Published in Trans R Soc Trop Med Hyg on January 01, 1972
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response. J Exp Med (2003) 2.71
IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis. Proc Natl Acad Sci U S A (2003) 1.80
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J Immunol (2001) 4.59
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J Clin Invest (1999) 4.22
Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J Immunol (1993) 3.34
Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunol Rev (1989) 3.21
IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis. J Immunol (2000) 3.03
Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med (1994) 2.99
Conditions affecting the accuracy of potassium hydroxide digestion techniques for counting Schistosoma mansoni eggs in tissues. Bull World Health Organ (1968) 2.58
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection. Nature (1995) 2.52
Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni. Proc Natl Acad Sci U S A (1990) 2.37
Effects of interleukin 12 on immune responses and host protection in mice infected with intestinal nematode parasites. J Exp Med (1994) 2.22
A quantitative post-mortem study of Schistosomiasis mansoni in man. Am J Trop Med Hyg (1968) 2.22
IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis. J Immunol (1997) 2.09
Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: cytokine requirements for the induction and maintenance of intestinal inflammation. Infect Immun (2001) 1.99
IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs. J Immunol (1999) 1.91
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis. Hepatology (2001) 1.90
Ablation of eosinophil and IgE responses with anti-IL-5 or anti-IL-4 antibodies fails to affect immunity against Schistosoma mansoni in the mouse. J Immunol (1990) 1.88
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile. J Immunol (1999) 1.78
Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. J Exp Med (1996) 1.68
NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease. Am J Pathol (2000) 1.67
Mutation of Tec family kinases alters T helper cell differentiation. Nat Immunol (2001) 1.63
Pathological lesions associated with Schistosoma mansoni infection in man. Trans R Soc Trop Med Hyg (1967) 1.61
Pathogenesis of post-thymectomy autoimmune gastritis. Identification of anti-H/K adenosine triphosphatase-reactive T cells. J Immunol (1996) 1.60
CD4+ T cell-mediated granulomatous pathology in schistosomiasis is downregulated by a B cell-dependent mechanism requiring Fc receptor signaling. J Exp Med (1998) 1.56
Regulation of hepatic fibrosis and extracellular matrix genes by the th response: new insight into the role of tissue inhibitors of matrix metalloproteinases. J Immunol (2001) 1.55
Pathogenesis of post-thymectomy autoimmunity. Role of syngeneic MLR-reactive T cells. J Immunol (1995) 1.55
IL-10 regulates liver pathology in acute murine Schistosomiasis mansoni but is not required for immune down-modulation of chronic disease. J Immunol (1998) 1.54
Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni. J Immunol (1999) 1.53
The acquisition and loss of antigen-specific cellular immune responsiveness in acute and chronic schistosomiasis in man. Clin Exp Immunol (1978) 1.40
Schistosoma mansoni and S. haematobium infections in Egypt. II. Quantitative parasitological findings at necropsy. Am J Trop Med Hyg (1977) 1.37
Cytokine regulation of granuloma formation in schistosomiasis. Curr Opin Immunol (1995) 1.36
IFN inhibits inflammatory responses and protective immunity in mice infected with the nematode parasite, Nippostrongylus brasiliensis. J Immunol (1993) 1.36
Counting of Schistosoma mansoni eggs in feces. Comparison of a filtration technique and a dilution technique. J Parasitol (1968) 1.36
Immunopathology of schistosomiasis mansoni in mice and men. Immunol Today (2000) 1.34
Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions. FASEB J (2001) 1.30
Schistosome infections in humans: perspectives and recent findings. NIH conference. Ann Intern Med (1982) 1.25
Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms. J Immunol (1999) 1.24
Analysis of granuloma formation in double cytokine-deficient mice reveals a central role for IL-10 in polarizing both T helper cell 1- and T helper cell 2-type cytokine responses in vivo. J Immunol (1997) 1.23
Quantitative comparison of the intensity of Schistosoma mansoni infections in man and experimental animals. Trans R Soc Trop Med Hyg (1969) 1.22
IL-12 exacerbates rather than suppresses T helper 2-dependent pathology in the absence of endogenous IFN-gamma. J Immunol (1995) 1.19
IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia. J Immunol (1995) 1.18
Variation of hepatic fibrosis and granuloma size among mouse strains infected with Schistosoma mansoni. Am J Trop Med Hyg (1987) 1.18
Fibroblast stimulation in schistosomiasis. I. Stimulation in vitro of fibroblasts by soluble products of egg granulomas. J Infect Dis (1981) 1.16
Immunopathology of Schistosoma japonicum and S. mansoni infection in B cell depleted mice. Parasite Immunol (1985) 1.12
Comparison of geographical strains of Schistosoma mansoni in the mouse. Bull World Health Organ (1972) 1.11
Diagnosis of pathologically confirmed Symmers' periportal fibrosis by ultrasonography: a prospective blinded study. Am J Trop Med Hyg (1988) 1.11
IL-12 enhances vaccine-induced immunity to schistosomes by augmenting both humoral and cell-mediated immune responses against the parasite. J Immunol (1996) 1.11
Testing time-, ignorance-, and danger-based models of tolerance. J Immunol (2001) 1.08
IFN-gamma, IL-12, and TNF-alpha are required to maintain reduced liver pathology in mice vaccinated with Schistosoma mansoni eggs and IL-12. J Immunol (1998) 1.08
Experimental infection with Schistosoma haematobium in chimpanzees. Am J Trop Med Hyg (1970) 1.07
Isolation of a polysaccharide antigen from Schistosoma mansoni eggs. J Immunol (1979) 1.06
A histopathological analysis of the course of myocarditis in C3H/He mice infected with Trypanosoma cruzi clone Sylvio-X10/4. Trans R Soc Trop Med Hyg (1986) 1.06
Dynamic analysis of splenic Th1 and Th2 lymphocyte functions in mice infected with Schistosoma japonicum. Infect Immun (1991) 1.05
Schistosoma mansoni infection in rhesus monkeys: changes in egg production and egg distribution in prolonged infections in intact and splenectomized monkeys. Ann Trop Med Parasitol (1969) 1.05
Schistosoma mansoni and S. haematobium infections in Egypt. III. Extrahepatic pathology. Am J Trop Med Hyg (1978) 1.03
Relative resistance of the eggs of human schistosomes to digestion in potassium hydroxide. Bull World Health Organ (1970) 1.03
Immunopathology of Schistosoma japonicum infection in athymic mice. Parasite Immunol (1985) 1.02
Experimental infection with Schistosoma japonicum in chimpanzees. Am J Trop Med Hyg (1971) 0.98
Immunoglobulin and complement receptors on human eosinophils and their role in cellular adherence to schistosomules. Am J Trop Med Hyg (1977) 0.97
Proliferative epithelial lesions of the urinary bladder of nonhuman primates infected with Schistosoma haematobium. J Natl Cancer Inst (1972) 0.96
The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs. Infect Immun (1999) 0.96
CpG oligonucleotides can prophylactically immunize against Th2-mediated schistosome egg-induced pathology by an IL-12-independent mechanism. J Immunol (2000) 0.95
Streptozotocin-induced diabetes mellitus and the host-parasite relation in murine schistosomiasis mansoni. J Infect Dis (1975) 0.94
Schistosomiasis and neoplasia. J Natl Cancer Inst (1978) 0.94
Studies on egg excretion and tissue egg burden in urinary schistosomiasis. Am J Trop Med Hyg (1974) 0.93
Interleukin 5 (IL-5) is not required for expression of a Th2 response or host resistance mechanisms during murine schistosomiasis mansoni but does play a role in development of IL-4-producing non-T, non-B cells. Infect Immun (1999) 0.93
Schistosomiasis haematobia in African, hamadryas, and gelada baboons. Am J Trop Med Hyg (1974) 0.93
Fc epsilonRI-deficient mice infected with Schistosoma mansoni mount normal Th2-type responses while displaying enhanced liver pathology. J Immunol (1997) 0.93
