Published in J Bacteriol on March 01, 1969
Linkage map of Salmonella typhimurium, edition IV. Bacteriol Rev (1972) 6.89
Current linkage map of Salmonella typhimurium. Bacteriol Rev (1970) 4.60
Genetic studies of leucine biosynthesis in Bacillus subtilis. J Bacteriol (1973) 3.90
leu operon of Salmonella typhimurium is controlled by an attenuation mechanism. Proc Natl Acad Sci U S A (1979) 2.91
Pleiotropy of hisT mutants blocked in pseudouridine synthesis in tRNA: leucine and isoleucine-valine operons. Proc Natl Acad Sci U S A (1974) 2.31
Mutants of Salmonella typhimurium with an altered leucyl-transfer ribonucleic acid synthetase. J Bacteriol (1971) 2.19
Physical characterization of the ilvHI operon of Escherichia coli K-12. J Bacteriol (1981) 1.85
Unusual organization of the ilvIH promoter of Escherichia coli. J Bacteriol (1985) 1.68
Methionine-mediated repression in Saccharomyces cerevisiae: a pleiotropic regulatory system involving methionyl transfer ribonucleic acid and the product of gene eth2. J Bacteriol (1971) 1.60
Amino acid biosynthesis in the spirochete Leptospira: evidence for a novel pathway of isoleucine biosynthesis. J Bacteriol (1974) 1.60
A new map location for the ilvB locus of Escherichia coli. Genetics (1980) 1.54
Isoleucine and valine metabolism in Escherichia coli. 18. Induction of acetohydroxy acid isomeroreductase. J Bacteriol (1972) 1.48
Effect of serine hydroxamate on the growth of Escherichia coli. J Bacteriol (1971) 1.46
Valine accumulation by alpha-aminobutyric acid-resistant mutants of Serratia marcescens. J Bacteriol (1971) 1.33
Temperature-sensitive growth inhibition by valine in Salmonella typhimurium: alteration of one form of acetohydroxy acid synthetase. J Bacteriol (1973) 1.33
Isoleucine hydroxamate, an isoleucine antagonist. J Bacteriol (1971) 1.30
Derepressed levels of the isoleucine-valine and leucine enzymes in his T 1504, a strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid. J Bacteriol (1974) 1.27
An indispensable gene for NAD biosynthesis in Salmonella typhimurium. J Bacteriol (1983) 1.22
IlvHI locus of Salmonella typhimurium. J Bacteriol (1983) 1.21
Isolation and characterization of lambda pleu bacteriophages. J Bacteriol (1977) 1.16
Leucyl-transfer ribonucleic acid synthetase from a wild-type and temperature-sensitive mutant of Salmonella typhimurium. J Bacteriol (1972) 1.14
Control of isoleucine, valine, and leucine biosynthesis. VI. Effect of 5',5',5'-trifluoroleucine on repression in Salmonella typhimurium. J Bacteriol (1969) 1.12
Leucine synthesis in Corynebacterium glutamicum: enzyme activities, structure of leuA, and effect of leuA inactivation on lysine synthesis. Appl Environ Microbiol (1994) 1.11
New amino acid regulatory locus having unusual properties in heterozygous merodiploids. J Bacteriol (1972) 1.09
1-Methylguanosine deficiency of tRNA influences cognate codon interaction and metabolism in Salmonella typhimurium. J Bacteriol (1995) 1.09
Regulation of leucine biosynthesis in Bacillus subtilis. J Bacteriol (1973) 1.03
Biosynthesis of the branched-chain amino acids in yeast: a trifluoroleucine-resistant mutant with altered regulation of leucine uptake. J Bacteriol (1970) 1.00
Mutations that convert the four leucine codons of the Salmonella typhimurium leu leader to four threonine codons. J Bacteriol (1985) 1.00
Relationship between messenger ribonucleic acid and enzyme levels specified by the leucine operon of Escherichia coli K-12. J Bacteriol (1977) 1.00
flrB, a regulatory locus controlling branched-chain amino acid biosynthesis in Salmonella typhimurium. J Bacteriol (1974) 0.99
Effect of cyclopentaneglycine on metabolism in Salmonella typhimurium. J Bacteriol (1972) 0.98
Transcription attenuation in Salmonella typhimurium: the significance of rare leucine codons in the leu leader. Proc Natl Acad Sci U S A (1986) 0.97
A new locus (leuK) affecting the regulation of branched-chain amino acid, histidine, and tryptophan biosynthetic enzymes. J Bacteriol (1978) 0.95
