Published in J Immunol on November 01, 1974
The enigma of sepsis. J Clin Invest (2003) 4.32
Evidence that the superoxide-generating system of human leukocytes is associated with the cell surface. J Clin Invest (1977) 2.77
Effects of activated complement components on enzyme secretion by macrophages. Immunology (1976) 2.63
Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation. Immunology (1977) 1.82
Increased C5a receptor expression in sepsis. J Clin Invest (2002) 1.79
Roles of B cells in rheumatoid arthritis. Arthritis Res Ther (2003) 1.57
Chemotactic factor inactivation by the myeloperoxidase-hydrogen peroxide-halide system. J Clin Invest (1979) 1.39
New insights of an old defense system: structure, function, and clinical relevance of the complement system. Mol Med (2010) 1.37
A specific inhibitor of complement (C5)-derived chemotactic activity in serum from patients with systemic lupus erythematosus. J Clin Invest (1978) 1.28
Induction of interleukin-8 synthesis from monocytes by human C5a anaphylatoxin. Am J Pathol (1994) 1.28
Macrophage responses to mouldy hay dust, Micropolyspora faeni and zymosan, activators of complement by the alternative pathway. Clin Exp Immunol (1977) 1.21
Complement in ischemia reperfusion injury. Am J Pathol (2003) 1.15
Expression of C5a-like biological activities by the fifth component of human complement (C5) upon limited digestion with noncomplement enzymes without release of polypeptide fragments. J Exp Med (1983) 1.13
Complement bridges between cells analysis of a possible cell-cell interaction mechanism. J Exp Med (1977) 1.08
Production of C2 by human alveolar macrophages. Immunology (1978) 1.04
Fibronectin degradation products containing the cytoadhesive tetrapeptide stimulate human neutrophil degranulation. J Clin Invest (1988) 1.03
Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection. Transplant Rev (Orlando) (2009) 1.03
Circulating complement proteins in patients with sepsis or systemic inflammatory response syndrome. Clin Diagn Lab Immunol (1996) 1.01
Collagen degradation in ischaemic rat hearts. Biochem J (1990) 1.01
Damaged membrane fragments and immune complexes in the blood of patients with Behcet's syndrome. Clin Exp Immunol (1978) 1.01
Investigative studies of the dermatitis caused by the larva of the brown-tail moth, Euproctis chrysorrhoea l. (Lepidoptera, Lymantriidae). IV. Further characterization of skin reactive substances. Arch Dermatol Res (1977) 0.97
Activation of complement in normal serum by hydrogen peroxide and hydrogen peroxide-related oxygen radicals produced by activated neutrophils. Clin Exp Immunol (1992) 0.93
Chemotactic activity generated in human serum from the fifth component of complement by hydrogen peroxide. Am J Pathol (1984) 0.91
Complement activation by cell wall fractions of Micropolyspora faeni. Infect Immun (1978) 0.90
Identification of conformational epitopes for human IgG on Chemotaxis inhibitory protein of Staphylococcus aureus. BMC Immunol (2009) 0.86
Expression and subcellular targeting of human complement factor C5a in Nicotiana species. PLoS One (2012) 0.85
Potentiation of C56-initiated lysis by leucocyte cationic proteins, myelin basic proteins and lysine-rich histones. Immunology (1976) 0.85
A chemotactic inhibitor in synovial fluid. Immunology (1983) 0.84
Current and future concepts of abdominal sepsis. World J Surg (2005) 0.83
Alterations of dendritic cells in sepsis: featured role in immunoparalysis. Biomed Res Int (2015) 0.82
C5a regulates IL-12+ DC migration to induce pathogenic Th1 and Th17 cells in sepsis. PLoS One (2013) 0.82
Innate and adaptive immunologic functions of complement in the host response to Listeria monocytogenes infection. Immunobiology (2016) 0.82
Chemotactic factors released in culture by intact developing and healing skin lesions produced in rabbits by the irritant sulfur mustard. Inflammation (1997) 0.82
