Published in J Cell Biol on October 01, 1990
Coronin, an actin binding protein of Dictyostelium discoideum localized to cell surface projections, has sequence similarities to G protein beta subunits. EMBO J (1991) 2.20
Dictyostelium mutants lacking the cytoskeletal protein coronin are defective in cytokinesis and cell motility. J Cell Biol (1993) 2.12
Unexpected combinations of null mutations in genes encoding the actin cytoskeleton are lethal in yeast. Mol Biol Cell (1993) 1.66
A talin homologue of Dictyostelium rapidly assembles at the leading edge of cells in response to chemoattractant. J Cell Biol (1995) 1.37
Integrated maps of the chromosomes in Dictyostelium discoideum. Genetics (1995) 1.31
Cell-substrate interactions and locomotion of Dictyostelium wild-type and mutants defective in three cytoskeletal proteins: a study using quantitative reflection interference contrast microscopy. Biophys J (1995) 1.28
Targeted disruption of the ABP-120 gene leads to cells with altered motility. J Cell Biol (1992) 1.24
The Ca(2+)-binding domains in non-muscle type alpha-actinin: biochemical and genetic analysis. J Cell Biol (1993) 1.22
Interaction of a Dictyostelium member of the plastin/fimbrin family with actin filaments and actin-myosin complexes. Mol Biol Cell (1997) 1.19
Establishment of a system for conditional gene expression using an inducible tRNA suppressor gene. Mol Cell Biol (1992) 1.11
Mechanical perturbation elicits a phenotypic difference between Dictyostelium wild-type cells and cytoskeletal mutants. Biophys J (1996) 1.08
Dictyostelium discoideum mutants with conditional defects in phagocytosis. J Cell Biol (1994) 1.04
Genetic deletion of ABP-120 alters the three-dimensional organization of actin filaments in Dictyostelium pseudopods. J Cell Biol (1995) 1.04
Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium. J Cell Biol (1994) 1.02
Dictyostelium discoideum cells lacking the 34,000-dalton actin-binding protein can grow, locomote, and develop, but exhibit defects in regulation of cell structure and movement: a case of partial redundancy. J Cell Biol (1996) 0.95
Regulation of the actin cytoskeleton by an interaction of IQGAP related protein GAPA with filamin and cortexillin I. PLoS One (2010) 0.94
Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants. Mol Biol Cell (1996) 0.93
Actin binding domains direct actin-binding proteins to different cytoskeletal locations. BMC Cell Biol (2008) 0.93
Villidin, a novel WD-repeat and villin-related protein from Dictyostelium, is associated with membranes and the cytoskeleton. Mol Biol Cell (2003) 0.83
Heteromeric p97/p97R155C complexes induce dominant negative changes in wild-type and autophagy 9-deficient Dictyostelium strains. PLoS One (2012) 0.82
A cytohesin homolog in Dictyostelium amoebae. PLoS One (2010) 0.81
A 27,000-D core of the Dictyostelium 34,000-D protein retains Ca(2+)-regulated actin cross-linking but lacks bundling activity. J Cell Biol (1993) 0.80
Filamin repeat segments required for photosensory signalling in Dictyostelium discoideum. BMC Cell Biol (2007) 0.80
The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions. Open Biol (2015) 0.78
Identification of the protein kinases Pyk3 and Phg2 as regulators of the STATc-mediated response to hyperosmolarity. PLoS One (2014) 0.78
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene (1985) 213.67
The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem (1971) 35.39
Actin and actin-binding proteins. A critical evaluation of mechanisms and functions. Annu Rev Biochem (1986) 9.17
Growth of myxameobae of the cellular slime mould Dictyostelium discoideum in axenic culture. Biochem J (1970) 8.98
A technique for ultracryotomy of cell suspensions and tissues. J Cell Biol (1973) 8.64
Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. Science (1987) 8.51
Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum. Science (1987) 6.13
Nonmuscle actin-binding proteins. Annu Rev Cell Biol (1985) 5.46
Membrane and cytoplasmic changes in B lymphocytes induced by ligand-surface immunoglobulin interaction. Adv Immunol (1976) 4.18
Viscometric analysis of the gelation of Acanthamoeba extracts and purification of two gelation factors. J Cell Biol (1980) 3.53
