Published in Proc Natl Acad Sci U S A on June 01, 1970
Purification and properties of biologically active messenger RNA for a myeloma light chain. Proc Natl Acad Sci U S A (1972) 5.28
Plasma cell immunoglobulin secretion: arrest is accompanied by alterations of the golgi complex. J Exp Med (1977) 4.59
Biologically and chemically pure mRNA coding for a mouse immunoglobulin L-chain prepared with the aid of antibodies and immobilized oligothymidine. Proc Natl Acad Sci U S A (1973) 4.02
Purification of 14S messenger RNA of immunoglobulin light chain that codes for a possible light-chain precursor. Proc Natl Acad Sci U S A (1973) 3.25
Unreleased intracellular monoclonal macroglobulin in chronic lymphocytic leukaemia. Clin Exp Immunol (1972) 1.57
Immunoglobulin synthesis and secretion. VI. Synthesis and intracellular transport of immunoglobulin in nonsecretory lymphoma cells. J Exp Med (1971) 1.45
Immunoglobulin synthesis and secretion. V. Incorporation of leucine and glucosamine into immunoglobulin on free and bound polyribosomes. Proc Natl Acad Sci U S A (1970) 1.36
Membrane-bound ribosomes of myeloma cells. IV. mRNA complexity of free and membrane-bound polysomes. J Cell Biol (1981) 1.33
Virus-specific messenger RNA and nascent polypeptides in polyribosomes of cells replicating murine sarcoma-leukemia viruses. Proc Natl Acad Sci U S A (1973) 1.30
Membrane-bound ribosomes of myeloma cells. I. Preparation of free and membrane-bound ribosomal fractions. Assessment of the methods and properties of the ribosomes. J Cell Biol (1975) 1.19
Studies on the intracellular segregation of polyribosome-associated messenger ribonucleic acid species in the lactating guinea-pig mammary gland. Biochem J (1979) 1.19
Insulin biosynthesis: studies of Islet polyribosomes (nascent peptides-sucrose gradient analysis-gel filtration). Proc Natl Acad Sci U S A (1972) 0.94
The selectivity and stoicheiometry of membrane binding sites for polyribosomes, ribosomes and ribosomal subunits in vitro. Biochem J (1975) 0.93
Role of membrane-bound and free polyribosomes in the synthesis of cytochrome c in rat liver. Biochem J (1974) 0.83
A cytochemical study on the pancreas of the guinea pig. 5. In vivo incorporation of leucine-1-C14 into the chymotrypsinogen of various cell fractions. J Biophys Biochem Cytol (1960) 5.83
Controlled proteolysis of nascent polypeptides in rat liver cell fractions. II. Location of the polypeptides in rough microsomes. J Cell Biol (1970) 5.72
Vectorial discharge of peptides released by puromycin from attached ribosomes. Proc Natl Acad Sci U S A (1966) 5.69
Biosynthesis of serum proteins and ferritin by free and attached ribosomes of rat liver. J Biol Chem (1969) 3.66
Preferential synthesis of ferritin and albumin by different populations of liver polysomes. Science (1969) 2.89
Ribosomes in rat liver: an estimate of the percentage of free and membrane-bound ribosomes interacting with messenger RNA in vivo. J Mol Biol (1967) 2.33
Isolation and properties of polyribosomes and fragments of the endoplasmic reticulum from rat liver. Biochem J (1967) 2.13
Free and membrane-bound ribosomes in rat liver. J Biol Chem (1967) 1.62
HERITABLE VARIATION IN BENCE JONES PROTEIN STRUCTURE IN AN INBRED STRAIN OF MICE. J Mol Biol (1964) 1.54
Studies on cell-free synthesis of rat immunoglobulins, II. Synthesis of immunoglobulin and of antibody to the dinitrophenyl hapten. Proc Natl Acad Sci U S A (1967) 1.32
Chemical identification of specific immunoglobulins as the product of a cell-free system from plasmocytoma tumors. Proc Natl Acad Sci U S A (1968) 1.01
Studies on cell-free synthesis of rat immunoglobulins, I. A cell-free system for protein synthesis prepared from lymph-node microsomal vesicles. Proc Natl Acad Sci U S A (1967) 0.97
Comparison of guinea pig gamma 1-and gamma 2-immunoglobulins by peptide mapping. Biochemistry (1967) 0.86
The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell (1989) 10.98
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science (1987) 7.01
Tumor necrosis factor and disease severity in children with falciparum malaria. N Engl J Med (1989) 6.79
Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors. J Exp Med (1986) 5.09
Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B. Mol Cell Biol (1990) 5.08
Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J Exp Med (1990) 4.90
The gut-associated lymphoid system: nature and properties of the large dividing cells. Eur J Immunol (1974) 4.76
