Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells.

PubWeight™: 1.78‹?› | Rank: Top 3%

🔗 View Article (PMID 460409)

Published in Nature on July 26, 1979

Authors

M T Hsu, M Coca-Prados

Articles citing this

Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs. Mol Cell Biol (1989) 5.52

Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types. PLoS One (2012) 5.28

mRNA poly(A) tail, a 3' enhancer of translational initiation. Mol Cell Biol (1990) 3.58

Cell-type specific features of circular RNA expression. PLoS Genet (2013) 2.98

Circular RNA is expressed across the eukaryotic tree of life. PLoS One (2014) 1.84

Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts. J Cell Biol (1994) 1.71

Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency. Genome Res (2013) 1.64

Step-wise formation of eukaryotic double-row polyribosomes and circular translation of polysomal mRNA. Nucleic Acids Res (2008) 1.07

Transcriptome-wide investigation of circular RNAs in rice. RNA (2015) 1.04

Circular RNA: a novel biomarker for progressive laryngeal cancer. Am J Transl Res (2016) 0.95

Is an observed non-co-linear RNA product spliced in trans, in cis or just in vitro? Nucleic Acids Res (2014) 0.92

Secondary structure model for mouse beta Maj globin mRNA derived from enzymatic digestion data, comparative sequence and computer analysis. Nucleic Acids Res (1986) 0.91

Connections between alternative transcription and alternative splicing in mammals. Genome Biol Evol (2010) 0.90

Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma. Sci Rep (2016) 0.89

Polyribosome binding of rabbit globin messenger RNA and messenger ribonucleoprotein labelled with bacteriophage-T4 RNA ligase and 5'-[32P] phosphocytidine 3'-phosphate. Nucleic Acids Res (1983) 0.87

Circular RNA Expression: Its Potential Regulation and Function. Trends Genet (2016) 0.87

The intertwining of transposable elements and non-coding RNAs. Int J Mol Sci (2013) 0.86

Circular RNAs in Eukaryotic Cells. Curr Genomics (2015) 0.83

Circular RNAs in monkey muscle: age-dependent changes. Aging (Albany NY) (2015) 0.82

NCLscan: accurate identification of non-co-linear transcripts (fusion, trans-splicing and circular RNA) with a good balance between sensitivity and precision. Nucleic Acids Res (2015) 0.82

An intriguing RNA species-perspectives of circularized RNA. Protein Cell (2015) 0.81

The circular RNA ciRS-7 (Cdr1as) acts as a risk factor of hepatic microvascular invasion in hepatocellular carcinoma. J Cancer Res Clin Oncol (2016) 0.81

Circles within circles: commentary on Ghosal et al. (2013) "Circ2Traits: a comprehensive database for circular RNA potentially associated with disease and traits". Front Genet (2015) 0.81

Circular RNAs: the Emerging Class of Non-coding RNAs and Their Potential Role in Human Neurodegenerative Diseases. Mol Neurobiol (2016) 0.80

Emerging roles and context of circular RNAs. Wiley Interdiscip Rev RNA (2016) 0.80

Identification of Circular RNAs from the Parental Genes Involved in Multiple Aspects of Cellular Metabolism in Barley. Front Plant Sci (2016) 0.79

Interplay of chromatin modifications and non-coding RNAs in the heart. Epigenetics (2013) 0.78

Circular RNAs in human cancer. Mol Cancer (2017) 0.78

Circular RNAs: Novel Regulators of Neuronal Development. Front Mol Neurosci (2016) 0.78

Expression dynamics, relationships, and transcriptional regulations of diverse transcripts in mouse spermatogenic cells. RNA Biol (2016) 0.77

Acfs: accurate circRNA identification and quantification from RNA-Seq data. Sci Rep (2016) 0.76

Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes. Sci Rep (2016) 0.76

Expression Patterns of Circular RNAs from Primary Kinase Transcripts in the Mammary Glands of Lactating Rats. J Breast Cancer (2015) 0.76

circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations. Sci Rep (2016) 0.76

circRNA_100290 plays a role in oral cancer by functioning as a sponge of the miR-29 family. Oncogene (2017) 0.76

CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis. Oncotarget (2016) 0.75

Harnessing the Power of SIRT1 and Non-coding RNAs in Vascular Disease. Curr Neurovasc Res (2016) 0.75

Disease onset and aging in the world of circular RNAs. J Transl Sci (2016) 0.75

Silencing CDR1as inhibits colorectal cancer progression through regulating microRNA-7. Onco Targets Ther (2017) 0.75

