Published in Science on May 05, 1972
The gradient-sensing mechanism in bacterial chemotaxis. Proc Natl Acad Sci U S A (1972) 17.36
Calcium control of waveform in isolated flagellar axonemes of Chlamydomonas. J Cell Biol (1980) 2.92
CatSper1 required for evoked Ca2+ entry and control of flagellar function in sperm. Proc Natl Acad Sci U S A (2003) 2.34
Calcium-induced asymmetrical beating of triton-demembranated sea urchin sperm flagella. J Cell Biol (1979) 2.17
Striated flagellar roots: isolation and partial characterization of a calcium-modulated contractile organelle. J Cell Biol (1984) 2.15
Localization of calcium channels in Paramecium caudatum. J Physiol (1977) 2.13
Microtubule-membrane interactions in cilia. II. Photochemical cross-linking of bridge structures and the identification of a membrane-associated dynein-like ATPase. J Cell Biol (1980) 1.65
A conserved CaM- and radial spoke associated complex mediates regulation of flagellar dynein activity. J Cell Biol (2007) 1.38
Calcium-dependent repolarization in Paramecium. J Physiol (1978) 1.36
Spontaneous creation of macroscopic flow and metachronal waves in an array of cilia. Biophys J (2006) 1.32
Regulation of flagellar dynein by calcium and a role for an axonemal calmodulin and calmodulin-dependent kinase. Mol Biol Cell (2002) 1.30
Synchronous exocytosis in Paramecium cells involves very rapid (less than or equal to 1 s), reversible dephosphorylation of a 65-kD phosphoprotein in exocytosis-competent strains. J Cell Biol (1985) 1.30
Calcium control of ciliary arrest in mussel gill cells. J Cell Biol (1978) 1.29
Differential regulation of Paramecium ciliary motility by cAMP and cGMP. J Cell Biol (1988) 1.28
Purinergic stimulation of rabbit ciliated airway epithelia: control by multiple calcium sources. J Physiol (1996) 1.23
Similarities and dissimilarities between calmodulin and a Chlamydomonas flagellar protein. Proc Natl Acad Sci U S A (1980) 1.22
Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum. J Biol Chem (2008) 1.19
Electrophysiological control of reversed ciliary beating in Paramecium. J Gen Physiol (1973) 1.19
Simultaneous measurement of ciliary beating and intracellular calcium. Biophys J (1994) 1.14
Bend propagation drives central pair rotation in Chlamydomonas reinhardtii flagella. J Cell Biol (2004) 1.14
Mode of Ca2+ action on ciliary beat frequency in single ovine airway epithelial cells. J Physiol (1999) 1.11
Motile detergent-extracted cells of Tetrahymena and Chlamydomonas. J Cell Biol (1983) 1.10
Presence and indirect immunofluorescent localization of calmodulin in Paramecium tetraurelia. J Cell Biol (1981) 1.10
The role of cortical orientation in the control of the direction of ciliary beat in Paramecium. J Cell Biol (1975) 1.07
ATP keeps exocytosis sites in a primed state but is not required for membrane fusion: an analysis with Paramecium cells in vivo and in vitro. J Cell Biol (1986) 1.03
Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Mol Biol Cell (2011) 1.03
Control of tumbling in bacterial chemotaxis by divalent cation. J Bacteriol (1976) 1.02
The rate of change in Ca(2+) concentration controls sperm chemotaxis. J Cell Biol (2012) 1.02
Nonbehavioral selection for pawns, mutants of Paramecium aurelia with decreased excitability. Genetics (1976) 1.00
Calmodulin antagonists inhibit secretion in Paramecium. J Cell Biol (1983) 0.99
Calcium ion regulation of chirality of beating flagellum of reactivated sea urchin spermatozoa. Biophys J (1993) 0.99
The CSC connects three major axonemal complexes involved in dynein regulation. Mol Biol Cell (2012) 0.98
Intra- and interspecific complementation of membrane-inexcitable mutants of Paramecium. J Cell Biol (1983) 0.98
Chlamydomonas outer arm dynein alters conformation in response to Ca2+. Mol Biol Cell (2007) 0.97
How 5000 independent rowers coordinate their strokes in order to row into the sunlight: phototaxis in the multicellular green alga Volvox. BMC Biol (2010) 0.97
