Published in Endocrinology on December 01, 1968
Effect of synthetic ovine corticotropin-releasing factor. Dose response of plasma adrenocorticotropin and cortisol. J Clin Invest (1983) 1.14
Vasopressin stimulation of adrenocorticotropin hormone (ACTH) in humans. In vivo bioassay of corticotropin-releasing factor (CRF) which provides evidence for CRF mediation of the diurnal rhythm of ACTH. J Clin Invest (1988) 0.82
Hypophysiotropic and neuromodulatory regulation of adrenocorticotropin in the human fetal pituitary gland. J Clin Invest (1986) 0.81
High molecular weight peptide with corticotropin-releasing factor activity from porcine hypothalami. Proc Natl Acad Sci U S A (1981) 0.80
Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science (1981) 9.64
Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science (1973) 7.47
Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse. J Comp Neurol (2000) 4.17
The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J Comp Neurol (1992) 3.53
Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor. Science (1987) 3.45
Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron (1998) 3.08
Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients. Science (1984) 2.83
Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A. Mol Cell Biol (1993) 2.79
beta-Endorphin and adrenocorticotropin are selected concomitantly by the pituitary gland. Science (1977) 2.68
Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour. Nature (1982) 2.44
Draft guidance for industry extended-release solid oral dosage forms. Development, evaluation and application of in vitro-in vivo correlations. Adv Exp Med Biol (1997) 2.35
Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature (1986) 2.29
Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell (1990) 2.22
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature (2000) 2.17
Distribution of corticotropin-releasing factor receptor mRNA expression in the rat brain and pituitary. Proc Natl Acad Sci U S A (1994) 2.14
Culture of enzymatically dispersed pituitary cells: functional validation of a method. Endocrinology (1972) 2.09
Rapid regression of uterine leiomyomas in response to daily administration of gonadotropin-releasing hormone antagonist. Fertil Steril (1993) 2.09
Appetite-suppressing effects of urocortin, a CRF-related neuropeptide. Science (1996) 1.91
Synthetic competitive antagonists of corticotropin-releasing factor: effect on ACTH secretion in the rat. Science (1984) 1.87
Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart. Proc Natl Acad Sci U S A (1995) 1.86
Chemical and biological characterization of corticotropin releasing factor. Recent Prog Horm Res (1983) 1.86
Corticotropin releasing factor produces behavioural activation in rats. Nature (1982) 1.82
Suppression of pancreatic endocrine tumour secretion by long-acting somatostatin analogue. Lancet (1979) 1.81
Primary structure of corticotropin-releasing factor from ovine hypothalamus. Proc Natl Acad Sci U S A (1981) 1.78
Corticotropin releasing factor decreases postburst hyperpolarizations and excites hippocampal neurons. Science (1983) 1.77
Somatostatin. Recent Prog Horm Res (1975) 1.67
Preliminary observations on the effect of synthetic thyrotropin releasing factor on plasma thyrotropin levels in man. J Clin Endocrinol Metab (1970) 1.67
Regulatory peptides of the hypothalamus. Annu Rev Physiol (1977) 1.64
Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin. Nature (1983) 1.64
Differential regulation of corticotropin-releasing factor mRNA in rat brain regions by glucocorticoids and stress. J Neurosci (1991) 1.62
Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor. J Clin Invest (1982) 1.60
Corticotropin-releasing factor: actions on the sympathetic nervous system and metabolism. Endocrinology (1982) 1.58
Characterization of rat hypothalamic corticotropin-releasing factor. Proc Natl Acad Sci U S A (1983) 1.58
"Medical oophorectomy" using a long-acting GNRH agonist--a possible new approach to the treatment of endometriosis. J Clin Endocrinol Metab (1982) 1.57
Urocortin-1 and -2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits. Mol Psychiatry (2009) 1.57
Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty. Life Sci (1982) 1.57
Reversible inhibition of testicular steroidogenesis and spermatogenesis by a potent gonadotropin-releasing hormone agonist in normal men: an approach toward the development of a male contraceptive. N Engl J Med (1981) 1.57
Primary structure of the ovine hypothalamic luteinizing hormone-releasing factor (LRF) (LH-hypothalamus-LRF-gas chromatography-mass spectrometry-decapeptide-Edman degradation). Proc Natl Acad Sci U S A (1972) 1.57
Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells. Endocrinology (1990) 1.56
Corticotropin releasing factor produces increases in brain excitability and convulsive seizures in rats. Brain Res (1983) 1.55
Assay of corticotropin releasing factor. Methods Enzymol (1983) 1.53
Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists. J Med Chem (2002) 1.53
The functional neuroanatomy of corticotropin-releasing factor. Ciba Found Symp (1993) 1.52
Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene. J Biol Chem (1995) 1.49
Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins. Proc Natl Acad Sci U S A (1996) 1.46
Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like" effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats. Psychopharmacology (Berl) (1999) 1.46
Effect of ethanol on the hypothalamic-pituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF). J Pharmacol Exp Ther (1984) 1.46
Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor. Proc Natl Acad Sci U S A (1995) 1.45
The effect of somatostatin analogs on secretion of growth, pancreatic, and gastrointestinal hormones in man. J Clin Endocrinol Metab (1981) 1.42
