Published in Am J Pathol on April 01, 1974
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Generation of defective virus after infection of newborn rats with reovirus. J Virol (1976) 1.11
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Comparison of subacute sclerosing panencephalitis and measles viruses: an electron microscope study. J Virol (1971) 1.61
Temperature-sensitive mutants of reovirus type 3 features of genetic recombination. Virology (1971) 1.53
Electron microscopy of measles virus replication. J Virol (1969) 1.53
Genetic manipulation of reovirus--a model for modification of disease. N Engl J Med (1972) 1.53
Temperature-sensitive mutants of reovirus type 3: defects in viral maturation as studied by immunofluorescence and electron microscopy. Virology (1971) 1.50
Hydrocephalus in hamsters, ferrets, rats, and mice following inoculations with reovirus type I. II. Pathologic studies. Lab Invest (1969) 1.47
Ultrastructure of measles virus in cultures of hamster cerebellum. J Virol (1969) 1.42
Experimental subacute sclerosing panencephalitis in the hamster: correlation of age with chronic inclusion-cell encephalitis. J Infect Dis (1972) 1.41
Reovirus type 3 encephalitis--a virologic and ultrastructural study. J Neuropathol Exp Neurol (1973) 1.36
Congenital rubella: the significance of virus persistence. Prog Med Virol (1968) 1.33
Hydrocephalus in hamsters, ferrets, rats, and mice following inoculations with reovirus type I. I. Virologic studies. Lab Invest (1969) 1.23
Temperature-sensitive mutants of reovirus type 3: studies on the synthesis of viral peptides. Virology (1972) 1.20
Neurotropic properties of measles virus in hamsters and mice. J Infect Dis (1971) 1.16
Reovirus type 3 encephalitis: observations of virus-cell interactions in neural tissues. II. Electron microscopic studies. Lab Invest (1971) 1.13
Reovirus type 3 encephalitis: observations of virus-cell interactions in neural tissues. I. Light microscopy studies. Lab Invest (1971) 1.09
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Virus-like structure in multiple sclerosis. Lancet (1973) 1.07
Epstein-Barr virus and Guillain-Barré syndrome. Lancet (1972) 1.03
Adaptation to hamsters of neurotropic measles virus from subacute sclerosing panencephalitis. Nature (1970) 1.01
Acute multiple sclerosis. Confirmation of "paramyxovirus-like" intranuclear inclusions. Arch Neurol (1974) 1.00
Subacute sclerosing panencephalitis virus in cultures of organized central nervous tissue. Lab Invest (1973) 0.99
Experimental measles encephalitis in normal and cyclophosphamide-treated rhesus monkeys. J Infect Dis (1972) 0.96
Mumps virus encephalitis in the hamster. Studies of the inflammatory response and noncytopathic infection of neurons. J Neuropathol Exp Neurol (1968) 0.96
Subacute sclerosing panencephalitis (SSPE) agent in hamsters. I. Acute giant cell encephalitis in newborn animals. Exp Mol Pathol (1971) 0.95
Neural tube defects of chick embryos: an indirect result of influenza A virus infection. J Neuropathol Exp Neurol (1971) 0.92
Reovirus-induced aqueductal stenosis in hamsters. Phase contrast and electron microscopic studies. Lab Invest (1972) 0.87
Neurotropic viruses and the developing brain. N Y State J Med (1973) 0.80
Virus-host cell relationships in measles-infected cultures of central nervous tissue. J Neuropathol Exp Neurol (1972) 0.80
Sigma 1 protein of mammalian reoviruses extends from the surfaces of viral particles. J Virol (1988) 4.77
Molecular basis of reovirus virulence: role of the S1 gene. Proc Natl Acad Sci U S A (1977) 3.97
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Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing). J Virol (1988) 3.84
Isolation and preliminary genetic and biochemical characterization of temperature-sensitive mutants of reovirus. Virology (1969) 3.66
Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat Med (1999) 3.66
Intracellular digestion of reovirus particles requires a low pH and is an essential step in the viral infectious cycle. J Virol (1987) 3.65
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Absolute linkage of virulence and central nervous system cell tropism of reoviruses to viral hemagglutinin. J Infect Dis (1980) 3.27
Intestinal M cells: a pathway for entry of reovirus into the host. Science (1981) 3.23
