Published in Proc Natl Acad Sci U S A on April 01, 1969
A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res (1979) 214.95
Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J Bacteriol (1978) 75.38
Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA. Proc Natl Acad Sci U S A (1972) 57.06
Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. J Bacteriol (1972) 46.61
Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid. J Bacteriol (1976) 43.93
Plasmid ColEl as a molecular vehicle for cloning and amplification of DNA. Proc Natl Acad Sci U S A (1974) 32.46
General method for the isolation of plasmid deoxyribonucleic acid. J Bacteriol (1973) 31.68
Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid replication and catabolite repression of the plasmid deoxyribonucleic acid-protein relaxation complex. J Bacteriol (1973) 30.43
Isolation of large bacterial plasmids and characterization of the P2 incompatibility group plasmids pMG1 and pMG5. J Bacteriol (1978) 19.31
Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity. Proc Natl Acad Sci U S A (1977) 18.37
Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans. Infect Immun (1975) 14.65
Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis. J Bacteriol (1982) 14.27
Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA. Nucleic Acids Res (1982) 13.52
Characterization of Staphylococcus aureus plasmids introduced by transformation into Bacillus subtilis. J Bacteriol (1978) 10.31
Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1. Proc Natl Acad Sci U S A (1981) 10.04
Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli. J Bacteriol (1972) 9.50
Cloning, isolation, and characterization of replication regions of complex plasmid genomes. Proc Natl Acad Sci U S A (1975) 8.85
Origin of the TEM-beta-lactamase gene found on plasmids. J Bacteriol (1975) 8.70
Molecular nature of two nonconjugative plasmids carrying drug resistance genes. J Bacteriol (1974) 8.42
The gapped duplex DNA approach to oligonucleotide-directed mutation construction. Nucleic Acids Res (1984) 8.30
Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus. J Bacteriol (1988) 8.18
Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process. Mol Cell Biol (1984) 7.99
Plasmids, drug resistance, and gene transfer in the genus Streptococcus. Microbiol Rev (1981) 7.86
Interspecies homology of nitrogenase genes. Proc Natl Acad Sci U S A (1980) 7.47
Characterization of a mini-ColC1 plasmid. J Bacteriol (1976) 7.20
Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus. Proc Natl Acad Sci U S A (1982) 7.04
Detection of 5-methylcytosine in DNA sequences. Nucleic Acids Res (1978) 7.03
High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant. Antimicrob Agents Chemother (1986) 6.34
Directed mutagenesis of DNA cloned in filamentous phage: influence of hemimethylated GATC sites on marker recovery from restriction fragments. Nucleic Acids Res (1982) 5.72
Nature of R-factor replication in the presence of chloramphenicol. Proc Natl Acad Sci U S A (1975) 5.64
Replication and expression of plasmids from Staphylococcus aureus in Bacillus subtilis. Proc Natl Acad Sci U S A (1977) 5.55
Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase. Proc Natl Acad Sci U S A (1983) 5.50
Regions of broad-host-range plasmid RK2 which are essential for replication and maintenance. J Bacteriol (1980) 5.45
ATP-dependent renaturation of DNA catalyzed by the recA protein of Escherichia coli. Proc Natl Acad Sci U S A (1979) 5.39
In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites. Proc Natl Acad Sci U S A (1978) 5.32
Temperature-sensitive mutants for the replication of plasmids in Escherichia coli: requirement for deoxyribonucleic acid polymerase I in the replication of the plasmid ColE 1 . J Bacteriol (1973) 5.24
Use of a single-strand specific nuclease for analysis of bacterial and plasmid deoxyribonucleic acid homo- and heteroduplexes. J Bacteriol (1973) 5.23
Maize chloroplast DNA fragment encoding the large subunit of ribulosebisphosphate carboxylase. Proc Natl Acad Sci U S A (1977) 5.20
