Published in Proc Natl Acad Sci U S A on April 01, 1971
Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. I. Characterization of the inhibitory cell activity. J Exp Med (1972) 3.80
The mechanism of antigenic stimulation of primary and secondary clonal precursor cells. J Exp Med (1972) 3.41
Cell interactions between histoincompatible T and B lymphocytes. I. Allogeneic effect by irradiated host T cells on adoptively transferred histoincompatible B lymphocytes. J Exp Med (1973) 2.49
Radioresistance of carrier-specific helper thymus-derived lymphocytes in mice. Proc Natl Acad Sci U S A (1972) 2.35
Biological expressions of lymphocyte activation : I. Effects of phytomitogens on antibody synthesis in vitro. J Exp Med (1973) 1.83
Functional characteristics of Peyer's patch lymphoid cells. I. Induction of humoral antibody and cell-mediated allograft reactions. J Exp Med (1974) 1.76
Immunoglobulins on the surface of thymus-derived cells engaged in the initiation of a humoral immune response. J Exp Med (1971) 1.73
Activation of antigen-specific B cells: role of T cells, cytokines, and antigen in induction of growth and differentiation. Proc Natl Acad Sci U S A (1983) 1.73
Mode of action of a supernatant activity from T-cell cultures that nonspecifically stimulates the humoral immune response. Proc Natl Acad Sci U S A (1974) 1.57
Regulation of the immune response. II. Qualitative and quantitative differences between thymus- and bone marrow-derived lymphocytes in the recognition of antigen. J Exp Med (1973) 1.57
Hapten-specific IgE antibody responses in mice. II. Cooperative interactions between adoptively transferred T and B lymphocytes in the development of IgE response. J Exp Med (1973) 1.55
Functional characteristics of Peyer's patch lymphoid cells. II. Lipopolysaccharide is thymus dependent. J Exp Med (1974) 1.37
T-cell regulation of T-cell responses to antigen. Immunology (1974) 1.37
Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J Exp Med (1971) 1.23
The radiosensitivity of T and B lymphocytes in mice. Immunology (1975) 1.18
Help and suppression by lymphoid cells as a function of cellular concentration. Proc Natl Acad Sci U S A (1979) 1.16
Cell-to-cell interaction in the immune response. 8. Radiosensitivity of thymus-derived lymphocytes. J Exp Med (1972) 1.16
Functional characteristics of Peyer's patch cells. III. Carrier priming of T cells by antigen feeding. J Exp Med (1975) 1.13
T cells cooperating in the induction of delayed-type hypersensitivity act via the linked recognition of antigenic determinants. J Exp Med (1982) 1.11
B-cell activation by lipopolysaccharide. Distinct pathways for induction of mitosis and antibody production. J Exp Med (1977) 1.11
Role of self-carriers in the immune response and tolerance. I. B-cell unresponsiveness and cytotoxic T-cell immunity induced by haptenated syngeneic lymphoid cells. J Exp Med (1976) 1.07
Generation of T-helper cells in vitro. I. Cellular and antigen requirements. J Exp Med (1977) 1.07
Relationships among differentiated T-cell subpopulations. III. Radioresistance of delayed hypersensitivity to heterologous erythrocytes. Immunology (1978) 1.03
Cross-reactions between erythrocytes at the T-cell level. Immunology (1973) 0.99
Cellular and humorial immune responses in mice. III. Acceleration of delayed hypersensitivity response by presensitization with suboptimal dose of antigen. Immunology (1976) 0.99
Reduced humoral immune activity in long-lived old mice: an approach to elucidating its mechanisms. Immunology (1976) 0.98
Phylogeny of lymphocyte heterogeneity: the cellular requirements for the mixed leucocyte reaction with channel catfish. Immunology (1986) 0.97
Antigen-induced human T cell help. Precursor frequency, radiation sensitivity, and allogeneic effects. J Clin Invest (1983) 0.95
Regulation of the immune response. 3. Kinetic differences between thymus- and bone marrow- derived lymphocytes in the proliferative response to heterologous erythrocytes. J Exp Med (1973) 0.95
