Published in Am J Ophthalmol on March 01, 1967
Evaluation of darkfield and immunofluorescent techniques for demonstrating Treponema pallidum in fluids with small numbers of organisms. Br J Vener Dis (1969) 2.04
Experimental rabbit syphilis. Br J Vener Dis (1971) 1.55
Recovery of spirochagetes in the monkey by passive transfer from human late sero-negative syphilis. Br J Vener Dis (1968) 1.17
Fluorescent antibody methods in the detection and control of venereal diseases. A bibliographical review of the literature. Br J Vener Dis (1969) 0.95
Immunofluorescent staining for the detection of Treponema pallidum in early syphilitic lesions. Br J Vener Dis (1971) 0.89
Late ocular syphilis: transfer of infection from man to experimental animals. Trans Am Ophthalmol Soc (1969) 0.75
Comparison of direct and indirect fluorescent antibody methods for staining Treponema pallidum. Br J Vener Dis (1971) 0.75
The mass and oxygen capacity of the blood in man. J Physiol (1900) 10.55
A hot spot of binding energy in a hormone-receptor interface. Science (1995) 10.41
High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. Science (1989) 8.73
Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc Natl Acad Sci U S A (1999) 5.66
Crystal structure of core streptavidin determined from multiwavelength anomalous diffraction of synchrotron radiation. Proc Natl Acad Sci U S A (1989) 5.57
The Absorption of Oxygen by the Lungs. J Physiol (1897) 4.50
Convergent solutions to binding at a protein-protein interface. Science (2000) 4.47
A prospective study of advance directives for life-sustaining care. N Engl J Med (1991) 3.72
Cloning, sequencing, and secretion of Bacillus amyloliquefaciens subtilisin in Bacillus subtilis. Nucleic Acids Res (1983) 3.70
Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. J Immunol (1997) 3.56
The Oxygen Tension of Arterial Blood. J Physiol (1896) 3.40
oskar mRNA is localized to the posterior pole of the Drosophila oocyte. Cell (1991) 3.39
The course of patients after variceal hemorrhage. Gastroenterology (1981) 3.33
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation. Nature (1995) 3.30
The pathological effects due to increase of oxygen tension in the air breathed. J Physiol (1899) 3.28
Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4. J Virol (1987) 3.24
Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule. Science (1991) 3.24
Hepatitis B infection in physicians. Results of a nationwide seroepidemiologic survey. JAMA (1978) 3.24
Dissecting the catalytic triad of a serine protease. Nature (1988) 3.19
In vitro selection of zinc fingers with altered DNA-binding specificity. Biochemistry (1994) 3.18
Comparison of a structural and a functional epitope. J Mol Biol (1993) 3.12
Systematic mutational analyses of protein-protein interfaces. Methods Enzymol (1991) 2.95
Structure of myohemerythrin in the azidomet state at 1.7/1.3 A resolution. J Mol Biol (1987) 2.79
Phage display for selection of novel binding peptides. Methods Enzymol (2000) 2.78
Variceal hemorrhage: a critical evaluation of survival analysis. Gastroenterology (1982) 2.60
Site-directed ligand discovery. Proc Natl Acad Sci U S A (2000) 2.58
Immunologic tolerance to renal allografts after bone marrow transplants from the same donors. Ann Intern Med (1991) 2.46
Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. Blood (2000) 2.45
Rational design of potent antagonists to the human growth hormone receptor. Science (1992) 2.45
A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptor. Proc Natl Acad Sci U S A (1991) 2.43
Paracentric inversions in humans: a review of 446 paracentric inversions with presentation of 120 new cases. Am J Med Genet (1995) 2.39
Spirochetes in the aqueous humor in seronegative ocular syphilis. Persistence after penicillin therapy. Arch Ophthalmol (1967) 2.30
Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Cell (1997) 2.24
Motility in Pseudomonas fluorescens with special reference to survival advantage and negative chemotaxis. Life Sci (1968) 2.17
ON A CASE OF SEPTICAEMIA TREATED BY INTRAVENOUS INJECTION OF EUSOL. Br Med J (1915) 2.16
Cassette mutagenesis: an efficient method for generation of multiple mutations at defined sites. Gene (1985) 2.15
Spontaneous regression of primary malignant melanomas with regional metastases. Cancer (1965) 2.15
Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site. Structure (1996) 2.14
Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion. Lancet (1993) 2.12
The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families. Nat Struct Biol (1996) 2.11
A new modification of the Krajian silver stain for Treponema pallidum. Br J Vener Dis (1969) 2.09
Using the Internet for psychological research: personality testing on the World Wide Web. Br J Psychol (1999) 2.06
Gastroduodenal mucosa and dyspeptic symptoms in arthritic patients during chronic nonsteroidal anti-inflammatory drug use. Am J Gastroenterol (1987) 2.05
Structural plasticity in a remodeled protein-protein interface. Science (1997) 2.05
Substrate phage: selection of protease substrates by monovalent phage display. Science (1993) 2.04
Direct phase determination based on anomalous scattering. Methods Enzymol (1985) 2.02
Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis. Science (1989) 2.02
Hereditary aspects of malignant melanoma. JAMA (1967) 1.98
Iatrogenic Campylobacter pylori infection is a cause of epidemic achlorhydria. Am J Gastroenterol (1988) 1.97
Gastric adaptation. Studies in humans during continuous aspirin administration. Gastroenterology (1988) 1.97
A second-generation study of 427 probands with congenital heart defects and their 837 children. J Am Coll Cardiol (1994) 1.97
Hormone phage: an enrichment method for variant proteins with altered binding properties. Proteins (1990) 1.94
Incidence of reactive VDRL tests in the normal rabbit. Br J Vener Dis (1967) 1.94
Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site. Proc Natl Acad Sci U S A (1997) 1.91
T and B lymphocytes and Reed-Sternberg cells in Hodgkin's disease lymph nodes and spleens. Clin Exp Immunol (1976) 1.91
Experimental Observations ON THE ANTISEPTIC ACTION OF HYPOCHLOROUS ACID AND ITS APPLICATION TO WOUND TREATMENT. Br Med J (1915) 1.87
B- and T-lymphocyte markers on transformed lymphocytes from mitogen-stimulated cultures of normal and CLL lymphocytes and on tonsil blasts. Clin Exp Immunol (1974) 1.86
Multiple RNA regulatory elements mediate distinct steps in localization of oskar mRNA. Development (1993) 1.86
The prevalence of homosexual behavior and attraction in the United States, the United Kingdom and France: results of national population-based samples. Arch Sex Behav (1995) 1.86
Optic nerve sheath decompression for relief of chronic monocular choked disc. Am J Ophthalmol (1969) 1.84
Microbiology of the frankfurter process: salmonella and natural aerobic flora. Appl Microbiol (1974) 1.83
Muscle fibre type populations of human leg muscles. Histochem J (1975) 1.83
Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J Mol Biol (1998) 1.79
A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues. Science (1994) 1.79
Characterisation of malignant mediastinal lymphoid neoplasm (Sternberg sarcoma) as thymic in origin. Lancet (1973) 1.78
Aspirin and the stomach. Ann Intern Med (1986) 1.77
RNA regulatory element BLE1 directs the early steps of bicoid mRNA localization. Development (1993) 1.76
Whence pseudotumor cerebri? J Clin Neuroophthalmol (1985) 1.76
Recovery of Treponema pallidum from aqueous humor removed at cataract surgery in man by passive transfer to rabbit testis. Am J Ophthalmol (1968) 1.76
Minimizing a binding domain from protein A. Proc Natl Acad Sci U S A (1996) 1.75
A mutant herpesvirus protein leads to a block in nuclear localization of other viral proteins. Mol Cell Biol (1986) 1.75
Immunological reason for chronic ill health after infectious mononucleosis. Br Med J (Clin Res Ed) (1983) 1.74
Locally critical quantum phase transitions in strongly correlated metals. Nature (2001) 1.74
Occupational stress and health among factory workers. J Health Soc Behav (1979) 1.72
Secretion and autoproteolytic maturation of subtilisin. Proc Natl Acad Sci U S A (1986) 1.72
Studies on negative chemotaxis and the survival value of motility in Pseudomonas fluorescens. J Gen Microbiol (1969) 1.71
Non-tumor causes of the Foster Kennedy syndrome. J Neurosurg (1967) 1.71
Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site. Biochemistry (1997) 1.70
The current status of treponema cuniculi. Review of the literature. Br J Vener Dis (1967) 1.69
Painful ophthalmoplegia. The Tolosa-Hunt syndrome. Am J Ophthalmol (1966) 1.68
In vitro selection from protein and peptide libraries. Trends Biotechnol (1994) 1.68
Enzymes utilizing glutamine as an amide donor. Adv Enzymol Relat Areas Mol Biol (1998) 1.67
Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution. Biochemistry (1991) 1.66
Selecting high-affinity binding proteins by monovalent phage display. Biochemistry (1991) 1.66
Active site trapping of nucleotides by crosslinking two sulfhydryls in myosin subfragment 1. Proc Natl Acad Sci U S A (1979) 1.65
Mechanisms of neurulation: traditional viewpoint and recent advances. Development (1990) 1.64
Crystallographic structure analysis of lamprey hemoglobin from anomalous dispersion of synchrotron radiation. Proteins (1988) 1.64
Zinc mediation of the binding of human growth hormone to the human prolactin receptor. Science (1990) 1.63
Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation. Antimicrob Agents Chemother (1997) 1.60
Designing substrate specificity by protein engineering of electrostatic interactions. Proc Natl Acad Sci U S A (1987) 1.58
Experimental seronegative syphilis. Am J Ophthalmol (1965) 1.56
Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group. N Engl J Med (1995) 1.55
Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor. J Biol Chem (1998) 1.53
In vivo formation and stability of engineered disulfide bonds in subtilisin. J Biol Chem (1986) 1.51
Skin involvement in Hodgkin's disease. Cancer (1980) 1.51
Affinity maturation of human growth hormone by monovalent phage display. J Mol Biol (1993) 1.51
Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin. J Neurosci Res (2008) 1.50
Ischemic optic neuropathy. Am J Ophthalmol (1966) 1.49
Leber's idiopathic stellate neuroretinitis. Arch Ophthalmol (1984) 1.49