ColV plasmid-mediated, colicin V-independent iron uptake system of invasive strains of Escherichia coli. Infect Immun (1980) 5.18
Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells. Proc Natl Acad Sci U S A (1986) 5.00
A short primer for sequencing DNA cloned in the single-stranded phage vector M13mp2. Nucleic Acids Res (1980) 4.98
Processing of plasmid DNA during bacterial conjugation. Microbiol Rev (1984) 4.83
Molecular and genetic studies of an R factor system consisting of independent transfer and drug resistance plasmids. J Bacteriol (1973) 4.81
Yeast genes fused to beta-galactosidase in Escherichia coli can be expressed normally in yeast. Proc Natl Acad Sci U S A (1981) 4.79
Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2. Proc Natl Acad Sci U S A (1971) 4.76
Cloning of influenza cDNA ino M13: the sequence of the RNA segment encoding the A/PR/8/34 matrix protein. Nucleic Acids Res (1980) 4.75
A novel in vitro transcription-translation system: accurate and efficient synthesis of single proteins from cloned DNA sequences. EMBO J (1984) 4.50
Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali. Proc Natl Acad Sci U S A (1972) 4.46
Biochemical construction and selection of hybrid plasmids containing specific segments of the Escherichia coli genome. Proc Natl Acad Sci U S A (1975) 4.33
Role of bacterial cellulose fibrils in Agrobacterium tumefaciens infection. J Bacteriol (1983) 4.30
Electrophoretic transfer of DNA, RNA and protein onto diazobenzyloxymethyl (DBM) - paper. Nucleic Acids Res (1980) 4.30
Cloning of the symbiotic region of Rhizobium leguminosarum: the nodulation genes are between the nitrogenase genes and a nifA-like gene. EMBO J (1983) 4.28
Utilization of two distinct modes of replication by a hybrid plasmid constructed in vitro from separate replicons. Proc Natl Acad Sci U S A (1974) 4.27
DNA cloning in Bacillus subtilis. Proc Natl Acad Sci U S A (1978) 4.26
Analysis of the constancy of DNA sequences during development and evolution of the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1979) 4.26
Efficient expression of Escherichia coli galactokinase gene in mammalian cells. Proc Natl Acad Sci U S A (1982) 4.25
Introduction of transposon Tn5 into Myxococcus for analysis of developmental and other nonselectable mutants. Proc Natl Acad Sci U S A (1981) 4.19
Nucleotide sequence of the enterotoxin B gene from Staphylococcus aureus. J Bacteriol (1986) 4.13
Molecular studies of R factor compatibility groups. J Bacteriol (1973) 4.12
A new method for the purification and identification of covalently closed circular DNA molcules. Nucleic Acids Res (1978) 4.09
Mini-F plasmid genes that couple host cell division to plasmid proliferation. Proc Natl Acad Sci U S A (1983) 4.07
Genetic recombination and complementation between bacteriophage T7 and cloned fragments of T7 DNA. Proc Natl Acad Sci U S A (1978) 4.01
Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein. J Virol (1983) 3.98
tRNA genes are found between 16S and 23S rRNA genes in Bacillus subtilis. Nucleic Acids Res (1982) 3.93
Isolation of cDNA clones for the human complement protein factor B, a class III major histocompatibility complex gene product. Proc Natl Acad Sci U S A (1982) 3.89
Polynucleotide sequence relationships among Ent plasmids and the relationship between Ent and other plasmids. J Bacteriol (1975) 3.88
Oligonucleotide directed mutagenesis of the human beta-globin gene: a general method for producing specific point mutations in cloned DNA. Nucleic Acids Res (1981) 3.87
UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA. Proc Natl Acad Sci U S A (1988) 3.85
Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta. Proc Natl Acad Sci U S A (1983) 3.79
RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes. Proc Natl Acad Sci U S A (1979) 3.78
Cloning and analysis of strong promoters is made possible by the downstream placement of a RNA termination signal. Proc Natl Acad Sci U S A (1981) 3.77
Mechanism of integrating foreign DNA during transformation of Bacillus subtilis. Proc Natl Acad Sci U S A (1978) 3.74