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. Nature (1986) 3.50
Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain. Dev Biol (1988) 3.48
Cell communication by periodic cyclic-AMP pulses. Philos Trans R Soc Lond B Biol Sci (1975) 2.34
Chemotactic reorientation of granulocytes stimulated with micropipettes containing fMet-Leu-Phe. J Cell Sci (1981) 2.12
A genetic study of aggregation in the cellular slime mould Dictyostelium discoideum using complementation analysis. Genetics (1976) 2.09
Microinjection of gelsolin into living cells. J Cell Biol (1987) 2.06
The sequence of chick alpha-actinin reveals homologies to spectrin and calmodulin. J Biol Chem (1987) 1.95
Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains. J Biol Chem (1988) 1.91
Visualization of the same PtK2 cytoskeletons by both immunofluorescence and low power electron microscopy. Exp Cell Res (1978) 1.88
Alternative developmental pathways determined by environmental conditions in the cellular slime mold Dictyostelium discoideum. J Bacteriol (1969) 1.87
Calcium-sensitive non-muscle alpha-actinin contains EF-hand structures and highly conserved regions. FEBS Lett (1987) 1.86
Presence of nuclear associated plasmids in the lower eukaryote Dictyostelium discoideum. J Mol Biol (1985) 1.81
Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein. EMBO J (1987) 1.79
Quantitative analysis of cell motility and chemotaxis in Dictyostelium discoideum by using an image processing system and a novel chemotaxis chamber providing stationary chemical gradients. J Cell Biol (1989) 1.78
Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis. Cell (1982) 1.75
Electron microscopic mapping of monoclonal antibodies on the tail region of Dictyostelium myosin. EMBO J (1982) 1.75
Carbohydrate and other epitopes of the contact site A glycoprotein of Dictyostelium discoideum as characterized by monoclonal antibodies. Cell Differ (1985) 1.71
New actin-binding proteins from Dictyostelium discoideum. EMBO J (1984) 1.68
Erythrocyte membrane tropomyosin. Purification and properties. J Biol Chem (1984) 1.59
Selection of Dictyostelium mutants defective in cytoskeletal proteins: use of an antibody that binds to the ends of alpha-actinin rods. EMBO J (1986) 1.56
Disruption of microfilament organization after injection of F-actin capping proteins into living tissue culture cells. Nature (1983) 1.49
Properties of the 120,000- and 95,000-dalton actin-binding proteins from Dictyostelium discoideum and their possible functions in assembling the cytoplasmic matrix. J Cell Biol (1984) 1.46
Calmodulin localization during capping and receptor-mediated endocytosis. Nature (1981) 1.46
Actin polymerization and pseudopod extension during amoeboid chemotaxis. Cell Motil Cytoskeleton (1988) 1.45
An improved mounting medium for immunofluorescence microscopy. Am J Clin Pathol (1978) 1.45
A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis. J Cell Biol (1989) 1.40
Developmentally regulated transcription of Dictyostelium discoideum plasmid Ddp1. EMBO J (1985) 1.40
The Dictyostelium gelation factor shares a putative actin binding site with alpha-actinins and dystrophin and also has a rod domain containing six 100-residue motifs that appear to have a cross-beta conformation. J Cell Biol (1989) 1.37
Changes in actin associated with the cytoskeleton following chemotactic stimulation of dictyostelium discoideum. Biochem Biophys Res Commun (1983) 1.35
[1,4-Diazobicyclo-(2,2,2)-octane (DABCO) retards the fading of immunofluorescence preparations]. Mikroskopie (1983) 1.18
Ligand-induced changes in the location of actin, myosin, 95K (alpha-actinin), and 120K protein in amebae of Dictyostelium discoideum. J Cell Biol (1985) 1.17
Changes in the association of actin-binding proteins with the actin cytoskeleton during chemotactic stimulation of Dictyostelium discoideum. Cell Motil Cytoskeleton (1989) 1.16
A Dictyostelium mutant with severe defects in alpha-actinin: its characterization using cDNA probes and monoclonal antibodies. J Cell Sci (1988) 1.15
Translocations in Dictyostelium discoideum. Genetics (1985) 1.15
Selection of chemotaxis mutants of Dictyostelium discoideum. J Cell Biol (1987) 1.11
