Published in Pflugers Arch on September 30, 1976
Voltage-dependent inactivation of inward-rectifying single-channel currents in the guinea-pig heart cell membrane. J Physiol (1984) 4.08
The surprising heart: a review of recent progress in cardiac electrophysiology. J Physiol (1984) 3.18
A new interpretation of the pace-maker current in calf Purkinje fibres. J Physiol (1981) 3.05
Ionic basis of transient inward current induced by strophanthidin in cardiac Purkinje fibres. J Physiol (1978) 2.94
Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophys J (1995) 2.43
Voltage-dependent activation of the inward-rectifier potassium channel in the ventricular cell membrane of guinea-pig heart. J Physiol (1985) 2.29
The Mg2+ block and intrinsic gating underlying inward rectification of the K+ current in guinea-pig cardiac myocytes. J Physiol (1989) 2.23
4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers. J Gen Physiol (1979) 2.12
Calcium-mediated inactivation of the calcium conductance in cesium-loaded frog heart cells. J Gen Physiol (1984) 2.11
An intrinsic potential-dependent inactivation mechanism associated with calcium channels in guinea-pig myocytes. J Physiol (1987) 2.04
Block and activation of the pace-maker channel in calf purkinje fibres: effects of potassium, caesium and rubidium. J Physiol (1982) 1.98
Properties of the current if in the sino-atrial node of the rabbit compared with those of the current iK, in Purkinje fibres. J Physiol (1980) 1.87
The role of the sodium pump in the effects of potassium-depleted solutions on mammalian cardiac muscle. J Physiol (1979) 1.56
Potassium currents in frog ventricular muscle: evidence from voltage clamp currents and extracellular K accumulation. J Physiol (1979) 1.54
Influence of chloride, potassium, and tetraethylammonium on the early outward current of sheep cardiac Purkinje fibers. J Gen Physiol (1979) 1.48
Membrane currents and their modification by acetylcholine in isolated single atrial cells of the guinea-pig. J Physiol (1985) 1.45
Slow inactivation of a tetrodotoxin-sensitive current in canine cardiac Purkinje fibers. Biophys J (1984) 1.36
Characterization of the acetylcholine-induced potassium current in rabbit cardiac Purkinje fibres. J Physiol (1986) 1.34
The mechanism of rectification of iK1 in canine Purkinje myocytes. J Gen Physiol (1990) 1.28
Potential and tension changes induced by sodium removal in dog Purkinje fibres: role of an electrogenic sodium-calcium exchange. J Physiol (1981) 1.27
Characterization of the pace-maker current kinetics in calf Purkinje fibres. J Physiol (1984) 1.25
Delayed rectification in the calf cardiac Purkinje fiber. Evidence for multiple state kinetics. Biophys J (1985) 1.20
Actions of barium and rubidium on membrane currents in canine Purkinje fibres. J Physiol (1983) 1.19
Serotonin increases an anomalously rectifying K+ current in the Aplysia neuron R15. Proc Natl Acad Sci U S A (1983) 1.07
Background K+ current in isolated canine cardiac Purkinje myocytes. Biophys J (1987) 1.05
The reversible replacement of internal potassium by caesium in isolated turtle heart. J Physiol (1979) 1.00
Ionic currents responsible for the generation of pace-maker current in the rabbit sino-atrial node. J Physiol (1984) 0.99
Unitary conductance variation in Kir2.1 and in cardiac inward rectifier potassium channels. Biophys J (2001) 0.99
Depletion and accumulation of potassium in the extracellular clefts of cardiac Purkinje fibers during voltage clamp hyperpolarization and depolarization: experiments in sodium-free bathing media. J Gen Physiol (1977) 0.98
Spontaneous fluctuations of potassium channels in the apical membrane of frog skin. J Physiol (1980) 0.97
Patch-clamp analysis in canine cardiac Purkinje cells of a novel sodium component in the pacemaker range. J Physiol (2003) 0.96