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch. Proc Natl Acad Sci U S A (1980) 3.70
Transcriptional and post-transcriptional regulation of ribulose 1,5-bisphosphate carboxylase gene expression in light- and dark-grown amaranth cotyledons. Mol Cell Biol (1985) 3.69
Replication of colicin E1 plasmid DNA added to cell extracts. Proc Natl Acad Sci U S A (1975) 3.66
Identification and radiochemical purification of the recA protein of Escherichia coli K-12. Proc Natl Acad Sci U S A (1976) 3.64
The maize chloroplast genes for the beta and epsilon subunits of the photosynthetic coupling factor CF1 are fused. Nucleic Acids Res (1982) 3.63
Structure of the sucrose synthase gene on chromosome 9 of Zea mays L. EMBO J (1985) 3.62
Location and nucleotide sequence of the transfer origin of the broad host range plasmid RK2. Proc Natl Acad Sci U S A (1983) 3.61
Isolation and characterization of the protein coded by gene A of bacteriophage phiX174 DNA. Proc Natl Acad Sci U S A (1976) 3.56
Colicinogeny and related phenomena. Bacteriol Rev (1975) 3.51
Nucleotide sequence of the envelope gene of Friend murine leukemia virus. J Virol (1983) 3.41
Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector. Proc Natl Acad Sci U S A (1981) 3.38
Five novel plasmid-determined beta-lactamases. Antimicrob Agents Chemother (1985) 3.34
Molecular cloning of DNA fragments produced by restriction endonucleases Sa1I and BamI. Proc Natl Acad Sci U S A (1976) 3.32
Characterization of an Escherichia coli plasmid encoding for synthesis of heat-labile toxin: molecular cloning of the toxin determinant. Infect Immun (1978) 3.28
Role of primary structure and disulfide bond formation in beta-lactamase secretion. J Bacteriol (1983) 3.26
Synthesis of hepatitis B surface antigen in mammalian cells: expression of the entire gene and the coding region. J Virol (1983) 3.24
Primary sequence of the 5' flanking regions of the Drosophila heat shock genes in chromosome subdivision 67B. Nucleic Acids Res (1981) 3.21
Digestion of highly modified bacteriophage DNA by restriction endonucleases. Nucleic Acids Res (1982) 3.20
Deletion of the nontransforming Epstein-Barr virus strain P3HR-1 causes fusion of the large internal repeat to the DSL region. J Virol (1982) 3.16
Detailed characterization of the mRNA mapping in the HindIII fragment K region of the herpes simplex virus type 1 genome. J Virol (1981) 3.10
Identification and characterization of recombinant plasmids carrying the complete qa gene cluster from Neurospora crassa including the qa-1+ regulatory gene. Proc Natl Acad Sci U S A (1981) 3.07
Mitomycin C-induced expression of trpA of Salmonella typhimurium inserted into the plasmid ColE1. J Bacteriol (1977) 3.06
A cosmid for selecting genes by complementation in Aspergillus nidulans: Selection of the developmentally regulated yA locus. Proc Natl Acad Sci U S A (1985) 3.04
DNA sequence and transcriptional organization of essential cell division genes ftsQ and ftsA of Escherichia coli: evidence for overlapping transcriptional units. J Bacteriol (1984) 3.04
Molecular nature of two beta-lactamase-specifying plasmids isolated from Haemophilus influenzae type b. J Bacteriol (1976) 3.03
Herpes simplex virus type 1 HindIII fragment L encodes spliced and complementary mRNA species. J Virol (1981) 2.97
Nonenteric toxins of Staphylococcus aureus. Microbiol Rev (1979) 2.95
Supercoiling energy and nucleosome formation: the role of the arginine-rich histone kernel. Nucleic Acids Res (1977) 2.94
Circular DNA forms of colicinogenic factors E1, E2 and E3 from Escherichia coli. J Mol Biol (1968) 23.73
The twisted circular form of polyoma viral DNA. Proc Natl Acad Sci U S A (1965) 20.04
The interaction of closed circular DNA with intercalative dyes. I. The superhelix density of SV40 DNA in the presence and absence of dye. J Mol Biol (1968) 16.72
Characterization of multiple circular DNA forms of colicinogenic factor E-1 from Proteus mirabilis. Biochemistry (1968) 14.82
Physical and topological properties of circular DNA. J Gen Physiol (1966) 13.71
Evidence for circular DNA forms of a bacterial plasmid. Proc Natl Acad Sci U S A (1967) 10.45
