Published in Nature on June 27, 1970
SAP-controlled T-B cell interactions underlie germinal centre formation. Nature (2008) 5.14
Demonstration that antigen-binding cells are precursors of antibody-producing cells after purification with a fluorescence-activated cell sorter. Proc Natl Acad Sci U S A (1972) 3.77
Radioresistance of the enhancing effect of cells from carrier-immunized mice in an in vitro primary immune response. Proc Natl Acad Sci U S A (1971) 2.79
Lymphoid tissue architecture. Experimental analysis of the origin and distribution of T-cells and B-cells. Immunology (1972) 2.65
Cell cooperation in the immune response. Clin Exp Immunol (1971) 1.91
Studies on immunological paralysis. IX. The immunogenicity and tolerogenicity of levan (polyfructose) in mice. Immunology (1972) 1.84
Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation. J Immunol (2007) 1.63
Studies of peripheral blood T-and B-lymphocytes in acute infections. Infect Immun (1974) 1.58
Antibody formation by bone marrow cells in irradiated mice. I. Thymus-dependent and thymus-independent responses to sheep erythrocytes. Immunology (1971) 1.31
Effect of allogeneic cell interaction on the primary immune response in vitro. Cell types involved in suppression and stimulation of antibody synthesis. Clin Exp Immunol (1972) 1.27
A brief history of T cell help to B cells. Nat Rev Immunol (2015) 1.21
Cognate stimulatory B-cell-T-cell interactions are critical for T-cell help recruited by glycoconjugate vaccines. Infect Immun (1999) 1.15
Age-decrease of cells sensitive to an autoantibody-specific for thymocytes and thymus-dependent lymphocytes in NZB mice. Clin Exp Immunol (1972) 1.14
T and B lymphocytes in mice studied by using antisera against surface antigenic markers. Am J Pathol (1971) 1.09
Thymus dependence of the immune response: response to the haptenic determinant NIP in mice. Immunology (1971) 1.05
Role of antigenic structure in cell to cell cooperation. Proc Natl Acad Sci U S A (1976) 1.04
Non-specific factor replaces T cells in an IgG response to soluble antigens. Immunology (1977) 1.02
Cellular and humorial immune responses in mice. III. Acceleration of delayed hypersensitivity response by presensitization with suboptimal dose of antigen. Immunology (1976) 0.99
Effect of antibodies against immunoglobulins and the theta antigen on the specific and non-specific stimulation of mouse spleen cells in vitro. Immunology (1972) 0.98
Respiratory tract cell-mediated immunity: comparison of primary and secondary response. Infect Immun (1974) 0.95
Studies on B-cell memory. I. Generation and exhaustion of B-cell memory by thymus-dependent antigen in T-cell depleted mice. Immunology (1979) 0.93
Antibody production in mice. V. The suppressive effect of anti-carrier antibodies on cellular cooperation in the induction of secondary anti-hapten antibody responses. Immunology (1973) 0.92
Cellular and humoral immune responses in mice. II. Effect of intraperitoneal or subcutaneous injection of carrier of anti-hapten antibody and delayed hypersensitivity responses. Immunology (1975) 0.91
Structural control of immunogenicity. 3. Preparation for and elicitation of anamnestic antibody responses by oligo- and poly-lysines and their DNP derivatives. Immunology (1971) 0.90
Identification of derepressed autoimmunocompetent B lymphoid cells in NZB mice. Clin Exp Immunol (1974) 0.89
Rabbit anti-EL4 serum. A reagent with specificity for a population of murine suppressor cells. Immunology (1979) 0.86
Toward a molecular understanding of adaptive immunity: a chronology, part I. Front Immunol (2012) 0.84
Desmoglein 3-specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice. J Clin Invest (2011) 0.82
Response of mice to rabbit Fab' 2 and Fab'. Thymus independence of IgM response and thymus dependence of IgG response. Immunology (1972) 0.82
Expression of T cell suppressor activity in the immune response of newborn mice to a T-independent synthetic polypeptide. Immunology (1978) 0.81
Effect of tilorone on susceptibility of mice to primary or secondary infection with Listeria monocytogenes. Infect Immun (1976) 0.79
Characterization of immunogenic properties of haptenated liposomal model membranes in mice. IV. induction of IgM memory. Immunology (1981) 0.79
Antigen presentation as a factor in the protective immune response to renal infection. Clin Exp Immunol (1975) 0.78
T cell antigen discovery using soluble vaccinia proteome reveals recognition of antigens with both virion and nonvirion association. J Immunol (2014) 0.77
Carrier-specific recognition for induction of secretory IgA anamnestic antibody responses. Immunology (1987) 0.77
The histological response to a xenogeneic tumour in mice. Clin Exp Immunol (1973) 0.75
Defining cell-surface antigenic markers for mouse T and B cells. Front Immunol (2014) 0.75
Promotion of secondary anti-DNP antibody production in mice by type III pneumococcal polysaccharide (SIII) and dinitrophenylated rabbit antibody to SIII. Immunology (1975) 0.75
The lymphoid system and experimental neoplasias. J Clin Pathol Suppl (R Coll Pathol) (1974) 0.75
Internal histoincompatability during amphibian metamorphosis? Immunology (1981) 0.75