Divalent cation affinity sites in Paramecium aurelia. J Cell Biol (1976) 0.92
A calcium regenerative potential controlling ciliary reversal is propagated along the length of ctenophore comb plates. Proc Natl Acad Sci U S A (1987) 0.89
Membrane excitability: made temperature-dependent by mutations. Proc Natl Acad Sci U S A (1974) 0.88
Calcium control of ciliary reversal in ionophore-treated and ATP-reactivated comb plates of ctenophores. J Cell Biol (1985) 0.88
Organic anions stabilize the reactivated motility of sperm flagella and the latency of dynein 1 ATPase activity. J Cell Biol (1985) 0.88
Responses of the ciliates Tetrahymena and Paramecium to external ATP and GTP. Purinergic Signal (2005) 0.88
An electrophysiological study of the regulation of ciliary beating frequency in Paramecium. J Physiol (1978) 0.87
Outer dynein arm light chain 1 is essential for controlling the ciliary response to cyclic AMP in Paramecium tetraurelia. Eukaryot Cell (2012) 0.86
Ion channels and calcium signaling in motile cilia. Elife (2015) 0.84
Attempts to retreat from a dead-ended long capillary by backward swimming in Paramecium. Front Microbiol (2014) 0.84
Inseparable tandem: evolution chooses ATP and Ca2+ to control life, death and cellular signalling. Philos Trans R Soc Lond B Biol Sci (2016) 0.82
New mutants of Paramecium tetraurelia defective in a calcium control mechanism: genetic and behavioral characterizations. Genetics (1989) 0.82
Tubulin-dynein system in flagellar and ciliary movement. Proc Jpn Acad Ser B Phys Biol Sci (2012) 0.81
Calcium sensors of ciliary outer arm dynein: functions and phylogenetic considerations for eukaryotic evolution. Cilia (2015) 0.80
The cilia of Paramecium tetraurelia contain both Ca2+-dependent and Ca2+-inhibitable calmodulin-binding proteins. Biochem J (1989) 0.80
Antibodies to the ciliary membrane of Paramecium tetraurelia alter membrane excitability. J Cell Biol (1983) 0.80
Purinergically induced membrane fluidization in ciliary cells: characterization and control by calcium and membrane potential. Biophys J (1996) 0.80
Migratory cell locomotion versus nerve axon elongation: differences based on the effects of lanthanum ion. J Cell Biol (1974) 0.79
Effects of divalent and lanthanide ions on motility initiation in rat caudal epididymal spermatozoa. Br J Pharmacol (1981) 0.76
K+-induced Ca2+ conductance responsible for the prolonged backward swimming in K+-agitated mutant of Paramecium caudatum. J Membr Biol (2003) 0.76
Ionic currents of channels that are permeable to monovalent and divalent cations. Biophys J (1989) 0.76
Different properties of two voltage-dependent inward currents of the ciliate Stylonychia mytilus. J Physiol (1986) 0.75
Novel Insights into the Development and Function of Cilia Using the Advantages of the Paramecium Cell and Its Many Cilia. Cells (2015) 0.75
An autocrine ATP release mechanism regulates basal ciliary activity in airway epithelium. J Physiol (2017) 0.75
Behavioral Effects of a Chemorepellent Receptor Knockout Mutation in Tetrahymena thermophila. mSphere (2017) 0.75
Inactivation of Ca2+-induced ciliary reversal by high-salt extraction in the cilia of Paramecium. Protoplasma (2013) 0.75
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia (1996) 5.06
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81
Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity. Cancer Res (2001) 3.51
Biological and Immunological Properties of Encapsulated Strains of Staphylococcus aureus from Human Sources. Infect Immun (1970) 2.68
Expression of the Fas ligand in cells of T cell lineage. J Immunol (1995) 2.54
A new technique for monitoring the behaviour of free-ranging Adélie penguins. J Exp Biol (2001) 2.24
Penguin-mounted cameras glimpse underwater group behaviour. Proc Biol Sci (2004) 2.15
NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus. Mol Cell Biol (1995) 2.13
Buoyancy and maximal diving depth in penguins: do they control inhaling air volume? J Exp Biol (2002) 2.12
Randomised clinical trial: rabeprazole improves symptoms in patients with functional dyspepsia in Japan. Aliment Pharmacol Ther (2013) 2.08
Precise monitoring of porpoising behaviour of Adélie penguins determined using acceleration data loggers. J Exp Biol (1999) 2.00
Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production. J Biol Chem (1999) 1.98
Control of ciliary activities by adenosinetriphosphate and divalent cations in triton-extracted models of Paramecium caudatum. J Exp Biol (1973) 1.91
Reduced interferon gamma production by antigen-stimulated cord blood mononuclear cells is a risk factor of allergic disorders--6-year follow-up study. Clin Exp Allergy (1998) 1.86
Role of interleukin-18 (IL-18) in mycobacterial infection in IL-18-gene-disrupted mice. Infect Immun (1999) 1.85
Purification and properties of hemagglutinin from culture supernatant of Bacteroides gingivalis. Infect Immun (1986) 1.85
Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage. Nucleic Acids Res (1989) 1.81
Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis. Br J Cancer (2004) 1.80
Ductal aneurysm of adult patients. Jpn J Thorac Cardiovasc Surg (2000) 1.78
Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats. Gut (1993) 1.75
Muscarinic acetylcholine receptor autoantibodies in patients with Sjögren's syndrome. Ann Rheum Dis (2005) 1.61
International prognostic scoring system and TP53 mutations are independent prognostic indicators for patients with myelodysplastic syndrome. Br J Haematol (2001) 1.59
Intrapleural administration of a large amount of diluted fibrin glue for intractable pneumothorax. Chest (2000) 1.59
Swimming speeds and buoyancy compensation of migrating adult chum salmon Oncorhynchus keta revealed by speed/depth/acceleration data logger. J Exp Biol (2001) 1.57
Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors. Cancer Res (1994) 1.55
A new mechanism for anti-inflammatory actions of proton pump inhibitors--inhibitory effects on neutrophil-endothelial cell interactions. Aliment Pharmacol Ther (2000) 1.48
Quantitative analyses of messenger RNA of human endogenous retrovirus in patients with systemic lupus erythematosus. J Rheumatol (2001) 1.45
Reduced IFNgamma production in response to IL-12 stimulation and/or reduced IL-12 production in atopic patients. Clin Exp Allergy (2000) 1.44
Thermosensitive mutant of Escherichia coli requiring new protein synthesis to recover cellular division ability. Biochem Biophys Res Commun (1971) 1.43
Effect of intravenous cyclophosphamide in systemic lupus erythematosus: relation to lymphocyte subsets and activation markers. Lupus (2000) 1.43
Is inactivation of the p53 gene a common event in leukemias and myelodysplastic syndrome with monosomy 17p? Leukemia (1994) 1.42
Asymptomatic hyponatremia due to inappropriate secretion of antidiuretic hormone as the first sign of a small cell lung cancer in an elderly man. Intern Med (1998) 1.42
Inhibition of amyloid beta protein aggregation and neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger. J Biol Chem (1996) 1.42
Reticulate hyperpigmentation distributed in a zosteriform fashion: a new clinical type of hyperpigmentation. Br J Dermatol (1987) 1.41
Intravital laser confocal microscopy of pulmonary edema resulting from intestinal ischemia-reperfusion injury in the rat. Crit Care Med (1999) 1.40
High speed clinical data retrieval system with event time sequence feature: with 10 years of clinical data of Hamamatsu University Hospital CPOE. Methods Inf Med (2008) 1.39
Immunoglobulin G response to subgingival gram-negative bacteria in human subjects. Infect Immun (1984) 1.39
Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors. Inflamm Res (2006) 1.37