Cellular and humoral immune responses in mice. II. Effect of intraperitoneal or subcutaneous injection of carrier of anti-hapten antibody and delayed hypersensitivity responses. Immunology (1975) 0.91
Relationships among differentiated T-cell subpopulations. V. T-cell dependent mechanism of xenograft rejection and its radioresistant nature. Immunology (1979) 0.86
Effect of X irradiation on homocytotropic and agglutinating antibody production in mice. Immunology (1977) 0.84
Studies on the immunopotentiating effects of a streptococcal preparation, OK-432. I. Enhancement of T cell-mediated immune responses of mice. Clin Exp Immunol (1979) 0.83
Helper T-cell kinetics and investigation of antigen receptor expression on early and memory T-helper cells. Immunology (1976) 0.80
Vitamin E and immune response. I. Enhancement of helper T cell activity by dietary supplementation of vitamin E in mice. Immunology (1979) 0.79
In vitro studies of 'antigenic competition'. II. Reconstitution of the immune defect and the relationship between antigen-induced suppression and non-specific enhancement. Immunology (1973) 0.78
Effect of pretreatment with immune serum on murine sarcoma virus (Moloney) tumour induction and growth. Br J Cancer (1977) 0.78
Direct cytotoxicity against chicken erythrocytes in mice. III. Degrees of radiosensitivity and cross-reactivity of cytotoxicity, delayed hypersensitivity and antibody production. Immunology (1979) 0.78
The goldfish immune response. I. Characterization of the humoral response to particulate antigens. Immunology (1981) 0.77
Effects of whole-body irradiation on antibody affinity. Immunology (1977) 0.75
Immunization of dissociated spleen cell cultures from normal mice. J Exp Med (1967) 30.93
Antitrinitrophenyl (TNP) plaque assay. Primary response of Balb/c mice to soluble and particulate immunogen. Proc Soc Exp Biol Med (1969) 18.89
Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes. J Exp Med (1968) 12.91
Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocytes. J Exp Med (1968) 9.67
Immunological activity of thymus and thoracic-duct lymphocytes. Proc Natl Acad Sci U S A (1968) 7.49
Carrier function in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization. J Exp Med (1970) 5.71
The requirement of more than one antigenic determinant for immunogenicity. J Exp Med (1969) 5.61
Cell to cell interaction in the immune response. 3. Chromosomal marker analysis of single antibody-forming cells in reconstituted, irradiated, or thymectomized mice. J Exp Med (1968) 5.02
Immunocompetence of transferred thymus-marrow cell combinations. J Immunol (1966) 4.52
An in vitro primary immune response to 2,4,6-trinitrophenyl substituted erythrocytes: response against carrier and hapten. J Immunol (1970) 3.63
The role of nonlymphoid accessory cells in the immune response to different antigens. J Exp Med (1970) 2.82
Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing anti-hapten antibody responses. J Exp Med (1970) 2.54
Role of thymus-derived lymphocytes in the secondary humoral immune response in mice. Nature (1970) 2.53
Radioresistance of cooperative function of carrier-specific lymphocytes in antihapten antibody responses. Science (1970) 2.03
Cell components in the immune response. II. Cell attachment separation of immune cells. Cell Immunol (1970) 1.94
Distinct events in the immune response elicited by transferred marrow and thymus cells. I. Antigen requirements and priferation of thymic antigen-reactive cells. J Exp Med (1969) 1.72
Cell components in the immune response. 3. Neonatal thymectomy: restoration in culture. Cell Immunol (1970) 1.66
X-ray resistant cell required for the induction of in vitro antibody formation. Science (1969) 1.63
Density distribution analysis of antigen sensitive cells in the rat. Nature (1967) 1.42
Cell components in the immune response. IV. Relationships and possible interactions. Cell Immunol (1970) 1.36
Cell interaction in antibody synthesis. J Allergy (1969) 1.28
