Published in Proc Natl Acad Sci U S A on January 01, 1971
Cytological mapping of human X-linked genes by use of somatic cell hybrids involving an X-autosome translocation (mouse-hamster-human X-linked markers). Proc Natl Acad Sci U S A (1972) 1.42
Genetics of human-mouse somatic cell hybrids: linkage of human genes for lactate dehydrogenase-A and esterase-A 4 . Proc Natl Acad Sci U S A (1972) 1.38
The scattered distribution of actin genes in the mouse and human genomes. EMBO J (1982) 1.26
X-linkage of human phosphoglycerate kinase confirmed in man-mouse and man-Chinese hamster somatic cell hybrids. Am J Hum Genet (1971) 1.13
Identification of human RNA transcripts among heterogeneous nuclear RNA from man-mouse somatic cell hybrids. Proc Natl Acad Sci U S A (1975) 1.09
The human genes for hemophilia A and hemophilia B flank the X chromosome fragile site at Xq27.3. EMBO J (1985) 1.09
Restoration of hypoxanthine phosphoribosyl transferase activity in mouse 1R cells after fusion with chick-embryo fibroblasts. Proc Natl Acad Sci U S A (1973) 1.04
Expression of two X-linked genes in human hair follicles of double heterozygotes. Proc Natl Acad Sci U S A (1971) 1.03
Disparate enzyme activity in erythocytes and leukocytes. A variant of hypoxanthine phosphoribosyl-transferase deficiency with an unstable enzyme. J Clin Invest (1973) 0.99
Entrapment of metaphase chromosomes into phospholipid vesicles (lipochromosomes): carrier potential in gene transfer. Proc Natl Acad Sci U S A (1978) 0.94
Linkage relationships of X-linked enzymes glucose-6-phosphate dehydrogenase and hypoxanthine guanine phosphoribosyltransferase: recombination in female offspring of compound heterozygotes. Am J Hum Genet (1974) 0.93
Isolation and subregional mapping of an arbitrary cloned probe detecting a common RFLP on human chromosome 2. Am J Hum Genet (1985) 0.77
Chromosomes of older humans are more prone to aminopterine-induced breakage. Proc Natl Acad Sci U S A (1989) 0.76
Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis. Science (1967) 7.75
HYBRID CELLS DERIVED FROM MOUSE AND MAN: ARTIFICIAL HETEROKARYONS OF MAMMALIAN CELLS FROM DIFFERENT SPECIES. Nature (1965) 6.50
The use of drug-resistant markers to study the hybridization of mouse fibroblasts. Exp Cell Res (1966) 5.19
Genetics of human cess line. IV. DNA-mediated heritable transformation of a biochemical trait. Proc Natl Acad Sci U S A (1962) 4.96
DEMONSTRATION OF TWO POPULATIONS OF CELLS IN THE HUMAN FEMALE HETEROZYGOUS FOR GLUCOSE-6-PHOSPHATE DEHYDROGENASE VARIANTS. Proc Natl Acad Sci U S A (1963) 4.89
Human-mouse hybrid cell lines containing partial complements of human chromosomes and functioning human genes. Proc Natl Acad Sci U S A (1967) 4.83
THREE DEGREES OF GUANYLIC ACID--INOSINIC ACID PYROPHOSPHORYLASE DEFICIENCY IN MOUSE FIBROBLASTS. Nature (1964) 4.67
Hemizygous expression of glucose-6-phosphate dehydrogenase in erythrocytes of heterozygotes for the Lesch-Nyhan syndrome. Proc Natl Acad Sci U S A (1970) 3.05
Genetic analysis with human--mouse somatic cell hybrids. Nature (1969) 2.82
X-linked hypoxanthine-guanine phosphoribosyl transferase deficiency: heterozygote has two clonal populations. Science (1968) 2.69
Erythrocyte glucose-6-phosphate dehydrogenase deficiency: evidence of differences between Negroes and Caucasians with respect to this genetically determined trait. J Clin Invest (1959) 2.52
Human-mouse somatic cell hybrids with single human chromosome (group E): link with thymidine kinase activity. Science (1968) 1.96
Properties and uses of human-mouse hybrid cell lines. Nature (1968) 1.82
Population genetic studies in the Congo. I. Glucose-6-phosphate dehydrogenase deficiency, hemoglobin S, and malaria. Am J Hum Genet (1966) 1.72
