Published in C R Acad Sci Hebd Seances Acad Sci D on March 04, 1974
A new antitumoral agent: 9-hydroxyellipticine. Possibility of a rational design of anticancerous drugs in the series of DNA intercalating drugs. Proc Natl Acad Sci U S A (1974) 1.18
A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization. J Mol Biol (1967) 10.36
A new fluorometric method for RNA and DNA determination. Anal Biochem (1966) 6.74
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature (1995) 6.72
ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett (1994) 3.78
cis elements and trans-acting factors involved in dimer formation of murine leukemia virus RNA. J Virol (1990) 3.40
Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses. Eur J Cancer (1991) 2.79
Characterization of a new class of circular DNA molecules in yeast. Biochem Biophys Res Commun (1971) 2.33
alpha-DNA II. Synthesis of unnatural alpha-anomeric oligodeoxyribonucleotides containing the four usual bases and study of their substrate activities for nucleases. Nucleic Acids Res (1987) 2.06
Transient electropermeabilization of cells in culture. Increase of the cytotoxicity of anticancer drugs. Biochem Pharmacol (1988) 1.91
gamma-Tubulin participates in the formation of the midbody during cytokinesis in mammalian cells. J Cell Sci (1993) 1.71
Recruitment of antigenic gamma-tubulin during mitosis in animal cells: presence of gamma-tubulin in the mitotic spindle. J Cell Sci (1994) 1.69
Control of UV induction of recA protein. Proc Natl Acad Sci U S A (1983) 1.68
An analytical study of the dimerization of in vitro generated RNA of Moloney murine leukemia virus MoMuLV. Nucleic Acids Res (1990) 1.62
In vivo electrically mediated protein and gene transfer in murine melanoma. Nat Biotechnol (1998) 1.58
Introduction of definite amounts of nonpermeant molecules into living cells after electropermeabilization: direct access to the cytosol. Exp Cell Res (1988) 1.57
alpha-DNA. VI: Comparative study of alpha- and beta-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition. Nucleic Acids Res (1987) 1.53
[Electrochemotherapy, a new antitumor treatment: first clinical trial]. C R Acad Sci III (1991) 1.52
Human 76p: A new member of the gamma-tubulin-associated protein family. J Cell Biol (1999) 1.44
Preparation and properties of nuclear and satellite deoxyribonucleic acid of Trypanosoma cruzi. J Mol Biol (1967) 1.31
Electrochemotherapy of spontaneous mammary tumours in mice. Eur J Cancer (1991) 1.26
The use of ethidium bromide-circular DNA complexes for the fluorometric analysis of breakage and joining of DNA. J Mol Biol (1971) 1.23
Smoking cessation rates 4 years after treatment by nicotine gum and acupuncture. Prev Med (1997) 1.22
Purification and characterization of recA protein from salmonella typhimurium. J Biol Chem (1983) 1.20
A new antitumoral agent: 9-hydroxyellipticine. Possibility of a rational design of anticancerous drugs in the series of DNA intercalating drugs. Proc Natl Acad Sci U S A (1974) 1.18
[Interaction of ethidium hydrobromate (EH) with polyribonucleotides. Applications to the study of hybridization reactions]. C R Acad Sci Hebd Seances Acad Sci D (1965) 1.15
[Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 is an agonist of the nociceptin (ORL1) receptor. Eur J Pharmacol (1998) 1.07
Initial degradation of deoxyribonucleic acid after injection in mammals. Cancer Res (1965) 1.06
Comparative activity of alpha- and beta-anomeric oligonucleotides on rabbit beta globin synthesis: inhibitory effect of cap targeted alpha-oligonucleotides. Biochem Biophys Res Commun (1989) 1.05
Platinum and palladium complexes of 3-methyl orotic acid: a route toward palladium complexes with good antitumor activity. J Inorg Biochem (1990) 1.05
Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids. Eur J Pharmacol (1997) 1.05
A protein inhibitor of acid deoxyribonucleases. Proc Natl Acad Sci U S A (1969) 1.03
VanA-type enterococci from humans, animals, and food: species distribution, population structure, Tn1546 typing and location, and virulence determinants. Appl Environ Microbiol (2007) 1.03