Glutamate excitotoxicity in a model of multiple sclerosis. Nat Med (2000) 3.20
T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. Science (1994) 3.00
Multiple sclerosis: distribution of T cell subsets within active chronic lesions. Science (1983) 2.91
Observations on viral demyelinating encephalomyelitis. Canine distemper. Lab Invest (1972) 2.88
Adrenoleukodystrophy. A clinical and pathological study of 17 cases. Arch Neurol (1975) 2.86
Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1. J Immunol (1991) 2.80
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Distinct pathways of viral spread in the host determined by reovirus S1 gene segment. Science (1986) 2.61
The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol (1995) 2.57
Evidence for functional domains on the reovirus type 3 hemagglutinin. Virology (1982) 2.55
Neutralization of reovirus: the gene responsible for the neutralization antigen. J Exp Med (1977) 2.53
Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease. J Exp Med (1997) 2.51
Genetics of reovirus: identification of the ds RNA segments encoding the polypeptides of the mu and sigma size classes. Virology (1978) 2.51
Host restriction of Friend leukemia virus. Role of the viral outer coat. Proc Natl Acad Sci U S A (1973) 2.44
Proteolytic digestion of reovirus in the intestinal lumens of neonatal mice. J Virol (1989) 2.38
Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody action. J Virol (1991) 2.37
Activation and characterization of the reovirus transcriptase: genetic analysis. J Virol (1982) 2.36
Molecular basis of reovirus virulence. Role of the M2 gene. J Exp Med (1980) 2.32
Late complications of immune deviation therapy in a nonhuman primate. Science (1996) 2.30
A carboxy-terminal fragment of protein mu 1/mu 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetration. J Virol (1992) 2.29
Identification of the gene coding for the hemagglutinin of reovirus. Virology (1978) 2.28
Isolation of an HTLV-1-like retrovirus from patients with tropical spastic paraparesis. Nature (1988) 2.27
Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J Immunol (2001) 2.27
Role of the host cell in persistent viral infection: coevolution of L cells and reovoirus during persistent infection. Cell (1981) 2.23
Intracellular synthesis of measles virus-specified polypeptides. J Virol (1978) 2.21
Polymorphism of the migration of double-stranded RNA genome segments of reovirus isolates from humans, cattle, and mice. J Virol (1979) 2.15
Identification of attenuating mutations on the reovirus type 3 S1 double-stranded RNA segment with a rapid sequencing technique. J Virol (1986) 2.15
Electron microscopic observations on the cerebellar cortex in kuru. J Neurol Sci (1969) 2.14
Characterization of a zinc blotting technique: evidence that a retroviral gag protein binds zinc. Proc Natl Acad Sci U S A (1988) 2.13
Attenuated reovirus type 3 strains generated by selection of haemagglutinin antigenic variants. Nature (1982) 2.11
Mammalian reoviruses contain a myristoylated structural protein. J Virol (1991) 2.09
Reovirus inhibition of cellular RNA and protein synthesis: role of the S4 gene. Virology (1982) 2.08
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Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest (1991) 2.01
Reovirus M2 gene is associated with chromium release from mouse L cells. J Virol (1993) 1.99
Distinct binding sites for zinc and double-stranded RNA in the reovirus outer capsid protein sigma 3. Mol Cell Biol (1988) 1.96
Determinants of reovirus interaction with the intestinal M cells and absorptive cells of murine intestine. Gastroenterology (1983) 1.95
Sequence of reovirus haemagglutinin predicts a coiled-coil structure. Nature (1985) 1.95
Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice. Nature (1984) 1.95
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GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron (1996) 1.91
Detection of human T-lymphotropic virus type I (HTLV-I) tax RNA in the central nervous system of HTLV-I-associated myelopathy/tropical spastic paraparesis patients by in situ hybridization. Ann Neurol (1995) 1.91
The so-called "Paracolon" bacteria. A bacteriologic and clinical reappraisal. Am J Med (1967) 1.88
A genetic map of reovirus. II. Assignment of the double-stranded RNA-negative mutant groups C, D, and E to genome segments. Virology (1978) 1.87