Cell components in the immune response. I. Gradient separation of immune cells. Cell Immunol (1970) 0.93
Induction in vitro of hapten specific plaque forming cells. Nature (1970) 0.92
Immunization of dissociated spleen cell cultures from normal mice. J Exp Med (1967) 30.93
Immunization of normal mouse spleen cell suspensions in vitro. Science (1966) 6.47
Cell populations and cell proliferation in the in vitro response of normal mouse spleen to heterologous erythrocytes. Analysis by the hot pulse technique. J Exp Med (1967) 5.78
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. I. Characterization of the inhibitory cell activity. J Exp Med (1972) 3.80
Activated antigen-specific CD8+ T cells persist in the lungs following recovery from respiratory virus infections. J Immunol (2001) 3.68
An in vitro primary immune response to 2,4,6-trinitrophenyl substituted erythrocytes: response against carrier and hapten. J Immunol (1970) 3.63
Culture supernatants of a stimulated T-cell line have helper activity that acts synergistically with interleukin 2 in the response of B cells to antigen. Proc Natl Acad Sci U S A (1981) 3.28
Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev (1991) 3.21
Cellular events in the immune response : analysis and in vitro response of mouse spleen cell populations separated by differential flotation in albumin gradients. J Exp Med (1968) 3.12
Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med (1994) 3.02
Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis. J Exp Med (1997) 2.59
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56
Delayed hypersensitivity: is the same population of thymus-derived cells responsible for cellular immunity reactions and the carrier effect? Immunol Commun (1972) 2.42
Immune response restoration with macrophage culture supernatants. Science (1971) 2.37
Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. II. Evidence for separate stimulatory and inhibitory cells. J Exp Med (1973) 2.33
Separate signals for the initiation of proliferation and differentiation in the b cell response to antigen. Transplant Rev (1975) 2.32
Suppressor T cells. Transplant Rev (1975) 2.28
Production of a B cell growth-promoting activity, (DL)BCGF, from a cloned T cell line and its assay on the BCL1 B cell tumor. J Exp Med (1982) 2.22
Differential stimulation of precursor cells and carrier-specific thymus-derived cell activity in the in vivo reponse to heterologous erythrocytes in mice. J Immunol (1972) 2.21
Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection. J Exp Med (1999) 2.09
Naive, effector, and memory CD8 T cells in protection against pulmonary influenza virus infection: homing properties rather than initial frequencies are crucial. J Immunol (1999) 1.99
Cell components in the immune response. II. Cell attachment separation of immune cells. Cell Immunol (1970) 1.94
Inhibition of spleen cell DNA synthesis by autologous macrophages. J Immunol (1966) 1.84
Immunoglobulins on the surface of thymus-derived cells engaged in the initiation of a humoral immune response. J Exp Med (1971) 1.73
Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line. J Immunol (1981) 1.73
The Lyt phenotype of a long-term allospecific T cell line. Both helper and killer activities to IA are mediated by Ly-1 cells. Eur J Immunol (1981) 1.72
Radioresistance of cells responsible for delayed hypersensitivity reactions in the mouse. J Immunol (1975) 1.72
Cell components in the immune response. 3. Neonatal thymectomy: restoration in culture. Cell Immunol (1970) 1.66
Further studies of the stimulation of DNA synthesis in cultures of spleen cell suspensions by homologous cells in inbred strains of mice and rats. J Exp Med (1965) 1.63
Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology. Am J Pathol (2001) 1.63
Type 1 and type 2: a fundamental dichotomy for all T-cell subsets. Curr Opin Immunol (1996) 1.60
Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibility complex-restricted responses. J Exp Med (1983) 1.56