Plasma cell immunoglobulin secretion: arrest is accompanied by alterations of the golgi complex. J Exp Med (1977) 4.59
The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions. J Exp Med (1978) 4.57
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc Natl Acad Sci U S A (1995) 4.28
Improved complementation in the cytotoxic test. Transplantation (1970) 3.93
Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J Exp Med (1991) 3.63
Comparative studies of intracellular transport of secretory proteins. J Cell Biol (1978) 3.62
Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease. J Exp Med (1987) 3.62
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med (1989) 3.58
Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature (1990) 3.46
Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation. Cell (1987) 3.46
Organ and isotype distribution of plasma cells producing specific antibody after oral immunization: evidence for a generalized secretory immune system. J Immunol (1979) 3.37
Human smooth muscle autoantibody. Its identification as antiactin antibody and a study of its binding to "nonmuscular" cells. Am J Pathol (1973) 3.36
Cell surface immunoglobulin. XI. The appearance of an IgD-like molecule on murine lymphoid cells during ontogeny. J Exp Med (1975) 3.26
Purification of 14S messenger RNA of immunoglobulin light chain that codes for a possible light-chain precursor. Proc Natl Acad Sci U S A (1973) 3.25
The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells. Cell (2000) 3.19
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc Natl Acad Sci U S A (1989) 3.03
Mouse thymus-independent and thymus-derived lymphoid cells. I. Immunofluorescent and functional studies. J Exp Med (1972) 2.96
In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices. J Cell Biol (1983) 2.91
The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation. J Exp Med (1991) 2.82
L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J Immunol (1986) 2.79
The distribution of large dividing lymph node cells in syngeneic recipient rats after intravenous injection. J Exp Med (1969) 2.76
An immunofluorescent study of pathogenic mechanisms in glomerular diseases. N Engl J Med (1966) 2.70
The distribution of antigenic and nonantigenic compounds within draining lymph nodes. Lab Invest (1966) 2.49
Gut injury in mouse graft-versus-host reaction. Study of its occurrence and mechanisms. J Clin Invest (1986) 2.47
Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus. Proc Natl Acad Sci U S A (1981) 2.45
Cellular aspects of immunoglobulin A. Adv Immunol (1976) 2.44
Plasma cell immunoglobulin M molecules. Their biosynthesis, assembly, and intracellular transport. J Cell Biol (1979) 2.29
The extrathymic T-cell development pathway. Immunol Today (1992) 2.27
Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions. J Exp Med (1991) 2.24
Charge of circulating immune complexes as a factor in glomerular basement membrane localization in mice. J Clin Invest (1981) 2.24
Intracellular neutralization of virus by immunoglobulin A antibodies. Proc Natl Acad Sci U S A (1992) 2.24
Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunol Rev (1989) 2.22
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis. J Clin Invest (1995) 2.20
Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes. Nature (1977) 2.10
The polymeric immunoglobulin receptor (secretory component) mediates transport of immune complexes across epithelial cells: a local defense function for IgA. Proc Natl Acad Sci U S A (1991) 2.02
Polypeptide chain structure of rabbit immunoglobulins. I. gamma-G-immunoglobulin. Biochemistry (1966) 2.00
Localization of free and bound secretory component in human intestinal epithelial cells. A model for the assembly of secretory IgA. J Exp Med (1974) 1.91
Thymus-independent (B) cell proliferation in spleen cell cultures of mouse radiation chimeras stimulated by phytohemagglutinin or allogeneic cells. J Exp Med (1972) 1.90
An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis. EMBO J (1997) 1.90
Combined oral/nasal immunization protects mice from Sendai virus infection. J Immunol (1987) 1.90
A three-tiered view of the role of IgA in mucosal defense. Immunol Today (1993) 1.84
Characteristics of mesenteric lymph node cells homing to gut-associated lymphoid tissue in syngeneic mice. J Immunol (1975) 1.84
Polypeptide chain structure of rabbit immunoglobulins. II. gamma-M-immunoglobulin. Biochemistry (1966) 1.84
Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency. J Clin Invest (1997) 1.81
Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice. J Exp Med (1994) 1.79
Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality. Eur J Immunol (1991) 1.78
Specificity of the antibodies produced by single cells following immunization with antigens bearing two types of antigenic determinants. J Exp Med (1967) 1.75
Lectin-binding sites as markers of Golgi subcompartments: proximal-to-distal maturation of oligosaccharides. J Cell Biol (1983) 1.74
Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3. Proc Natl Acad Sci U S A (1986) 1.73
Origin of IgA-secreting plasma cells in the mammary gland. J Exp Med (1977) 1.71
Cell surface immunoglobulin. X. Identification of an IgD-like molecule on the surface of murine splenocytes. J Exp Med (1974) 1.70
Absence of filipin-sterol complexes from large coated pits on the surface of culture cells. Proc Natl Acad Sci U S A (1979) 1.67
Mouse bone marrow lymphocytes and their differentiation. J Immunol (1974) 1.66
Small bowel enteropathy: role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-gamma, TNF) in the induction of epithelial cell death and renewal. Eur J Immunol (1998) 1.64
Mesenteric lymph node B lymphoblasts which home to the small intestine are precommitted to IgA synthesis. J Exp Med (1977) 1.63
Modulation of TL (thymus-leukemia) antigens by Fab-fragments of TL antibody. J Immunol (1968) 1.62
Gut mucosal mast cells. Origin, traffic, and differentiation. J Exp Med (1984) 1.61
Oral administration of cholera toxin-Sendai virus conjugate potentiates gut and respiratory immunity against Sendai virus. J Immunol (1988) 1.60
Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death. J Exp Med (1996) 1.56
Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis. Am J Pathol (1990) 1.53
Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia. J Exp Med (1990) 1.48
Mouse vaginal opening is an apoptosis-dependent process which can be prevented by the overexpression of Bcl2. Dev Biol (1997) 1.47
A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection. J Exp Med (1996) 1.46
Immunoglobulin-bearing and complement-receptor lymphocytes constitute the same population in human peripheral blood. J Clin Invest (1976) 1.46
Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis. Eur J Immunol (1987) 1.46
Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med (1992) 1.46
Human endothelial cell cultures: phenotypic modulation by leukocyte interleukins. J Cell Physiol (1985) 1.45
Unstable inter-H chain disulfide bonding and non-covalently associated J chain in rat dimeric IgA. Mol Immunol (1993) 1.45
Experimental IgA nephropathy induced by oral immunization. J Exp Med (1983) 1.45
Immunoglobulin A monoclonal antibodies protect against Sendai virus. J Virol (1987) 1.44
Mouse thymus-independent and thymus-derived lymphoid cells. II. Ultrastructural studies. J Exp Med (1972) 1.43
Presence of two types of L polypeptide chains in guinea pig 7S immunoglobulins. J Exp Med (1966) 1.43
Late administration of monoclonal antibody to leukocyte function-antigen 1 abrogates incipient murine cerebral malaria. Eur J Immunol (1991) 1.42
IgA nephropathy: pathogenesis of the most common form of glomerulonephritis. Lab Invest (1989) 1.41
Activation of the guinea pig alternative complement pathway by mouse IgA immune complexes. J Exp Med (1982) 1.39
Inhibition of microbial IgA proteases by human secretory IgA and serum. Mol Immunol (1983) 1.38
Identical T cell clones are located within the mouse gut epithelium and lamina propia and circulate in the thoracic duct lymph. J Exp Med (2000) 1.38
Modulations of functional activity in differentiated macrophages are accompanied by early and transient increase or decrease in c-fos gene transcription. J Immunol (1987) 1.38
Functional analysis of T cell subsets from mice bearing the lpr gene. J Immunol (1985) 1.38
Oligoclonal repertoire of the CD8 alpha alpha and the CD8 alpha beta TCR-alpha/beta murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells. J Exp Med (1994) 1.36
The pathogenetic role of the coagulation process in glomerular diseases of immunologic origin. Adv Nephrol Necker Hosp (1971) 1.34
Intracellular transport of lymphoid surface glycoproteins. Role of the Golgi complex. J Mol Biol (1981) 1.34
Studies on cell-free synthesis of rat immunoglobulins, II. Synthesis of immunoglobulin and of antibody to the dinitrophenyl hapten. Proc Natl Acad Sci U S A (1967) 1.32
Protein disulphide-isomerase from human placenta and rat liver. Purification and immunological characterization with monoclonal antibodies. Biochem J (1987) 1.31