Programmed cell death in animal development. Cell (1997) 8.95
Immunoglobulin determinants on the surface of mouse lymphoid cells. Nature (1970) 8.35
Two distinct populations of peripheral lymphocytes in mice distinguishable by immunofluorescence. Immunology (1970) 7.10
A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature (1983) 6.52
Surface antigenic markers for distinguishing T and B lymphocytes in mice. Transplant Rev (1971) 6.38
An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism. Curr Biol (2001) 4.75
Cell death and control of cell survival in the oligodendrocyte lineage. Cell (1992) 4.70
Astrocytes induce blood-brain barrier properties in endothelial cells. Nature (1987) 4.70
Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve. Brain Res (1979) 4.39
All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody. Cell (1981) 4.28
Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA. Nature (1993) 4.00
Thymus dependence of theta-bearing cells in the peripheral lymphoid tissues of mice. Immunology (1970) 3.84
Normal distribution, patching and capping of lymphocyte surface immunoglobulin studied by electron microscopy. Nat New Biol (1973) 3.77
Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture. Brain Res (1979) 3.66
Early production of intracellular IgM by B-lymphocyte precursors in mouse. Nature (1976) 3.29
Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture. Nature (1978) 3.29
Molecular events during membrane fusion. A study of exocytosis in rat peritoneal mast cells. J Cell Biol (1977) 3.11
A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development. Development (1994) 2.83
Distribution of immunoglobulin on the surface of mouse lymphoid cells as determined by immunoferritin electron microscopy. Antibody-induced, temperature-dependent redistribution and its implications for membrane structure. Eur J Immunol (1972) 2.78
Programmed cell death and Bcl-2 protection in very low oxygen. Nature (1995) 2.76
Studies on the differentiation of thymus-derived lymphocytes. J Exp Med (1970) 2.56
Multiple extracellular signals are required for long-term oligodendrocyte survival. Development (1993) 2.55
Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO J (1994) 2.43
Differences in susceptibility of mature and immature mouse B lymphocytes to anti-immunoglobulin-induced immunoglobulin suppression in vitro. Possible implications for B-cell tolerance to self. J Exp Med (1975) 2.40
Mammalian plasma membranes. Nature (1975) 2.38
Clonal analysis of oligodendrocyte development in culture: evidence for a developmental clock that counts cell divisions. Cell (1986) 2.31
Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons. Nature (1993) 2.26
Extracellular control of cell size. Nat Cell Biol (2001) 2.23
Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics. J Neurosci (1983) 2.18
Ligand-induced redistribution of concanavalin A receptors on normal, trypsinized and transformed fibroblasts. Nat New Biol (1973) 2.18
Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death. J Cell Biol (1996) 2.17
Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development (1993) 2.07
Theta-bearing lymphocytes in nude mice. Nature (1973) 2.06
In vitro generation of B lymphocytes in mouse foetal liver, a mammalian 'bursa equivalent'. Nature (1974) 2.05
Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases. J Neurosci (2000) 2.04
Thymus-derived lymphocytes: their distribution and role in the development of peripheral lymphoid tissues of the mouse. Eur J Immunol (1971) 2.03
Myelin-specific proteins and glycolipids in rat Schwann cells and oligodendrocytes in culture. J Cell Biol (1980) 1.98
Axonal control of oligodendrocyte development. J Cell Biol (1999) 1.98
Accessory cell dependence of lectin-induced proliferation of mouse T lymphocytes. Eur J Immunol (1977) 1.95
Constitutive expression of the machinery for programmed cell death. J Cell Biol (1996) 1.88
Two glial cell lineages diverge prenatally in rat optic nerve. Dev Biol (1984) 1.85
Movement of lymphocyte surface antigens and receptors: the fluid nature of the lymphocyte plasma membrane and its immunological significance. Fed Proc (1973) 1.85
Direct demonstration of theta-positive antigen-binding cells, with antigen-induced movement of thymus-dependent cell receptors. J Exp Med (1973) 1.82
Induction of increased calcium uptake in mouse T lymphocytes by concanavalin A and its modulation by cyclic nucleotides. Nature (1975) 1.82
Glial cell diversification in the rat optic nerve. Science (1989) 1.82
Proliferating bipotential glial progenitor cells in adult rat optic nerve. Nature (1986) 1.76
Lack of replicative senescence in cultured rat oligodendrocyte precursor cells. Science (2001) 1.76
Retinal astrocytes are immigrants from the optic nerve. Nature (1988) 1.75
Monospecificity of bone marrow-derived lymphocytes. J Exp Med (1973) 1.74
Schwann cell growth factors. Cell (1978) 1.73
Astrocytes, ependymal cells, and oligodendrocytes develop on schedule in dissociated cell cultures of embryonic rat brain. Dev Biol (1981) 1.69
Control of oligodendrocyte number in the developing rat optic nerve. Neuron (1994) 1.68
