Published in Proc Natl Acad Sci U S A on September 01, 1974
Recalibrated linkage map of Escherichia coli K-12. Bacteriol Rev (1976) 35.30
Control of rRNA transcription in Escherichia coli. Microbiol Rev (1995) 3.31
Guanosine 5'-diphosphate 3'-diphosphate (ppGpp): positive effector for histidine operon transcription and general signal for amino-acid deficiency. Proc Natl Acad Sci U S A (1975) 3.05
Stringent control of peptidoglycan biosynthesis in Escherichia coli K-12. J Bacteriol (1976) 2.83
Cluster of genes in Escherichia coli for ribosomal proteins, ribosomal RNA, and RNA polymerase subunits. Proc Natl Acad Sci U S A (1975) 2.63
New chromosomal location for structural genes of ribosomal proteins. Proc Natl Acad Sci U S A (1975) 2.11
P1 transduction mapping of the trg locus in rac+ and rac strains of Escherichia coli K-12. J Bacteriol (1982) 1.77
Cloning the spoT gene of Escherichia coli: identification of the spoT gene product. J Bacteriol (1979) 1.73
Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model. PLoS One (2009) 1.58
Effects of guanosine tetraphosphate on cell-free synthesis of Escherichia coli ribosomal RNA and other gene products. Proc Natl Acad Sci U S A (1975) 1.58
Genetics of the relB locus in Escherichia coli. J Bacteriol (1977) 1.41
Thiostrepton-resistant mutants exhibit relaxed synthesis of RNA. Proc Natl Acad Sci U S A (1978) 1.33
Streptomyces relC mutants with an altered ribosomal protein ST-L11 and genetic analysis of a Streptomyces griseus relC mutant. J Bacteriol (1990) 1.33
Effect of variation of charged and uncharged tRNA(Trp) levels on ppGpp synthesis in Escherichia coli. J Bacteriol (1989) 1.27
Evidence that glucose starvation-sensitive mutants are altered in the relB locus. J Bacteriol (1978) 1.14
Influence of amino acid starvation on guanosine 5'-diphosphate 3'-diphosphate basal-level synthesis in Escherichia coli. J Bacteriol (1980) 1.12
Regulation of Escherichia coli RelA requires oligomerization of the C-terminal domain. J Bacteriol (2001) 1.12
Physiological analysis of the stringent response elicited in an extreme thermophilic bacterium, Thermus thermophilus. J Bacteriol (2006) 1.07
Heat shock response in Lactobacillus plantarum. Appl Environ Microbiol (2004) 1.06
Altered ribosomes in antibiotic-resistant mutants of Mycobacterium smegmatis. Antimicrob Agents Chemother (1976) 1.02
The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment. Mol Microbiol (2011) 0.98
Fine-structure mapping of the rts, rplK, rplL, and rpoB genes of Escherichia coli. J Bacteriol (1977) 0.96
Escherichia coli mutant containing a large deletion from relA to argA. J Bacteriol (1979) 0.95
Involvement of the N terminus of ribosomal protein L11 in regulation of the RelA protein of Escherichia coli. J Bacteriol (2001) 0.94
Ribosome-dependent activation of stringent control. Nature (2016) 0.93
A RelA-SpoT homolog (Cr-RSH) identified in Chlamydomonas reinhardtii generates stringent factor in vivo and localizes to chloroplasts in vitro. Nucleic Acids Res (2002) 0.88
Organization and transcriptional analysis of a six-gene cluster around the rplK-rplA operon of Corynebacterium glutamicum encoding the ribosomal proteins L11 and L1. Appl Environ Microbiol (2001) 0.83
Ribosome•RelA structures reveal the mechanism of stringent response activation. Elife (2016) 0.81
Bacillus subtilis mutant temperature sensitive in the synthesis of ribonucleic acid. J Bacteriol (1976) 0.81
Catalytic and non-catalytic roles for the mono-ADP-ribosyltransferase Arr in the mycobacterial DNA damage response. PLoS One (2011) 0.80
Sub-inhibitory concentrations of bacteriostatic antibiotics induce relA-dependent and relA-independent tolerance to β-lactams. Antimicrob Agents Chemother (2017) 0.78
Isolation of rel mutants of Escherichia coli B/r. J Bacteriol (1983) 0.75
Evolution of a genome-encoded bias in amino acid biosynthetic pathways is a potential indicator of amino acid dynamics in the environment. Mol Biol Evol (2014) 0.75
Transduction of linked genetic characters of the host by bacteriophage P1. Virology (1955) 71.88
Growth Requirements of Virus-Resistant Mutants of Escherichia Coli Strain "B". Proc Natl Acad Sci U S A (1946) 31.37
Linkage map of Escherichia coli strain K-12. Bacteriol Rev (1972) 24.34
Requirement of an Escherichia coli 50 S ribosomal protein component for effective interaction of the ribosome with T and G factors and with guanosine triphosphate. J Biol Chem (1972) 14.68