Circular DNA forms of a bacterial sex factor. Proc Natl Acad Sci U S A (1967) 8.55
Lysis of Escherichia coli with a neutral detergent. Biochim Biophys Acta (1967) 8.51
ALLOSTERIC INHIBITION OF RAT LIVER FRUCTOSE 1,6-DIPHOSPHATASE BY ADENOSINE 5'-MONOPHOSPHATE. J Biol Chem (1965) 7.97
Effect of Rec mutations on the activity of colicinogenic factors. J Bacteriol (1967) 7.19
Preparation and purification of phi X-RF component I. Biochim Biophys Acta (1968) 7.06
Process of infection with bacteriophage phiX174. XX. Attachment of the parental DNA of bacteriophage phiX174 to a fast-sedimenting cell component. J Mol Biol (1968) 6.63
Conformational changes in aspartate transcarbamylase. I. Proteolysis of the intact enzyme. J Biol Chem (1968) 5.34
Studies of the nature of the inhibitory action of inorganic phosphate, fluoride, and detergents on 5'-adenylic acid deaminase activity and on the activation by adenosine triphosphate. J Biol Chem (1968) 5.20
Nature of Col E 1 plasmid replication in Escherichia coli in the presence of the chloramphenicol. J Bacteriol (1972) 46.61
Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Proc Natl Acad Sci U S A (1980) 45.02
Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. Proc Natl Acad Sci U S A (1979) 44.75
Plasmid ColEl as a molecular vehicle for cloning and amplification of DNA. Proc Natl Acad Sci U S A (1974) 32.46
Stimulation by cyclic adenosine monophosphate of plasmid deoxyribonucleic acid replication and catabolite repression of the plasmid deoxyribonucleic acid-protein relaxation complex. J Bacteriol (1973) 30.43
Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol (1987) 26.70
Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event. Biochemistry (1970) 26.22
Circular DNA forms of colicinogenic factors E1, E2 and E3 from Escherichia coli. J Mol Biol (1968) 23.73
Characterization of multiple circular DNA forms of colicinogenic factor E-1 from Proteus mirabilis. Biochemistry (1968) 14.82
Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2. Methods Enzymol (1979) 13.61
Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance. J Bacteriol (1974) 12.44
Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring gene expression. Plasmid (1985) 11.74
Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J Bacteriol (1981) 11.15
Evidence for circular DNA forms of a bacterial plasmid. Proc Natl Acad Sci U S A (1967) 10.45
Circular DNA. Annu Rev Biochem (1971) 9.75
Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone. Proc Natl Acad Sci U S A (1978) 9.67
Effect of growth conditions on the formation of the relaxation complex of supercoiled ColE1 deoxyribonucleic acid and protein in Escherichia coli. J Bacteriol (1972) 9.50
DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1. Biochem Biophys Res Commun (1970) 8.73
Transmissible toxin (hemolysin) plasmid in Streptococcus faecalis and its mobilization of a noninfectious drug resistance plasmid. J Bacteriol (1975) 8.65
Circular DNA forms of a bacterial sex factor. Proc Natl Acad Sci U S A (1967) 8.55
Trans-complementation-dependent replication of a low molecular weight origin fragment from plasmid R6K. Cell (1978) 8.28
Plasmids, drug resistance, and gene transfer in the genus Streptococcus. Microbiol Rev (1981) 7.86
Plasmid transfer in Streptococcus faecalis: production of multiple sex pheromones by recipients. Plasmid (1979) 7.20
Characterization of a mini-ColC1 plasmid. J Bacteriol (1976) 7.20
Effect of Rec mutations on the activity of colicinogenic factors. J Bacteriol (1967) 7.19
Replication of a bacterial plasmid and an episome in Escherichia coli. Biochemistry (1970) 7.19
Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917. J Bacteriol (1982) 7.03
Complete nucleotide sequence of macrolide-lincosamide-streptogramin B-resistance transposon Tn917 in Streptococcus faecalis. J Bacteriol (1985) 7.00
Regeneration of insertionally inactivated streptococcal DNA fragments after excision of transposon Tn916 in Escherichia coli: strategy for targeting and cloning of genes from gram-positive bacteria. J Bacteriol (1984) 6.82