Schistosomiasis mansoni in the chimpanzee. The natural history of chronic infections after single and multiple exposures. Am J Trop Med Hyg (1970) 0.93
Calcification of the bladder and papillary tumours of the bladder and ureters in gibbons (Hylobates lar) infected with Schistosoma haematobium (Iran). Trans R Soc Trop Med Hyg (1975) 0.92
Antibody response to a polysaccharide antigen present in the schistosome gut. II. Modulation of antibody response. Am J Trop Med Hyg (1978) 0.92
Differences in hepatic fibrosis and granuloma size in several strains of mice infected with Schistosoma japonicum. Am J Trop Med Hyg (1984) 0.91
Rate of destruction of Schistosoma mansoni eggs and adult worms in the tissues of rhesus monkeys. Am J Trop Med Hyg (1971) 0.90
Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responses and chemokines in vivo. Infect Immun (2001) 0.89
Rate of destruction of Schistosoma mansoni eggs in the tissues of mice. Am J Trop Med Hyg (1971) 0.89
Analysis and antigenic activity of a carbohydrate fraction derived from adult Schistosoma mansoni. J Immunol (1981) 0.88
Schistosoma mansoni infection in rhesus monkeys: comparison of the course of heavy and light infections. Bull World Health Organ (1972) 0.88
Influence of parasite strain on chemotherapy of murine infections with Schistosoma mansoni. Bull World Health Organ (1971) 0.87
Cytokine regulation of schistosome-induced granuloma and fibrosis. Kidney Int (1997) 0.87
Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling to downregulate T-helper 2 responses. Immunology (1999) 0.86
Suppressive effect of interleukin-4 neutralization differs for granulomas around Schistosoma mansoni eggs injected into mice compared with those around eggs laid in infected mice. Infect Immun (1995) 0.85
Relationship between acquired resistance, portal hypertension, and lung granulomas in ten strains of mice infected with Schistosoma mansoni. Am J Trop Med Hyg (1981) 0.85
Serological differences between acute and chronic schistosomiasis mansoni detected by enzyme-linked immunosorbent assay (ELISA). Am J Trop Med Hyg (1979) 0.84
Schistosoma mansoni: mice infected with different worm strains. Exp Parasitol (1979) 0.84
The intensity of experimental schistosome infections modulates hepatic pathology. Am J Trop Med Hyg (1986) 0.84
Schistosoma haematobium: the pathology of experimental infection. Exp Parasitol (1985) 0.83
Alterations of the intrahepatic vasculature in hepatosplenic schistosomiasis mansoni. Am J Trop Med Hyg (1971) 0.83
Schistosoma mansoni and S. haematobium infections in Egypt. I. Evaluation of techniques for recovery of worms and eggs at necropsy. Am J Trop Med Hyg (1977) 0.82
Characterization of the murine model of schistosomal hepatic periportal fibrosis ('pipestem' fibrosis). Int J Exp Pathol (1993) 0.82
Hepatic fibrosis in rabbits infected with Japanese and Philippine strains of Schistosoma japonicum. Am J Trop Med Hyg (1980) 0.82
Schistosomiasis and colon cancer. Lancet (1981) 0.82
Hepatic fibrosis in Schistosoma haematobium-infected mice. Trans R Soc Trop Med Hyg (1983) 0.81
Schistosoma mansoni in baboons. III. The course and characteristics of infection, with additional observations on immunity. Am J Trop Med Hyg (1976) 0.81
Schistosoma japonicum: the pathology of experimental infection. Exp Parasitol (1985) 0.80
The Hoeppli phenomenon in schistosomiasis. Comparative pathology and immunopathology. Am J Trop Med Hyg (1966) 0.80
Schistosoma japonicum infection in monkeys and baboons: parasitological and pathological findings. Am J Trop Med Hyg (1974) 0.79
Cell-mediated and humoral immune responses in capuchin monkeys infected with Schistosoma japonicum or Schistosoma mansoni. Am J Trop Med Hyg (1983) 0.79
Animal model of human disease: carcinoma of the urinary bladder in Schistosoma haematobium infection. Am J Pathol (1976) 0.79
Schistosoma mansoni: fractionation of polysaccharide egg antigens by lectin affinity chromatography. Immunology (1982) 0.79
Reversal of advanced liver fibrosis in rabbits with Schistosomiasis japonica. Am J Trop Med Hyg (1994) 0.79