Biogenesis and characterization of histone messenger RNA in HeLa cells.

Isolation and characterization of adenovirus messenger ribonucleic acid in productive infection. J Virol (1972) 3.83

The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro. Mol Cell Biol (1989) 3.69

mRNA poly(A) tail, a 3' enhancer of translational initiation. Mol Cell Biol (1990) 3.58

A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs. Proc Natl Acad Sci U S A (1973) 3.38

Regulation of histone mRNA production and stability in serum-stimulated mouse 3T6 fibroblasts. Mol Cell Biol (1983) 3.13

RNAs of simian virus 40 in productively infected monkey cells: kinetics of formation and decay in enucleate cells. Proc Natl Acad Sci U S A (1975) 2.77

Replication of picornaviruses. I. Evidence from in vitro RNA synthesis that poly(A) of the poliovirus genome is genetically coded. J Virol (1975) 2.42

Ultraviolet light-induced crosslinking of mRNA to proteins. Nucleic Acids Res (1979) 2.38

Histone mRNA degradation in vivo: the first detectable step occurs at or near the 3' terminus. Mol Cell Biol (1986) 2.07

Chinese hamster polyadenylated messenger ribonucleic acid: relationship to non-polyadenylated sequences and relative conservation during messenger ribonucleic acid processing. Mol Cell Biol (1981) 2.00

Large heterogeneous nuclear ribonucleic acid has three times as many 5' caps as polyadenylic acid segments, and most caps do not enter polyribosomes. Mol Cell Biol (1981) 1.97

Newly formed mRNA lacking polyadenylic acid enters the cytoplasm and the polyribosomes but has a shorter half-life in the absence of polyadenylic acid. Mol Cell Biol (1982) 1.79

Direct association of messenger RNA with microsomal membranes in human diploid fibroblasts. J Cell Biol (1975) 1.57

Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells. Mol Cell Biol (1983) 1.54

Nuclear ribonucleoprotein complexes containing polyadenylate from mouse ascites cells. Proc Natl Acad Sci U S A (1974) 1.46

Intracellular distribution and sedimentation properties of virus-specific RNA in two clones of BHK cells transformed by polyoma virus. J Virol (1976) 1.44

Characterization of the mRNA's for the polyoma virus capsid proteins VP1, VP2, and VP3. J Virol (1978) 1.43

Translational properties of rabbit globin mRNA after specific removal of poly(A) with ribonuclease H. Proc Natl Acad Sci U S A (1974) 1.41

Possible relationship of poly(A) shortening to mRNA turnover. Proc Natl Acad Sci U S A (1975) 1.36

Production of viral mRNA in adenovirus- transformed cells by the post- transcriptional processing of heterogeneous nuclear RNA containing viral and cell sequences. J Virol (1973) 1.35

Construction of chimeric plasmids containing histone H5 cDNA from hen erythrocyte. DNA sequence of a fragment derived from the 5' region of H5 mRNA. Nucleic Acids Res (1982) 1.33

Nuclear RNA-protein interactions and messenger RNA processing. J Cell Biol (1983) 1.33

Kinetics and efficiency of polyadenylation of late polyomavirus nuclear RNA: generation of oligomeric polyadenylated RNAs and their processing into mRNA. Mol Cell Biol (1984) 1.32

Control of translation in cultured cells: continued synthesis and accumulation of messenger RNA in nondividing cultures. Proc Natl Acad Sci U S A (1974) 1.32

Cytoplasmic adenylylation and processing of maternal RNA. Proc Natl Acad Sci U S A (1973) 1.26

Enzymatic synthesis of DNA complementary to purified 14S messenger RNA of immunoglobulin light chain. Proc Natl Acad Sci U S A (1973) 1.24

Autogenous regulation of histone mRNA decay by histone proteins in a cell-free system. Mol Cell Biol (1987) 1.21

Purification of a family of specific messenger ribonucleic acids from moth follicular cells. Proc Natl Acad Sci U S A (1973) 1.21