Synthesis of an enzyme determined by an erythrocyte nucleus in a hybrid cell. J Cell Sci (1969) 1.44
The nature of thymidine kinase in the human-mouse hybrid cell. Biochem Genet (1969) 1.05
Chromosomal damage of human cells induced by Sendai virus. Ann Med Exp Biol Fenn (1965) 1.01
Isolation and properties of hybrids between somatic mouse and Chinese hamster cells. Genetics (1967) 0.82
Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants. Proc Natl Acad Sci U S A (1977) 13.87
Site-specific integration by adeno-associated virus. Proc Natl Acad Sci U S A (1990) 7.06
The dilemma of MDR-TB in the global era. Int J Tuberc Lung Dis (1998) 5.77
A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell (1985) 5.63
Visualization of focal sites of transcription within human nuclei. EMBO J (1993) 5.06
Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B. J Cell Biol (2001) 4.96
Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A (1999) 4.42
Coupled transcription and translation within nuclei of mammalian cells. Science (2001) 3.62
Molecular genetic tests as a guide to surgical management of familial adenomatous polyposis. Lancet (1996) 3.41
Suppression of malignancy by cell fusion. Nature (1969) 3.41
Visualization of replication factories attached to nucleoskeleton. Cell (1993) 3.36
Timely diagnosis of MDR-TB under program conditions: is rapid drug susceptibility testing sufficient? Int J Tuberc Lung Dis (2006) 3.34
A general method for preparing chromatin containing intact DNA. EMBO J (1985) 3.22
The locus of enterocyte effacement (LEE)-encoded regulator controls expression of both LEE- and non-LEE-encoded virulence factors in enteropathogenic and enterohemorrhagic Escherichia coli. Infect Immun (2000) 3.20
Active RNA polymerases are localized within discrete transcription "factories' in human nuclei. J Cell Sci (1996) 3.16
Enzyme electrophoresis on cellulose acetate gel: zymogram patterns in mgh-mouse and man--Chinese hamster somatic cell hybrids. Arch Biochem Biophys (1971) 3.15
Identification of the mouse karyotype by quinacrine fluorescence, and tentative assignment of seven linkage groups. Proc Natl Acad Sci U S A (1971) 3.10
Transcription occurs at a nucleoskeleton. EMBO J (1985) 3.07
5-Methylcytosine localised in mammalian constitutive heterochromatin. Nature (1974) 3.06
A human Y-linked DNA polymorphism and its potential for estimating genetic and evolutionary distance. Science (1985) 2.88
Supercoils in human DNA. J Cell Sci (1975) 2.85
International system for human gene nomenclature (1979) ISGN (1979). Cytogenet Cell Genet (1979) 2.58
A general method for preparing intact nuclear DNA. EMBO J (1984) 2.55
Giant Rashba-type spin splitting in bulk BiTeI. Nat Mater (2011) 2.49
RNA is synthesized at the nuclear cage. Nature (1981) 2.36
The inhomogeneous structure of water at ambient conditions. Proc Natl Acad Sci U S A (2009) 2.31
Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei. Mol Biol Cell (1998) 2.30
Population genetics of haemoglobin variants, thalassaemia and glucose-6-phosphate dehydrogenase deficiency, with particular reference to the malaria hypothesis. Bull World Health Organ (1966) 2.30
Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III. EMBO J (1999) 2.28
Influenza virus RNA is synthesized at fixed sites in the nucleus. Nature (1982) 2.18
Characterization of nuclear structures containing superhelical DNA. J Cell Sci (1976) 2.16
A gentle method for preparing cyto- and nucleo-skeletons and associated chromatin. J Cell Sci (1988) 2.12
The 13q-deletion syndrome. Am J Hum Genet (1969) 2.06
DNA is replicated at the nuclear cage. J Cell Sci (1980) 2.06
Replication occurs at a nucleoskeleton. EMBO J (1986) 2.05
Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer. Cancer Res (1994) 1.99
Erythroid cell differentiation: murine erythroleukemia cell variant with unique pattern of induction by polar compounds. Proc Natl Acad Sci U S A (1976) 1.99
Two genetic markers closely linked to adult polycystic kidney disease on chromosome 16. Br Med J (Clin Res Ed) (1986) 1.93
Epithelial cell polarity affects susceptibility to Pseudomonas aeruginosa invasion and cytotoxicity. Infect Immun (1997) 1.90
Loss of human genetic markers in man--Chinese hamster somatic cell hybrids. Nat New Biol (1971) 1.88
Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22. Cytogenet Cell Genet (1980) 1.88
Simultaneous identification of chromatid replication and of human chromosomes in metaphases of man-mouse somatic cell hybrids. (With 1 color plate). Cytogenet Cell Genet (1977) 1.88
Active viral genes in transformed cells lie close to the nuclear cage. EMBO J (1982) 1.86
Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells. J Cell Sci (1995) 1.85
Failure to detect linkage between Xg and other X-borne loci in Sardinians. Ann Hum Genet (1966) 1.82
Direct imaging of DNA in living cells reveals the dynamics of chromosome formation. J Cell Biol (1999) 1.81
Studies on African Pygmies. I. A pilot investigation of Babinga Pygmies in the Central African Republic (with an analysis of genetic distances). Am J Hum Genet (1969) 1.81
Quantitation of RNA polymerase II and its transcription factors in an HeLa cell: little soluble holoenzyme but significant amounts of polymerases attached to the nuclear substructure. Mol Cell Biol (1999) 1.79
Expression of human and suppression of mouse nucleolus organizer activity in mouse-human somatic cell hybrids. Proc Natl Acad Sci U S A (1976) 1.77
Conformational constraints in nuclear DNA. J Cell Sci (1976) 1.77
Variability of red cell phenotypes between and within individuals in an unbiased sample of 77 heterozygotes for G6PD deficiency in Sardinia. Am J Hum Genet (1976) 1.77
Happy mapping: linkage mapping using a physical analogue of meiosis. Nucleic Acids Res (1993) 1.77
Human alpha-globin maps to pter-p13.3 in chromosome 16 distal to PGP. Hum Genet (1987) 1.76
Enzyme electrophoresis on cellulose acetate gel. II. Zymogram patterns in man-Chinese hamster somatic cell hybrids. Humangenetik (1974) 1.76
The size of chromatin loops in HeLa cells. EMBO J (1990) 1.75
Visualization of a filamentous nucleoskeleton with a 23 nm axial repeat. EMBO J (1988) 1.70
Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage. Nucleic Acids Res (1980) 1.70
Comparison of tilmicosin with long-acting oxytetracycline for treatment of respiratory tract disease in calves. J Am Vet Med Assoc (1996) 1.70
Global regulatory mutations in csrA and rpoS cause severe central carbon stress in Escherichia coli in the presence of acetate. J Bacteriol (2000) 1.67
Germline mutations in the 3' part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli. Hum Genet (1996) 1.67
Psychiatric issues in the management of patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis (2004) 1.65
Acetate metabolism in a pta mutant of Escherichia coli W3110: importance of maintaining acetyl coenzyme A flux for growth and survival. J Bacteriol (1999) 1.62
Plant thioredoxin h: an animal-like thioredoxin occurring in multiple cell compartments. Arch Biochem Biophys (1991) 1.62
Abnormally high expression of proteasomes in human leukemic cells. Proc Natl Acad Sci U S A (1990) 1.62
Alternative DNA replication patterns associated with long arm length of chromosomes 4 and 5 in the cri du chat syndrome. Cytogenetics (1966) 1.62
Suppression of human nucleolus organizer activity in mouse-human somatic hybrid cells. Exp Cell Res (1976) 1.62