Identification of Circular RNAs in Kiwifruit and Their Species-Specific Response to Bacterial Canker Pathogen Invasion. Front Plant Sci (2017) 0.75

Genome-Wide Identification of Circular RNAs in Arabidopsis thaliana. Front Plant Sci (2017) 0.75

Articles by these authors

Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. I. Structure of F-prime factors. J Mol Biol (1972) 19.88

An electron microscope study of Sindbis virus RNA. Cold Spring Harb Symp Quant Biol (1974) 2.99

Electron microscope heteroduplex study of the heterogeneity of Mu phage and prophage DNA. Virology (1974) 2.72

Sequence arrangement of the 5' ends of simian virus 40 16S and 19S mRNAs. Proc Natl Acad Sci U S A (1977) 2.62

Transcription pattern of in vivo-labeled late simian virus 40 RNA: equimolar transcription beyond the mRNA 3' terminus. J Virol (1978) 2.47

Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1. Am J Hum Genet (1998) 2.31

Intracellular forms of simian virus 40 nucleoprotein complexes. I. Methods of isolation and characterization in CV-1 cells. J Virol (1979) 2.10

Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue specific and developmentally regulated expression. Mol Cell Biol (1986) 1.88

Transcription and accurate polyadenylation in vitro of RNA from the major late adenovirus 2 transcription unit. Cell (1982) 1.86

Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma. Gastroenterology (2000) 1.77

Structure of inserted bacteriophage Mu-1 DNA and physical mapping of bacterial genes by Mu-1 DNA insertion. Proc Natl Acad Sci U S A (1972) 1.65

Intracellular forms of simian virus 40 nucleoprotein complexes. II. Biochemical and electron microscopic analysis of simian virus 40 virion assembly. J Virol (1979) 1.62

cDNA from human ocular ciliary epithelium homologous to beta ig-h3 is preferentially expressed as an extracellular protein in the corneal epithelium. J Cell Physiol (1994) 1.47

Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro. Cancer Lett (1996) 1.40

Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin. FEBS Lett (1997) 1.40

Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli: structure of F100, F152, and F8 and mapping of the Escherichia coli chromosomal region fep-supE-gal-attlambda-uvrB. J Bacteriol (1978) 1.38

Persistent infection of human adenovirus type 5 in human monocyte cell lines. Virology (1992) 1.34

Visualization of nascent RNA transcripts and simultaneous transcription and replication in viral nucleoprotein complexes from adenovirus 2-infected HeLa cells. J Mol Biol (1981) 1.27

Frequent gain of copy number on the long arm of chromosome 3 in human cervical adenocarcinoma. Cancer Genet Cytogenet (2001) 1.16

Visualization of genetic recombination intermediates of human adenovirus type 2 DNA from infected HeLa cells. Nature (1980) 1.13

Evidence for variation of supercoil densities among simian virus 40 nucleoprotein complexes and for higher supercoil density in replicating complexes. J Virol (1984) 1.12

Isolation and characterization of the alpha 1-antitrypsin gene of mice. DNA (1986) 1.12

Mapping of inverted repeated DNA sequences within the genome of simian virus 40. Proc Natl Acad Sci U S A (1977) 1.11

A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells. Am J Physiol (1999) 1.09

Enzymatic analysis of 5-methylcytosine content in eukaryotic DNA. Study of intracellular Simian Virus 40 DNA. J Biol Chem (1980) 1.05

Identification of PKD2L, a human PKD2-related gene: tissue-specific expression and mapping to chromosome 10q25. Genomics (1998) 1.04

Similarity of A(3)-adenosine and swelling-activated Cl(-) channels in nonpigmented ciliary epithelial cells. Am J Physiol Cell Physiol (2000) 1.02

Electron microscopic evidence for the cruciform structure in intracellular SV40 DNA. Virology (1985) 1.02

DNA replication-mediated recombination of molecules of adenovirus 2 DNA. Proc Natl Acad Sci U S A (1981) 1.02

Intracellular forms of simian virus 40 nucleoprotein complexes. III. Study of histone modifications. J Virol (1980) 1.02

Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma. J Med Genet (2003) 1.02

Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases. Gene (1999) 1.00

Expression of Na,K-ATPase alpha subunit isoforms in the human ciliary body and cultured ciliary epithelial cells. J Cell Physiol (1989) 1.00

Expression of the TIGR gene in the iris, ciliary body, and trabecular meshwork of the human eye. Ophthalmic Genet (2000) 0.99

Intracellular forms of simian virus 40 nucleoprotein complexes. IV. Micrococcal nuclease digestion. J Virol (1982) 0.99