Role of the anomalous rectifier in determining membrane potentials of mouse muscle fibres at low extracellular K+. J Physiol (1991) 0.94
Potassium channel blockade: A mechanism for suppressing ventricular fibrillation. Proc Natl Acad Sci U S A (1986) 0.93
The role of the Na(+)-Ca2+ exchanger in the rate-dependent increase in contraction in guinea-pig ventricular myocytes. J Physiol (1995) 0.91
Interaction of potassium channel openers and blockers in canine atrial muscle. Br J Pharmacol (1989) 0.88
Cesium blockade of delayed outward currents and electrically induced pacemaker activity in mammalian ventricular myocardium. J Gen Physiol (1981) 0.88
The electrophysiological effects of dicentrine on the conduction system of rabbit heart. Br J Pharmacol (1994) 0.85
Characterization of the effects of the new inotropic agent BDF 9148 in isolated papillary muscles and myocytes of the guinea-pig heart. Br J Pharmacol (1991) 0.82
Electrophysiological effects of the salicylates on isolated atrial muscle of the rabbit. Br J Pharmacol (1982) 0.82
Mechanism by which metabolic inhibitors depolarize cultured cardiac cells. Proc Natl Acad Sci U S A (1983) 0.82
Effects of pinacidil, verapamil, and heart rate on afterdepolarizations in the guinea-pig heart in vivo. Heart Vessels (1996) 0.82
Mechanical and electrophysiological studies on the positive inotropic effect of 2-phenyl-4-oxo-hydroquinoline in rat cardiac tissues. Br J Pharmacol (1993) 0.80
Characterization of the interaction of R 56865 with cardiac Na- and L-type Ca channels. Br J Pharmacol (1991) 0.80
Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization. J Mol Cell Cardiol (2015) 0.79
Inhibition of the myocardial Ca(2+)-current (ICa) by the enantiomers of DPI 201-106 and BDF 8784. Br J Pharmacol (1991) 0.79
Effects of thallium on membrane currents at diastolic potentials in canine cardiac Purkinje strands. J Physiol (1986) 0.77
Inward-rectifier K+ current in guinea-pig ventricular myocytes exposed to hyperosmotic solutions. J Membr Biol (2004) 0.76
Analysis of the hyperpolarizing effect of catecholamines on canine cardiac Purkinje fibres. Br J Pharmacol (1989) 0.75
Alkali cation permeability and caesium blockade of cromakalim-activated current in guinea-pig ventricular myocytes. Br J Pharmacol (1991) 0.75
Differential effects of extracellular cesium on early afterdepolarizations in ventricular myocytes and arrhythmogenesis in isolated hearts of rats and guinea pigs. Pflugers Arch (2004) 0.75
Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium". Pflugers Arch (1982) 6.81
Superresolution three-dimensional images of fluorescence in cells with minimal light exposure. Science (1995) 4.16
Polarity of actin at the leading edge of cultured cells. Nature (1978) 3.40
Action potentials and net membrane currents of isolated smooth muscle cells (urinary bladder of the guinea-pig). Pflugers Arch (1985) 3.12
An actin-binding protein from Acanthamoeba regulates actin filament polymerization and interactions. Nature (1980) 3.04
Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation. Proc Natl Acad Sci U S A (1981) 2.84
Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude. Pflugers Arch (1982) 2.69
Depletion and accumulation of potassium in the extracellular clefts of cardiac Purkinje fibers during voltage clamp hyperpolarization and depolarization. Pflugers Arch (1977) 2.36
Intracellular calcium ions modulate acetylcholine-induced inward current in guinea-pig ileum. J Physiol (1990) 2.31
Calcium currents of cesium loaded isolated smooth muscle cells (urinary bladder of the guinea pig). Pflugers Arch (1985) 2.14
Effect of membrane potential on acetylcholine-induced inward current in guinea-pig ileum. J Physiol (1990) 2.02
The effect of dihydro-ouabain and lithium-ions on the outward current in cardiac Purkinje fibers. Evidence for electrogenicity of active transport. Pflugers Arch (1974) 1.91
