Published in Proc Natl Acad Sci U S A on May 01, 1965
Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form. Proc Natl Acad Sci U S A (1969) 71.62
A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells. Proc Natl Acad Sci U S A (1967) 48.10
Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes. J Bacteriol (1974) 20.17
Physical and topological properties of circular DNA. J Gen Physiol (1966) 13.71
Molecular structure of bacterial plasmids. Bacteriol Rev (1972) 13.61
Evidence for circular DNA forms of a bacterial plasmid. Proc Natl Acad Sci U S A (1967) 10.45
Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae. Proc Natl Acad Sci U S A (1971) 10.06
Formation of covalent circles of lambda DNA by E. coli extracts. Proc Natl Acad Sci U S A (1967) 9.45
Cleavage of Simian virus 40 DNA at a unique site by a bacterial restriction enzyme. Proc Natl Acad Sci U S A (1972) 8.96
Properties of a R factor which originated in Pseudomonas aeruginosa 1822. J Bacteriol (1972) 8.56
Circular DNA forms of a bacterial sex factor. Proc Natl Acad Sci U S A (1967) 8.55
Mapping of closed circular DNAs by cleavage with restriction endonucleases and calibration by agarose gel electrophoresis. Proc Natl Acad Sci U S A (1977) 7.09
DNA of bacteriophage PM2: a closed circular double-stranded molecule. Proc Natl Acad Sci U S A (1969) 6.47
The writhing number of a space curve. Proc Natl Acad Sci U S A (1971) 5.35
Biology of bacterial deoxyribonucleic acid topoisomerases. Microbiol Rev (1984) 5.10
Self-transferable plasmids determining the hemolysin and bacteriocin of Streptococcus faecalis var. zymogenes. J Bacteriol (1975) 5.04
Behavior of supercoiled DNA. Biophys J (1998) 4.86
Modern analytical ultracentrifugation in protein science: a tutorial review. Protein Sci (2002) 4.86
Acquisition of sequences homologous to host deoxyribonucleic acid by closed circular simian virus 40 deoxyribonucleic acid. J Virol (1972) 4.81
The molecular basis of antibody formation: a paradox. Proc Natl Acad Sci U S A (1965) 4.68
Mitochondrial DNA from sheep heart. Proc Natl Acad Sci U S A (1966) 4.65
Cleavage of circular, superhelical simian virus 40 DNA to a linear duplex by S1 nuclease. J Virol (1973) 4.39
Extracellular nucleases of Pseudomonas BAL 31. I. Characterization of single strand-specific deoxyriboendonuclease and double-strand deoxyriboexonuclease activities. Nucleic Acids Res (1975) 4.16
The problems of eukaryotic and prokaryotic DNA packaging and in vivo conformation posed by superhelix density heterogeneity. Nucleic Acids Res (1977) 3.77
Evidence for semiconservative replication of circular polyoma DNA. Proc Natl Acad Sci U S A (1966) 3.71
Induction of cellular DNA synthesis by polyoma virus. Proc Natl Acad Sci U S A (1965) 3.63
Mutations in R factors of Escherichia coli causing an increased number of R-factor copies per chromosome. J Bacteriol (1972) 3.36
Extensive symmetrical transcription of Simian Virus 40 DNA in virus-yielding cells. Proc Natl Acad Sci U S A (1972) 2.68
Mouse cellular DNA enclosed in polyoma viral capsids (pseudovirions). Proc Natl Acad Sci U S A (1967) 2.64
Isolation of a polyoma-nucleoprotein complex from infected mouse-cell cultures. Proc Natl Acad Sci U S A (1971) 2.64
Hydroxyurea-induced accumulation of short fragments during polyoma DNA replication. I. Characterization of fragments. J Virol (1973) 2.57
Human papova (wart) virus. Bacteriol Rev (1967) 2.57
Plasmid in Bacillus pumilus and the enhanced sporulation of plasmid-negative variants. J Bacteriol (1973) 2.52
Inhibition in the joining of DNA intermediates to growing simian virus 40 chains. J Virol (1973) 2.44
Natural occurrence of cross-linked vaccinia virus deoxyribonucleic acid. J Virol (1970) 2.41