Gene expression of the neurotrophic pigment epithelium-derived factor in the human ciliary epithelium. Synthesis and secretion into the aqueous humor. Invest Ophthalmol Vis Sci (1996) 0.98

Adenosine stimulates Cl- channels of nonpigmented ciliary epithelial cells. Am J Physiol (1997) 0.98

Cellular distribution and differential gene expression of the three alpha subunit isoforms of the Na,K-ATPase in the ocular ciliary epithelium. J Biol Chem (1990) 0.98

Psoralen-cross-linking study of the organization of intracellular adenovirus nucleoprotein complexes. J Virol (1988) 0.98

Pathways signaling the regulatory volume decrease of cultured nonpigmented ciliary epithelial cells. Invest Ophthalmol Vis Sci (1994) 0.97

Genomic analysis II: isolation of high molecular weight heteroduplex DNA following differential methylase protection and Formamide-PERT hybridization. Nucleic Acids Res (1986) 0.95

Chromosomal aberrations in nasopharyngeal carcinoma analyzed by comparative genomic hybridization. Genes Chromosomes Cancer (1999) 0.95

Transformation of human ciliary epithelial cells by simian virus 40: induction of cell proliferation and retention of beta 2-adrenergic receptors. Proc Natl Acad Sci U S A (1986) 0.94

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension. QJM (2003) 0.93

Linear adenovirus DNA is organized into supercoiled domains in virus particles. Nucleic Acids Res (1989) 0.93

Mapping of the 3' terminus of the large late ad-2 transcript by electron microscopy. Virology (1980) 0.93

Whole cell patch clamping of ciliary epithelial cells during anisosmotic swelling. Am J Physiol (1992) 0.91

Growth of non-pigmented ciliary epithelial cells in serum-free hormone-supplemented media. Exp Eye Res (1986) 0.90

Isolation and characterization of cell-specific cDNA clones from a subtractive library of the ocular ciliary body of a single normal human donor: transcription and synthesis of plasma proteins. J Biochem (1995) 0.90

Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli: isolation of a new F-prime factor, F80, and its implication for the mechanism of F integration into the chromosome. J Bacteriol (1978) 0.89

Na+/H+ and CI-/HCO3-antiporters of bovine pigmented ciliary epithelial cells. Pflugers Arch (2000) 0.89

Cloning and characterization of liver-specific isoform of Chk1 gene from rat. J Biol Chem (2001) 0.88

Human ciliary epithelia in monolayer culture. Exp Eye Res (1984) 0.87

PGE(2), Ca(2+), and cAMP mediate ATP activation of Cl(-) channels in pigmented ciliary epithelial cells. Am J Physiol Cell Physiol (2001) 0.86

Functional and molecular characterization of a volume-activated chloride channel in rabbit corneal epithelial cells. J Membr Biol (2004) 0.85

Expression of multiple Na+,K(+)-ATPase genes reveals a gradient of isoforms along the nonpigmented ciliary epithelium: functional implications in aqueous humor secretion. J Cell Physiol (1991) 0.85

Involvement of topoisomerases in replication, transcription, and packaging of the linear adenovirus genome. J Virol (1990) 0.85

Regulatory volume decrease by cultured non-pigmented ciliary epithelial cells. Exp Eye Res (1992) 0.85

Volume regulation of cultured, transformed, non-pigmented epithelial cells from human ciliary body. Exp Eye Res (1989) 0.85

Calcium-dependent regulation of cation transport in cultured human nonpigmented ciliary epithelial cells. Am J Physiol (1993) 0.84

Renin-angiotensin system expression and secretory function in cultured human ciliary body non-pigmented epithelium. Br J Ophthalmol (2002) 0.84

Characterization of soluble guanylyl cyclase in transformed human non-pigmented epithelial cells. Biochem Biophys Res Commun (1993) 0.84

Molecular evidence that human ocular ciliary epithelium expresses components involved in phototransduction. Biochem Biophys Res Commun (2001) 0.83

Regulation of protein phosphorylation of the intermediate-sized filament vimentin in the ciliary epithelium of the mammalian eye. J Biol Chem (1985) 0.83

Tamoxifen and ATP synergistically activate Cl- release by cultured bovine pigmented ciliary epithelial cells. J Physiol (2000) 0.81

Spheroplast preparation facilitates PCR screening of yeast sequence. Biotechniques (1995) 0.81

Determination of twist and handedness of a 39-base pair segment of DNA in solution. Nature (1983) 0.81