A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve. Development (1999) 1.67
Cyclic AMP as a mitogenic signal for cultured rat Schwann cells. Nature (1978) 1.65
p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation. Curr Biol (1998) 1.61
T and B lymphocytes and immune responses. Nature (1973) 1.61
A crucial role for neurotrophin-3 in oligodendrocyte development. Nature (1994) 1.60
A quantitative immunohistochemical study of macroglial cell development in the rat optic nerve: in vivo evidence for two distinct astrocyte lineages. Dev Biol (1985) 1.59
A surface antigenic marker for rat Schwann cells. Nature (1977) 1.54
Studies on the generation of B lymphocytes in the mouse embryo. Eur J Immunol (1976) 1.51
Ischemic mononeuropathy multiplex associated with diabetes mellitus. Arch Neurol (1968) 1.50
Intravenous diazepam in the treatment of prolonged seizure activity. N Engl J Med (1967) 1.50
Cell type-specific markers for human glial and neuronal cells in culture. Lab Invest (1980) 1.49
A role for caspases in lens fiber differentiation. J Cell Biol (1998) 1.47
Rod photoreceptor development in vitro: intrinsic properties of proliferating neuroepithelial cells change as development proceeds in the rat retina. Neuron (1990) 1.45
Mouse specific bone marrow-derived lymphocyte antigen as a marker for thymus-independent lymphocytes. Nature (1971) 1.45
Redistribution and pinocytosis of lymphocyte surface immunoglobulin molecules induced by anti-immunoglobulin antibody. Nat New Biol (1971) 1.43
Is programmed cell death required for neural tube closure? Curr Biol (1997) 1.41
Long-term culture of purified postnatal oligodendrocyte precursor cells. Evidence for an intrinsic maturation program that plays out over months. J Cell Biol (2000) 1.40
Does oligodendrocyte survival depend on axons? Curr Biol (1993) 1.40
Differences between the clearance of apoptotic cells by professional and non-professional phagocytes. Curr Biol (2000) 1.39
Fibrous and protoplasmic astrocytes are biochemically and developmentally distinct. J Neurosci (1984) 1.38
Rat neural antigen-2 (RAN-2): a cell surface antigen on astrocytes, ependymal cells, Müller cells and lepto-meninges defined by a monoclonal antibody. Brain Res (1981) 1.38
Differentiation of a bipotential glial progenitor cell in a single cell microculture. Nature (1985) 1.37
Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture. Nature (1988) 1.34
The oligodendrocyte-type-2 astrocyte cell lineage is specialized for myelination. Nature (1986) 1.31
Ischemic mononeuropathy and mononeuropathy multiplex in diabetes mellitus. N Engl J Med (1968) 1.30
Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain. J Cell Biol (1991) 1.30
Caspase activation in the terminal differentiation of human epidermal keratinocytes. Curr Biol (1999) 1.30
Reconstitution of a developmental clock in vitro: a critical role for astrocytes in the timing of oligodendrocyte differentiation. Cell (1985) 1.30
Studies on the generation of B lymphocytes in fetal liver and bone marrow. J Immunol (1977) 1.29
Control of lens epithelial cell survival. J Cell Biol (1993) 1.24
Localized mast cell degranulation induced by concanavalin A-sepharose beads. Implications for the Ca2+ hypothesis of stimulus-secretion coupling. J Cell Biol (1978) 1.23
Glial cells are increased proportionally in transgenic optic nerves with increased numbers of axons. J Neurosci (1996) 1.22
PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (O-2A) cell lineage. Development (1989) 1.20
Cell death in the oligodendrocyte lineage. J Neurobiol (1992) 1.19
Tracing the development of oligodendrocytes from precursor cells using monoclonal antibodies, fluorescence-activated cell sorting, and cell culture. Dev Biol (1983) 1.18
The in vitro differentiation of a bipotential glial progenitor cell. EMBO J (1984) 1.16
Studies on cultured rat Schwann cells. III. Assays for peripheral myelin proteins. J Neurocytol (1980) 1.16
Type-2 astrocyte development in rat brain cultures is initiated by a CNTF-like protein produced by type-1 astrocytes. Neuron (1988) 1.13
Visualization of O-2A progenitor cells in developing and adult rat optic nerve by quisqualate-stimulated cobalt uptake. J Neurosci (1992) 1.12
Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells. Mol Biol Cell (1995) 1.10
Scrapie in immunologically deficient mice. Nature (1971) 1.10
PDGF and intracellular signaling in the timing of oligodendrocyte differentiation. J Cell Biol (1989) 1.10
The macroglial cells of the rat optic nerve. Annu Rev Neurosci (1989) 1.09
T and B lymphocytes in mice studied by using antisera against surface antigenic markers. Am J Pathol (1971) 1.09
Evidence that axon-derived neuregulin promotes oligodendrocyte survival in the developing rat optic nerve. Neuron (2000) 1.09
Differentiation signals in the CNS: type-2 astrocyte development in vitro as a model system. Neuron (1990) 1.08
Ultrastructural distribution and redistribution of alloantigens and concanavalin A receptors on the surface of mouse lymphocytes. Eur J Immunol (1974) 1.08
Evidence for large-scale astrocyte death in the developing cerebellum. J Neurosci (1995) 1.08