Published in J Cell Biol on June 01, 1965
Biogenesis of endoplasmic reticulum membranes. II. Synthesis of constitutive microsomal enzymes in developing rat hepatocyte. J Cell Biol (1966) 3.62
Comparison of rat liver mitochondrial and microsomal membrane proteins. Proc Natl Acad Sci U S A (1969) 2.48
Correlated morphometric and biochemical studies on the liver cell. II. Effects of phenobarbital on rat hepatocytes. J Cell Biol (1969) 2.41
The rubella virus E1 glycoprotein is arrested in a novel post-ER, pre-Golgi compartment. J Cell Biol (1992) 2.00
Analytical study of microsomes and isolated subcellular membranes from rat liver. II. Preparation and composition of the microsomal fraction. J Cell Biol (1974) 1.95
Phenobarbital-induced fine structural changes in rat liver. Am J Pathol (1966) 1.80
Nuclear membranes from mammalian liver. I. Isolation procedure and general characterization. J Cell Biol (1970) 1.67
Biosynthesis of microsomal nicotinamide-adenine dinucleotide phosphate-cytochrome c reductase by membrane-bound and free polysomes from rat liver. Biochem J (1969) 1.62
Properties of the System for the Mixed Function Oxidation of Kaurene and Kaurene Derivatives in Microsomes of the Immature Seed of Marah macrocarpus: Electron Transfer Components. Plant Physiol (1976) 1.51
Enzyme-membrane relationship in phenobarbital induction of synthesis of drug-metabolizing enzyme system and proliferation of endoplasmic membranes. J Cell Biol (1966) 1.48
Time Course of Induction of Cytochrome P-450, NADPH-Cytochrome c Reductase, and Cinnamic Acid Hydroxylase by Phenobarbital, Ethanol, Herbicides, and Manganese in Higher Plant Microsomes. Plant Physiol (1980) 1.46
Effect of sodium phenobarbital on bilirubin metabolism in an infant with congenital, nonhemolytic, unconjugated hyperbilirubinemia, and kernicterus. J Clin Invest (1969) 1.42
Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver. J Cell Biol (1987) 1.30
Heterogeneous distribution of enzymes in submicrosomal membrane fragments. J Cell Biol (1969) 1.26
An integrated functional genomic study of acute phenobarbital exposure in the rat. BMC Genomics (2010) 1.19
The properties of hydrogen peroxide production under hyperoxic and hypoxic conditions of perfused rat liver. Biochem J (1975) 1.19
Identification of the sequences in HMG-CoA reductase required for karmellae assembly. Mol Biol Cell (1995) 1.18
Primate biliary physiology. 8. The effect of phenobarbital upon bile salt synthesis and pool size, biliary lipid secretion, and bile composition. J Clin Invest (1973) 1.16
Effects of diet and microsomal enzyme induction on the toxicity of dimethyl nitrosamine. Br J Exp Pathol (1969) 1.14
Studies on the lipid composition of the rat liver endoplasmic reticulum after induction with phenobarbitone and 20-methylcholanthrene. Biochem J (1974) 1.11
The alteration of superoxide dismutase, catalase, glutathione peroxidase, and NAD(P)H cytochrome c reductase in guinea pig polymorphonuclear leukocytes and alveolar macrophages during hyperoxia. J Clin Invest (1976) 1.10
Expression of the 180-kD ribosome receptor induces membrane proliferation and increased secretory activity in yeast. J Cell Biol (1999) 1.10
Heterogeneous distribution of glucose 6-phosphatase in rat liver microsomal fractions as shown by adaptation of a cytochemical technique. Biochem J (1973) 1.08
Immunoelectron microscope localization of cytochrome P-450 on microsomes and other membrane structures of rat hepatocytes. J Cell Biol (1978) 1.08
Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein. Proc Natl Acad Sci U S A (2011) 1.07
Increase in levels of glucuronylating enzymes and associated rise in activities of mitochondrial oxidative enzymes upon phenobarbital administration in the rat. J Cell Biol (1967) 1.06
Mechanism of the cation effect in subfractionation of microsomes. J Cell Biol (1966) 1.05
Turnover of mammalian phospholipids. Rates of turnover and metabolic heterogeneity in cultured human lymphocytes and in tissues of healthy, starved and vitamin A-deficient rats. Biochem J (1970) 1.03
Isolation of centrolobular and perilobular hepatocytes after phenobarbital treatment. J Cell Biol (1975) 1.00
