Published in Science on May 26, 1967
Revised linkage map of Salmonella typhimurium. Bacteriol Rev (1967) 5.22
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Methionine-mediated repression in Saccharomyces cerevisiae: a pleiotropic regulatory system involving methionyl transfer ribonucleic acid and the product of gene eth2. J Bacteriol (1971) 1.60
Serine biosynthesis and regulation in Haemophilus influenzae. J Bacteriol (1969) 1.17
Control of isoleucine, valine, and leucine biosynthesis. VI. Effect of 5',5',5'-trifluoroleucine on repression in Salmonella typhimurium. J Bacteriol (1969) 1.12
flrB, a regulatory locus controlling branched-chain amino acid biosynthesis in Salmonella typhimurium. J Bacteriol (1974) 0.99
Construction and characterization of Salmonella typhimurium strains that accumulate and excrete alpha- and beta-isopropylmalate. J Bacteriol (1980) 0.88
Nucleotide sequence of the E coli gene coding for dihydrofolate reductase. Nucleic Acids Res (1980) 8.75
A large family of bacterial activator proteins. Proc Natl Acad Sci U S A (1988) 8.19
Compounds which serve as the sole source of carbon or nitrogen for Salmonella typhimurium LT-2. J Bacteriol (1969) 5.99
leu operon of Salmonella typhimurium is controlled by an attenuation mechanism. Proc Natl Acad Sci U S A (1979) 2.91
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Characterization of Lrp, and Escherichia coli regulatory protein that mediates a global response to leucine. J Biol Chem (1991) 2.83
The ilvIH operon of Escherichia coli is positively regulated. J Bacteriol (1990) 2.71
Alternative secondary structures of leader RNAs and the regulation of the trp, phe, his, thr, and leu operons. Proc Natl Acad Sci U S A (1979) 2.71
Molecular structure of ilvIH and its evolutionary relationship to ilvG in Escherichia coli K12. Nucleic Acids Res (1983) 2.39
Mutants of Salmonella typhimurium with an altered leucyl-transfer ribonucleic acid synthetase. J Bacteriol (1971) 2.19
A multisite-mutation map of the leucine operon of Salmonella typhimurium. Genetics (1970) 2.17
Lrp, a global regulatory protein of Escherichia coli, binds co-operatively to multiple sites and activates transcription of ilvIH. J Mol Biol (1993) 2.17
Control of leu operon expression in Escherichia coli by a transcription attenuation mechanism. J Mol Biol (1981) 2.01
Transcriptional regulation of the ilv-leu operon of Bacillus subtilis. J Bacteriol (1992) 1.96
A consensus sequence for binding of Lrp to DNA. J Bacteriol (1995) 1.88
Physical characterization of the ilvHI operon of Escherichia coli K-12. J Bacteriol (1981) 1.85
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The nucleotide sequence of a rat myosin light chain 2 gene. Nucleic Acids Res (1984) 1.81
Leucine-responsive regulatory protein controls the expression of both the pap and fan pili operons in Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.81
Regions of the Bacillus subtilis ilv-leu operon involved in regulation by leucine. J Bacteriol (1993) 1.76
Fluorometric assay of enzymatic reactions involving acetyl Coenzyme A in aldol condensations. Anal Biochem (1969) 1.75
A protein that binds to the regulatory region of the Escherichia coli ilvIH operon. J Bacteriol (1989) 1.75
Lrp, a leucine-responsive protein, regulates branched-chain amino acid transport genes in Escherichia coli. J Bacteriol (1992) 1.74
Lrp, a major regulatory protein in Escherichia coli, bends DNA and can organize the assembly of a higher-order nucleoprotein structure. EMBO J (1993) 1.74
Mutations affecting the ability of Escherichia coli Lrp to bind DNA, activate transcription, or respond to leucine. J Bacteriol (1993) 1.70
Unusual organization of the ilvIH promoter of Escherichia coli. J Bacteriol (1985) 1.68
Effects of nutrition and growth rate on Lrp levels in Escherichia coli. J Bacteriol (1996) 1.67