Quadruplex-based molecular beacons as tunable DNA probes. J Am Chem Soc (2006) 1.02
Survival curve of a human melanoma in nude mice. J Natl Cancer Inst (1977) 1.01
Selective adhesion, lipid exchange and membrane-fusion processes between vesicles of various sizes bearing complementary molecular recognition groups. Chemphyschem (2001) 1.01
Managing type 2 diabetes in France: the ECODIA survey. Diabetes Metab (2000) 1.00
[Fractionation and characterization of desoxyribonucleic acid (DNA) of trypanosomes (Trypanosoma equiperdum)]. C R Acad Sci Hebd Seances Acad Sci D (1966) 1.00
Na+ ions and Gpp(NH)p selectively inhibit agonist interactions at mu- and kappa-opioid receptor sites in rabbit and guinea-pig cerebellum membranes. Eur J Pharmacol (1985) 0.98
The mammalian interphase centrosome: two independent units maintained together by the dynamics of the microtubule cytoskeleton. Eur J Cell Biol (1999) 0.98
Alpha-DNA VIII: thermodynamic parameters of complexes formed between the oligo-alpha-deoxynucleotides: alpha-d(GGAAGG) and alpha-d(CCTTCC) and their complementary oligo-beta-deoxynucleotides: beta-d(CCTTCC) and beta-d(GGAAGG) are different. Nucleic Acids Res (1989) 0.96
Fluorescent thermometers for dual-emission-wavelength measurements: molecular engineering and application to thermal imaging in a microsystem. Anal Chem (2009) 0.96
Alpha-DNA. IV: Alpha-anomeric and beta-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physicochemical properties and poly (rA) binding. Nucleic Acids Res (1987) 0.96
Multiple opiate binding sites in the central nervous system of the rabbit. Large predominance of a mu subtype in the cerebellum and characterization of a kappa subtype in the thalamus. Mol Pharmacol (1983) 0.96
Antitumor activity, pharmacology, and toxicity of ellipticines, ellipticinium, and 9-hydroxy derivatives: preliminary clinical trials of 2-methyl-9-hydroxy ellipticinium (NSC 264-137). Recent Results Cancer Res (1980) 0.94
Potential antitumor agents: synthesis and biological properties of aliphatic amino acid 9-hydroxyellipticinium derivatives. J Med Chem (1984) 0.93
Cost-effectiveness modeling of intrathecal baclofen therapy versus other interventions for disabling spasticity. Neurorehabil Neural Repair (2009) 0.93
Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative. Nucleic Acids Res (1991) 0.92
Circulating tumour cells: insights into tumour heterogeneity. J Intern Med (2013) 0.91
Synthesis, antitumor evaluation and SAR of new 1H-pyrrolo [3,2-c] quinoline-6,9-diones and 11H-indolo [3,2-c] quinoline-1,4-diones. Anticancer Drug Des (1994) 0.91
Ellipticine and derivatives induce breakage of L1210 cells DNA in vitro. Biochem Pharmacol (1979) 0.91
An immunoradiometric quantitative assay of Escherichia coli recA protein. Biochimie (1982) 0.91
Catalytic action of fuculose 1-phosphate aldolase (class II) as derived from structure-directed mutagenesis. Biochemistry (2000) 0.91
[3H]Tyr-D-Ser-Gly-Phe-Leu-Thr: a specific probe for the delta-opiate receptor subtype in brain membranes. Eur J Pharmacol (1982) 0.90
Relative efficiencies of a series of square-planar plantinum(II) compounds on Salmonella mutagenesis. Mutat Res (1977) 0.90
Distinct mechanisms for activation of the opioid receptor-like 1 and kappa-opioid receptors by nociceptin and dynorphin A. Mol Pharmacol (1999) 0.90
Lack of single-strand DNA-binding protein amplification under conditions of SOS induction in E. coli. Mol Gen Genet (1983) 0.90
Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4. Drug Metab Dispos (1998) 0.89
The biooxidation of cytotoxic ellipticine derivatives: a key to structure-activity relationship studies? Mol Pharmacol (1988) 0.88
Voltage-dependent introduction of a d[alpha]octothymidylate into electropermeabilized cells. Biochem Biophys Res Commun (1989) 0.88
Differential properties of the two Drosophila gamma-tubulin isotypes. Eur J Cell Biol (2001) 0.88
Circular oligomers in mitochondrial DNA of human and beef nonmalignant thyroid glands. Proc Natl Acad Sci U S A (1972) 0.88
[N-Methyl-9 hydroxy-ellipticine (NSC 264-137) in the treatment of malignant metastases. Preliminary results (author's transl)]. Nouv Presse Med (1981) 0.87