Isolated atrial myocytes: adenosine and acetylcholine increase potassium conductance. Am J Physiol (1983) 1.86
Cytoplasmic actomyosin fibrils in tissue culture cells: direct proof of contractility by visualization of ATP-induced contraction in fibrils isolated by laser micro-beam dissection. Cell Tissue Res (1976) 1.84
Total and free myoplasmic calcium during a contraction cycle: x-ray microanalysis in guinea-pig ventricular myocytes. J Physiol (1991) 1.79
Membrane potential modulates inositol 1,4,5-trisphosphate-mediated Ca2+ transients in guinea-pig coronary myocytes. J Physiol (1993) 1.77
Acetylcholine activates nonselective cation channels in guinea pig ileum through a G protein. Am J Physiol (1990) 1.77
Contribution of Ca(2+)-induced Ca2+ release to the [Ca2+]i transients in myocytes from guinea-pig urinary bladder. J Physiol (1992) 1.75
Depolarization-mediated intracellular calcium transients in isolated smooth muscle cells of guinea-pig urinary bladder. J Physiol (1991) 1.74
Contribution of two types of calcium channels to membrane conductance of single myocytes from guinea-pig coronary artery. J Physiol (1990) 1.72
Ca2+ load of guinea-pig ventricular myocytes determines efficacy of brief Ca2+ currents as trigger for Ca2+ release. J Physiol (1994) 1.71
Ca2+ activation and Ca2+ inactivation of canine reconstituted cardiac sarcoplasmic reticulum Ca(2+)-release channels. J Physiol (1995) 1.71
New actin-binding proteins from Dictyostelium discoideum. EMBO J (1984) 1.68
Decoupling of heart muscle cells: correlation with increased cytoplasmic calcium activity and with changes of nexus ultrastructure. J Membr Biol (1980) 1.58
Cardiac Purkinje fibres: [Ca2+]i controls the potassium permeability via the conductance components gK1 and gK2. Pflugers Arch (1977) 1.57
Selection of Dictyostelium mutants defective in cytoskeletal proteins: use of an antibody that binds to the ends of alpha-actinin rods. EMBO J (1986) 1.56
Gating of maxi K+ channels studied by Ca2+ concentration jumps in excised inside-out multi-channel patches (myocytes from guinea pig urinary bladder). J Gen Physiol (1992) 1.52
Disruption of microfilament organization after injection of F-actin capping proteins into living tissue culture cells. Nature (1983) 1.49
Microheterogeneity of subsarcolemmal sodium gradients. Electron probe microanalysis in guinea-pig ventricular myocytes. J Physiol (1993) 1.46
Crystalline actin sheets: their structure and polymorphism. J Cell Biol (1981) 1.40
A Dictyostelium mutant deficient in severin, an F-actin fragmenting protein, shows normal motility and chemotaxis. J Cell Biol (1989) 1.40
Intracellular [Ca2+] transients in voltage clamped cardiac Purkinje fibers. Pflugers Arch (1982) 1.39
Cardiac Purkinje fibres: [Ca2+]i controls steady state potassium conductance. Pflugers Arch (1977) 1.39
Actions of adenosine and isoproterenol on isolated mammalian ventricular myocytes. Circ Res (1983) 1.37
The viscoelasticity of entangled actin networks: the influence of defects and modulation by talin and vinculin. Eur Biophys J (1993) 1.36
Glycocalyx is not required for show inward calcium current in isolated rat heart myocytes. Nature (1980) 1.36
Structural aspects of vinculin-actin interactions. J Mol Biol (1982) 1.35
Ca2+ influx through ATP-gated channels increments [Ca2+]i and inactivates ICa in myocytes from guinea-pig urinary bladder. J Physiol (1991) 1.34
Intracellular pH modulates the availability of vascular L-type Ca2+ channels. J Gen Physiol (1994) 1.32
Ca entry and contraction as studied in isolated bovine ventricular myocytes. Z Naturforsch C (1982) 1.30
Calcium channel current of vascular smooth muscle cells: extracellular protons modulate gating and single channel conductance. J Gen Physiol (1994) 1.29
Endothelin depolarizes myocytes from porcine coronary and human mesenteric arteries through a Ca-activated chloride current. Pflugers Arch (1991) 1.29