Continuously proliferating allospecific T cells. I. Specificity of cooperation with allogeneic B cells in the humoral antibody response to sheep erythrocytes. J Exp Med (1979) 1.54
Localization of antigenic determinants in the polypeptide chains of collagen. Science (1969) 1.51
Antigen receptor molecules: inhibition by antiserum against kappa light chains. Science (1970) 1.46
The significance of T-B collaboration across haplotype barriers. Cold Spring Harb Symp Quant Biol (1977) 1.44
The role of IL4 and IL5: characterization of a distinct helper T cell subset that makes IL4 and IL5 (Th2) and requires priming before induction of lymphokine secretion. Immunol Rev (1988) 1.44
T cell replacing factors in the B cell response to antigen. Immunol Rev (1982) 1.44
In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines. J Immunol (1998) 1.43
Spleen cell proliferation in response to homologous antigens studied in congenic resistant strains of mice. J Exp Med (1966) 1.39
Separation of helper and suppressor T lymphocytes. II. Ly phenotypes and lack of DNA synthesis requirement for the generation of concanavalin A helper and suppressor cells. J Exp Med (1977) 1.39
Separation of helper and suppressor T lymphocytes on a ficoll velocity sedimentation gradient. J Exp Med (1976) 1.36
Cell components in the immune response. IV. Relationships and possible interactions. Cell Immunol (1970) 1.36
Symposium on in vitro studies of the immune response. II. Significance of the reaction of lymphoid cells to homologous tissue. Bacteriol Rev (1966) 1.36
Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response. J Immunol (1977) 1.30
The properties of plaque-forming cells from autoimmune and normal strains of mice with specificity for autologous erythrocyte antigens. J Immunol (1975) 1.25
Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J Exp Med (1971) 1.23
Production of Con A-induced helper T cell replacing factor requires a T cell and an Ia-positive non-T cells. J Immunol (1980) 1.23
In vitro studies of immunological responses of lymphoid cells. Adv Immunol (1967) 1.20
Stimulation of DNA synthesis in cultures of mouse spleen cell suspensions by bovine transferrin. Exp Cell Res (1969) 1.18
B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. J Exp Med (1987) 1.17
Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection. J Exp Med (1980) 1.14
Partial purification and characterization of a BCGFII from EL4 culture supernatants. J Immunol (1984) 1.13
Alloantigen-induced T helper activity. I. Minimal genetic differences necessary to induce a positive allogeneic effect. J Immunol (1978) 1.10
Ly phenotypes and MHC recognition: the allohelper that recognizes K or D is a mature Ly123 cell. J Immunol (1979) 1.06
Fine specificity mapping of two allospecific T cell lines: recognition of private specificities in the H-2 IA subregion. Eur J Immunol (1981) 1.04
Therapeutic effects of tumor-reactive type 1 and type 2 CD8+ T cell subpopulations in established pulmonary metastases. J Immunol (1999) 1.03
Competition between concanavalin A-induced stimulatory and inhibitory effects in the in vitro immune response to antigen. J Exp Med (1975) 1.02
Role of effector cell-derived IL-4, IL-5, and perforin in early and late stages of type 2 CD8 effector cell-mediated tumor rejection. J Immunol (2001) 1.01
Antibody synthesis in vitro, a marker of B cell differentiation. J Immunol Methods (1980) 0.99
Evidence that Con A induces cytotoxicity in the same subclass of T cells as does alloimmunization. J Immunol (1977) 0.98
In vitro induction of specific unresponsiveness against the 2,4,6-trinitrophenyl determinant. I. The induction of unresponsiveness. J Immunol (1974) 0.98
Evidence for two distinct activation states available to B lymphocytes. J Immunol (1984) 0.98
Improving geometric model construction for blood flow modeling. IEEE Eng Med Biol Mag (1999) 0.97