Signal transduction, chemotaxis, and cell aggregation in Dictyostelium discoideum cells without myosin heavy chain. Dev Biol (1988) 1.04
Characterization of Dominant Resistance to Cobalt Chloride in DICTYOSTELIUM DISCOIDEUM and Its Use in Parasexual Genetic Analysis. Genetics (1978) 0.98
Electron microscopic localization of myosin II and ABP-120 in the cortical actin matrix of Dictyostelium amoebae using IgG-gold conjugates. Dev Genet (1988) 0.98
Controlled growth of colloidal gold particles and implications for labelling efficiency. Histochemistry (1986) 0.97
Cytoskeletons from a mutant of Dictyostelium discoideum with flattened cells. J Cell Sci (1986) 0.94
Fine structure of gels prepared from an actin-binding protein and actin: comparison to cytoplasmic extracts and cortical cytoplasm in amoeboid cells of cortical cytoplasm in amoeboid cells of Dictyostelium discoideum. J Cell Biochem (1986) 0.93
Vectors for expression of truncated coding sequences in Escherichia coli. Plasmid (1988) 0.91
Cell motility. Networks from mutants. Nature (1989) 0.91
Genetic approaches to cytoskeleton function and the control of cell motility. Curr Opin Cell Biol (1989) 0.91
Actin-binding proteins are conserved from slime molds to man. Dev Genet (1988) 0.88
Stress fiber dynamics as probed by antibodies against myosin. Eur J Cell Biol (1988) 0.87
Isolation and behavioral analysis of mutants defective in cytoskeletal proteins. Cell Motil Cytoskeleton (1989) 0.85
A single base exchange in an intron of the Dictyostelium discoideum alpha-actinin gene inhibits correct splicing of the RNA but allows transport to the cytoplasm and translation. J Biol Chem (1990) 0.83
Improved negative staining of microfilament arrangements in detergent-extracted Physarum amoeboflagellates. Exp Cell Res (1985) 0.81
Biological roles of actin-binding proteins in Dictyostelium discoideum examined using genetic techniques. Cell Motil Cytoskeleton (1989) 0.80
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium". Pflugers Arch (1982) 6.81
Filamins as integrators of cell mechanics and signalling. Nat Rev Mol Cell Biol (2001) 5.99
Temporal comparisons in bacterial chemotaxis. Proc Natl Acad Sci U S A (1986) 5.67
Impulse responses in bacterial chemotaxis. Cell (1982) 4.95
Adaptation kinetics in bacterial chemotaxis. J Bacteriol (1983) 4.31
Superresolution three-dimensional images of fluorescence in cells with minimal light exposure. Science (1995) 4.16
Signal processing times in bacterial chemotaxis. Nature (1982) 3.81
Polarity of actin at the leading edge of cultured cells. Nature (1978) 3.40
EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells. J Cell Sci (1998) 3.12
Action potentials and net membrane currents of isolated smooth muscle cells (urinary bladder of the guinea-pig). Pflugers Arch (1985) 3.12
An actin-binding protein from Acanthamoeba regulates actin filament polymerization and interactions. Nature (1980) 3.04
A critical step in metastasis: in vivo analysis of intravasation at the primary tumor. Cancer Res (2000) 3.03
Discrete interactions in cell adhesion measured by single-molecule force spectroscopy. Nat Cell Biol (2000) 2.94
Intracellular oscillations and release of cyclic AMP from Dictyostelium cells. Biochem Biophys Res Commun (1975) 2.84
Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation. Proc Natl Acad Sci U S A (1981) 2.84
Dynamics of antigenic membrane sites relating to cell aggregation in Dictyostelium discoideum. J Cell Biol (1973) 2.73
Cardiac Purkinje fibers: cesium as a tool to block inward rectifying potassium currents. Pflugers Arch (1976) 2.69
Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude. Pflugers Arch (1982) 2.69
Chemotactic signaling in filamentous cells of Escherichia coli. J Bacteriol (1985) 2.69
A specific glycoprotein as the target site of adhesion blocking Fab in aggregating Dictyostelium cells. Nature (1978) 2.64
Microfilament dynamics during cell movement and chemotaxis monitored using a GFP-actin fusion protein. Curr Biol (1997) 2.57
Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion. J Cell Biol (2000) 2.56
Coronin involved in phagocytosis: dynamics of particle-induced relocalization visualized by a green fluorescent protein Tag. Cell (1995) 2.42