Different 3'-end processing produces two independently regulated mRNAs from a single H1 histone gene. Proc Natl Acad Sci U S A (1989) 1.14

Interaction of poly(A) and mRNA with eukaryotic initiator met-tRNA-f binding factor: identification of this activity on reticulocyte ribonucleic acid protein particles. Proc Natl Acad Sci U S A (1975) 1.09

Preparation of a "functional library" of African green monkey DNA fragments which substitute for the processing/polyadenylation signal in the herpes simplex virus type 1 thymidine kinase gene. Mol Cell Biol (1983) 1.07

Isolation and translation of plant messenger RNA. Plant Physiol (1975) 1.06

Differential stability of host mRNAs in Friend erythroleukemia cells infected with herpes simplex virus type 1. J Virol (1985) 1.05

Characterization of mRNA-protein complexes from mammalian cells. Nucleic Acids Res (1977) 1.04

Kinetics of steroid induction and deinduction of tyrosine aminotransferase synthesis in cultured hepatoma cells. Proc Natl Acad Sci U S A (1975) 1.03

Isolation of a genomal clone containing chicken histone genes. Nucleic Acids Res (1979) 1.01

Temporal relationships of chromatin protein synthesis, DNA synthesis, and assembly of deoxyribonucleoprotein. Proc Natl Acad Sci U S A (1976) 1.01

Translation of nonpolyadenylylated messenger RNA of sea urchin embryos. Proc Natl Acad Sci U S A (1976) 0.99

Specific changes in the messenger ribonucleic acid content of the rat ventral prostate gland after androgenic stimulation. Evidence from the synthesis of aldolase messenger ribonucleic acid. Biochem J (1974) 0.98

A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development. BMC Genomics (2013) 0.98

Use of molecular hybridization to purify and analyze albumin messenger RNA from rat liver. Proc Natl Acad Sci U S A (1977) 0.97

On the localization and transport of specific adenoviral mRNA-sequences in the late infected HeLa cell. Nucleic Acids Res (1982) 0.96

Inhibition of ribonucleic acid efflux from isolated SV40-3T3 cell nuclei by 3'-deoxyadenosine (cordycepin). Biochem J (1979) 0.89

Could poly(A) align the splicing sites of messenger RNA precursors? Proc Natl Acad Sci U S A (1980) 0.88

Lack of poly(A) sequence in half of the messenger RNA coding for ewe alpha S casein. Nucleic Acids Res (1974) 0.87

Translational activity of messenger ribonucleic acid isolated from unstimulated and phytohaemagglutinin-activated lymphocytes. Biochem J (1979) 0.85

Loss of the histone pre-mRNA processing factor stem-loop binding protein in Drosophila causes genomic instability and impaired cellular proliferation. PLoS One (2009) 0.84

Purification of histone messenger ribonucleoprotein particles from HeLa cell S-phase polysomes. Characterization of associated proteins. Nucleic Acids Res (1979) 0.83

Polyadenylylation and transcription following fertilization. Proc Natl Acad Sci U S A (1974) 0.82

A major species of mammalian messenger RNA lacking a polyadenylate segment. Proc Natl Acad Sci U S A (1976) 0.80

Calf lens crystallin messenger RNA's contain polynucleotide sequences rich in adenylic acid. Nucleic Acids Res (1974) 0.79

Synthesis of complementary RNA containing polyadenylic acid by Sendai virions in vitro. J Virol (1976) 0.78

Metabolic heterogeneity of nuclear poly (A)-containing RNA in mouse liver. Nucleic Acids Res (1977) 0.78

Purification of cDNA complementary to sea urchin histone mRNA. Nucleic Acids Res (1977) 0.77

Poly(adenylic acid) in small amounts, free or covalently linked to substrate, protects RNA from hydrolysis by ribonuclease. Biochem J (1981) 0.77

Modulation of poly(A)(+)mRNA-metabolizing and transporting systems under special consideration of microtubule protein and actin. Mol Cell Biochem (1983) 0.76