Effect of 4-azaleucine upon leucine metabolism in Salmonella typhimurium. J Bacteriol (1971) 0.95
A promoter relay mechanism for sequential gene activation. J Bacteriol (1998) 0.93
Global versus local regulatory roles for Lrp-related proteins: Haemophilus influenzae as a case study. J Bacteriol (2001) 0.92
Evidence that repression mechanisms can exert control over the thr, leu, and ilv operons of Escherichia coli K-12. J Bacteriol (1983) 0.91
Genetics of leucine biosynthesis in Bacillus megaterium QM B1551. J Bacteriol (1984) 0.90
Enzymes of the isoleucine-valine pathway in Acinetobacter. J Bacteriol (1972) 0.88
Escherichia coli B/r leuK mutant lacking pseudouridine synthase I activity. J Bacteriol (1986) 0.86
Transcription attenuation-mediated control of leu operon expression: influence of the number of Leu control codons. J Bacteriol (1991) 0.85
Analysis of regulation of the ilvGMEDA operon by using leader-attenuator-galK gene fusions. J Bacteriol (1990) 0.80
Biosynthesis of kitasamycin (leucomycin) by leucine analog-resistant mutants of Streptomyces kitasatoensis. Antimicrob Agents Chemother (1979) 0.79
Phase shift of the circadian rhythm of lemna caused by pulses of a leucine analog, trifluoroleucine. Plant Physiol (1988) 0.78
Synthesis and activities of branched-chain aminoacyl-tRNA synthetases in threonine deaminase mutants of Escherichia coli. J Bacteriol (1978) 0.77
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
A proposal for a uniform nomenclature in bacterial genetics. Genetics (1966) 31.92
Isolation of the lac repressor. Proc Natl Acad Sci U S A (1966) 10.20
ISOLATION OF THE lambda PHAGE REPRESSOR. Proc Natl Acad Sci U S A (1967) 7.57
Roles of amino acid activating enzymes in cellular physiology. Bacteriol Rev (1966) 7.00
Control of isoleucine, valine, and leucine biosynthesis. I. Multivalent repression. Proc Natl Acad Sci U S A (1962) 6.90
REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF ISOLEUCINE AND VALINE. II. IDENTIFICATION OF TWO OPERATOR GENES. J Bacteriol (1965) 6.02
Genetic fine structure of the leucine operon in Salmonella. Genetics (1963) 5.78
Revised linkage map of Salmonella typhimurium. Bacteriol Rev (1967) 5.22
Isoleucine and valine metabolism in Escherichia coli. X. The enzymatic formation of acetohydroxybutyrate. J Biol Chem (1961) 4.27
ROLE OF VALYL-SRNA SYNTHETASE IN ENZYME REPRESSION. Proc Natl Acad Sci U S A (1965) 3.82
Histidine regulatory mutants in Salmonella typhimurium 3. A class of regulatory mutants deficient in tRNA for histidine. J Mol Biol (1966) 3.80
Isoleucine and valine metabolism of Escherichia coli. XV. Biochemical properties of mutants resistant to thiaisoleucine. J Bacteriol (1968) 3.70
THE BIOSYNTHESIS OF LEUCINE. III. THE CONVERSION OF ALPHA-HYDROXY-BETA-CARBOXYISOCAPROATE TO ALPHA-KETOISOCAPROATE. Biochemistry (1964) 3.38
Mutants of Escherichia coli with an altered tryptophanyl-transfer ribonucleic acid synthetase. J Bacteriol (1968) 3.27
Isoleucine and valine metabolism of Escherichia coli. XVI. Pattern of multivalent repression in strain K-12. J Bacteriol (1968) 3.15
Expression of the leucine operon. J Bacteriol (1966) 3.12
BIOCHEMICAL ASPECTS OF GENETICS: THE OPERON. Annu Rev Biochem (1964) 3.07
ON THE INCORPORATION OF 5',5',5'-TRIFLUOROLEUCINE INTO PROTEINS OF E. COLI. Biochemistry (1964) 2.92
Valyl-Transfer RNA: Role in Repression of the Isoleucine-Valine Enzymes in Escherichia coli. Science (1967) 2.30
Interference with feedback control of enzyme activity. Cold Spring Harb Symp Quant Biol (1961) 1.95
Enzymatic formation of alpha-isopropylmalic acid, an intermediate in leucine biosynthesis. J Biol Chem (1963) 1.46
Lack of end-product inhibition and repression of leucine synthesis in a strain of Salmonella typhimurium. Science (1967) 1.17
Nucleotide sequence of the E coli gene coding for dihydrofolate reductase. Nucleic Acids Res (1980) 8.75
