (1991) 2.79
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc Natl Acad Sci U S A (1995) 2.56
Characterization of a new class of circular DNA molecules in yeast. Biochem Biophys Res Commun (1971) 2.33
Characterization of a human ovarian adenocarcinoma line, IGROV1, in tissue culture and in nude mice. Cancer Res (1985) 2.06
alpha-DNA II. Synthesis of unnatural alpha-anomeric oligodeoxyribonucleotides containing the four usual bases and study of their substrate activities for nucleases. Nucleic Acids Res (1987) 2.06
Transient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugs. Biochem Pharmacol (1988) 1.91
Control of UV induction of recA protein. Proc Natl Acad Sci U S A (1983) 1.68
An analytical study of the dimerization of in vitro generated RNA of Moloney murine leukemia virus MoMuLV. Nucleic Acids Res (1990) 1.62
Introduction of definite amounts of nonpermeant molecules into living cells after electropermeabilization: direct access to the cytosol. Exp Cell Res (1988) 1.57
Complete nucleotide sequence of minicircle kinetoplast DNA from Trypanosoma equiperdum. Proc Natl Acad Sci U S A (1981) 1.56
alpha-DNA. VI: Comparative study of alpha- and beta-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition. Nucleic Acids Res (1987) 1.53
[Electrochemotherapy, a new antitumor treatment: first clinical trial]. C R Acad Sci III (1991) 1.52
Electron microscopy of the circular kinetoplastic DNA from Trypanosoma cruzi: occurrence of catenated forms. Proc Natl Acad Sci U S A (1969) 1.49
Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance. Int J Cancer (1989) 1.35
Electrochemotherapy of spontaneous mammary tumours in mice. Eur J Cancer (1991) 1.26
Replicating, convalently closed, circular DNA from kinetoplasts of Trypanosoma cruzi. Proc Natl Acad Sci U S A (1972) 1.23
The use of ethidium bromide-circular DNA complexes for the fluorometric analysis of breakage and joining of DNA. J Mol Biol (1971) 1.23
Smoking cessation rates 4 years after treatment by nicotine gum and acupuncture. Prev Med (1997) 1.22
Purification and characterization of recA protein from salmonella typhimurium. J Biol Chem (1983) 1.20
A new antitumoral agent: 9-hydroxyellipticine. Possibility of a rational design of anticancerous drugs in the series of DNA intercalating drugs. Proc Natl Acad Sci U S A (1974) 1.18
ATP-independent type II topoisomerase from trypanosomes. Proc Natl Acad Sci U S A (1986) 1.16
Strong association between c-myb and oestrogen-receptor expression in human breast cancer. Oncogene (1990) 1.16
Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis. Oncogene Res (1988) 1.16
[Interaction of ethidium hydrobromate (EH) with polyribonucleotides. Applications to the study of hybridization reactions]. C R Acad Sci Hebd Seances Acad Sci D (1965) 1.15
Purification and characterization of Plasmodium berghei DNA topoisomerases I and II: drug action, inhibition of decatenation and relaxation, and stimulation of DNA cleavage. Biochemistry (1986) 1.11
Correlation of MDR1 gene expression with chemotherapy in neuroblastoma. J Natl Cancer Inst (1989) 1.08
C-myc proto-oncogene expression and prognosis in early carcinoma of the uterine cervix. Lancet (1987) 1.08
Expression of a human multidrug resistance gene in ovarian carcinomas. Cancer Res (1989) 1.06
Absence of kinetoplast DNA in a late antigenic variant of Trypanosoma equiperdum. Mol Biochem Parasitol (1980) 1.06
Initial degradation of deoxyribonucleic acid after injection in mammals. Cancer Res (1965) 1.06
Comparative activity of alpha- and beta-anomeric oligonucleotides on rabbit beta globin synthesis: inhibitory effect of cap targeted alpha-oligonucleotides. Biochem Biophys Res Commun (1989) 1.05
A protein inhibitor of acid deoxyribonucleases. Proc Natl Acad Sci U S A (1969) 1.03
VanA-type enterococci from humans, animals, and food: species distribution, population structure, Tn1546 typing and location, and virulence determinants. Appl Environ Microbiol (2007) 1.03