Anti-tumor necrosis factor therapy abrogates autoimmune demyelination. Ann Neurol (1991) 1.84
Genetic studies on the mechanism of chemical and physical inactivation of reovirus. J Gen Virol (1982) 1.84
Biology of disease. Analysis of autoimmune demyelination: its impact upon multiple sclerosis. Lab Invest (1984) 1.83
Hemagglutinin variants of reovirus type 3 have altered central nervous system tropism. Science (1983) 1.82
Binding and transepithelial transport of immunoglobulins by intestinal M cells: demonstration using monoclonal IgA antibodies against enteric viral proteins. J Cell Biol (1989) 1.82
Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol (2001) 1.78
Temperature-sensitive mutants of reovirus type 3: studies on the synthesis of viral RNA. Virology (1972) 1.77
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A genetic map of reovirus. 1. Correlation of genome RNAs between serotypes 1, 2, and 3. Virology (1978) 1.72
Structure of the reovirus cell-attachment protein: a model for the domain organization of sigma 1. J Virol (1990) 1.71
Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor. J Immunol (1990) 1.71
Molecular basis of reovirus neurovirulence: role of the M2 gene in avirulence. Proc Natl Acad Sci U S A (1982) 1.71
Isolation and biochemical characterization of the mammalian reovirus type 3 cell-surface receptor. Proc Natl Acad Sci U S A (1985) 1.70
Molecular structure of the cell-attachment protein of reovirus: correlation of computer-processed electron micrographs with sequence-based predictions. J Virol (1990) 1.69
Colocalization of lymphocytes bearing gamma delta T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis. Proc Natl Acad Sci U S A (1991) 1.65
Growth and survival of reovirus in intestinal tissue: role of the L2 and S1 genes. J Virol (1989) 1.64
Ion channels induced in lipid bilayers by subvirion particles of the nonenveloped mammalian reoviruses. Proc Natl Acad Sci U S A (1993) 1.64
Identification of a hemagglutinin-specific idiotype associated with reovirus recognition shared by lymphoid and neural cells. J Exp Med (1982) 1.64
The sigma 1 protein determines the extent of spread of reovirus from the gastrointestinal tract of mice. Virology (1983) 1.63
Direct spread of reovirus from the intestinal lumen to the central nervous system through vagal autonomic nerve fibers. Proc Natl Acad Sci U S A (1991) 1.60
Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis. Ann Neurol (1993) 1.58
Role of the mu 1 protein in reovirus stability and capacity to cause chromium release from host cells. J Virol (1996) 1.58
A sigma 1 region important for hemagglutination by serotype 3 reovirus strains. J Virol (1990) 1.57
Identification of a new polypeptide coded by reovirus gene S1. J Virol (1985) 1.57
Why the smallpox virus stocks should not be destroyed. Science (1993) 1.56
On the presence of Ia-positive endothelial cells and astrocytes in multiple sclerosis lesions and its relevance to antigen presentation. J Neuroimmunol (1985) 1.56
Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal mice. J Virol (1990) 1.56
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Protective anti-reovirus monoclonal antibodies and their effects on viral pathogenesis. J Virol (1993) 1.55
The interaction of mammalian reoviruses with the cytoskeleton of monkey kidney CV-1 cells. Virology (1982) 1.55
Temperature-sensitive mutants of reovirus type 3 features of genetic recombination. Virology (1971) 1.53
On the development of CNS lesions in natural canine distemper encephalomyelitis. J Neurol Sci (1976) 1.53
Multiple sclerosis: Fas signaling in oligodendrocyte cell death. J Exp Med (1996) 1.53
Genetic manipulation of reovirus--a model for modification of disease. N Engl J Med (1972) 1.53
The reovirus M1 gene, encoding a viral core protein, is associated with the myocarditic phenotype of a reovirus variant. J Virol (1989) 1.52
Immune response in subacute sclerosing panencephalitis: reduced antibody response to the matrix protein of measles virus. J Immunol (1979) 1.52
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Crystallization of the reovirus type 3 Dearing core. Crystal packing is determined by the lambda 2 protein. J Mol Biol (1990) 1.51
Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells. Science (1983) 1.50