Regulation of bacterial DNA supercoiling: plasmid linking numbers vary with growth temperature. Proc Natl Acad Sci U S A (1984) 2.41
Induction of cellular deoxyribonuleic acid synthesis by simian virus 40. J Virol (1967) 2.39
Cytoplasmic DNA in the unfertilized sea urchin egg: physical properties of circular mitochondrial DNA and the occurrence of catenated forms. Proc Natl Acad Sci U S A (1968) 2.30
Replication of bacteriophage DNA, II. Structure of replicating DNA of phage lambda. Proc Natl Acad Sci U S A (1968) 2.29
Multiple-length rings in preparations of phi-X174 replicative form. Proc Natl Acad Sci U S A (1967) 2.19
Early events in the infection of permissive cells with simian virus 40: adsorption, penetration, and uncoating. J Virol (1970) 2.18
Circular DNA filaments from mouse mitochondria. Proc Natl Acad Sci U S A (1966) 2.16
Topological challenges to DNA replication: conformations at the fork. Proc Natl Acad Sci U S A (2001) 2.11
Replicating molecules of circular mitochondrial DNA. Proc Natl Acad Sci U S A (1968) 2.10
Polynucleotide ligase activity in cells infected with simian virus 40, polyoma virus, or vaccinia virus. J Virol (1969) 2.08
The amplification of ribosomal RNA genes involves a rolling circle intermediate. Proc Natl Acad Sci U S A (1973) 2.07
Physiochemical studies on interactions between DNA and RNA polymerase. Unwinding of the DNA helix by Escherichia coli RNA polymerase. Nucleic Acids Res (1977) 2.07
The replication of the ring-shaped DNA of polyoma virus. I. Identification of the replicative intermediate. Proc Natl Acad Sci U S A (1969) 2.06
The presence of ribonucleotides in mature closed-circular mitochondrial DNA. Proc Natl Acad Sci U S A (1973) 2.05
Nucleoprotein complexes in simian virus 40-infected cells. J Virol (1971) 2.03
Effect of supercoiling on the juxtaposition and relative orientation of DNA sites. Biophys J (1996) 1.97
DNA synthesized in the hepatitis B Dane particle DNA polymerase reaction. J Virol (1977) 1.92
Purification and partial characterization of the principal deoxyribonucleic acid polymerase from Mycoplasmatales. J Bacteriol (1977) 1.88
Properties of RP4, an R factor which originated in Pseudomonas aeruginosa S8. J Bacteriol (1972) 1.85
X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Res (1979) 1.76
A topological view of the replicon. EMBO Rep (2004) 1.76
Replication of the R factor Rts1 in Proteus mirabilis. J Bacteriol (1972) 1.70
Intracellular forms of adenovirus deoxyribonucleic acid. I. Evidence for a deoxyribonucleic acid-protein complex in baby hamster kidney cells infected with adenovirus type 12. J Virol (1972) 1.68
Structural roles of polyoma virus proteins. J Virol (1972) 1.67
Highly selective chemical modification of cruciform loops by diethyl pyrocarbonate. Nucleic Acids Res (1986) 1.61
In vitro reassembly of shell-like particles from disrupted polyoma virus. Proc Natl Acad Sci U S A (1971) 1.58
Genetic basis, epidemiology, and future significance of antibiotic resistance in Staphylococcus aureus: a review. J Clin Pathol (1973) 1.57
Isolation and characterization of the fertility factor P of Vibrio cholerae. J Bacteriol (1973) 1.56
Electron microscopy of the circular kinetoplastic DNA from Trypanosoma cruzi: occurrence of catenated forms. Proc Natl Acad Sci U S A (1969) 1.49
R factor deoxyribonucleic acid in chromosomeless progeny of Escherichia coli. J Bacteriol (1971) 1.46
Characterization of the Kilham rat virus. J Virol (1970) 1.44
Isolation and characterization of mitochondrial DNA from Drosophila melanogaster. J Cell Biol (1973) 1.43
Fragmentation of Bacillus bacteriophage phi105 DNA by complementary single-stranded DNA in the cohesive ends of the molecule. J Virol (1977) 1.42
Heart denaturation studies of rat liver mitrochondrial DNA. A denaturation map and changes in molecular configurations. J Cell Biol (1972) 1.40