The shortening of the action potential by DNP in guinea-pig ventricular myocytes is mediated by an increase of a time-independent K conductance. Pflugers Arch (1983) 1.27
K efflux through inward rectifying K channels in voltage clamped Purkinje fibers. Pflugers Arch (1980) 1.27
Analysis of filamin and alpha-actinin binding to actin by the stopped flow method. FEBS Lett (1993) 1.25
The role of sodium channels in the effects of the cardiotonic compound DPI 201-106 on contractility and membrane potentials in isolated mammalian heart preparations. Eur J Pharmacol (1985) 1.25
A Dictyostelium mutant lacking an F-actin cross-linking protein, the 120-kD gelation factor. J Cell Biol (1990) 1.24
Talin anchors and nucleates actin filaments at lipid membranes. A direct demonstration. FEBS Lett (1992) 1.22
Experimental approach to test the role of actin in axonal transport. Brain Res (1980) 1.21
Cardiac Purkinje fibres: resting, action, and pacemaker potential under the influence of [Ca2+]i as modified by intracellular injection techniques. Pflugers Arch (1977) 1.20
Native talin is a dumbbell-shaped homodimer when it interacts with actin. J Struct Biol (1994) 1.20
X-ray microanalysis of single cardiac myocytes frozen under voltage-clamp conditions. Am J Physiol (1989) 1.19
Stretch-activated currents in ventricular myocytes: amplitude and arrhythmogenic effects increase with hypertrophy. Cardiovasc Res (2000) 1.19
Actin filament capping protein from bovine brain. EMBO J (1982) 1.18
Ionic basis for the antagonism between adenosine and isoproterenol on isolated mammalian ventricular myocytes. Circ Res (1984) 1.18
Talin binds to actin and promotes filament nucleation. FEBS Lett (1991) 1.17
Transformation of cytoplasmic actin. Importance for the organization of the contractile gel reticulum and the contraction--relasation cycle of cytoplasmic actomyosin. Cell Tissue Res (1976) 1.17
Calcium-induced calcium release in rat sensory neurons. J Physiol (1995) 1.17
Caffeine-induced release and reuptake of Ca2+ by Ca2+ stores in myocytes from guinea-pig urinary bladder. J Physiol (1992) 1.16
Mechanical deformation of ventricular myocytes modulates both TRPC6 and Kir2.3 channels. Cell Calcium (2008) 1.16
A Dictyostelium mutant with severe defects in alpha-actinin: its characterization using cDNA probes and monoclonal antibodies. J Cell Sci (1988) 1.15
Tension-voltage relations of single myocytes reflect Ca release triggered by Na/Ca exchange at 35 degrees C but not 23 degrees C. Am J Physiol (1994) 1.15
Stretch effects on whole-cell currents of guinea-pig urinary bladder myocytes. J Physiol (1994) 1.14
Properties of stretch-activated channels in myocytes from the guinea-pig urinary bladder. J Physiol (1993) 1.14
Efficacy of peak Ca2+ currents (ICa) as trigger of sarcoplasmic reticulum Ca2+ release in myocytes from the guinea-pig coronary artery. J Physiol (1995) 1.13
Isolated bovine ventricular myocytes. Characterization of the action potential. Pflugers Arch (1982) 1.13
Dissociation of subsarcolemmal from global cytosolic [Ca2+] in myocytes from guinea-pig coronary artery. J Physiol (1996) 1.13
Sustained subthreshold-for-twitch depolarization in rat single ventricular myocytes causes sustained calcium channel activation and sarcoplasmic reticulum calcium release. J Gen Physiol (1990) 1.12
12-fold difference between the critical monomer concentrations of the two ends of actin filaments in physiological salt conditions. Proc Natl Acad Sci U S A (1983) 1.11
Identification of functional domains in the cytoskeletal protein talin. Eur J Biochem (1994) 1.11
Cardiac Purkinje fibres: the slow inward current component under the influence of modified [Ca2+]i. Pflugers Arch (1977) 1.11
The effect of intact talin and talin tail fragment on actin filament dynamics and structure depends on pH and ionic strength. Eur J Biochem (1999) 1.09