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts. J Cell Biol (1995) 2.39
Depletion and accumulation of potassium in the extracellular clefts of cardiac Purkinje fibers during voltage clamp hyperpolarization and depolarization. Pflugers Arch (1977) 2.36
Cell communication by periodic cyclic-AMP pulses. Philos Trans R Soc Lond B Biol Sci (1975) 2.34
Intracellular calcium ions modulate acetylcholine-induced inward current in guinea-pig ileum. J Physiol (1990) 2.31
Coordination of flagella on filamentous cells of Escherichia coli. J Bacteriol (1983) 2.28
Membrane bending modulus and adhesion energy of wild-type and mutant cells of Dictyostelium lacking talin or cortexillins. Biophys J (1998) 2.24
Short-term binding and hydrolysis of cyclic 3':5'-adenosine monophosphate by aggregating Dictyostelium cells. Proc Natl Acad Sci U S A (1974) 2.22
Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase. EMBO J (1997) 2.20
Coronin, an actin binding protein of Dictyostelium discoideum localized to cell surface projections, has sequence similarities to G protein beta subunits. EMBO J (1991) 2.20
Membrane-bound cyclic AMP phosphodiesterase in chemotactically responding cells of Dictyostelium discoideum. Eur J Biochem (1972) 2.19
Specific inhibition of cell contact formation in Dictyostelium by univalent antibodies. Exp Cell Res (1970) 2.15
Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation. J Cell Biol (1999) 2.14
Calcium currents of cesium loaded isolated smooth muscle cells (urinary bladder of the guinea pig). Pflugers Arch (1985) 2.14
Chemotactic reorientation of granulocytes stimulated with micropipettes containing fMet-Leu-Phe. J Cell Sci (1981) 2.12
Dictyostelium mutants lacking the cytoskeletal protein coronin are defective in cytokinesis and cell motility. J Cell Biol (1993) 2.12
Cyclic AMP and other signals controlling cell development and differentiation in Dictyostelium. Annu Rev Biochem (1987) 2.11
Dictyostelium amoebae that lack G-actin-sequestering profilins show defects in F-actin content, cytokinesis, and development. Cell (1994) 2.10
Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells. Nature (1975) 2.05
Effect of membrane potential on acetylcholine-induced inward current in guinea-pig ileum. J Physiol (1990) 2.02
Myosin II-independent processes in mitotic cells of Dictyostelium discoideum: redistribution of the nuclei, re-arrangement of the actin system and formation of the cleavage furrow. J Cell Sci (1997) 1.99
Cortexillins, major determinants of cell shape and size, are actin-bundling proteins with a parallel coiled-coil tail. Cell (1996) 1.98
Cell aggregation and differentiation in Dictyostelium. Curr Top Dev Biol (1968) 1.96
The collection of the motile population of cells from a living tumor. Cancer Res (2000) 1.95
Severin, gelsolin, and villin share a homologous sequence in regions presumed to contain F-actin severing domains. J Biol Chem (1988) 1.91
The effect of dihydro-ouabain and lithium-ions on the outward current in cardiac Purkinje fibers. Evidence for electrogenicity of active transport. Pflugers Arch (1974) 1.91
Regulation of protrusion shape and adhesion to the substratum during chemotactic responses of mammalian carcinoma cells. Exp Cell Res (1998) 1.91
Redundancy in the microfilament system: abnormal development of Dictyostelium cells lacking two F-actin cross-linking proteins. Cell (1992) 1.89
Isolated atrial myocytes: adenosine and acetylcholine increase potassium conductance. Am J Physiol (1983) 1.86
Calcium-sensitive non-muscle alpha-actinin contains EF-hand structures and highly conserved regions. FEBS Lett (1987) 1.86
Cytoplasmic actomyosin fibrils in tissue culture cells: direct proof of contractility by visualization of ATP-induced contraction in fibrils isolated by laser micro-beam dissection. Cell Tissue Res (1976) 1.84
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway. J Biol Chem (1999) 1.82
Total and free myoplasmic calcium during a contraction cycle: x-ray microanalysis in guinea-pig ventricular myocytes. J Physiol (1991) 1.79