The 5' terminal capping of heterogeneous nuclear RNA at different embryonic stages of the sea urchin. Nucleic Acids Res (1979) 0.75

E.B. Wilson Lecture, 1998. Eukaryotic RNAs: once more from the beginning. Mol Biol Cell (1999) 0.75

In vitro translation of oogenetic messenger RNA of sea urchin eggs and picornavirus RNA with a cell-free system from sarcoma 180. Proc Natl Acad Sci U S A (1973) 0.75

Structure and expression of the guinea pig preproenkephalin gene: site-specific cleavage in the 3' untranslated region yields truncated mRNA transcripts in specific brain regions. Mol Cell Biol (1995) 0.75

Stat3 as an oncogene. Cell (1999) 17.39

Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol (2002) 15.33

POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNA. Proc Natl Acad Sci U S A (1963) 12.17

Evidence for virus-specific noncapsid proteins in poliovirus-infected HeLa cells. Proc Natl Acad Sci U S A (1965) 11.84

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science (1994) 11.33

An adenylic acid-rich sequence in messenger RNA of HeLa cells and its possible relationship to reiterated sites in DNA. Proc Natl Acad Sci U S A (1971) 11.01

Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA. Science (1971) 10.54

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell (1995) 10.16

Mechanisms for the incorporation of proteins in membranes and organelles. J Cell Biol (1982) 9.67

Variety in the level of gene control in eukaryotic cells. Nature (1982) 9.61

Transcriptional control in the production of liver-specific mRNAs. Cell (1981) 9.35

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem (1995) 8.52

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science (1993) 6.44

The role of STATs in transcriptional control and their impact on cellular function. Oncogene (2000) 6.42

Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicing. Cell (1978) 6.36

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev (1990) 6.33

Ribonucleic acids from animal cells. Bacteriol Rev (1968) 6.13

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science (1992) 6.09

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev (1988) 6.08

Aspects of the synthesis of poliovirus RNA and the formation of virus particles. Virology (1966) 5.85

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell (1994) 5.79

The primary transcription unit of the mouse beta-major globin gene. Cell (1981) 5.75

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science (1992) 5.71

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. Proc Natl Acad Sci U S A (1992) 5.50

Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro. Genes Dev (1989) 5.09

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science (1995) 4.90

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet (1996) 4.84

Transcriptional induction of two genes in human cells by beta interferon. Proc Natl Acad Sci U S A (1984) 4.84

Rapidly labeled HeLa cell nuclear RNA. I. Identification by zone sedimentation of a heterogeneous fraction separate from ribosomal precursor RNA. J Mol Biol (1966) 4.83

The initiation sites for RNA transcription in Ad2 DNA. Cell (1977) 4.76

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science (1993) 4.65

Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci U S A (1987) 4.61

Identification of the membrane protein and "core" protein of Sindbis virus. Proc Natl Acad Sci U S A (1968) 4.52

Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication. Proc Natl Acad Sci U S A (1971) 4.48

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes. Mol Cell Biol (1989) 4.47

Characterization of a new low molecular weight RNA in HeLa cell ribosomes. J Mol Biol (1968) 4.44

Sindbis virus infection of chick and hamster cells: synthesis of virus-specific proteins. Virology (1969) 4.38

Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways. EMBO J (1993) 4.35

Construction of mutant and chimeric genes using the polymerase chain reaction. Nucleic Acids Res (1989) 4.19

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: mapping by effects of ultraviolet irradiation. Cell (1977) 4.13

ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains. Proc Natl Acad Sci U S A (1990) 4.11

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev (1995) 4.11

Stat3 activation is required for cellular transformation by v-src. Mol Cell Biol (1998) 4.09

A transcriptional hierarchy involved in mammalian cell-type specification. Nature (1992) 4.08

Hydrolysis of GTP on rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes. Proc Natl Acad Sci U S A (1998) 4.03

Biogenesis of mRNA: genetic regulation in mammalian cells. Science (1973) 4.01

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev (1991) 4.01

Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells. J Cell Biol (1993) 4.00