Inhibition of gluconeogenesis in isolated rat hepatocytes after chronic treatment with phenobarbital. Biochem J (1991) 0.99
A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum. Cell Death Differ (2012) 0.98
The morphologic effects of dieldrin and methyl mercuric chloride on pars recta segments of rat kidney proximal tubules. Am J Pathol (1972) 0.93
Phenobarbital regulates nuclear expression of HNF-4alpha in mouse and rat hepatocytes independent of CAR and PXR. Hepatology (2006) 0.90
Apocytochrome P-450: reconstitution of functional cytochrome with hemin in vitro. Proc Natl Acad Sci U S A (1975) 0.89
Acute effects of 3'-methyl-4-dimethylaminoazobenzene intoxication on rat liver. Structural and functional changes in the endoplasmic reticulum and NADPH-related electron transport. Am J Pathol (1968) 0.86
Biochemical effects of the porphyrinogenic drug allylisopropylacetamide. A comparative study with phenobarbital. Biochem J (1973) 0.86
Studies on the biogenesis of smooth endoplasmic reticulum membranes in hepatocytes of phenobarbital-treated rats. II. The site of phospholipid synthesis in the initial phase of membrane proliferation. J Cell Biol (1974) 0.85
Phospholipid asymmetry in rough- and smooth-endoplasmic-reticulum membranes of untreated and phenobarbital-treated rat liver. Biochem J (1980) 0.85
Cytoplasmic effects of cortisol in liver. Biochem J (1969) 0.82
On the relationship of liver glucose-6-phosphatase to the proliferation of endoplasmic reticulum in phenobarbital induction. J Cell Biol (1966) 0.82
Induction by phenobarbital of the mRNA for a specific variant of rat liver microsomal cytochrome P-450. Biochem J (1981) 0.82
Regeneration of the mammalian liver. VI. Retention of phenobarbital-induced cytoplasmic alterations in dividing hepatocytes. Am J Pathol (1968) 0.82
Hg2 plus-induced kidney necrosis. Subcellular localization and structure-linked lysosomal enzyme changes. Am J Pathol (1970) 0.81
Quantification of NADPH: cytochrome P-450 reductase in liver microsomes by a specific radioimmunoassay technique. Biochem J (1983) 0.81
The fine structure of proliferating cartilage cells: structural changes in an experimental model. J Anat (1975) 0.80
Diverse mechanisms of hepatocellular injuries due to chemicals: evidence in rats administered carbon tetrachloride or dimethylnitrosamine. Br J Exp Pathol (1975) 0.79
Interaction of chemical carcinogens and drug-metabolizing enzymes in primary cultures of hepatic cells from the rat. Am J Pathol (1976) 0.79
The effect of phenobarbitone on protein synthesis by liver polyribosomes in fed and starved rats. Biochem J (1975) 0.78
Phospholipid synthesis in rat liver endoplasmic reticulum after the administration of phenobarbitone and 20-methylcholanthrene. Biochem J (1974) 0.78
ER reorganization is remarkably induced in COS-7 cells accumulating transmembrane protein receptors not competent for export from the endoplasmic reticulum. J Membr Biol (2014) 0.77
Manganese-enhanced biotransformation of atrazine by the white rot fungus Pleurotus pulmonarius and its correlation with oxidation activity. Appl Environ Microbiol (1996) 0.77
Effects of starvation on the hepatotoxicity of carbon tetrachloride. A light and electron microscopic study. Am J Pathol (1966) 0.77
Effect of phenobarbitone on the nucleocytoplasmic transport of ribonucleic acid in vitro. Biochem J (1976) 0.76
STUDIES ON THE BIOGENESIS OF SMOOTH ENDOPLASMIC RETICULUM MEMBRANES IN LIVERS OF PHENOBARBITAL-TREATED RATS : I. The Site of Activity of Acyltransferases Involved in Synthesis of the Membrane Phospholipid. J Cell Biol (1972) 0.76
Recollection of the early years of the research on cytochrome P450. Proc Jpn Acad Ser B Phys Biol Sci (2011) 0.76
Influence of phenobarbitone on liver regeneration and microsomal N-demethylating activity in partially hepatectomized rats. Br J Pharmacol (1971) 0.75
ON THE MECHANISM OF DRUG HYDROXYLATION IN RAT LIVER MICROSOMES. J Cell Biol (1965) 0.75
[Various forms of endoplasmic reticulum in dedifferenciated keratinocytes. Observations in squamous cell carcinoma]. Arch Dermatol Forsch (1972) 0.75
Induction and repression of the major phenobarbital-induced cytochrome P-450 measured by radioimmunoassay. Biochem J (1983) 0.75