Abnormal circular DNA molecules induced by ethidium bromide in the kinetoplast of Trypanosoma cruzi. Proc Natl Acad Sci U S A (1969) 1.02
[Fractionation and characterization of desoxyribonucleic acid (DNA) of trypanosomes (Trypanosoma equiperdum)]. C R Acad Sci Hebd Seances Acad Sci D (1966) 1.00
Occurrence of a kinetoplast DNA-protein complex in Trypanosoma cruzi. Biochem Biophys Res Commun (1981) 0.97
Alpha-DNA VIII: thermodynamic parameters of complexes formed between the oligo-alpha-deoxynucleotides: alpha-d(GGAAGG) and alpha-d(CCTTCC) and their complementary oligo-beta-deoxynucleotides: beta-d(CCTTCC) and beta-d(GGAAGG) are different. Nucleic Acids Res (1989) 0.96
Loss of heterozygosity, allele silencing and decreased expression of p73 gene in breast cancers: prevalence of alterations in inflammatory breast cancers. Oncogene (2000) 0.96
Alpha-DNA. IV: Alpha-anomeric and beta-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physicochemical properties and poly (rA) binding. Nucleic Acids Res (1987) 0.96
[Induction of a "dyskinetoplast" by ethidium bromide in Trypanosoma cruzi cultivated in vitro]. C R Acad Sci Hebd Seances Acad Sci D (1967) 0.94
Antitumor activity, pharmacology, and toxicity of ellipticines, ellipticinium, and 9-hydroxy derivatives: preliminary clinical trials of 2-methyl-9-hydroxy ellipticinium (NSC 264-137). Recent Results Cancer Res (1980) 0.94
Potential antitumor agents: synthesis and biological properties of aliphatic amino acid 9-hydroxyellipticinium derivatives. J Med Chem (1984) 0.93
Combined analysis of DNA ploidy index and N-myc genomic content in neuroblastoma. Cancer Res (1991) 0.93
Coactivation of the MDR1 and MYCN genes in human neuroblastoma cells during the metastatic process in the nude mouse. Cancer Res (1994) 0.93
Analysis of the c-Ha-ras-1 gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas. Br J Cancer (1990) 0.93
c-myc, p53 and bcl-2, apoptosis-related genes in infiltrating breast carcinomas: evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patients. Int J Cancer (1999) 0.92
Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative. Nucleic Acids Res (1991) 0.92
Circulating tumour cells: insights into tumour heterogeneity. J Intern Med (2013) 0.91
Ellipticine and derivatives induce breakage of L1210 cells DNA in vitro. Biochem Pharmacol (1979) 0.91
An immunoradiometric quantitative assay of Escherichia coli recA protein. Biochimie (1982) 0.91
[Study of kinetoplast DNA of Trypansoma cruzi using restriction endonucleases]. C R Acad Sci Hebd Seances Acad Sci D (1975) 0.90
c-erbB2 gene amplification and protein expression in ovarian epithelial tumors: evaluation of their respective prognostic significance by multivariate analysis. Int J Cancer (1995) 0.90
Relative efficiencies of a series of square-planar plantinum(II) compounds on Salmonella mutagenesis. Mutat Res (1977) 0.90
Lack of single-strand DNA-binding protein amplification under conditions of SOS induction in E. coli. Mol Gen Genet (1983) 0.90
Ultrastructural alterations of Trypanosoma cruzi kinetoplast induced by the interaction of a trypanocidal drug (hydroxystilbamidine) with the kinetoplast DNA. J Ultrastruct Res (1971) 0.89
ATP-independent DNA topoisomerase II as potential drug target in trypanosomes. Biol Cell (1988) 0.89
In vivo stimulation by antitumor drugs of the topoisomerase II induced cleavage sites in c-myc protooncogene. Biochem Biophys Res Commun (1986) 0.89
Molecular organization of the kinetoplast DNA of Trypanosoma cruzi treated with berenil, a DNA interacting drug. J Ultrastruct Res (1972) 0.89
Voltage-dependent introduction of a d[alpha]octothymidylate into electropermeabilized cells. Biochem Biophys Res Commun (1989) 0.88
[DNA ultrastructure of the kinetoplast of Trypanosoma cruzi cultivated in vitro]. C R Acad Sci Hebd Seances Acad Sci D (1969) 0.88