A genetic locus for the regulation of ribonucleic acid synthesis. Proc Natl Acad Sci U S A (1961) 11.26
Two compounds implicated in the function of the RC gene of Escherichia coli. Nature (1969) 6.06
MSI and MSII made on ribosome in idling step of protein synthesis. Nature (1972) 3.89
Isolation of "relaxed" mutants of Escherichia coli. J Bacteriol (1968) 3.61
Synthesis of guanosine tetra- and pentaphosphate requires the presence of a codon-specific, uncharged transfer ribonucleic acid in the acceptor site of ribosomes. Proc Natl Acad Sci U S A (1973) 3.52
Accumulation and turnover of guanosine tetraphosphate in Escherichia coli. J Mol Biol (1972) 2.56
Artificial elimination of the F factor in Bact. coli K-12. Nature (1956) 2.40
Codon specific, tRNA dependent in vitro synthesis of ppGpp and pppGpp. Nat New Biol (1973) 2.36
Ribosomal proteins. Protein compositions of biosynthetic precursors and artifical subparticles from ribosomal subunits in Escherichia coli K 12. Eur J Biochem (1971) 1.77
Mutations and genetics concerned with the ribosome. Cold Spring Harb Symp Quant Biol (1966) 1.68
Polarity in relaxed strains of Salmonella typhimurium. J Mol Biol (1968) 1.47
The structural gene for the ribosomal protein S18 in Escherichia coli. I. Genetic studies on a mutant having an alteration in the protein S18. J Mol Biol (1973) 1.44
Thermolability of the stringent factor in rel mutants of Escherichia coli. J Mol Biol (1973) 1.36
Diazomethane as the active agent in nitrosoguanidine mutagenesis and lethality. Mol Gen Genet (1968) 1.24
Nonribosomal synthesis of guanosine 5',3'-polyphosphates by the ribosomal wash of stringent Escherichia coli. Proc Natl Acad Sci U S A (1973) 1.19
Localization of the stringent protein of Escherichia coli on the 50S ribosomal subunit. Proc Natl Acad Sci U S A (1974) 1.14
Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1989) 12.54
The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat. Cell (1985) 11.28
The trans-activator gene of the human T cell lymphotropic virus type III is required for replication. Cell (1986) 10.76
Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity. Nature (1986) 10.62
Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release. Proc Natl Acad Sci U S A (1991) 10.05
Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells. Science (1984) 9.14
Mutation of a mutL homolog in hereditary colon cancer. Science (1994) 9.04
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III. Science (1985) 8.53
Rous sarcoma virus genome is terminally redundant: the 5' sequence. Proc Natl Acad Sci U S A (1977) 7.09
The Bactericidal Effect of Sulfanilamide upon Beta Hemolytic Streptococci in Vitro. J Bacteriol (1938) 6.73
Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat. Science (1985) 6.51
Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature (1994) 6.21
Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes. J Virol (1992) 5.85
Functional role of human immunodeficiency virus type 1 vpu. Proc Natl Acad Sci U S A (1989) 5.72
The nucleotide sequence of tufB and four nearby tRNA structural genes of Escherichia coli. Gene (1980) 5.66
Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex. J Virol (1991) 5.49
Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus. Proc Natl Acad Sci U S A (1988) 5.47
Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III. Nature (1986) 5.24
New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites. Biochemistry (1986) 5.12
Determination of the leukaemogenicity of a murine retrovirus by sequences within the long terminal repeat. Nature (1984) 4.90
Ordered transcription of RNA tumor virus genomes. J Mol Biol (1976) 4.78
Integration of human immunodeficiency virus type 1 DNA in vitro. Proc Natl Acad Sci U S A (1990) 4.75
Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity. J Virol (1986) 4.48
Identification of HIV-1 vpr product and function. J Acquir Immune Defic Syndr (1990) 4.35
Human immunodeficiency virus vpr product is a virion-associated regulatory protein. J Virol (1990) 4.35
Tissue-specific transcription preference as a determinant of cell tropism and leukaemogenic potential of murine retroviruses. Nature (1984) 4.30
Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein. J Virol (1994) 4.28
Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein. J Virol (1993) 4.22
Identification of a protein encoded by the vpu gene of HIV-1. Nature (1988) 4.05
MSI and MSII made on ribosome in idling step of protein synthesis. Nature (1972) 3.89
Herpes simplex virus type-1 can reactivate transcription of latent human immunodeficiency virus. Nature (1987) 3.77
Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2. EMBO J (1992) 3.65
UV-induced mutation hotspots occur at DNA damage hotspots. Nature (1982) 3.63
Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses. Proc Natl Acad Sci U S A (1993) 3.63
Isolation of "relaxed" mutants of Escherichia coli. J Bacteriol (1968) 3.61
Structural and functional characterization of human immunodeficiency virus tat protein. J Virol (1989) 3.57
Synthesis of guanosine tetra- and pentaphosphate requires the presence of a codon-specific, uncharged transfer ribonucleic acid in the acceptor site of ribosomes. Proc Natl Acad Sci U S A (1973) 3.52
Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin. Proc Natl Acad Sci U S A (1978) 3.43
Antigens encoded by the 3'-terminal region of human T-cell leukemia virus: evidence for a functional gene. Science (1984) 3.20
Drug reactions and errors in administration on a medical ward. Can Med Assoc J (1967) 3.00
Low-molecular-weight RNAs of Moloney murine leukemia virus: identification of the primer for RNA-directed DNA synthesis. J Virol (1977) 2.99
Specific binding of tryptophan transfer RNA to avian myeloblastosis virus RNA-dependent DNA polymerase (reverse transcriptase). Proc Natl Acad Sci U S A (1975) 2.97
Cis-acting sequences responsive to the rev gene product of the human immunodeficiency virus. J Acquir Immune Defic Syndr (1988) 2.97
Computer keyboards and faucet handles as reservoirs of nosocomial pathogens in the intensive care unit. Am J Infect Control (2000) 2.95
Distribution of UV light-induced damage in a defined sequence of human DNA: detection of alkaline-sensitive lesions at pyrimidine nucleoside-cytidine sequences. Proc Natl Acad Sci U S A (1981) 2.92
Plasmid vehicles for direct cloning of Escherichia coli promoters. J Bacteriol (1979) 2.87
Mutations in a yeast intron demonstrate the importance of specific conserved nucleotides for the two stages of nuclear mRNA splicing. Cell (1986) 2.73
HIV/HTLV gene nomenclature. Nature (1988) 2.72
Cleavage of pyrimidine dimers in specific DNA sequences by a pyrimidine dimer DNA-glycosylase of M. luteus. Nature (1980) 2.72
Structure of the genome of Moloney murine leukemia virus: a terminally redundant sequence. Cell (1978) 2.68
Activation of human immunodeficiency virus by herpesvirus infection: identification of a region within the long terminal repeat that responds to a trans-acting factor encoded by herpes simplex virus 1. Proc Natl Acad Sci U S A (1987) 2.66
Subcellular localization of the human immunodeficiency virus trans-acting art gene product. J Virol (1988) 2.64
Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector. Proc Natl Acad Sci U S A (1989) 2.64
Genetic interaction between transcription elongation factor TFIIS and RNA polymerase II. Mol Cell Biol (1992) 2.59
Accumulation and turnover of guanosine tetraphosphate in Escherichia coli. J Mol Biol (1972) 2.56
Biosynthetic regulation of individual proteins in relA+ and relA strains of Escherichia coli during amino acid starvation. Mol Gen Genet (1976) 2.51
Construction of recombinant murine retroviruses that express the human T-cell leukemia virus type II and human T-cell lymphotropic virus type III trans activator genes. J Virol (1986) 2.50
Sites and structure of gamma radiation-induced DNA strand breaks. J Biol Chem (1982) 2.47
The nucleotide sequence and characterization of the relA gene of Escherichia coli. J Biol Chem (1988) 2.45
gamma Ray induced deoxyribonucleic acid strand breaks. 3' Glycolate termini. J Biol Chem (1983) 2.41
A micromethod for detailed characterization of high molecular weight RNA. Methods Enzymol (1980) 2.36
Cellular content of ribonucleic acid and protein in Saccharomyces cerevisiae as a function of exponential growth rate: calculation of the apparent peptide chain elongation rate. J Bacteriol (1975) 2.32
Structure of 3' terminal region of type II human T lymphotropic virus: evidence for new coding region. Science (1984) 2.32
Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences. J Virol (1985) 2.29