Mechanisms and consequences of the induction of microsomal enzymes of mammalian liver. Biochem J (1972) 0.75
Phenobarbital-induced, membrane-like scrolls in the oenocytes of Musca domestica linnaeus. J Cell Biol (1973) 0.75
Dynamics of injury and repair in hepatic cells. II. Association of membranes with lipid during recovery from ethionine-induced fatty liver. Am J Pathol (1971) 0.75
The effect of phenobarbital on cholesterol gallstones in hamsters. Gut (1973) 0.75
Ultrastructural changes in hepatocytes induced by pregnenolone-16a-carbonitrile (PCN). Can J Comp Med (1972) 0.75
Ultrastructural Characterization of Membrane Rearrangements Induced by Porcine Epidemic Diarrhea Virus Infection. Viruses (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem (1957) 173.99
The colorimetric determination of phosphorus. Biochem J (1932) 116.02
Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol (1961) 113.20
Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol (1961) 65.10
Simple methods for "staining with lead" at high pH in electron microscopy. J Biophys Biochem Cytol (1961) 50.33
Liver microsomes; an integrated morphological and biochemical study. J Biophys Biochem Cytol (1956) 19.70
The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. Biochem J (1953) 13.87
The role of deoxyribonucleic acid in ribonucleic acid synthesis. III. The inhibition of the enzymatic synthesis of ribonucleic acid and deoxyribonucleic acid by actinomycin D and proflavin. Proc Natl Acad Sci U S A (1962) 11.58
zeta-Collidine as a basis for buffering fixatives. J Biophys Biochem Cytol (1959) 10.95
Determination of nucleic acids in animal tissues. J Biol Chem (1955) 9.56
Actionmycin D inhibition of deoxyribonucleic acid-dependent synthesis of ribonucleic acid. Science (1962) 4.64
Enzymatic adaptation in bacteria. Annu Rev Microbiol (1951) 4.28
Hepatic triphosphopyridine nucleotide-cytochrome c reductase: isolation, characterization, and kinetic studies. J Biol Chem (1962) 4.15
Microsomal triphosphopyridine nucleotide-cytochrome c reductase of liver. J Biol Chem (1962) 3.62
Substrate-induced synthesis and other properties of benzpyrene hydroxylase in rat liver. J Biol Chem (1957) 3.05
The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen. J Pharmacol Exp Ther (1957) 2.46
Pigments of rat liver microsomes. Arch Biochem Biophys (1958) 2.37
Enzymatic metabolism of drugs and other foreign compounds. Annu Rev Biochem (1958) 2.36
Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs. J Pharmacol Exp Ther (1960) 2.04
INSULIN-DEPENDENT SYNTHESIS OF LIVER GLUCOKINASE IN THE RAT. J Biol Chem (1963) 2.03
DRUG-INDUCED CHANGES IN THE LIVER ENDOPLASMIC RETICULUM: ASSOCIATION WITH DRUG-METABOLIZING ENZYMES. Science (1963) 2.02
Reconstruction of oxidative phosphorylation in aged mitochondrial systems. Exp Cell Res (1955) 1.81
Inhibition of the TPNH-linked lipid peroxidation of liver microsomes by drugs undergoing oxidative demethylation. Biochem Biophys Res Commun (1964) 1.73
ELECTRON MICROSCOPIC STUDIES OF THE EPITHELIUM OF THE PROXIMAL TUBULE OF THE RAT KIDNEY. I. THE INTRACELLULAR LOCALIZATION OF ACID PHOSPHATASE. Lab Invest (1964) 1.60
PUROMYCIN INHIBITION OF ENZYME INDUCTION BY 3-METHYLCHOLANTHRENE AND PHENOBARBITAL. J Biol Chem (1963) 1.44
[Enzyme induction and increase of endoplasmic reticulum in liver cells during phenobarbital (Luminal) therapy]. Klin Wochenschr (1963) 1.40
THE STIMULATORY EFFECT OF 3-METHYLCHOLANTHRENE ON MICROSOMAL AMINO ACID INCORPORATION AND BENZPYRENE HYDROXYLASE ACTIVITY AND ITS INHIBITION BY ACTINOMYCIN D. Biochim Biophys Acta (1963) 1.36
Mechanism of puromycin inhibition of hemoglobin synthesis. Biochem Biophys Res Commun (1962) 1.23
Phenobarbital-induced synthesis of the oxidative demethylating enzymes of rat liver microsomes. Biochem Biophys Res Commun (1964) 1.21
Effects of 3-methylcholanthrene and phenobarbital on amino acid incorporation into protein. Science (1961) 1.01
Increased activity of microsomal strychnine-metabolizing enzyme induced by phenobarbital and other drugs. Biochem Pharmacol (1962) 0.85
An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study. J Cell Biol (1967) 12.04
Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron (1995) 4.07