Unidirectional replication of the P-group plasmid RK2. Biochim Biophys Acta (1977) 6.17
Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis. J Bacteriol (1980) 6.06
Transient and stable expression of the firefly luciferase gene in plant cells and transgenic plants. Science (1986) 5.97
Heme biosynthesis in Rhizobium. Identification of a cloned gene coding for delta-aminolevulinic acid synthetase from Rhizobium meliloti. J Biol Chem (1982) 5.80
Method for the isolation of the replication region of a bacterial replicon: construction of a mini-F'kn plasmid. J Bacteriol (1976) 5.75
Purification and characterization of colicin E2 and colicin E3. J Biol Chem (1967) 5.74
A transposon in Streptococcus faecalis with fertility properties. Nature (1982) 5.65
A catenated DNA molecule as an intermediate in the replication of the resistance transfer factor R6K in Escherichia coli. Biochem Biophys Res Commun (1973) 5.47
Regions of broad-host-range plasmid RK2 which are essential for replication and maintenance. J Bacteriol (1980) 5.45
Highly efficient protoplast transformation system for Streptococcus faecalis and a new Escherichia coli-S. faecalis shuttle vector. J Bacteriol (1986) 5.35
Novel shuttle plasmid vehicles for Escherichia-Streptococcus transgeneric cloning. Gene (1983) 5.30
Plasmid-related transmissibility and multiple drug resistance in Streptococcus faecalis subsp. zymogenes strain DS16. Antimicrob Agents Chemother (1979) 5.28
Modification of Streptococcus faecalis sex pheromones after acquisition of plasmid DNA. Proc Natl Acad Sci U S A (1983) 5.27
Temperature-sensitive mutants for the replication of plasmids in Escherichia coli: requirement for deoxyribonucleic acid polymerase I in the replication of the plasmid ColE 1 . J Bacteriol (1973) 5.24
Gene cloning and containment properties of plasmid Col E1 and its derivatives. Science (1977) 5.21
Comparative study of the events associated with colicin induction. J Bacteriol (1967) 5.14
A cloning vector able to replicate in Escherichia coli and Streptococcus sanguis. Gene (1982) 5.13
Conjugative transposons and the dissemination of antibiotic resistance in streptococci. Annu Rev Microbiol (1986) 5.08
Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2. Proc Natl Acad Sci U S A (1971) 4.76
Suppression of Co1E1 replication properties by the Inc P-1 plasmid RK2 in hybrid plasmids constructed in vitro. J Mol Biol (1979) 4.69
Recombination-deficient mutant of Streptococcus faecalis. J Bacteriol (1980) 4.60
Isolation and characterization of plasmid deoxyribonucleic acid from Streptococcus mutans. J Bacteriol (1973) 4.59
The DNA-protein relaxation complex of the plasmid RK2: location of the site-specific nick in the region of the proposed origin of transfer. Mol Gen Genet (1979) 4.48
Characterization of a plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain Streptococcus pyogenes. Antimicrob Agents Chemother (1974) 4.47
Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali. Proc Natl Acad Sci U S A (1972) 4.46
A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti. Nature (1991) 4.45
Generation in vitro of deletions in the broad host range plasmid RK2 using phage Mu insertions and a restriction endonuclease. Gene (1976) 4.35
Physical and genetic studies with restriction endonucleases on the broad host-range plasmid RK2. Mol Gen Genet (1977) 4.28
Purification and characterization of colicin E1. J Biol Chem (1971) 4.27
Unidirectional replication of plasmid ColE1 DNA. Nature (1974) 4.27
Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis. J Mol Biol (1994) 4.23
Plasmid-determined tetracycline resistance in Streptococcus faecalis: evidence for gene amplification during growth in presence of tetracycline. Proc Natl Acad Sci U S A (1975) 4.21
Generation of higher multiple circular DNA forms in bacteria. Proc Natl Acad Sci U S A (1968) 3.98
Regions of broad-host-range plasmid RK2 involved in replication and stable maintenance in nine species of gram-negative bacteria. J Bacteriol (1985) 3.93
Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918). J Bacteriol (1985) 3.84
Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice. Infect Immun (1984) 3.83
Plasmid content of Streptococcus faecalis strain 39-5 and identification of a pheromone (cPD1)-induced surface antigen. J Gen Microbiol (1983) 3.80
Genetic analysis of the pAD1 pheromone response in Streptococcus faecalis, using transposon Tn917 as an insertional mutagen. J Bacteriol (1984) 3.69
Rhizobium meliloti genes required for nodule development are related to chromosomal virulence genes in Agrobacterium tumefaciens. Proc Natl Acad Sci U S A (1986) 3.38
Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc Natl Acad Sci U S A (1985) 3.35
Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis. Antimicrob Agents Chemother (1993) 3.35
Structural relationships among Rhizobium meliloti symbiotic promoters. Cell (1983) 3.23
Genetic organization of the bacterial conjugative transposon Tn916. J Bacteriol (1988) 3.18
Direct inhibition of Col E 1 plasmid DNA replication in Escherichia coli by rifampicin. Nat New Biol (1972) 3.05
Nucleotide sequence of the 18-kb conjugative transposon Tn916 from Enterococcus faecalis. Plasmid (1994) 3.01
Construction of plasmid cloning vehicles that promote gene expression from the bacteriophage lambda pL promoter. Gene (1979) 3.00
Molecular vehicle properties of the broad host range plasmid RK2. Science (1975) 2.97
Plasmid-determined resistance to erythromycin: comparison of strains of streptococcus faecalis and streptococcus pyogenes with regard to plasmid hmology and resistance inducibility. Antimicrob Agents Chemother (1975) 2.91
Isolation and characterization of the recA gene of Rhizobium meliloti. J Bacteriol (1983) 2.89
Transfer functions of the Streptococcus faecalis plasmid pAD1: organization of plasmid DNA encoding response to sex pheromone. J Bacteriol (1987) 2.87
Conjugative transfer of R-plasmids from Streptococcus faecalis to Staphylococcus aureus. Antimicrob Agents Chemother (1982) 2.85
Strand and site specificity of the relaxation event for the relaxation complex of the antibiotic resistance plasmid R6K. Biochemistry (1974) 2.81
Evidence for conjugal transfer of a Streptococcus faecalis transposon (Tn916) from a chromosomal site in the absence of plasmid DNA. Cold Spring Harb Symp Quant Biol (1981) 2.80
Plasmid-determined tetracycline resistance in Streptococcus faecalis: tandemly repeated resistance determinants in amplified forms of pAMalpha1 DNA. J Mol Biol (1976) 2.79
Use of the lambda phage promoter PL to promote gene expression in hybrid plasmid cloning vehicles. Methods Enzymol (1979) 2.74
Clustering of nitrogen fixation (nif) genes in Rhizobium meliloti. J Bacteriol (1982) 2.66
A transposon (Tn917) in Streptococcus faecalis that exhibits enhanced transposition during induction of drug resistance. Cold Spring Harb Symp Quant Biol (1979) 2.64
F 1 sex factor of Escherichia coli. Size and purification in the form of a strand-specific relaxation complex of supercoiled deoxyribonucleic acid and protein. Biochemistry (1971) 2.63
Simple and reliable multiplex PCR assay for surveillance isolates of vancomycin-resistant enterococci. J Clin Microbiol (2000) 2.62
The FixL protein of Rhizobium meliloti can be separated into a heme-binding oxygen-sensing domain and a functional C-terminal kinase domain. Proc Natl Acad Sci U S A (1992) 2.51
The ndvA gene product of Rhizobium meliloti is required for beta-(1----2)glucan production and has homology to the ATP-binding export protein HlyB. J Bacteriol (1988) 2.45
High incidence of hemolysin production by Enterococcus (Streptococcus) faecalis strains associated with human parenteral infections. J Clin Microbiol (1987) 2.42
A conjugative transposon (Tn919) in Streptococcus sanguis. Infect Immun (1985) 2.41
Nucleotide sequence of the gelatinase gene (gelE) from Enterococcus faecalis subsp. liquefaciens. Infect Immun (1991) 2.41
Plasmid determined resistance to antibiotics: molecular properties of R factors. Annu Rev Microbiol (1973) 2.39
Nucleotide sequence of the region of the origin of replication of the broad host range plasmid RK2. Mol Gen Genet (1981) 2.38