[Presence of papillomavirus genomes and amplification of the c-myc and C-Ha-ras oncogenes in invasive cancers of the uterine cervix]. C R Acad Sci III (1984) 0.88
Circular oligomers in mitochondrial DNA of human and beef nonmalignant thyroid glands. Proc Natl Acad Sci U S A (1972) 0.88
[N-Methyl-9 hydroxy-ellipticine (NSC 264-137) in the treatment of malignant metastases. Preliminary results (author's transl)]. Nouv Presse Med (1981) 0.87
Alpha-anomeric DNA: beta-RNA hybrids as new synthetic inhibitors of Escherichia coli RNase H, Drosophila embryo RNase H and M-MLV reverse transcriptase. Gene (1988) 0.87
Synthesis, thermal stability and reactivity towards 9-aminoellipticine of double-stranded oligonucleotides containing a true abasic site. Nucleic Acids Res (1989) 0.87
Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation. Biochem Pharmacol (1993) 0.87
[Kinetic study of the replicative forms of DNA in animal cells]. Biochim Biophys Acta (1967) 0.87
A new DNA intercalating drug: Methoxy-9-ellipticine. FEBS Lett (1971) 0.86
Prognostic value of c-myc proto-oncogene overexpression in early invasive carcinoma of the cervix. J Clin Oncol (1990) 0.86
Structure and expression of c-myc and c-fos proto-oncogenes in thyroid carcinomas. Br J Cancer (1988) 0.86
Association of c-erbB2-gene amplification with poor prognosis in non-inflammatory breast carcinomas but not in carcinomas of the inflammatory type. Int J Cancer (1994) 0.85
A yeast mitochondrial deoxyribonuclease stimulated by ethidium bromide. Biochem Biophys Res Commun (1972) 0.85
Frameshift lesions induced by oxazolopyridocarbazoles are recognized by the mismatch repair system in Escherichia coli. Mutat Res (1988) 0.85
[Purification and properties of a snail (Helix pomatia L.) hepato-pancreas acid desoxyribonuclease]. C R Acad Sci Hebd Seances Acad Sci D (1966) 0.85
Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. J Med Chem (1981) 0.85
[Isolation and fractionation of yeast deoxyribonucleic acid (DNA)]. C R Acad Sci Hebd Seances Acad Sci D (1966) 0.85
N-myc genomic content and DNA ploidy in stage IVS neuroblastoma. J Clin Oncol (1991) 0.85
Study of molecular markers of resistance to m-AMSA in a human breast cancer cell line. Decrease of topoisomerase II and increase of both topoisomerase I and acidic glutathione S transferase. Biochem Pharmacol (1991) 0.84
Efficient breakage of DNA apurinic sites by the indoleamine related 9-amino-ellipticine. Chem Biol Interact (1986) 0.84
Nuclear and kinetoplastic DNA from trypanosomes. J Protozool (1969) 0.84
Analysis of topoisomerase II-mediated DNA cleavage of the c-myc gene during HL60 differentiation. FEBS Lett (1993) 0.84
A randomised 2 x 2 factorial design to evaluate different smoking cessation methods. Rev Epidemiol Sante Publique (1992) 0.84
Restriction cleavage map of kinetoplast DNA minicircles from Trypanosoma equiperdum. Biochem Biophys Res Commun (1979) 0.84
Different levels of induction of RecA protein in E. coli (PQ 10) after treatment with two related carcinogens. Nucleic Acids Res (1983) 0.84
[Ultrastructure of DNA alterations of Trypanosoma cruzi kinetoplasts treated with ethidium bromide]. C R Acad Sci Hebd Seances Acad Sci D (1969) 0.84
Expression of MDR1 and GST pi genes in 35 advanced neuroblastomas. Prog Clin Biol Res (1991) 0.84
[Mitochondrial DNA of malignant cells]. Bull Cancer (1971) 0.84
Stimulation of topoisomerase II-mediated DNA cleavage by ellipticine derivatives: structure-activity relationship. Mol Pharmacol (1992) 0.84
Interactions between ellipticine and some derivatives and phospholipids in model membranes. FEBS Lett (1979) 0.84
Stimulation of the topoisomerase II induced DNA cleavage sites in the c-myc protooncogene by antitumor drugs is associated with gene expression. Biochemistry (1989) 0.83
Topoisomerase II-mediated DNA cleavage activity induced by ellipticines on the human tumor cell line N417. Biochem Pharmacol (1989) 0.83