Calcium-activated DNA fragmentation kills immature thymocytes. FASEB J (1989) 3.26
Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration. Arch Biochem Biophys (1989) 3.07
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The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells. J Biol Chem (1982) 2.81
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Subfractionation and composition of microsomal membranes: a review. J Histochem Cytochem (1968) 2.46
Flavoproteins of the mitochondrial respiratory chain. Proc Natl Acad Sci U S A (1967) 2.40
CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis. J Biol Chem (1996) 2.40
Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells. EMBO J (1999) 2.36
Substrate-induced synthesis of the hydroxylating enzyme system of liver microsomes. Fed Proc (1966) 2.36
Role of Ca2+ in toxic cell killing. Trends Pharmacol Sci (1989) 2.17
The oxidative inactivation of mitochondrial electron transport chain components and ATPase. J Biol Chem (1990) 2.08
Injected cytochrome c induces apoptosis. Nature (1998) 2.05
Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines. J Biol Chem (1994) 2.04
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Enzyme topology of intracellular membranes. Annu Rev Biochem (1977) 2.01
Quinone-responsive multiple respiratory-chain dysfunction due to widespread coenzyme Q10 deficiency. Lancet (2000) 2.00
Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complex. J Immunol (1989) 1.98
2,5-Di-(tert-butyl)-1,4-benzohydroquinone rapidly elevates cytosolic Ca2+ concentration by mobilizing the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool. J Biol Chem (1989) 1.96
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Ultrastructural studies on prostatic involution in the rat. Mechanism of autophagy in epithelial cells, with special reference to the rough-surfaced endoplasmic reticulum. J Ultrastruct Res (1971) 1.90
2,5-Di(tert-butyl)-1,4-benzohydroquinone--a novel inhibitor of liver microsomal Ca2+ sequestration. FEBS Lett (1987) 1.90
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Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis. J Biol Chem (1996) 1.88
Spermine prevents endonuclease activation and apoptosis in thymocytes. Exp Cell Res (1991) 1.87
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The role of calcium in apoptosis. Cell Calcium (1998) 1.84
Calcium-mediated mechanisms in chemically induced cell death. Annu Rev Pharmacol Toxicol (1992) 1.82
Observations on the application to electron microscopy on the lead phosphate technique for the demonstration of acid phosphatase. Histochemie (1965) 1.81
The osteoclast: review of ultrastructure, origin, and structure-function relationship. Clin Orthop Relat Res (1976) 1.80
Studies on induced cellular autophagy. I. Electron microscopy of cells with in vivo labelled lysosomes. Exp Cell Res (1969) 1.80
2,3,7,8-Tetrachlorodibenzo-p-dioxin kills immature thymocytes by Ca2+-mediated endonuclease activation. Science (1988) 1.79
Lysosomal changes during castration-induced prostatic involution in the rat. Acta Pathol Microbiol Scand A (1970) 1.78
Evidence for the involvement of iron in the ADP-activated peroxidation of lipids in microsomes and mitochondria. Biochem Biophys Res Commun (1964) 1.75
The relationship between the structure and activity of rat skeletal muscle mitochondria after thyroidectomy and thyroid hormone treatment. J Cell Biol (1965) 1.75
Childhood cancer in Sweden, 1958-1974. I. Incidence and mortality. Acta Paediatr Scand (1978) 1.73
Inhibition of the TPNH-linked lipid peroxidation of liver microsomes by drugs undergoing oxidative demethylation. Biochem Biophys Res Commun (1964) 1.73
Involvement of caspases in neutrophil apoptosis: regulation by reactive oxygen species. Blood (1998) 1.70
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The turnover of radioactive phosphate injected into the subarachnoid space of the brain of the rat. Biochem J (1950) 1.63
Flavoproteins of mitochondrial fatty acid oxidation. Proc Natl Acad Sci U S A (1967) 1.59
Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody. J Biol Chem (1996) 1.58
Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration. J Biol Chem (1998) 1.57