Evidence that all messenger RNA molecules (except histone messenger RNA) contain Poly (A) sequences and that the Poly(A) has a nuclear function. J Mol Biol (1972) 3.93

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins. Mol Cell Biol (1992) 3.90

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell (1998) 3.79

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev (1994) 3.76

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. Proc Natl Acad Sci U S A (1992) 3.74

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature (1993) 3.73

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell (1994) 3.71

Production of mRNA in Chinese hamster cells: relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences. Cell (1979) 3.67

Transcriptional induction by interferon. New protein(s) determine the extent and length of the induction. J Biol Chem (1986) 3.63

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc Natl Acad Sci U S A (1996) 3.62

HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev (1990) 3.50

Structural difference between the 5' termini of viral and cellular mRNA in poliovirus-infected cells: possible basis for the inhibition of host protein synthesis. J Virol (1976) 3.46

The decrease in size and synthetic activity of poliovirus polysomes late in the infectious cycle. Virology (1967) 3.41

Competition hybridization by "pre-saturation" of HeLa cell DNA. J Mol Biol (1969) 3.40

Implications of RNA-RNA splicing in evolution of eukaryotic cells. Science (1978) 3.39

The turnover of nuclear DNA-like RNA in HeLa cells. J Cell Biol (1968) 3.39

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene. Proc Natl Acad Sci U S A (1987) 3.38

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med (1995) 3.37

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: mapping of nascent RNA molecules labeled in isolated nuclei. Cell (1977) 3.32

Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either. Mol Cell Biol (1990) 3.31

Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor. EMBO J (1991) 3.28

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc Natl Acad Sci U S A (1996) 3.26

Effect of adenovirus on metabolism of specific host mRNAs: transport control and specific translational discrimination. Mol Cell Biol (1983) 3.25

Rapidly labeled HeLa cell nuclear RNA. II. Base composition and cellular localization of a heterogeneous RNA fraction. J Mol Biol (1966) 3.22

Double-stranded regions in heterogeneous nuclear RNA from Hela cells. Proc Natl Acad Sci U S A (1972) 3.21

Polyadenylic acid segment in mRNA becomes shorter with age. Nat New Biol (1973) 3.09

Early Ad-2 transcription units: only promoter-proximal RNA continues to be made in the presence of DRB. Virology (1979) 3.06

SV40-specific RNA in the nucleus and polyribosomes of transformed cells. Proc Natl Acad Sci U S A (1970) 3.05

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Mol Cell Biol (1985) 3.04

The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci. DNA (1989) 3.03

Methylated, blocked 5 termini in HeLa cell mRNA. Proc Natl Acad Sci U S A (1975) 3.02

Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol Cell Biol (1983) 3.01

The P450 gene superfamily: recommended nomenclature. DNA (1987) 2.95

Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region. Proc Natl Acad Sci U S A (1986) 2.92

Regulation of the primary expression of the early adenovirus transcription units. J Virol (1979) 2.92

Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity. Proc Natl Acad Sci U S A (1995) 2.92

Identification of a Stat gene that functions in Drosophila development. Cell (1996) 2.90

Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc Natl Acad Sci U S A (1994) 2.85

Stat3 and Stat4: members of the family of signal transducers and activators of transcription. Proc Natl Acad Sci U S A (1994) 2.81

Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3. EMBO J (1990) 2.75

Globin RNA transcription: a possible termination site and demonstration of transcriptional control correlated with altered chromatin structure. Cell (1982) 2.72

Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol Cell Biol (1992) 2.72

Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons. Mol Cell Biol (1991) 2.71

Processing of adenovirus specific nuclear RNA during virus replication. Virology (1972) 2.71

A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes. Proc Natl Acad Sci U S A (1988) 2.71

The effects of methionine deprivation on ribosome synthesis in HeLa cells. Proc Natl Acad Sci U S A (1967) 2.66

Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA. J Mol Biol (1973) 2.61

The inhibition by DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells. Cell (1976) 2.60

Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes. Proc Natl Acad Sci U S A (1988) 2.58