Genetic analysis of the human immunodeficiency virus type 1 integrase protein. J Virol (1994) 2.26
Location of cis-acting regulatory sequences in the human T-cell leukemia virus type I long terminal repeat. Proc Natl Acad Sci U S A (1985) 2.25
Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures. Proc Natl Acad Sci U S A (1991) 2.25
Subcellular localization of the product of the long open reading frame of human T-cell leukemia virus type I. Science (1985) 2.25
Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine. Proc Natl Acad Sci U S A (1987) 2.25
Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture. J Virol (1992) 2.21
Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles. J Virol (1994) 2.20
Stuttering: high-level mistranslation in animal and bacterial cells. Proc Natl Acad Sci U S A (1978) 2.15
Circularization of human immunodeficiency virus type 1 DNA in vitro. J Virol (1991) 2.14
Characterization of promoter-cloning plasmids: analysis of operon structure in the rif region of Escherichia coli and isolation of an enhanced internal promoter mutant. J Bacteriol (1980) 2.13
New chromosomal location for structural genes of ribosomal proteins. Proc Natl Acad Sci U S A (1975) 2.11
Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody. Proc Natl Acad Sci U S A (1993) 2.10
Envelope glycoprotein and CD4 independence of vpu-facilitated human immunodeficiency virus type 1 capsid export. J Virol (1992) 2.05
Nucleotide sequence of the tcml gene (ribosomal protein L3) of Saccharomyces cerevisiae. J Bacteriol (1983) 2.05
Genomic changes associated with antigenic variation of visna virus durig persistent infection. Proc Natl Acad Sci U S A (1980) 2.04
Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression. Science (1986) 2.03
Polymorphism of the 3' open reading frame of the virus associated with the acquired immune deficiency syndrome, human T-lymphotropic virus type III. Nucleic Acids Res (1985) 2.01
A tripartite HIV-1 tat-env-rev fusion protein. EMBO J (1990) 2.01
Use of exonuclease III to determine the site of stable lesions in defined sequences of DNA: the cyclobutane pyrimidine dimer and cis and trans dichlorodiammine platinum II examples. Nucleic Acids Res (1981) 1.97
Novel leukaemogenic retroviruses isolated from cell line derived from spontaneous AKR tumour. Nature (1981) 1.97
deaD, a new Escherichia coli gene encoding a presumed ATP-dependent RNA helicase, can suppress a mutation in rpsB, the gene encoding ribosomal protein S2. J Bacteriol (1991) 1.96
Construction and use of a replication-competent human immunodeficiency virus (HIV-1) that expresses the chloramphenicol acetyltransferase enzyme. Proc Natl Acad Sci U S A (1989) 1.96
PRP4 (RNA4) from Saccharomyces cerevisiae: its gene product is associated with the U4/U6 small nuclear ribonucleoprotein particle. Mol Cell Biol (1989) 1.95
Terminal redundancy and the origin of replication of Rous sarcoma virus RNA. Proc Natl Acad Sci U S A (1977) 1.94
Comparison of the cleavage of pyrimidine dimers by the bacteriophage T4 and Micrococcus luteus UV-specific endonucleases. J Biol Chem (1980) 1.92
Effects of long terminal repeat mutations on human immunodeficiency virus type 1 replication. J Virol (1989) 1.91
Biochemical evidence that "new" influenza virus strains in nature may arise by recombination (reassortment). Proc Natl Acad Sci U S A (1978) 1.86
Transepithelial transport of HIV-1 by intestinal M cells: a mechanism for transmission of AIDS. J Acquir Immune Defic Syndr (1991) 1.85
Expression of reverse transcriptase activity of human T-lymphotropic virus type III (HTLV-III/LAV) in Escherichia coli. J Virol (1986) 1.84
Protein production: feeding the crystallographers and NMR spectroscopists. Nat Struct Biol (2000) 1.84
Antigen-antibody interaction. Synthetic peptides define linear antigenic determinants recognized by monoclonal antibodies directed to the cytoplasmic carboxyl terminus of rhodopsin. J Biol Chem (1988) 1.82
Inhibitors of ribonucleic acid synthesis in Saccharomyces cerevisiae: decay rate of messenger ribonucleic acid. J Bacteriol (1973) 1.81
Alkaline lability of fluorescent photoproducts produced in ultraviolet light-irradiated DNA. J Biol Chem (1982) 1.79
Interaction of alleles of the relA, relC and spoT genes in Escherichia coli: analysis of the interconversion of GTP, ppGpp and pppGpp. Mol Gen Genet (1977) 1.79