Synthesis, thermal stability and reactivity towards 9-aminoellipticine of double-stranded oligonucleotides containing a true abasic site. Nucleic Acids Res (1989) 0.87
Alpha-anomeric DNA: beta-RNA hybrids as new synthetic inhibitors of Escherichia coli RNase H, Drosophila embryo RNase H and M-MLV reverse transcriptase. Gene (1988) 0.87
[Kinetic study of the replicative forms of DNA in animal cells]. Biochim Biophys Acta (1967) 0.87
DNA bifunctional intercalators: antileukemic activity of new pyridocarbazole dimers. Biochem Pharmacol (1979) 0.86
A new DNA intercalating drug: Methoxy-9-ellipticine. FEBS Lett (1971) 0.86
Frameshift lesions induced by oxazolopyridocarbazoles are recognized by the mismatch repair system in Escherichia coli. Mutat Res (1988) 0.85
A yeast mitochondrial deoxyribonuclease stimulated by ethidium bromide. Biochem Biophys Res Commun (1972) 0.85
Rhazinilam mimics the cellular effects of taxol by different mechanisms of action. Cell Motil Cytoskeleton (1994) 0.85
[Isolation and fractionation of yeast deoxyribonucleic acid (DNA)]. C R Acad Sci Hebd Seances Acad Sci D (1966) 0.85
[Purification and properties of a snail (Helix pomatia L.) hepato-pancreas acid desoxyribonuclease]. C R Acad Sci Hebd Seances Acad Sci D (1966) 0.85
Cytostatic trans-platinum(II) complexes. J Med Chem (1989) 0.85
Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. J Med Chem (1981) 0.85
Syntheses and in vitro evaluation of water-soluble "cationic metalloporphyrin-ellipticine" molecules having a high affinity for DNA. J Med Chem (1991) 0.85
Magnetic force probe for nanoscale biomolecules. Phys Rev Lett (2005) 0.85
Cell cycle regulation of p34cdc2 kinase activity in Physarum polycephalum. J Cell Sci (1990) 0.85
Regulation of thymidine kinase synthesis during the cell cycle of Physarum polycephalum by the heat-sensitive system which triggers mitosis and S phase. Exp Cell Res (1979) 0.85
A randomised 2 x 2 factorial design to evaluate different smoking cessation methods. Rev Epidemiol Sante Publique (1992) 0.84
[Mitochondrial DNA of malignant cells]. Bull Cancer (1971) 0.84
Different levels of induction of RecA protein in E. coli (PQ 10) after treatment with two related carcinogens. Nucleic Acids Res (1983) 0.84
Efficient breakage of DNA apurinic sites by the indoleamine related 9-amino-ellipticine. Chem Biol Interact (1986) 0.84
Stimulation of topoisomerase II-mediated DNA cleavage by ellipticine derivatives: structure-activity relationship. Mol Pharmacol (1992) 0.84
Comparison of the structure-activity relationships of nociceptin and dynorphin A using chimeric peptides. FEBS Lett (1997) 0.84
Interactions between ellipticine and some derivatives and phospholipids in model membranes. FEBS Lett (1979) 0.84
Measurement of recA protein induction in Salmonella typhimurium: a possible biochemical test for the detection of DNA damaging agents. Biochimie (1983) 0.83
Quantification by fluorescence of apurinic sites in DNA. Biochem Biophys Res Commun (1987) 0.83
A molecular builder for carbohydrates: application to polysaccharides and complex carbohydrates. Biopolymers (1996) 0.83
Temperature modulation and quadrature detection for selective titration of two-state exchanging reactants. Anal Chem (2011) 0.83
alpha-DNA X: alpha and beta tetrathymidilates covalently linked to oxazolopyridocarbazolium (OPC): comparative stabilization of oligo beta-[dT]:oligo beta-[dA] and oligo alpha-[dT]:oligo beta-[dA] duplexes by the intercalating agent. Nucleic Acids Res (1989) 0.82
[A new antitumor compound: hydroxy-9 ellipticin. Effect on mouse L 1210 leukemia]. C R Acad Sci Hebd Seances Acad Sci D (1973) 0.82
The opiate receptor-binding interactions of opiate alkaloids and of an opioid peptide in rat brain membranes. Selection by manganese ions and by cholic acid (sodium salt) and minimalization of cross-reaction in vitro. Mol Pharmacol (1982) 0.82
Binding of Leu5-enkephalin and Met5-enkephalin to a particulate fraction from rat cerebrum. FEBS Lett (1977) 0.82
Inhibition of Moloney murine leukemia virus reverse transcriptase by alpha-anomeric oligonucleotides. Biochem Biophys Res Commun (1989) 0.82