A large family of bacterial activator proteins. Proc Natl Acad Sci U S A (1988) 8.19
Amino acid biosynthesis and its regulation. Annu Rev Biochem (1978) 7.13
Compounds which serve as the sole source of carbon or nitrogen for Salmonella typhimurium LT-2. J Bacteriol (1969) 5.99
Isoleucine and valine metabolism of Escherichia coli. XV. Biochemical properties of mutants resistant to thiaisoleucine. J Bacteriol (1968) 3.70
Isoleucine and valine metabolism of Escherichia coli. XVI. Pattern of multivalent repression in strain K-12. J Bacteriol (1968) 3.15
Expression of the leucine operon. J Bacteriol (1966) 3.12
Isoleucine and valine metabolism of Escherichia coli. XIV. Effect of thiaisoleucine. J Bacteriol (1968) 2.98
leu operon of Salmonella typhimurium is controlled by an attenuation mechanism. Proc Natl Acad Sci U S A (1979) 2.91
Regulation of amino acid metabolism. Annu Rev Biochem (1969) 2.88
Characterization of Lrp, and Escherichia coli regulatory protein that mediates a global response to leucine. J Biol Chem (1991) 2.83
Polarity and the regulation of the ilv gene cluster in Escherichia coli strain K-12. Mol Gen Genet (1976) 2.78
The ilvIH operon of Escherichia coli is positively regulated. J Bacteriol (1990) 2.71
Alternative secondary structures of leader RNAs and the regulation of the trp, phe, his, thr, and leu operons. Proc Natl Acad Sci U S A (1979) 2.71
Nucleotide sequence of ilvGEDA operon attenuator region of Escherichia coli. Proc Natl Acad Sci U S A (1980) 2.61
Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic operon controlled by attenuation and cyclic AMP. Proc Natl Acad Sci U S A (1982) 2.50
Molecular structure of ilvIH and its evolutionary relationship to ilvG in Escherichia coli K12. Nucleic Acids Res (1983) 2.39
Regulation of isoleucine-valine biosynthesis in an ilvDAC deletion strain of Escherichia coli K-12. Biochem Biophys Res Commun (1974) 2.35
Isoleucine and valine metabolism in Escherichia coli. XXII. A pleiotropic mutation affecting induction of isomeroreductase activity. J Bacteriol (1973) 2.31
Pleiotropy of hisT mutants blocked in pseudouridine synthesis in tRNA: leucine and isoleucine-valine operons. Proc Natl Acad Sci U S A (1974) 2.31
Valyl-Transfer RNA: Role in Repression of the Isoleucine-Valine Enzymes in Escherichia coli. Science (1967) 2.30
Biosynthesis of branched-chain amino acids in yeast: correlation of biochemical blocks and genetic lesions in leucine auxotrophs. J Bacteriol (1968) 2.25
Mutants of Salmonella typhimurium with an altered leucyl-transfer ribonucleic acid synthetase. J Bacteriol (1971) 2.19
A multisite-mutation map of the leucine operon of Salmonella typhimurium. Genetics (1970) 2.17
Lrp, a global regulatory protein of Escherichia coli, binds co-operatively to multiple sites and activates transcription of ilvIH. J Mol Biol (1993) 2.17
Biosynthesis of branched-chain amino acids in yeast: regulation of leucine biosynthesis in prototrophic and leucine auxotrophic strains. J Bacteriol (1968) 2.13
Isoleucine and valine metabolism in Escherichia coli. XX. Multiple forms of acetohydroxy acid synthetase. Biochem Biophys Res Commun (1972) 2.07
Control of leu operon expression in Escherichia coli by a transcription attenuation mechanism. J Mol Biol (1981) 2.01
Transcriptional regulation of the ilv-leu operon of Bacillus subtilis. J Bacteriol (1992) 1.96
The metabolism of valine and isoleucine in Escherichia coli. XVII. The role of induction in the derepression of acetohydroxy acid isomeroreductase. Biochem Biophys Res Commun (1969) 1.94
Two forms of biosynthetic acetohydroxy acid synthetase in Salmonella typhimurium. Biochem Biophys Res Commun (1972) 1.94
Purification and properties of the acetohydroxy acid isomeroreductase of Salmonella typhimurium. J Biol Chem (1969) 1.92
Acetohydroxy acid synthase I of Escherichia coli: purification and properties. J Bacteriol (1979) 1.90