Alteration of chemoattractant receptor expression regulates human neutrophil chemotaxis in vivo. Ann Surg (2002) 0.82
Enhancement of in vitro immunoglobulin synthesis of human lymphocytes by lysosomal enzymes from polymorphonuclear leucocytes. Clin Exp Immunol (1977) 0.81
Detection of a complement-derived chemotactic factor for tumor cells in human inflammatory and neoplastic effusions. Am J Pathol (1983) 0.81
Investigative studies of the dermatitis caused by the larva of the brown-tail moth, Euproctis chrysorrhoea l. (Lepidoptera, Lymantriidae). III. Chemical analysis of skin reactive substances. Arch Dermatol Res (1977) 0.80
Defective neutrophil degranulation induced by interleukin-8 and complement 5a and down-regulation of associated receptors in children vertically infected with human immunodeficiency virus type 1. Clin Diagn Lab Immunol (2001) 0.76
Effect of glomerular basement membrane on the initiation of chemiluminescence and lysosomal enzyme release in human polymorphonuclear leucocytes: an in vitro model of glomerular disease. Immunology (1984) 0.76
Proceedings. Site of action of an anti-inflammatory fraction from normal human plasma. Br J Pharmacol (1975) 0.75
The mononuclear phagocytes of the rat adrenal. Am J Pathol (1981) 0.75
Lysosomes and the connective tissue diseases. J Clin Pathol Suppl (R Coll Pathol) (1978) 0.75
Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis. J Clin Invest (1975) 6.25
Mechanisms of lysosomal enzyme release from human leukocytes: microtubule assembly and membrane fusion induced by a component of complement. Proc Natl Acad Sci U S A (1973) 4.58
Studies on lysosomes. XI. Characterization of a hydrolase-rich fraction from human lymphocytes. J Cell Biol (1968) 4.22
Effect of cyclic AMP on release of lysosomal enzymes from phagocytes. Nat New Biol (1971) 4.09
Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function. J Clin Invest (1974) 3.65
Cytochalasin B: effect on lysosomal enzyme release from human leukocytes. Proc Natl Acad Sci U S A (1973) 3.63
Mechanisms of lysosomal enzyme release from leukocytes exposed to immune complexes and other particles. J Exp Med (1971) 3.38
Release of inflammatory mediators from stimulated neutrophils. N Engl J Med (1980) 3.35
Calcium-induced lysozyme secretion from human polymorphonuclear leukocytes. Biochem Biophys Res Commun (1974) 3.24
A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci U S A (1992) 2.79
Evidence that the superoxide-generating system of human leukocytes is associated with the cell surface. J Clin Invest (1977) 2.77
Lysosomal enzyme release from human leukocytes: mediation by the alternate pathway of complement activation. J Immunol (1973) 2.66
Lysosome. N Engl J Med (1965) 2.49
Changes in membrane potential of human granulocytes antecede the metabolic responses to surface stimulation. Proc Natl Acad Sci U S A (1978) 2.33
Mechanisms of lysosomal enzyme release from human leukocytes. I. Effect of cyclic nucleotides and colchicine. J Cell Biol (1973) 2.33
Interaction of alytic polypeptide, melittin, with lipid membrane systems. J Biol Chem (1969) 2.31
Effect of cyclic 3',5'-adenosine monophosphate and theophylline on lymphocyte transformation. Proc Soc Exp Biol Med (1970) 2.30
Tumor necrosis factor provokes superoxide anion generation from neutrophils. Biochem Biophys Res Commun (1986) 2.27
Leukocytic proteases and the immunologic release of lysosomal enzymes. Am J Pathol (1972) 2.26
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med (1983) 2.18
Potassium and amino acid transport in human leukocytes exposed to phagocytic stimuli. J Cell Biol (1974) 2.16
Effects of cholera enterotoxin on adenosine 3',5'-monophosphate and neutrophil function. Comparison with other compounds which stimulate leukocyte adenyl cyclase. J Clin Invest (1973) 2.16