Characterization of the 3' end of the leucine operon of Salmonella typhimurium. Mol Gen Genet (1985) 1.63
Regulation of the Escherichia coli lrp gene. J Bacteriol (1994) 1.56
Regulation of dihydrofolate reductase synthesis in Escherichia coli. Mol Gen Genet (1979) 1.53
Salmonella locus affecting phosphoenolpyruvate synthase activity identified by a deletion analysis. J Bacteriol (1971) 1.30
The ilvIH operon of Escherichia coli K-12. Identification of the gene products and recognition of the translational start by polypeptide microsequencing. Biochim Biophys Acta (1985) 1.25
IlvHI locus of Salmonella typhimurium. J Bacteriol (1983) 1.21
The nucleotide sequence of leuA from Salmonella typhimurium. Nucleic Acids Res (1990) 1.20
Leucine-regulated self-association of leucine-responsive regulatory protein (Lrp) from Escherichia coli. J Mol Biol (2001) 1.20
Transcription attenuation is the major mechanism by which the leu operon of Salmonella typhimurium is controlled. J Mol Biol (1983) 1.18
Isolation and characterization of lambda pleu bacteriophages. J Bacteriol (1977) 1.16
Amplification and modification of dihydrofolate reductase in Escherichia coli. Nucleotide sequence of fol genes from mutationally altered plasmids. J Biol Chem (1982) 1.14
Transcription initiation sites of the leucine operons of Salmonella typhimurium and Escherichia coli. J Mol Biol (1983) 1.14
Leucyl-transfer ribonucleic acid synthetase from a wild-type and temperature-sensitive mutant of Salmonella typhimurium. J Bacteriol (1972) 1.14
Cloning of an EcoRI-generated fragment of the leucine operon of Salmonella typhimurium. Gene (1980) 1.14
A Salmonella typhimurium locus involved in the regulation of isoleucine, valine and leucine biosynthesis. Genetics (1969) 1.14
High A + T content conserved in DNA sequences upstream of leuABCD in Escherichia coli and Salmonella typhimurium. J Bacteriol (1986) 1.13
Nucleotide sequence of dihydrofolate reductase genes from trimethoprim-resistant mutants of Escherichia coli. Evidence that dihydrofolate reductase interacts with another essential gene product. Mol Gen Genet (1982) 1.12
Distribution of the isopropylmalate pathway to leucine among diverse bacteria. J Bacteriol (1974) 1.08
In vitro transcription from the Escherichia coli ilvIH promoter. J Bacteriol (1992) 1.08
The leucine-responsive regulatory protein (Lrp) from Escherichia coli. Stoichiometry and minimal requirements for binding to DNA. J Biol Chem (1996) 1.07
Transcription termination sites at the distal end of the leu operon of Salmonella typhimurium. J Mol Biol (1987) 1.07
The nucleotide sequence of leuC from Salmonella typhimurium. Nucleic Acids Res (1990) 1.05
Recognition of an Escherichia operator by a Salmonella repressor. J Bacteriol (1971) 1.00
Mutations that convert the four leucine codons of the Salmonella typhimurium leu leader to four threonine codons. J Bacteriol (1985) 1.00
Acetolactate synthase isozyme III from Escherichia coli. Methods Enzymol (1988) 1.00
Relationship between messenger ribonucleic acid and enzyme levels specified by the leucine operon of Escherichia coli K-12. J Bacteriol (1977) 1.00
Organization of Lrp-binding sites upstream of ilvIH in Salmonella typhimurium. Mol Microbiol (1993) 1.00
Promoter mutation causing catabolite repression of the Salmonella typhimurium leucine operon. J Bacteriol (1984) 0.99
flrB, a regulatory locus controlling branched-chain amino acid biosynthesis in Salmonella typhimurium. J Bacteriol (1974) 0.99
Modulation of Lrp action in Escherichia coli by leucine: effects on non-specific binding of Lrp to DNA. J Mol Biol (2001) 0.98
Transcription attenuation in Salmonella typhimurium: the significance of rare leucine codons in the leu leader. Proc Natl Acad Sci U S A (1986) 0.97