A consensus sequence for binding of Lrp to DNA. J Bacteriol (1995) 1.88
Mechanism for the autogenous control of the crp operon: transcriptional inhibition by a divergent RNA transcript. Proc Natl Acad Sci U S A (1986) 1.88
Regulation of transaminase C synthesis in Escherichia coli: conditional leucine auxotrophy. J Bacteriol (1974) 1.88
Physical characterization of the ilvHI operon of Escherichia coli K-12. J Bacteriol (1981) 1.85
Operator constitutive mutations in the leucine operon of Salmonella typhimurium. Genetics (1969) 1.84
Acetohydroxy acid synthase isoenzymes of Escherichia coli K12 and Salmonella typhimurium. Ann Microbiol (Paris) (1982) 1.82
The nucleotide sequence of a rat myosin light chain 2 gene. Nucleic Acids Res (1984) 1.81
Leucine-responsive regulatory protein controls the expression of both the pap and fan pili operons in Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.81
Mutations affecting the formation of acetohydroxy acid synthase II in Escherichia coli K-12. Mol Gen Genet (1979) 1.81
Regions of the Bacillus subtilis ilv-leu operon involved in regulation by leucine. J Bacteriol (1993) 1.76
Isoleucine and valine metabolism in Escherichia coli. XXI. Mutations affecting derepression and valine resistance. J Bacteriol (1973) 1.75
Fluorometric assay of enzymatic reactions involving acetyl Coenzyme A in aldol condensations. Anal Biochem (1969) 1.75
A protein that binds to the regulatory region of the Escherichia coli ilvIH operon. J Bacteriol (1989) 1.75
Role of threonine deaminase in the regulation of isoleucine and valine biosynthesis. Nat New Biol (1973) 1.75
Physical organization of the ilvEDAC genes of Escherichia coli strain K-12. Proc Natl Acad Sci U S A (1978) 1.74
Lrp, a leucine-responsive protein, regulates branched-chain amino acid transport genes in Escherichia coli. J Bacteriol (1992) 1.74
Lrp, a major regulatory protein in Escherichia coli, bends DNA and can organize the assembly of a higher-order nucleoprotein structure. EMBO J (1993) 1.74
Mutations affecting the ability of Escherichia coli Lrp to bind DNA, activate transcription, or respond to leucine. J Bacteriol (1993) 1.70
Unusual organization of the ilvIH promoter of Escherichia coli. J Bacteriol (1985) 1.68
Effects of nutrition and growth rate on Lrp levels in Escherichia coli. J Bacteriol (1996) 1.67
Isoleucine and valine metabolism in Escherichia coli. XIX. Inhibition of isoleucine biosynthesis by glycyl-leucine. J Bacteriol (1972) 1.65
Positive control of ilvC expression in Escherichia coli K-12; identification and mapping of regulatory gene ilvY. J Bacteriol (1979) 1.64
Characterization of the 3' end of the leucine operon of Salmonella typhimurium. Mol Gen Genet (1985) 1.63
Intracellular Regulatory Mechanisms: Regulation in multicellular forms may be an elaboration upon the pattern evolved in microorganisms. Science (1964) 1.63
Regulation of cyclic AMP of the ilvB-encoded biosynthetic acetohydroxy acid synthase in Escherichia coli K-12. Mol Gen Genet (1980) 1.63
Alpha-isopropylmalate synthase from Salmonella typhimurium. Purification and properties. J Biol Chem (1969) 1.62
Regulation of the Escherichia coli lrp gene. J Bacteriol (1994) 1.56
Restriction endonuclease mapping of the Escherichia coli K12 chromosome in the vicinity of the ilv genes. J Mol Biol (1977) 1.54
Regulation of dihydrofolate reductase synthesis in Escherichia coli. Mol Gen Genet (1979) 1.53
The ilvB locus of Escherichia coli K-12 is an operon encoding both subunits of acetohydroxyacid synthase I. Nucleic Acids Res (1985) 1.49
On the role of isoleucyl-tRNA synthetase in multivalent repression. Biochem Genet (1972) 1.48
Isoleucine and valine metabolism in Escherichia coli. 18. Induction of acetohydroxy acid isomeroreductase. J Bacteriol (1972) 1.48
Metabolite analogs as genetic and biochemical probes. Adv Genet (1971) 1.48
Reduced expression of the isoleucine and valine enzymes in integration host factor mutants of Escherichia coli. J Mol Biol (1984) 1.45