Quantitative analysis of cell motility and chemotaxis in Dictyostelium discoideum by using an image processing system and a novel chemotaxis chamber providing stationary chemical gradients. J Cell Biol (1989) 1.78
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocr Rev (1999) 1.78
Membrane potential modulates inositol 1,4,5-trisphosphate-mediated Ca2+ transients in guinea-pig coronary myocytes. J Physiol (1993) 1.77
Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their relation to morphogenetic cell interactions. Proc Natl Acad Sci U S A (1974) 1.77
Acetylcholine activates nonselective cation channels in guinea pig ileum through a G protein. Am J Physiol (1990) 1.77
Contribution of Ca(2+)-induced Ca2+ release to the [Ca2+]i transients in myocytes from guinea-pig urinary bladder. J Physiol (1992) 1.75
Electron microscopic mapping of monoclonal antibodies on the tail region of Dictyostelium myosin. EMBO J (1982) 1.75
Depolarization-mediated intracellular calcium transients in isolated smooth muscle cells of guinea-pig urinary bladder. J Physiol (1991) 1.74
Contribution of two types of calcium channels to membrane conductance of single myocytes from guinea-pig coronary artery. J Physiol (1990) 1.72
Ca2+ load of guinea-pig ventricular myocytes determines efficacy of brief Ca2+ currents as trigger for Ca2+ release. J Physiol (1994) 1.71
Carbohydrate and other epitopes of the contact site A glycoprotein of Dictyostelium discoideum as characterized by monoclonal antibodies. Cell Differ (1985) 1.71
A role for myosin VII in dynamic cell adhesion. Curr Biol (2001) 1.71
Ca2+ activation and Ca2+ inactivation of canine reconstituted cardiac sarcoplasmic reticulum Ca(2+)-release channels. J Physiol (1995) 1.71
Structural characterization of a higher plant calmodulin : spinacia oleracea. Plant Physiol (1984) 1.69
New actin-binding proteins from Dictyostelium discoideum. EMBO J (1984) 1.68
Cyclic GMP in Dictyostelium discoideum, Oscillations and pulses in response to folic acid and cyclic AMP signals. FEBS Lett (1977) 1.68
The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension. Curr Biol (2001) 1.62
The hybrid histidine kinase DokA is part of the osmotic response system of Dictyostelium. EMBO J (1996) 1.62
Conformation of thymosin beta 4 in water determined by NMR spectroscopy. Eur J Biochem (1993) 1.62
A distinct 14 residue site triggers coiled-coil formation in cortexillin I. EMBO J (1998) 1.61
Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position. EMBO J (1999) 1.59
Decoupling of heart muscle cells: correlation with increased cytoplasmic calcium activity and with changes of nexus ultrastructure. J Membr Biol (1980) 1.58
Cardiac Purkinje fibres: [Ca2+]i controls the potassium permeability via the conductance components gK1 and gK2. Pflugers Arch (1977) 1.57
Selection of Dictyostelium mutants defective in cytoskeletal proteins: use of an antibody that binds to the ends of alpha-actinin rods. EMBO J (1986) 1.56
Complete sequence and transcript regulation of a cell adhesion protein from aggregating Dictyostelium cells. EMBO J (1986) 1.55
Protection against osmotic stress by cGMP-mediated myosin phosphorylation. Science (1996) 1.55
Amplification of cyclic-AMP signals in aggregating cells of Dictyostelium discoideum. FEBS Lett (1975) 1.54
Gating of maxi K+ channels studied by Ca2+ concentration jumps in excised inside-out multi-channel patches (myocytes from guinea pig urinary bladder). J Gen Physiol (1992) 1.52
The actin cytoskeleton of Dictyostelium: a story told by mutants. J Cell Sci (2000) 1.51
Receptor-mediated adenylate cyclase activation in Dictyostelium discoideum. FEBS Lett (1976) 1.51
Disruption of microfilament organization after injection of F-actin capping proteins into living tissue culture cells. Nature (1983) 1.49
Cell motility of tumor cells visualized in living intact primary tumors using green fluorescent protein. Cancer Res (1998) 1.49
Talin-null cells of Dictyostelium are strongly defective in adhesion to particle and substrate surfaces and slightly impaired in cytokinesis. J Cell Biol (1997) 1.49
Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily. J Cell Sci (2001) 1.49
A micromechanic study of cell polarity and plasma membrane cell body coupling in Dictyostelium. Biophys J (2000) 1.48