The action of steroids and streptolysin S on the permeability of phospholipid structures to cations. J Mol Biol (1965) 2.10
Concanavalin A induces microtubule assembly and specific granule discharge in human polymorphonuclear leukocytes. J Cell Biol (1976) 2.08
Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro. Biochem Biophys Res Commun (1982) 2.02
Breakdown of cartilage proteinpolysaccharide by lysosomes. Arthritis Rheum (1968) 1.99
Independent effects of IgG and complement upon human polymorphonuclear leukocyte function. J Immunol (1976) 1.97
Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils. J Immunol (1985) 1.96
Lysosomes and joint disease. Arthritis Rheum (1966) 1.90
Phospholipid spherules (liposomes) as a model for biological membranes. J Lipid Res (1968) 1.89
Mechanisms of lysosomal enzyme release from human polymorphonuclear leukocytes. Effects of phorbol myristate acetate. J Cell Biol (1975) 1.87
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol (1992) 1.84
Ceruloplasmin. A scavenger of superoxide anion radicals. J Biol Chem (1979) 1.84
Stimulus response coupling in the human neutrophil. II. Temporal analysis of changes in cytosolic calcium and calcium efflux. J Biol Chem (1984) 1.84
The adhesion molecules of inflammation. Arthritis Rheum (1993) 1.83
Lysosomal mechanisms of tissue injury in arthritis. N Engl J Med (1972) 1.81
The role of lysosomes in inflammation and disease. Annu Rev Med (1967) 1.76
Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells. J Clin Invest (1986) 1.76
A general method for the introduction of enzymes, by means of immunoglobulin-coated liposomes, into lysosomes of deficient cells. Proc Natl Acad Sci U S A (1975) 1.76
Degranulation, membrane addition, and shape change during chemotactic factor-induced aggregation of human neutrophils. J Cell Biol (1982) 1.75
Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils. Science (1993) 1.72
Role of microtubule assembly in lysosomal enzyme secretion from human polymorphonuclear leukocytes. A reevaluation. J Cell Biol (1977) 1.69
Leukotriene B4 is a complete secretagogue in human neutrophils: a kinetic analysis. Biochem Biophys Res Commun (1982) 1.69
Reciprocal effects of cAMP and cGMP on microtubule-dependent release of lysosomal enzymes. Ann N Y Acad Sci (1975) 1.68
The action of polyene antibiotics on phospholipid-cholesterol structures. J Biol Chem (1967) 1.67
The roles of extracellular and intracellular calcium in lysosomal enzyme release and superoxide anion generation by human neutrophils. Biochim Biophys Acta (1981) 1.65
Crystal deposition disease. Diagnosis by electron microscopy. Am J Med (1977) 1.63
The mechanisms of action of nonsteroidal antiinflammatory drugs. Arthritis Rheum (1989) 1.63
Sudden blindness in acute pancreatitis. Possible role of complement-induced retinal leukoembolization. Arch Intern Med (1981) 1.62
Incorporation of lysozyme into liposomes. A model for structure-linked latency. J Biol Chem (1970) 1.62
Protected environments and prophylactic antibiotics. A prospective controlled study of their utility in the therapy of acute leukemia. N Engl J Med (1973) 1.61
Molecular basis of gouty inflammation: interaction of monosodium urate crystals with lysosomes and liposomes. Nat New Biol (1972) 1.59
Phosphatidate and oxidized fatty acids are calcium ionophores. Studies employing arsenazo III in liposomes. J Biol Chem (1981) 1.59
Studies on lysosomes. XII. Redistribution of acid hydrolases in human lymphocytes stimulated by phytohemagglutinin. J Cell Biol (1968) 1.58
Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. J Exp Med (1978) 1.57
Dissociation between increased surface expression of gp165/95 and homotypic neutrophil aggregation. J Immunol (1988) 1.56