CRF2 receptor activation prevents colorectal distension induced visceral pain and spinal ERK1/2 phosphorylation in rats. Gut (2005) 1.41
Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions. Proc Natl Acad Sci U S A (1988) 1.40
Correction of hyperglycemia in diabetic mice transplanted with reversibly immortalized pancreatic beta cells controlled by the tet-on regulatory system. Cell Transplant (2001) 1.39
Insulin-dependent diabetes mellitus induced by subdiabetogenic doses of streptozotocin: obligatory role of cell-mediated autoimmune processes. Proc Natl Acad Sci U S A (1980) 1.39
Detection and purification of inhibin using antisera generated against synthetic peptide fragments. Methods Enzymol (1989) 1.38
Effects of somatostatin on the secretion of thyrotropin and prolactin. Endocrinology (1974) 1.38
Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo. Endocrinology (1983) 1.38
Characterization of ovine hypothalamic hypophysiotropic TSH-releasing factor. Nature (1970) 1.36
Ontogeny of the stress response in the rat: role of the pituitary and the hypothalamus. Endocrinology (1986) 1.36
Isolation and sequence analysis of a somatostatin-like polypeptide from ovine hypothalamus. Biochemistry (1981) 1.35
Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction. N Engl J Med (1984) 1.35
Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice. Endocrinology (1992) 1.34
Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase. Proc Natl Acad Sci U S A (1997) 1.34
Isolation and characterization of somatostatin from pigeon pancreas. Proc Natl Acad Sci U S A (1979) 1.34
Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor. Endocrinology (1985) 1.32
In vivo corticotropin-releasing factor-induced secretion of adrenocorticotropin, beta-endorphin, and corticosterone. Endocrinology (1982) 1.32
The rat melanin-concentrating hormone messenger ribonucleic acid encodes multiple putative neuropeptides coexpressed in the dorsolateral hypothalamus. Endocrinology (1989) 1.28
Presence of calcium ions as a requisite for the in vitro stimulation of TSH-release by hypothalamic TRF. Experientia (1967) 1.27
Transcriptional regulation of growth hormone gene expression by growth hormone-releasing factor. Nature (1983) 1.27
Purification, amino acid composition and N-terminus of the hypothalamic luteinizing hormone releasing factor (LRF) of ovine origin. Biochem Biophys Res Commun (1971) 1.27
Corticotropin releasing factor (CRF): immunoreactive neurones and fibers in rat hypothalamus. Regul Pept (1982) 1.27
Purification and partial characterization of inhibin from porcine follicular fluid. Biochem Biophys Res Commun (1985) 1.27
Characterization of a teleost gonadotropin-releasing hormone. Proc Natl Acad Sci U S A (1983) 1.26
Involvement of adenosine 3',5'-monophosphate in release of ACTH. Am J Physiol (1969) 1.26
D-Trp8-somatostatin: an analog of somatostatin more potent than the native molecule. Biochem Biophys Res Commun (1975) 1.24
Characterization of rat hypothalamic growth hormone-releasing factor. Nature (1983) 1.24
The role of calmodulin in the regulation of protein phosphorylation and insulin release in hamster insulinoma cells. J Biol Chem (1980) 1.24
Biologic and immunologic activities and applications of somatostatin analogs. Metabolism (1978) 1.23
Human pancreatic growth-hormone-releasing factor selectively stimulates growth-hormone secretion in man. Lancet (1983) 1.23
Release of immunoreactive somatostatin from the pancreas in response to glucose, amino acids, pancreozymin-cholecystokinin, and tolbutamide. J Clin Invest (1977) 1.22
Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. Am J Physiol (1986) 1.22
Inhibition of growth hormone release in humans by somatostatin. J Clin Endocrinol Metab (1973) 1.22
Calcium-dependent release of somatostatin and neurotensin from rat brain in vitro. Nature (1978) 1.21
Expression-cloning and sequence of a cDNA encoding human growth hormone-releasing factor. Nature (1983) 1.20
Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells. Mol Cell Biol (1990) 1.20
Influence of corticotropin-releasing factor on reproductive functions in the rat. Endocrinology (1984) 1.20
Evidence for an autocrine role of activin B within rat anterior pituitary cultures. Endocrinology (1991) 1.19
Glucose induces insulin gene transcription in a murine pancreatic beta-cell line. J Biol Chem (1991) 1.19
Corticotropin-releasing factor (CRF): central effects on mean arterial pressure and heart rate in rats. Endocrinology (1982) 1.19
A conservative approach to the management of uterine leiomyoma: pituitary desensitization by a luteinizing hormone-releasing hormone analogue. Am J Obstet Gynecol (1983) 1.19
Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. Proc Natl Acad Sci U S A (1982) 1.18
Ca2+-dependent protein phosphorylation and insulin release in intact hamster insulinoma cells. Inhibition by trifluoperazine. J Biol Chem (1980) 1.17
Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion. Proc Natl Acad Sci U S A (1994) 1.17
Therapeutic use of pituitary desensitization with a long-acting lhrh agonist: a potential new treatment for idiopathic precocious puberty. J Clin Endocrinol Metab (1981) 1.17
ACTH antibodies in patients receiving depot porcine ACTH to hasten recovery from pituitary-adrenal suppression. J Clin Invest (1967) 1.16
Bombesin:potent effects on thermoregulation in the rat. Science (1977) 1.16
Inhibin A-subunit cDNAs from porcine ovary and human placenta. Proc Natl Acad Sci U S A (1986) 1.16
In the mouse, the activation of the hypothalamic-pituitary-adrenal axis by a lipopolysaccharide (endotoxin) is mediated through interleukin-1. Endocrinology (1989) 1.16
Diminished responsiveness of the hypothalamic-pituitary-adrenal axis of the rat during exposure to prolonged stress: a pituitary-mediated mechanism. Endocrinology (1987) 1.15
Studies of ACTH antibodies and their reactions with inactive analogues of ACTH. Endocrinology (1966) 1.15