The prognosis of intraductal papillary mucinous tumors of the pancreas. Hepatogastroenterology (2001) 1.37
Norepinephrine-producing tumors of bilateral breasts: a case report. Cancer (1978) 1.35
Left main coronary trunk compression by dilated main pulmonary artery in atrial septal defect. Report of three cases. J Thorac Cardiovasc Surg (1992) 1.33
Calcium-induced ciliary reversal in the extracted models of "Pawn", a behavioral mutant of Paramecium. Science (1973) 1.32
The expression of ST2 gene in helper T cells and the binding of ST2 protein to myeloma-derived RPMI8226 cells. J Biochem (1997) 1.29
Regulation of neuronal nitric-oxide synthase by calmodulin kinases. J Biol Chem (1999) 1.29
Lipid composition of 30 species of yeast. Lipids (1976) 1.28
Endoscopic submucosal dissection for colorectal tumors: technical difficulties and rate of perforation. Endoscopy (2009) 1.28
Serum triglycerides and risk of coronary heart disease among Japanese men and women. Am J Epidemiol (2001) 1.28
Systematically missing confounders in individual participant data meta-analysis of observational cohort studies. Stat Med (2009) 1.27
E-Cell 2: multi-platform E-Cell simulation system. Bioinformatics (2003) 1.27
Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance. Arzneimittelforschung (1993) 1.23
Bacteriological study of periodontal lesions in two sisters with juvenile periodontitis and their mother. Infect Immun (1984) 1.23
Unstable resistance of G mouse fibroblasts to ecotropic murine leukemia virus infection. J Virol (1979) 1.21
Intersexual differences in the diving behaviour of foraging subantarctic cormorant (Phalacrocorax albiventer) and Japanese cormorant (P. filamentosus). C R Acad Sci III (1999) 1.21
Possible clinical and histologic manifestations of adult-onset type II citrullinemia in early infancy. J Pediatr (2001) 1.20
Monoclonal antibodies against surface antigens of Bacteroides gingivalis. Infect Immun (1985) 1.20
5'-Nucleotidase from rat heart membranes. Inhibition by adenine nucleotides and related compounds. Biochem J (1985) 1.20
Exercise capacity of thoracotomy patients in the early postoperative period. Chest (2000) 1.18
Role of oxygen-derived free radicals in gastric mucosal injury induced by ischemia or ischemia-reperfusion in rats. Free Radic Res Commun (1989) 1.18
Maturation/M-phase promoting factor: a regulator of aging in porcine oocytes. Biol Reprod (2000) 1.18
Immunophenotypic characterization of Epstein-Barr virus-associated gastric carcinoma: massive infiltration by proliferating CD8+ T-lymphocytes. Lab Invest (1996) 1.17
Fluid shear stress-induced cyclooxygenase-2 expression is mediated by C/EBP beta, cAMP-response element-binding protein, and AP-1 in osteoblastic MC3T3-E1 cells. J Biol Chem (2000) 1.17
Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia. Leukemia (1997) 1.16
Preparatory inhibition of cortico-spinal excitability: a transcranial magnetic stimulation study in man. Brain Res Cogn Brain Res (1997) 1.16
5'-Nucleotidase from rat heart. Biochemistry (1981) 1.16
The antioxidant properties of a novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-histidinato zinc. Biochim Biophys Acta (1991) 1.15
Detection of specific antibody in adult human periodontitis sera to surface antigens of Bacteroides gingivalis. Infect Immun (1987) 1.14
Cryopreservation and ensuing in vitro fertilization ability of boar spermatozoa from epididymides stored at 4 degrees C. Theriogenology (1998) 1.13
ATM is upregulated during the mitogenic response in peripheral blood mononuclear cells. Blood (1999) 1.13
Endogenous production of TGF-beta is essential for osteoclastogenesis induced by a combination of receptor activator of NF-kappa B ligand and macrophage-colony-stimulating factor. J Immunol (2000) 1.10
Interleukin-8 expression in the esophageal mucosa of patients with gastroesophageal reflux disease. Scand J Gastroenterol (2004) 1.10