Identification of translocation chromosomes by quinacrine fluorescence. Am J Dis Child (1972) 1.62
Suppression of production of mouse 28S ribosomal RNA in mouse-human hybrids segregating mouse chromosomes. Proc Natl Acad Sci U S A (1977) 1.60
X-linkage of steroid sulphatase in the mouse is evidence for a functional Y-linked allele. Nature (1985) 1.60
Clinical appearances, healing patterns, risk factors, and outcomes of horses with fungal keratitis: 53 cases (1978-1996) J Am Vet Med Assoc (1998) 1.59
Spectrofluorometric measurement of the binding of ethidium to superhelical DNA from cell nuclei. Eur J Biochem (1978) 1.58
Expression of H-Y antigen in human males with two Y chromosomes. N Engl J Med (1975) 1.56
Cytological detection of the c-25H deletion involving the albino (c) locus on chromosome 7 in the mouse. Genetics (1974) 1.55
A human autosomal phosphoglycerate kinase locus maps near the HLA cluster. Proc Natl Acad Sci U S A (1984) 1.55
Quinacrine fluorescent karyotypes of human diploid and heteroploid cell lines. Cytogenetics (1971) 1.54
Translocation heterozygosis: a cause of five cases of the cri du chat syndrome and two cases with a duplication of chromosome number five in three families. Am J Hum Genet (1967) 1.53
Replication factories and nuclear bodies: the ultrastructural characterization of replication sites during the cell cycle. J Cell Sci (1994) 1.52
The quinacrine fluorescence karyotype of Mus musculus and demonstration of strain differences in secondary constrictions. Cytogenetics (1971) 1.52
Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes. Chem Biol (1998) 1.51
A cost-effectiveness analysis of colorectal screening of hereditary nonpolyposis colorectal carcinoma gene carriers. Cancer (1998) 1.49
Evidence for intergenic complementation in hybrid cells derived from two human diploid strains each carrying an X-linked mutation. Proc Natl Acad Sci U S A (1969) 1.48
Efficacy of interferon alfa therapy in chronic hepatitis C patients depends primarily on hepatitis C virus RNA level. Hepatology (1995) 1.47
Preferential derivation of abnormal human G-group-like chromosomes from chromosome 15. Hum Genet (1977) 1.46
Synthesis of an enzyme determined by an erythrocyte nucleus in a hybrid cell. J Cell Sci (1969) 1.44
The nucleoskeleton: artefact, passive framework or active site? J Cell Sci (1988) 1.44
Amplified ribosomal RNA genes in a rat hepatoma cell line are enriched in 5-methylcytosine. Proc Natl Acad Sci U S A (1981) 1.44
A cell-cycle-dependent DNA polymerase activity that replicates intact DNA in chromatin. J Mol Biol (1986) 1.44
Correction of a genetic defect in a mammalian cell. Nat New Biol (1971) 1.44
Symptom outcome after functional endoscopic sinus surgery in patients with cystic fibrosis: a prospective study. Otolaryngol Head Neck Surg (1995) 1.43
X-linked ichthyosis without STS deficiency: clinical, genetical, and molecular studies. Am J Med Genet (1995) 1.42
Cytological mapping of human X-linked genes by use of somatic cell hybrids involving an X-autosome translocation (mouse-hamster-human X-linked markers). Proc Natl Acad Sci U S A (1972) 1.42
Replication and transcription depend on attachment of DNA to the nuclear cage. J Cell Sci Suppl (1984) 1.39
APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis. Hum Genet (1995) 1.39
Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein. J Cell Sci (2000) 1.38
Human thymidine kinase gene locus: assignment to chromosome 17 in a hybrid of man and mouse cells. Science (1971) 1.37
Report of the committee on the genetic constitution of the x and y chromosomes. Oslo Conference (1981): Sixth International Workshop on Human Gene Mapping. Cytogenet Cell Genet (1982) 1.37