Effect of 4-azaleucine upon leucine metabolism in Salmonella typhimurium. J Bacteriol (1971) 0.95
Global versus local regulatory roles for Lrp-related proteins: Haemophilus influenzae as a case study. J Bacteriol (2001) 0.92
Alpha-isopropylmalate synthase from Salmonella typhimurium. Carboxypeptidase digestion studies of parent and feedback-insensitive enzymes. Biochim Biophys Acta (1971) 0.92
The amino acid sequence of Lrp is highly conserved in four enteric microorganisms. J Bacteriol (1995) 0.91
Transcriptional proofreading in Escherichia coli. EMBO J (1989) 0.89
Escherichia coli B/r leuK mutant lacking pseudouridine synthase I activity. J Bacteriol (1986) 0.86
Transcription attenuation-mediated control of leu operon expression: influence of the number of Leu control codons. J Bacteriol (1991) 0.85
Phasic activity of the basolateral amygdala, cingulate gyrus, and hippocampus during REM sleep in the cat. Sleep (1984) 0.84
Permeabilized cell and radiochemical assays for beta-isopropylmalate dehydrogenase. Methods Enzymol (1988) 0.83
Acetylcholine as a brain state modulator: triggering and long-term regulation of REM sleep. Prog Brain Res (1993) 0.80
Wild-type and hexahistidine-tagged derivatives of leucine-responsive regulatory protein from Escherichia coli. Methods Enzymol (2000) 0.79
Cholinergic microstimulation of the peribrachial nucleus in the cat. I. Immediate and prolonged increases in ponto-geniculo-occipital waves. Arch Ital Biol (1992) 0.79
Effect of DNA superhelicity on transcription termination. Mol Gen Genet (1987) 0.78
Sequence determinants of DNA bending in the ilvlH promoter and regulatory region of Escherichia coli. Nucleic Acids Res (1994) 0.78
Long-term enhancement of REM sleep following cholinergic stimulation. Neuroreport (1991) 0.78
Habituation to bearable experimental pain elicited by tooth pulp electrical stimulation. Pain (1981) 0.78
Escherichia coli Lrp (leucine-responsive regulatory protein) does not directly regulate expression of the leu operon promoter. J Bacteriol (1999) 0.77
The role of the temporal lobe amygdala in ponto-geniculo-occipital activity and sleep organization in cats. Brain Res (1987) 0.76
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[Experimental models of epilepsy]. Gac Med Mex (1993) 0.75
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Amygdaloid kindling during rapid eye movement (REM) sleep in cats. Neurosci Lett (1982) 0.75
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Electrophysiologic effects, clinical efficacy and safety of intravenous and oral nadolol in refractory supraventricular tachyarrhythmias. Am J Cardiol (1987) 0.75
Kindling in the spinal cord: differential effects on mono- and polysynaptic reflexes and its modifications by atropine and naloxone. Electroencephalogr Clin Neurophysiol Suppl (1982) 0.75
Alpha-isopropylmalate synthase from Salmonella typhimurium--amino acid composition, NH 2 -terminal analysis, and fingerprint analysis. Biochim Biophys Acta (1971) 0.75
[Sleep and its disorders]. Gac Med Mex (1992) 0.75
Anatomical organization of the phasic activity produced by reserpine at the level of the oculomotor system. Electroencephalogr Clin Neurophysiol (1976) 0.75
Effects of diphenylhydantoin on the spontaneous activity of Purkinje, nucleus interpositus, red nucleus and motor cortex cells. Electroencephalogr Clin Neurophysiol (1979) 0.75
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A prospective evaluation of single and dual current pathways for transvenous cardioversion in rapid ventricular tachycardia. Pacing Clin Electrophysiol (1987) 0.75
Effects of two antidepressants on the different sleep stages in healthy human subjects. Bol Estud Med Biol (1978) 0.75
Massed amygdaloid kindling in encéphale isolé cats: its facilitation by naloxone. Epilepsy Res (1989) 0.75