Gas exchange function through the mastoid mucosa in ears after surgery. Laryngoscope (1997) 1.09
Involvement of gangliosides in glycosylphosphatidylinositol-anchored neuronal cell adhesion molecule TAG-1 signaling in lipid rafts. J Biol Chem (2000) 1.09
A novel single-nucleotide polymorphism at the 5'-flanking region of SAA1 associated with risk of type AA amyloidosis secondary to rheumatoid arthritis. Arthritis Rheum (2001) 1.08
Cyclopentenone prostaglandins as potential inducers of phase II detoxification enzymes. 15-deoxy-delta(12,14)-prostaglandin j2-induced expression of glutathione S-transferases. J Biol Chem (2000) 1.08
Determination of probability distribution of diplotype configuration (diplotype distribution) for each subject from genotypic data using the EM algorithm. Ann Hum Genet (2002) 1.08
The time-course of preparatory spinal and cortico-spinal inhibition: an H-reflex and transcranial magnetic stimulation study in man. Exp Brain Res (1999) 1.08
The role of neutrophils and inflammation in gastric mucosal injury. Free Radic Res (2000) 1.07
The relationship between serum IgG levels to subgingival gram-negative bacteria and degree of periodontal destruction. J Dent Res (1985) 1.07
Assessment of the gas exchange function of the middle ear using nitrous oxide. A preliminary study. Acta Otolaryngol (1994) 1.07
Inhibition of neuronal nitric-oxide synthase by calcium/ calmodulin-dependent protein kinase IIalpha through Ser847 phosphorylation in NG108-15 neuronal cells. J Biol Chem (2000) 1.06
Alcohol intake and the risk of cardiovascular disease in middle-aged Japanese men. Stroke (1995) 1.06
Cortical processing mechanism for vocalization with auditory verbal feedback. Neuroreport (1997) 1.05
Effect of passive immunization against inhibin on FSH secretion, folliculogenesis and ovulation rate during the follicular phase of the estrous cycle in mares. Theriogenology (1998) 1.05
Successful operative treatment for acute triple-barreled aortic dissection in a patient with Marfan's syndrome: report of a case. Surg Today (1998) 1.05
Rifampicin inhibits the toxicity of pre-aggregated amyloid peptides by binding to peptide fibrils and preventing amyloid-cell interaction. Biochem J (1997) 1.04
Comparison of capsular types of Staphylococcus aureus strains. Infect Immun (1972) 1.04
Involvement of free radicals and oxidative stress in NAFLD/NASH. Free Radic Res (2013) 1.04
cAMP activates the IL-5 promoter synergistically with phorbol ester through the signaling pathway involving protein kinase A in mouse thymoma line EL-4. J Immunol (1993) 1.04
Expression of costimulatory molecules B7-1 and B7-2 by macrophages along invasive margin of colon cancer: a possible antitumor immunity? Lab Invest (1997) 1.03
High-density lipoprotein cholesterol and premature coronary heart disease in urban Japanese men. Circulation (1994) 1.03
Alcohol intake and premature coronary heart disease in urban Japanese men. Am J Epidemiol (1998) 1.03
Activation of lymphokine genes in T cells: role of cis-acting DNA elements that respond to T cell activation signals. Pharmacol Ther (1992) 1.02
A simple method to measure anti-glycolipid antibody by using complement-mediated immune lysis of fluorescent dye-trapped liposomes. J Immunol Methods (1981) 1.02
Evolution of sequence recognition by restriction-modification enzymes: selective pressure for specificity decrease. Mol Biol Evol (2000) 1.02
Levels of IL-12 in the sera of patients with systemic lupus erythematosus (SLE)--relation to Th1- and Th2-derived cytokines. Clin Exp Immunol (1999) 1.02
Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases. Int J Hematol (1998) 1.02
The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study. Osteoarthritis Cartilage (2013) 1.01
Protective efficacy of active and passive immunizations against experimental infection with Bacteroides gingivalis in ligated hamsters. J Dent Res (1988) 1.01