Threonine deaminases. Adv Enzymol Relat Areas Mol Biol (1973) 1.43
Cloning and expression of the ilvB gene of Escherichia coli K-12. Mol Gen Genet (1982) 1.42
Separate regulation of transport and biosynthesis of leucine, isoleucine, and valine in bacteria. J Bacteriol (1975) 1.41
Location of the multivalent control site for the ilvEDA operon of Escherichia coli. J Bacteriol (1980) 1.41
Evidence for channeling of homoserine in Salmonella typhimurium. Biochim Biophys Acta (1970) 1.40
Effect of isoleucine, valine, or leucine starvation on the potential for formation of the branched-chain amino acid biosynthetic enzymes. J Bacteriol (1973) 1.33
Physical characterization of ilv-lac fusions. J Bacteriol (1979) 1.33
Temperature-sensitive growth inhibition by valine in Salmonella typhimurium: alteration of one form of acetohydroxy acid synthetase. J Bacteriol (1973) 1.33
Control of isoleucine, valine and leucine biosynthesis. 8. Mechanism of growth inhibition by leucine in relaxed and stringent strains of Escherichia coli K-12. Biochim Biophys Acta (1970) 1.33
Isoleucine and valine metabolism in Escherichia coli K-12: detection and measurement of ilv-specific messenger ribonucleic acid. J Bacteriol (1974) 1.30
Salmonella locus affecting phosphoenolpyruvate synthase activity identified by a deletion analysis. J Bacteriol (1971) 1.30
Physical location of the ilvO determinant in Escherichia coli K-12 deoxyribonucleic acid. J Bacteriol (1980) 1.29
Characterization of fusions between the lac operon and the ilv gene cluster in Escherichia coli: ilvC-lac fusions. J Bacteriol (1977) 1.28
Derepressed levels of the isoleucine-valine and leucine enzymes in his T 1504, a strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid. J Bacteriol (1974) 1.27
COLORIMETRIC METHOD FOR THE ESTIMATION OF GROWTH IN CUP ASSAYS. J Bacteriol (1960) 1.26
The ilvIH operon of Escherichia coli K-12. Identification of the gene products and recognition of the translational start by polypeptide microsequencing. Biochim Biophys Acta (1985) 1.25
Altered osmoregulation of ompF in integration host factor mutants of Escherichia coli. J Bacteriol (1988) 1.24
Cyclic AMP can replace the relA-dependent requirement for derepression of acetohydroxy acid synthase in E. coli K-12. Cell (1977) 1.24
Role for free isoleucine of glycyl-leucine in the repression of threonine deaminase in Escherichia coli. J Bacteriol (1974) 1.22
A role for a pyridoxne derivative in the multivalent repression of the isoleucine and valine biosynthetic enzymes. Biochem Biophys Res Commun (1973) 1.22
IlvHI locus of Salmonella typhimurium. J Bacteriol (1983) 1.21
The nucleotide sequence of leuA from Salmonella typhimurium. Nucleic Acids Res (1990) 1.20
Leucine-regulated self-association of leucine-responsive regulatory protein (Lrp) from Escherichia coli. J Mol Biol (2001) 1.20
Transcription attenuation is the major mechanism by which the leu operon of Salmonella typhimurium is controlled. J Mol Biol (1983) 1.18
Biosynthesis of branched-chain amino acids in yeast: regulation of synthesis of the enzymes of isoleucine and valine biosynthesis. J Bacteriol (1969) 1.18
Lack of end-product inhibition and repression of leucine synthesis in a strain of Salmonella typhimurium. Science (1967) 1.17
Integration host factor is required for anaerobic pyruvate induction of pfl operon expression in Escherichia coli. J Bacteriol (1993) 1.17
Biosynthesis of branched-chain amino acids in yeast: effect of carbon source on leucine biosynthetic enzymes. J Bacteriol (1975) 1.17
Isolation and characterization of lambda pleu bacteriophages. J Bacteriol (1977) 1.16
Integration host factor is a negative effector of in vivo and in vitro expression of ompC in Escherichia coli. J Bacteriol (1990) 1.16
Transcriptional activation by FNR and CRP: reciprocity of binding-site recognition. Mol Microbiol (1997) 1.16