Infection and inhibition of differentiation of human fetal skeletal myoblasts by adenovirus. Virology (1991) 0.81

Differential expression of the cellular retinaldehyde-binding protein in bovine ciliary epithelium. Exp Eye Res (1993) 0.81

Evidence that the alpha and alpha (+)isoforms of the catalytic subunit of (Na+, K+)-ATPase reside in distinct ciliary epithelial cells of the mammalian eye. Biochem Biophys Res Commun (1987) 0.81

Identification of a neuropeptide and neuropeptide-processing enzymes in aqueous humor confers neuroendocrine features to the human ocular ciliary epithelium. J Neurochem (1996) 0.80

Transcription pattern of in vivo-labeled late simian virus 40 RNA: evidence that 16S and 19S mRNA's are derived from distinct precursor RNA populations. J Virol (1980) 0.80

Na+/H+ exchange regulates intracellular pH in a cell clone derived from bovine pigmented ciliary epithelium. J Cell Physiol (1988) 0.80

Isolation of cDNA clones encoding the 80-kd subunit protein of the human autoantigen Ku (p70/p80) by antisera raised against ciliary processes of human eye donors. Invest Ophthalmol Vis Sci (1994) 0.80

Mammalian ciliary-body epithelial cells in culture produce transforming growth factor-beta. Graefes Arch Clin Exp Ophthalmol (1991) 0.80

Expression of pI(Cln) mRNA in cultured bovine lens epithelial cells: response to changes in cell volume. Curr Eye Res (1998) 0.80

Cloning of the bovine plasma selenium-dependent glutathione peroxidase (GP) cDNA from the ocular ciliary epithelium: expression of the plasma and cellular forms within the mammalian eye. J Biochem (1993) 0.79

Electrical membrane properties of a cell clone derived from human nonpigmented ciliary epithelium. Invest Ophthalmol Vis Sci (1989) 0.79

Functional expression of components of the natriuretic peptide system in human ocular nonpigmented ciliary epithelial cells. Biochem Biophys Res Commun (1999) 0.79

Interference of the simian virus 40 origin of replication by the cytomegalovirus immediate early gene enhancer: evidence for competition of active regulatory chromatin conformation in a single domain. Mol Cell Biol (2000) 0.79

Inhibition of Na(+)-K(+)-ATPase activates Na(+)-K(+)-2Cl- cotransporter activity in cultured ciliary epithelium. Am J Physiol (1994) 0.79

Gene expression of proteases and protease inhibitors in the human ciliary epithelium and ODM-2 cells. Exp Eye Res (1997) 0.79

Studies on regulation of the ascorbic acid transporter in a cell line derived from rabbit non-pigmented ciliary epithelium. Biochim Biophys Acta (1993) 0.79

Nucleotide sequence of a cDNA for the beta 2 subunit isoform of Na+,K(+)-ATPase from human retina. Biochim Biophys Acta (1994) 0.78

Gamma-interferon induces differential expression of HLA-DR, -DP and -DQ in human ciliary epithelial cells. Graefes Arch Clin Exp Ophthalmol (1991) 0.78

Potential contribution of epithelial Na+ channel to net secretion of aqueous humor. J Exp Zool (1997) 0.78

Hyposmotically activated chloride channels in cultured rabbit non-pigmented ciliary epithelial cells. J Physiol (1999) 0.78

Molecular characterization and differential gene induction of the neuroendocrine-specific genes neurotensin, neurotensin receptor, PC1, PC2, and 7B2 in the human ocular ciliary epithelium. J Neurochem (1997) 0.78

Inhibition of DNA replication of adenovirus type 5 and simian virus 40 by tunicamycin. Virology (1991) 0.78

Detection and characterization of Ca(2+)-activated K+ channels in transformed cells of human non-pigmented ciliary epithelium. Curr Eye Res (1991) 0.78

Separation of bovine pigmented ciliary epithelial cells by density gradient and further characterization in culture. Exp Eye Res (1985) 0.78

Molecular cloning of the human volume-sensitive chloride conductance regulatory protein, pICln, from ocular ciliary epithelium. Biochem Biophys Res Commun (1995) 0.78

Chloride dependent intracellular pH effects of external ATP in cultured human non-pigmented ciliary body epithelium. Curr Eye Res (2001) 0.78

Induction of pulmonary fibrosis in organ-cultured rat lung by cadmium chloride and transforming growth factor-beta1. Toxicology (1998) 0.77

Electron microscope analysis of partial denaturation of F factor deoxyribonucleic acid. J Bacteriol (1974) 0.77