Arthritis induced in rabbits by lysates of granulocyte lysosomes. Arthritis Rheum (1969) 1.55
Stimulus response coupling in the human neutrophil. I. Kinetic analysis of changes in calcium permeability. J Biol Chem (1984) 1.52
C-reactive protein in systemic lupus erythematosus. Arthritis Rheum (1977) 1.52
The role of lysosomes in immune responses. Adv Immunol (1970) 1.47
Characterization of a neutral protease from lysosomes of rabbit polymorphonuclear leucocytes. Biochem J (1971) 1.45
Effects of indomethacin, 5,8,11,14-eicosatetraynoic acid, and p-bromophenacyl bromide on lysosomal enzyme release and superoxide anion generation by human polymorphonuclear leukocytes. Biochem Pharmacol (1980) 1.44
Omega-oxidation is the major pathway for the catabolism of leukotriene B4 in human polymorphonuclear leukocytes. J Biol Chem (1984) 1.44
Enhancement of nitroblue tetrazolium dye reduction by leukocytes exposed to a component of complement in the absence of phagocytosis. J Immunol (1975) 1.43
Influence of divalent cations upon complement-mediated enzyme release from human polymorphonuclear leukocytes. J Immunol (1975) 1.43
Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways. Proc Natl Acad Sci U S A (1991) 1.43
Preconditioning provides complete protection against retinal ischemic injury in rats. Invest Ophthalmol Vis Sci (1998) 1.43
Up-regulation of the iC3b receptor (CR3) is neither necessary nor sufficient to promote neutrophil aggregation. J Clin Invest (1988) 1.42
An abnormality of the gene that encodes neutrophil Fc receptor III in a patient with systemic lupus erythematosus. J Clin Invest (1990) 1.41
Gastrointestinal "sterilization" in the treatment of patients with acute leukemia. Cancer (1970) 1.39
Increased levels of cyclic adenosine-3',5'-monophosphate in human polymorphonuclear leukocytes after surface stimulation. J Clin Invest (1980) 1.36
Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB. Proc Natl Acad Sci U S A (1999) 1.36
Influence of local anesthetics upon human polymorphonuclear leukocyte function in vitro. Reduction of lysosomal enzyme release and superoxide anion production. J Exp Med (1977) 1.36
Stimulus-response coupling in the human neutrophil. Transmembrane potential and the role of extracellular Na+. Biochim Biophys Acta (1980) 1.35
Appearance of hydrolase rich granules in human lymphocytes induced by phytohemagglutinin and antigens. Blood (1967) 1.35
Increased levels of plasma anaphylatoxins in systemic lupus erythematosus predict flares of the disease and may elicit vascular injury in lupus cerebritis. Arthritis Rheum (1988) 1.34
Colloidal lanthanum as a marker for impaired plasma membrane permeability in ischemic dog myocardium. Am J Pathol (1975) 1.33
Constitutive and induced phosphorylation of the alpha- and beta-chains of the CD11/CD18 leukocyte integrin family. Relationship to adhesion-dependent functions. J Immunol (1990) 1.32
Staphylococcal alpha-toxin: effects on artificial lipid spherules. Science (1966) 1.32
Membrane perturbation: studies employing a calcium-sensitive dye, arsenazo III, in liposomes. Proc Natl Acad Sci U S A (1976) 1.31
Effects of four components of the polyene antibiotic, filipin, on phospholipid spherules (liposomes) and erythrocytes. J Biol Chem (1968) 1.31
Template activity of nuclei from stimulated lymphocytes. Nature (1969) 1.31
Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg. J Immunol (1985) 1.30
Yin/Yang modulation of lysosomal enzyme release from polymorphonuclear leukocytes by cyclic nucleotides. Ann N Y Acad Sci (1975) 1.29
A specific inhibitor of complement (C5)-derived chemotactic activity in serum from patients with systemic lupus erythematosus. J Clin Invest (1978) 1.28
Biologically active products of complement and acute lung injury in patients with the sepsis syndrome. Am Rev Respir Dis (1984) 1.28