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ATP stimulates Ca2+ uptake and increases the free Ca2+ concentration in isolated rat liver nuclei. Proc Natl Acad Sci U S A (1989) 1.54
Studies with ubiquinone-depleted submitochondrial particles. Essentiality of ubiquinone for the interaction of succinate dehydrogenase, NADH dehydrogenase, and cytochrome b. Eur J Biochem (1969) 1.53
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DT-diaphorase as a quinone reductase: a cellular control device against semiquinone and superoxide radical formation. Arch Biochem Biophys (1982) 1.51
Enzyme-membrane relationship in phenobarbital induction of synthesis of drug-metabolizing enzyme system and proliferation of endoplasmic membranes. J Cell Biol (1966) 1.48
Hsp27 protects mitochondria of thermotolerant cells against apoptotic stimuli. Cell Stress Chaperones (2001) 1.47
Apoptosis induced by a human milk protein. Proc Natl Acad Sci U S A (1995) 1.47
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Evidence for the participation of the Golgi apparatus in the intracellular transport of nascent albumin in the liver cell. J Cell Biol (1970) 1.46
The role of calcium in the regulation of apoptosis. Biochem Biophys Res Commun (1997) 1.45
Studies on the synthesis and intracellular transport of lipoprotein particles in rat liver. J Cell Biol (1975) 1.44
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Bleb formation in hepatocytes during drug metabolism is caused by disturbances in thiol and calcium ion homeostasis. Science (1982) 1.41
Demonstration of nuclear compartmentalization of glutathione in hepatocytes. Proc Natl Acad Sci U S A (1992) 1.40
Regulation of intracellular calcium compartmentation: studies with isolated hepatocytes and t-butyl hydroperoxide. Proc Natl Acad Sci U S A (1982) 1.40
Comparison between the effects of the microsomal Ca(2+)-translocase inhibitors thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone on cellular calcium fluxes. Biochem J (1991) 1.39
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DNA damage induces two distinct modes of cell death in ovarian carcinomas. Cell Death Differ (2007) 1.37
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On the histogenesis of the cells in fracture callus. Electron microscopic autoradiographic observations in parabiotic rats and studies on labeled monocytes. Virchows Arch B Cell Pathol (1973) 1.36
Agents that elevate cAMP stimulate DNA fragmentation in thymocytes. J Immunol (1990) 1.36
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Characterization of rat-liver microsomal glutathione S-transferase activity. Eur J Biochem (1980) 1.30
The metabolism of polycyclic hydrocarbons and its relationship to cancer. Biochim Biophys Acta (1978) 1.30
Biliary tract cancer and occupation in Sweden. Br J Ind Med (1986) 1.30
An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death. Cell Death Differ (2008) 1.29
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Calcium-activated DNA fragmentation in rat liver nuclei. J Biol Chem (1989) 1.27
Heterogeneous distribution of enzymes in submicrosomal membrane fragments. J Cell Biol (1969) 1.26
Studies on induced cellular autophagy. II. Characterization of the membranes bordering autophagosomes in parenchymal liver cells. Exp Cell Res (1969) 1.26
Current approaches to the mechanism of energy-coupling in the respiratory chain. Studies with yeast mitochondria. Bull Soc Chim Biol (Paris) (1966) 1.26
Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system. J Biol Chem (1986) 1.25
Calcineurin and mitochondrial function in glutamate-induced neuronal cell death. FEBS Lett (1996) 1.25
Evidence for the involvement of a glucose-6-phosphate carrier in microsomal glucose-6-phosphatase activity. Eur J Biochem (1978) 1.24
All along the watchtower: on the regulation of apoptosis regulators. FASEB J (1999) 1.24
Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch Biochem Biophys (1984) 1.23
Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper. J Biol Chem (1995) 1.23
Signalling mechanisms and oxidative stress in apoptosis. Toxicol Lett (1995) 1.23
Chelation of intracellular zinc triggers apoptosis in mature thymocytes. Lab Invest (1993) 1.23