Toward an objective classification of cells in the immune system. Proc Natl Acad Sci U S A (1988) 0.96
Regulation of the immune response T-cell interactions. CRC Crit Rev Immunol (1982) 0.96
CD28, IL-2-independent costimulatory pathways for CD8 T lymphocyte activation. J Immunol (1999) 0.96
Alloreactivity, the development of the T cell repertoire and the understanding of T cell function. Immunol Rev (1978) 0.95
Cellular cooperation in hapten-carrier responses in the newt, Triturus viridescens. Cell Immunol (1973) 0.94
Relative perforin- and Fas-mediated lysis in T1 and T2 CD8 effector populations. J Immunol (1995) 0.93
Cell components in the immune response. I. Gradient separation of immune cells. Cell Immunol (1970) 0.93
The humoral response of mouse spleen cells to two types of sheep erythrocytes. I. Genetic control of the response to H and L SRBC. J Immunol (1975) 0.91
Immunopotentiating role of IFN-gamma in early and late stages of type 1 CD8 effector cell-mediated tumor rejection. Clin Immunol (2001) 0.91
The humoral response of mouse spleen cells to two types of sheep erythrocytes. III. A new VH region marker. J Immunol (1975) 0.91
The structure of the mouse immunoglobulin in gamma 3 membrane gene segment. Nucleic Acids Res (1983) 0.90
Purification and partial sequence analysis of murine B cell growth factor II (interleukin 5). J Immunol (1987) 0.90
Negative allogeneic effects in vitro. II. Mapping of histocompatibility differences leading to allosuppression. J Immunol (1977) 0.89
A monoclonal T cell-replacing activity can act directly on B cells to enhance clonal expansion. J Exp Med (1982) 0.89
An attempt to assess the overall diversity of murine T cells using two-dimensional gel electrophoresis. Eur J Immunol (1984) 0.89
Consequences of the direct interaction of helper T cells with B cells presenting antigen. Immunol Rev (1987) 0.89
Hapten-specific tolerance in mice. II. Adoptive transfer studies and evidence for unresponsiveness in the B cells. Eur J Immunol (1974) 0.89
Changes in the protein pattern of murine B cells after mitogenic stimulation. Eur J Immunol (1984) 0.88
Type 1 and type 2 CD8+ effector T cell subpopulations promote long-term tumor immunity and protection to progressively growing tumor. J Immunol (2000) 0.88
Frequency of allogeneic helper T cells responding to whole H-2 differences and to an H-2K difference alone. J Immunol (1979) 0.87
An approach to molecular analysis of T-cell clones by two-dimensional gel electrophoresis: is there interclonal and intraclonal heterogeneity? Clin Chem (1984) 0.86
Role of antigen in the B cell response. Specific antigen and the lymphokine IL-5 synergize to drive B cell lymphoma proliferation and differentiation to Ig secretion. J Immunol (1988) 0.86
Antigen suppression of the in vitro development of plaque-forming cells to autologous erythrocyte antigens. J Immunol (1975) 0.86
Characterization of the target antigen of F1 anti-parent cytotoxic lympholysis: analysis of the spontaneous in vitro F1 cytotoxic T lymphocytes. J Immunol (1980) 0.85
Induction of the H-2 D antigen during B cell activation. J Immunol (1989) 0.84
Precursor cell division during the immune response in vitro: antigen-induced and "spontaneous" antibody-forming cells. Eur J Immunol (1973) 0.84
Suppressor T cells in the regulation of the immune response. J Reticuloendothel Soc (1975) 0.83
Primary in vitro cytotoxic response of F1 T lymphocytes against parental antigens. J Immunol (1979) 0.82
Separation of helper and suppressor T lymphocytes. III. Positive and negative effects of mixed lymphocyte reaction-activated T cells. J Immunol (1978) 0.82
Independent analysis of T helper and T killer cell function in young and old NZB mice. J Immunol (1978) 0.82
The allogeneic effect: bystander effect in the primary immune response in vitro. Eur J Immunol (1974) 0.81
Monoclonal antibody that distinguishes between a phosphorylated, beta 2-microglobulin-associated, and a free, nonphosphorylated, chain of MHC class I. J Immunol (1993) 0.81