Published in J Biol Chem on April 10, 1971
Enzymatic activities associated with a purified simian virus 40 T antigen-related protein. Proc Natl Acad Sci U S A (1979) 3.82
Analytical study of microsomes and isolated subcellular membranes from rat liver. I. Biochemical methods. J Cell Biol (1974) 3.69
Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1981) 3.07
Protein kinase and phosphoproteins of vesicular stomatitis virus. J Virol (1974) 2.11
Thrombin-induced protein phosphorylation in human platelets. J Clin Invest (1975) 1.76
Activation of protein kinase by physiological concentrations of cyclic AMP. Proc Natl Acad Sci U S A (1974) 1.75
Purification and characterization of the catalytic subunit of adenosine 3':5'-cyclic monophosphate-dependent protein kinase from bovine liver. Biochem J (1976) 1.57
Studies on the phosphorylation of the inhibitory subunit of troponin during modification of contraction in perfused rat heart. Biochem J (1976) 1.55
Purification and properties of myosin light-chain kinase from fast skeletal muscle. Biochem J (1977) 1.52
Interaction of the subunits of adenosine 3':5'-cyclic monophosphate-dependent protein kinase of muscle. Proc Natl Acad Sci U S A (1971) 1.42
Time course of the increase in the myocardial slow inward current after a photochemically generated concentration jump of intracellular cAMP. Proc Natl Acad Sci U S A (1983) 1.41
Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinase. Prog Brain Res (2008) 1.31
Glycogen metabolism in the liver of the foetal rat. Biochem J (1974) 1.29
Glycogen phosphorylase and its converter enzymes in haemolysates of normal human subjects and of patients with type VI glycogen-storage disease. A study of phosphorylase kinase deficiency. Biochem J (1975) 1.20
Immunofluorescent localization of cyclic nucleotide-dependent protein kinases on the mitotic apparatus of cultured cells. J Cell Biol (1980) 1.19
Inhibition of the calcium channel by intracellular protons in single ventricular myocytes of the guinea-pig. J Physiol (1988) 1.19
Regulation by noradrenaline of the mitochondrial and microsomal forms of glycerol phosphate acyltransferase in rat adipocytes. Biochem J (1983) 1.15
Phosphorylation of animal virus proteins by a virion protein kinase. J Virol (1973) 1.15
Cholera toxin activation of adenylate cyclase in cancer cell membrane fragments. Proc Natl Acad Sci U S A (1975) 1.14
Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1988) 1.14
The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Preparation and properties of islet-cell protein phosphokinase. Biochem J (1972) 1.13
Glucose inhibition of epinephrine stimulation of hepatic gluconeogenesis by blockade of the alpha-receptor function. Proc Natl Acad Sci U S A (1974) 1.08
Effect of administration of the fructose on the glycogenolytic action of glucagon. An investigation of the pathogeny of hereditary fructose intolerance. Biochem J (1973) 1.08
Caffeine induces cell death via activation of apoptotic signal and inactivation of survival signal in human osteoblasts. Int J Mol Sci (2008) 1.04
Purification of myosin light chain kinase from bovine cardiac muscle. Proc Natl Acad Sci U S A (1980) 1.03
Nuclear protein kinase activity in glucagon-stimulated perfused rat livers. Biochem J (1974) 1.03
Can phosphorylation of phosphatidate phosphohydrolase by a cyclic AMP-dependent mechanism regulate its activity and subcellular distribution and control hepatic glycerolipid synthesis? Biochem J (1984) 1.03
Activity, expression and function of a second Drosophila protein kinase A catalytic subunit gene. Genetics (1995) 1.00
Protein kinase activity associated with isolated ribosomes from peas and lemna. Plant Physiol (1974) 0.97
Protein kinase activities in rat pancreatic islets of Langerhans. Biochem J (1979) 0.96
Localization of cyclic GMP-dependent protein kinase and substrate in mammalian cerebellum. Proc Natl Acad Sci U S A (1980) 0.96
The effect of streptozotocin-induced diabetes and of insulin supplementation on glycogen metabolism in rat liver. Biochem J (1977) 0.95
In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1978) 0.95
Differential sensitivity to isoprenaline of troponin I and phospholamban phosphorylation in isolated rat hearts. Biochem J (1990) 0.94