Acquisition of sequences homologous to host DNA by closed circular simian virus 40 DNA. 3. Host sequences. J Virol (1973) 1.32
Underwound DNA under tension: structure, elasticity, and sequence-dependent behaviors. Phys Rev Lett (2011) 1.30
Endonucleolytic activity from Micrococcus luteus that acts on -ray-induced damage in plasmid DNA of Escherichia coli minicells. Proc Natl Acad Sci U S A (1972) 1.29
Transcription induces gyration of the DNA template in Escherichia coli. Proc Natl Acad Sci U S A (1988) 1.27
Granulosis virus deoxyribonucleic acid: a closed, double-stranded molecule. J Virol (1972) 1.25
SV40 DNA replication: from the A gene to a nanomachine. Virology (2008) 1.25
On the origin of tertiary turns in covalently closed double-stranded cyclic DNA. Proc Natl Acad Sci U S A (1967) 1.24
A topological approach to nucleosome structure and dynamics: the linking number paradox and other issues. Biophys J (1998) 1.24
Electrostatic-undulatory theory of plectonemically supercoiled DNA. Biophys J (1999) 1.24
Twisted circular DNA: sedimentation coefficients and the number of twists. Proc Natl Acad Sci U S A (1966) 1.23
Partial characterization of nucleoids and nucleoid-plasmid complexes from Salmonella typhimurium. J Bacteriol (1976) 1.23
Isolation of circular deoxyribonucleic acid from Salmonella typhosa hybrids obtained from matings with Escherichia coli Hfr donors. J Bacteriol (1971) 1.21
Biosynthetic properties of a polyoma nucleoprotein complex: evidence for replication sites. J Virol (1972) 1.21
The rolling circle for phi X DNA replication. 3. Synthesis of supercoiled duplex rings. Proc Natl Acad Sci U S A (1970) 1.17
Penicillin and tetracycline resistance plasmids in Staphylococcus epidermidis. Antimicrob Agents Chemother (1981) 1.16
Chemical studies on polyoma and Shope papilloma viruses. J Virol (1970) 1.12
Filamentous bacterial viruses. VI. Role of fd gene 2 in deoxyribonucleic acid replication. J Virol (1972) 1.11
Evidence for a composite state of an F'his, gnd element and a cryptic plasmid in a derivative of Salmonella typhimurium LT2. J Bacteriol (1974) 1.11
Replication of coliphage M-13. II. Intracellular deoxyribonucleic acid forms associated with M-13 infection of mitomycin C-treated cells. J Virol (1968) 1.09
Dynamics of cruciform extrusion in supercoiled DNA: use of a synthetic inverted repeat to study conformational populations. EMBO J (1983) 1.07
Extrachromosomal deoxyribonucleic acid in wild-type and photosynthetically incompetent strains of Rhodopseudomonas spheroides. J Bacteriol (1976) 1.05
The solution structure of a DNA hairpin containing a loop of three thymidines determined by nuclear magnetic resonance and molecular mechanics. Nucleic Acids Res (1991) 1.03
Light-scattering studies on supercoil unwinding. Biochem J (1973) 1.03
Studying genomic processes at the single-molecule level: introducing the tools and applications. Nat Rev Genet (2012) 1.02
Transformation and physical properties of R-factor RP4 transferred from Escherichia coli to Rhizobium trifolii. J Bacteriol (1973) 1.00
The importance of being supercoiled: how DNA mechanics regulate dynamic processes. Biochim Biophys Acta (2012) 1.00
Multiplication of polyoma virus in mouse-hamster somatic hybrids: a hybrid cell line which produces viral particles containing predominantly host deoxyribonucleic acid. J Virol (1971) 0.99
D-loop formation by Brh2 protein of Ustilago maydis. Proc Natl Acad Sci U S A (2008) 0.97
Topological relationship of prophage lambda to the bacterial chromosome in lysogenic cells. Proc Natl Acad Sci U S A (1970) 0.97
The mechanism of DNA strand breakage by vitamin C and superoxide and the protective roles of catalase and superoxide dismutase. Nucleic Acids Res (1976) 0.95