Pharmacological modulation of calcium and potassium channels in isolated vascular smooth muscle cells. Arzneimittelforschung (1989) 1.08
Structure of crystalline actin sheets. Nature (1980) 1.08
How can overexpression of Na(+),Ca(2+)-exchanger compensate the negative inotropic effects of downregulated SERCA? Cardiovasc Res (2001) 1.07
The effects of the Anemonia sulcata toxin (ATX II) on membrane currents of isolated mammalian myocytes. J Physiol (1984) 1.07
Force measurements from voltage-clamped guinea pig ventricular myocytes. Am J Physiol (1990) 1.07
Ca2+-activated K+ channels contribute to the resting potential of vascular myocytes. Ca2+-sensitivity is increased by intracellular Mg2+-ions. Pflugers Arch (1989) 1.07
Mechanisms underlying enhanced cardiac excitation contraction coupling observed in the senescent sheep myocardium. J Mol Cell Cardiol (2004) 1.06
Use of guanylyl cyclase C for detecting micrometastases in lymph nodes of patients with colon cancer. Dis Colon Rectum (1998) 1.05
Calmodulin antagonists depress calcium and potassium currents in ventricular and vascular myocytes. Am J Physiol (1987) 1.04
Isolated guinea pig coronary smooth muscle cells. Acetylcholine induces hyperpolarization due to sarcoplasmic reticulum calcium release activating potassium channels. Circ Res (1990) 1.04
High-resolution endoscopic imaging of the GI tract: a comparative study of optical coherence tomography versus high-frequency catheter probe EUS. Gastrointest Endosc (2001) 1.04
Vinculin and alpha-actinin: interaction with actin and effect on microfilament network formation. Cold Spring Harb Symp Quant Biol (1982) 1.01
Ca-antagonistic effects of adenosine in guinea pig atrial cells. Am J Physiol (1988) 0.99
Inotropic response to beta-adrenergic receptor stimulation and anti-adrenergic effect of ACh in endothelial NO synthase-deficient mouse hearts. J Physiol (2001) 0.99
Depletion and accumulation of potassium in the extracellular clefts of cardiac Purkinje fibers during voltage clamp hyperpolarization and depolarization: experiments in sodium-free bathing media. J Gen Physiol (1977) 0.98
Cytochalasin D reduces Ca2+ currents via cofilin-activated depolymerization of F-actin in guinea-pig cardiomyocytes. J Physiol (2001) 0.98
Interaction of the 47-kDa talin fragment and the 32-kDa vinculin fragment with acidic phospholipids: a computer analysis. Biophys J (1995) 0.97
The alpha subunit of the GTP binding protein activates muscarinic potassium channels of the atrium. Science (1988) 0.96
Buffering of plasmalemmal Ca2+ current by sarcoplasmic reticulum of guinea pig urinary bladder myocytes. Am J Physiol (1996) 0.95
Tiapamil reduces the calcium inward current of isolated smooth muscle cells. Dependence on holding potential and pulse frequency. Eur J Pharmacol (1986) 0.95
Viscoelasticity of actin-gelsolin networks in the presence of filamin. Eur J Biochem (1997) 0.94
Extra- and intracellular lanthanum: modified calcium distribution, inward currents and contractility in guinea pig ventricular preparations. Pflugers Arch (1985) 0.94
Ca2+ entry through Na(+)-Ca2+ exchange can trigger Ca2+ release from Ca2+ stores in Na(+)-loaded guinea-pig coronary myocytes. J Physiol (1993) 0.93
Effect of imipramine on calcium and potassium currents in isolated bovine ventricular myocytes. Eur J Pharmacol (1985) 0.93
Cell surgery by laser micro-dissection: a preparative method. J Microsc (1976) 0.93
Temperature sensitivity of outward current in cardiac Purkinje fibers. Evidence of electrogenicity of active transport. Pflugers Arch (1975) 0.92
L-type Ca-channels: similar Q10 of Ca-, Ba- and Na-conductance points to the importance of ion-channel interaction. Pflugers Arch (1990) 0.92
ATP suppresses activity of Ca(2+)-activated K+ channels by Ca2+ chelation. Pflugers Arch (1992) 0.91