Increased expression of the RIalpha subunit of the cAMP-dependent protein kinase A is associated with advanced stage ovarian cancer. Br J Cancer (1999) 0.94
Modulation of cyclic AMP-dependent protein kinase by vasopressin and calcitonin in cultured porcine renal LLC-PK1 cells. Biochem J (1980) 0.93
Differential regulation of bovine brain calmodulin-dependent cyclic nucleotide phosphodiesterase isoenzymes by cyclic AMP-dependent protein kinase and calmodulin-dependent phosphatase. Proc Natl Acad Sci U S A (1985) 0.92
A protein kinase activity tightly associated with Drosophila type II DNA topoisomerase. Proc Natl Acad Sci U S A (1984) 0.92
Adenosine 3':5'-cyclic monophosphate in higher plants: Isolation and characterization of adenosine 3':5'-cyclic monophosphate from Kalanchoe and Agave. Biochem J (1977) 0.91
Comparison of phosphorylation of ribosomal proteins from HeLa and Krebs II ascites-tumour cells by cyclic AMP-dependent and cyclic GMP-dependent protein kinases. Biochem J (1980) 0.91
Isolation of a glycogen synthase I kinase that is independent of adenosine 3':5'-monophosphate. Proc Natl Acad Sci U S A (1975) 0.90
Isolation and some properties of troponin T kinase from rabbit skeletal muscle. Biochem J (1980) 0.90
Reversible inactivation by noradrenaline of long-chain fatty acyl-CoA synthetase in rat adipocytes. Biochem J (1985) 0.89
Inhibition of citrinin-induced apoptotic biochemical signaling in human hepatoma G2 cells by resveratrol. Int J Mol Sci (2009) 0.89
Isoform-specific targeting of PKA to multivesicular bodies. J Cell Biol (2011) 0.89
Chemical and biological methods to detect post-translational modifications of arginine. Biopolymers (2014) 0.88
A pitfall in the interpretation of data on ligand-protein interaction. Biochem J (1975) 0.88
Phosphorylated tau can promote tubulin assembly. Proc Natl Acad Sci U S A (1999) 0.86
Multiple protein kinases from human lymphocytes. Identification enzymes phosphorylating exogenous histon and casein. Biochem J (1975) 0.86
Protein kinase activity in commercially available crystalline yeast alcohol dehydrogenase. Biochem J (1973) 0.85
Adenosine 3':5'-cyclic monophosphate-dependent and plasma-membrane-associated protein kinase(s) from bovine corpus luteum. Biochem J (1975) 0.84
Characterization of Ca2+-activated protein phosphatase activity in exocrine pancreas. Biochem J (1985) 0.83
Monitoring of protein arginine deiminase activity by using fluorescence quenching: multicolor visualization of citrullination. Angew Chem Int Ed Engl (2013) 0.83
The identification and properties of phosphatases in skeletal muscle with activity towards the inhibitory subunit of troponin, and their relationship to other phosphoprotein phosphatases. Biochem J (1976) 0.83
Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII beta regulatory subunit to lose its ability to revert transformed fibroblasts. Proc Natl Acad Sci U S A (1995) 0.83
Ovarian adenosine 3':5'-cyclic monophosphate-dependent protein kinase(s). Regulation by choriogonadotropin and lutropin in rat ovarian cells. Biochem J (1976) 0.82
Purification, characterization and substrate specificity of calmodulin-dependent myosin light-chain kinase from bovine brain. Biochem J (1987) 0.81
Expression, purification, characterization, and deletion mutations of phosphorylase kinase gamma subunit: identification of an inhibitory domain in the gamma subunit. Mol Cell Biochem (1993) 0.79
Evidence for a "mute" catalytic subunit of cyclic AMP-dependent protein kinase from rat muscle and its mode of activation. Proc Natl Acad Sci U S A (1980) 0.79
Changes in microtubule phosphorylation during cell cycle of HeLa cells. Proc Natl Acad Sci U S A (1975) 0.79
Synthesis, transport, and secretion of plasma proteins by the livers of control and Streptococcus pneumoniae-infected rats. Infect Immun (1978) 0.78
Phosphorylase kinase phosphorylation of skeletal-muscle troponin T. Biochem J (1980) 0.78
Photodynamic treatment induces an apoptotic pathway involving calcium, nitric oxide, p53, p21-activated kinase 2, and c-Jun N-terminal kinase and inactivates survival signal in human umbilical vein endothelial cells. Int J Mol Sci (2011) 0.78
Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins. Front Pharmacol (2015) 0.77
A polylysine-induced aggregation of substrate accompanies the stimulation of casein kinase II by polylysine. Biochem J (1993) 0.77
Protein phosphorylation and hydrogen ions modulate calcium-induced closure of gap junction channels. Biophys J (1990) 0.77
Effect of thyroliberin on the concentration of adenosine 3':5'-phosphate and on the activity of adenosine 3':5'-phosphate-dependent protein kinase in prolactin-producing cells in culture. Biochem J (1977) 0.77
A study of 3':5'-cyclic mononucleotide-dependent protein kinase from canine prostate glands. Biochem J (1974) 0.77
Calmodulin-binding proteins and calmodulin-regulated enzymes in dog pancreas. Biochem J (1986) 0.76
Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters. Hum Mol Genet (2013) 0.76
Purification and properties of a nuclear protein kinase from rat mammary gland. Biochem J (1977) 0.75
Activation of Phosphorylase Kinase by Physiological Temperature. Biochemistry (2015) 0.75
Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J Biol Chem (2016) 0.75
Phosphorylation-dephosphorylation of enzymes. Annu Rev Biochem (1979) 11.34
The MAPK signaling cascade. FASEB J (1995) 10.81
An adenosine 3',5'-monophosphate-dependant protein kinase from rabbit skeletal muscle. J Biol Chem (1968) 8.62
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Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases. J Biol Chem (1991) 8.03
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA. Cell (1985) 5.21
Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol (1987) 5.03
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase. J Biol Chem (1977) 4.87
Krebs EG: Purification and characterization of a protein inhibitor of adenosine 3',5'-monophosphate-dependent protein kinases. J Biol Chem (1971) 4.41
Assay of cyclic AMP-dependent protein kinases. Methods Enzymol (1974) 3.84
Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells. J Biol Chem (1990) 3.82
Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. J Biol Chem (1991) 3.81
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. J Biol Chem (1986) 3.49
Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation. Proc Natl Acad Sci U S A (1991) 3.31
Substrate specificity determinants for casein kinase II as deduced from studies with synthetic peptides. J Biol Chem (1987) 3.04
Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. EMBO J (1998) 3.03
Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle. Methods Enzymol (1974) 2.97
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cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family. Proc Natl Acad Sci U S A (1989) 2.95
Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck). Mol Cell Biol (1988) 2.80
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation. Nature (1990) 2.65
Guanosine cyclic 3',5'-phosphate dependent protein kinase, a chimeric protein homologous with two separate protein families. Biochemistry (1984) 2.62
Selective requirement for MAP kinase activation in thymocyte differentiation. Nature (1995) 2.53
Activation of casein kinase II in response to insulin and to epidermal growth factor. Proc Natl Acad Sci U S A (1987) 2.44
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
The genome of Salinibacter ruber: convergence and gene exchange among hyperhalophilic bacteria and archaea. Proc Natl Acad Sci U S A (2005) 2.43
Translational activation of the lck proto-oncogene. Nature (1988) 2.41
Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins. Proc Natl Acad Sci U S A (1989) 2.40
Osteoarthritis, angiogenesis and inflammation. Rheumatology (Oxford) (2004) 2.33
Antibodies to a defined region of pp60src neutralize the tyrosine-specific kinase activity. J Biol Chem (1983) 2.33
Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc Natl Acad Sci U S A (1993) 2.31
Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts. Proc Natl Acad Sci U S A (1999) 2.29
Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells. J Biol Chem (1992) 2.29
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A cyclic AMP--stimulated protein kinase in adipose tissue. Biochem Biophys Res Commun (1969) 2.21
Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1986) 2.20
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Primary-structure requirements for inhibition by the heat-stable inhibitor of the cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1986) 2.14
Characterization of the interaction of a protein inhibitor with adenosine 3',5'-monophosphate-dependent protein kinases. I. Interaction with the catalytic subunit of the protein kinase. J Biol Chem (1972) 2.13
Myc oncoproteins are phosphorylated by casein kinase II. EMBO J (1989) 2.11
Purification and properties of chicken liver D-3-phosphoglycerate dehydrogenase. Biochemistry (1965) 2.08
The regulation of skeletal muscle phosphorylase kinase by Ca2+. J Biol Chem (1971) 2.07
Effects of pulsed ultrasound and temperature on the development of rat embryos in culture. Teratology (1990) 2.07
Rapid membrane effects of steroids in neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene transcription. Endocrinology (1997) 2.05
Evidence for an epidermal growth factor-stimulated protein kinase cascade in Swiss 3T3 cells. Activation of serine peptide kinase activity by myelin basic protein kinases in vitro. J Biol Chem (1990) 2.03
Comparison of adenosine 3':5'-monophosphate-dependent protein kinases from rabbit skeletal and bovine heart muscle. J Biol Chem (1975) 2.03
Activation of skeletal muscle phosphorylase kinase by adenosine triphosphate and adenosine 3',5'-monophosphate. J Biol Chem (1968) 2.03
Identification of the calmodulin-binding domain of skeletal muscle myosin light chain kinase. Proc Natl Acad Sci U S A (1985) 2.00
cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells. Proc Natl Acad Sci U S A (1995) 1.97
Insulin-like growth factor-I and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signaling pathways that are distinct from those of proliferation. J Clin Invest (1994) 1.97
Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathway in NIH/3T3 cells. J Biol Chem (1995) 1.95
Identification of an inhibitory region of the heat-stable protein inhibitor of the cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1985) 1.94
Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase. J Biol Chem (1977) 1.94
Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J Biol Chem (1989) 1.89
Catlysis of the phosphrylaseinase actition reaction. J Biol Chem (1971) 1.89
Optimal spatial requirements for the location of basic residues in peptide substrates for the cyclic AMP-dependent protein kinase. J Biol Chem (1980) 1.88
Progesterone-stimulated meiotic cell division in Xenopus oocytes. Induction by regulatory subunit and inhibition by catalytic subunit of adenosine 3':5'-monophosphate-dependent protein kinase. J Biol Chem (1977) 1.87
Crystallization and properties of rabbit skeletal muscle phosphofructokinase. J Biol Chem (1966) 1.85
The yeast GLC7 gene required for glycogen accumulation encodes a type 1 protein phosphatase. J Biol Chem (1991) 1.85
ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. Proc Natl Acad Sci U S A (1992) 1.83
Regulation of pp56lck during T-cell activation: functional implications for the src-like protein tyrosine kinases. EMBO J (1987) 1.80
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Covalently bound myristate in a lymphoma tyrosine protein kinase. Proc Natl Acad Sci U S A (1984) 1.76
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Measurement of cyclic 3',5'-denosine monophosphate by the activation of skeletal muscle protein kinase. J Biol Chem (1971) 1.72
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Activation of multiple protein kinases during the burst in protein phosphorylation that precedes the first meiotic cell division in Xenopus oocytes. J Biol Chem (1988) 1.69
Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal. J Biol Chem (1990) 1.68
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Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action. Proc Natl Acad Sci U S A (1997) 1.56
Phosphorylation of Avena phytochrome in vitro as a probe of light-induced conformational changes. J Biol Chem (1986) 1.53
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