Stimulation of DNA-dependent RNA synthesis by a protein associated with ribosomes. Proc Natl Acad Sci U S A (1971) 0.94
SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA. J Mol Biol (1965) 36.76
THE NUCLEIC ACID OF SIMIAN VIRUS 40. Virology (1964) 12.56
Purification of polyoma virus. Virology (1963) 11.40
THE CYCLIC HELIX AND CYCLIC COIL FORMS OF POLYOMA VIRAL DNA. Proc Natl Acad Sci U S A (1963) 11.10
Band-centrifugation of macromolecules and viruses in self-generating density gradients. Proc Natl Acad Sci U S A (1963) 10.97
COHESION OF DNA MOLECULES ISOLATED FROM PHAGE LAMBDA. Proc Natl Acad Sci U S A (1963) 10.33
EVIDENCE FOR A RING STRUCTURE OF POLYOMA VIRUS DNA. Proc Natl Acad Sci U S A (1963) 8.94
The deoxyribonucleases of Escherichia coli. I. Purification and properties of a phosphodiesterase. J Biol Chem (1960) 8.66
The deoxyribonucleases of Escherichia coli. II. Purification and properties of a ribonucleic acid-inhibitable endonuclease. J Biol Chem (1962) 6.08
A STUDY OF SHOPE PAPILLOMA VIRUS DNA. J Mol Biol (1964) 4.70
The physical properties of the deoxyribonucleic acid from T7 bacteriophage. J Mol Biol (1962) 4.45
The denaturation and the renaturation of the DNA of polyoma virus. Proc Natl Acad Sci U S A (1963) 3.97
ELECTRON MICROSCOPY OF THE REPLICATIVE FORM OF THE DNA OF THE BACTERIOPHAGE PHI-X174. Science (1963) 3.66
The structure of the DNA of bacteriophage phi-X174. I. The action of exopolynucleotidases. J Mol Biol (1962) 3.18
STRUCTURE OF THE REPLICATIVE FORM OF BACTERIOPHAGE 0X174. Biochem Biophys Res Commun (1965) 2.90
PROCESS OF INFECTION WITH PHI-X174: EFFECT OF EXONUCLEASES ON THE REPLICATIVE FORM. Science (1963) 2.65
Ultracentrifuge studies with absorption optics. I. An automatic photoelectric scanning absorption system. Arch Biochem Biophys (1962) 2.50
CELL TRANSFORMATION BY DIFFERENT FORMS OF POLYOMA VIRUS DNA. Proc Natl Acad Sci U S A (1964) 2.39
A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells. Proc Natl Acad Sci U S A (1967) 48.10
EQUILIBRIUM SEDIMENTATION OF MACROMOLECULES IN DENSITY GRADIENTS. Proc Natl Acad Sci U S A (1957) 25.31
Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology (N Y) (1993) 22.41
Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase. Proc Natl Acad Sci U S A (1991) 16.94
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Action of nicking-closing enzyme on supercoiled and nonsupercoiled closed circular DNA: formation of a Boltzmann distribution of topological isomers. Proc Natl Acad Sci U S A (1975) 6.26
Characterization of a cis-Golgi matrix protein, GM130. J Cell Biol (1995) 6.22
Interaction of closed circular DNA with intercalative dyes. II. The free energy of superhelix formation in SV40 DNA. J Mol Biol (1970) 5.98
A buoyant method for the determination of the superhelix density of closed circular DNA. J Mol Biol (1971) 5.94
A novel closed-circular mitochondrial DNA with properties of a replicating intermediate. Proc Natl Acad Sci U S A (1971) 5.33
The use of an ethidium analogue in the dye-buoyant density procedure for the isolation of closed circular DNA: the variation of the superhelix density of mitochondrial DNA. Proc Natl Acad Sci U S A (1969) 5.21
Sequence heterogeneity in closed simian virus 40 deoxyribonucleic acid. J Virol (1972) 4.69
Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells. Proc Natl Acad Sci U S A (1972) 4.38
Early and late helix-coil transitions in closed circular DNA. The number of superhelical turns in polyoma DNA. J Mol Biol (1968) 4.04
The problems of eukaryotic and prokaryotic DNA packaging and in vivo conformation posed by superhelix density heterogeneity. Nucleic Acids Res (1977) 3.77
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