Published in Gut on October 01, 1969
Diverticular disease of the colon: a deficiency disease of Western civilization. Br Med J (1971) 9.82
Measurement of the mean transit time of dietary residue through the human gut. Gut (1976) 4.22
American Gastroenterological Association technical review on constipation. Gastroenterology (2013) 3.27
Irritable bowel syndrome: relationship of disorders in the transit of a single solid meal to symptom patterns. Gut (1983) 2.93
Severe chronic constipation of young women: 'idiopathic slow transit constipation'. Gut (1986) 2.45
Transit through the gut measured by analysis of a single stool. Gut (1976) 2.36
The effect of wheat bran on intestinal transit. Gut (1975) 2.10
Propulsion (mass movements) in the human colon and its relationship to meals and somatic activity. Gut (1970) 2.05
Effects of dietary supplements of wheat bran and cellulose on faeces and bowel function. Br Med J (1973) 2.04
Action of different bran preparations on colonic function. Br Med J (1974) 1.99
Bran tablets and diverticular disease. Br Med J (1976) 1.96
What is the benefit of coarse wheat bran in patients with irritable bowel syndrome? Gut (1984) 1.96
Intestinal streaming patterns in cholerrhoeic enteropathy and diverticular disease. Gut (1974) 1.95
Evaluation and surgical treatment of severe chronic constipation. Ann Surg (1991) 1.92
Methane excretion in man--a study of breath, flatus, and faeces. Gut (1985) 1.88
Variability of colonic function in healthy subjects. Gut (1978) 1.82
Outcome of colectomy for severe idiopathic constipation. Gut (1988) 1.82
Dietary fibre. Gut (1973) 1.77
Radioisotope determination of regional colonic transit in severe constipation: comparison with radio opaque markers. Gut (1993) 1.71
Variability of gastrointestinal transit in healthy women and men. Gut (1996) 1.63
Balloon expulsion from the rectum in constipation of different types. Gut (1985) 1.51
Is there a myoelectrical abnormality in the irritable colon syndrome? Gut (1978) 1.49
Colonic transit studies: normal values for adults and children with comparison of radiological and scintigraphic methods. Pediatr Surg Int (2009) 1.46
Double blind study of ispaghula in irritable bowel syndrome. Gut (1987) 1.35
Investigation of disorders of the anorectum and colon. Ann R Coll Surg Engl (1985) 1.30
Wireless pH-motility capsule for colonic transit: prospective comparison with radiopaque markers in chronic constipation. Neurogastroenterol Motil (2010) 1.29
What is necessary to diagnose constipation? Best Pract Res Clin Gastroenterol (2011) 1.27
Effects of gender and menstrual cycle on colonic transit time in healthy subjects. Korean J Intern Med (2003) 1.26
Postoperative motility of the large intestine in man. Gut (1975) 1.24
Measurement of gastrointestinal transit. Dig Dis Sci (2005) 1.20
Rectal prolapse: a 10-year experience. Ochsner J (2007) 1.20
Colonic motility. Gut (1975) 1.20
Prognosis of constipation: clinical factors and colonic transit time. Arch Dis Child (2004) 1.19
Appendicitis, fibre intake and bowel behaviour in ethnic groups in South Africa. Postgrad Med J (1973) 1.19
Current status of functional gastrointestinal evaluation in clinical practice. Singapore Med J (2015) 1.19
Oral domperidone: double blind comparison with placebo in irritable bowel syndrome. Gut (1983) 1.17
Sterculia bulk-forming agent with smooth-muscle relaxant versus bran in diverticular disease. Br Med J (1976) 1.16
The physical state of bile acids in the diarrhoeal stool of ileal dysfunction. Gut (1973) 1.14
Comparison of bran, ispaghula, and lactulose on colon function in diverticular disease. Gut (1978) 1.11
Tea consumption: a cause of constipation? Br Med J (Clin Res Ed) (1981) 1.07
Comparison of rectosigmoid myoelectrical activity in the irritable colon syndrome during relapses and remissions. Gut (1978) 1.06
Diverticular disease: threee studies. Part II - Treatment with bran. Br Med J (1976) 1.06
Bowel transit times in Bantu populations. Br Med J (1970) 1.06
Differential measurement of small and large bowel transit times in constipation and diarrhoea: A new approach. Gut (1975) 1.04
Relationships between symptoms, menstrual cycle and orocaecal transit in normal and constipated women. Gut (1989) 1.03
The pathophysiology of chronic constipation. Can J Gastroenterol (2011) 1.02
Colonic elongation inhibits pellet propulsion and migrating motor complexes in the murine large bowel. J Physiol (2010) 1.01
Is encopresis always the result of constipation? Arch Dis Child (1994) 1.01
Medical and surgical management of pelvic floor disorders affecting defecation. Am J Gastroenterol (2012) 0.99
Gastrointestinal transit of Oros drug delivery systems in healthy volunteers: a short report. Br J Clin Pharmacol (1985) 0.99
Consensus statement AIGO/SICCR: diagnosis and treatment of chronic constipation and obstructed defecation (part I: diagnosis). World J Gastroenterol (2012) 0.99
Pathophysiology of colonic causes of chronic constipation. Neurogastroenterol Motil (2009) 0.99
The high fibre diet in the treatment of diverticular disease of the colon. Postgrad Med J (1974) 0.98
How to interpret a functional or motility test - colon transit study. J Neurogastroenterol Motil (2012) 0.98
Hand-assisted laparoscopic total colectomy for slow transit constipation. Int J Colorectal Dis (2008) 0.97
Faecal unconjugated bile acids in patients with colorectal cancer or polyps. Gut (1992) 0.97
Positive correlation between symptoms and circulating motilin, pancreatic polypeptide and gastrin concentrations in functional bowel disorders. Gut (1985) 0.96
Diarrhoea: mechanisms and treatment. Gut (1971) 0.96
Human colonic motility: physiological aspects. Int J Colorectal Dis (1995) 0.95
Bowel management in the neurologically disabled. The problems of old age. Proc R Soc Med (1972) 0.95
Dynamic scanning defines a colonic defect in severe idiopathic constipation. Gut (1988) 0.95
Effect of enterocoated cholestyramine on bowel habit after ileal resection: a double blind crossover study. Br Med J (Clin Res Ed) (1985) 0.92
Effect of hysterectomy on anorectal and urethrovesical physiology. Gut (1992) 0.91
Epidemiology and management of chronic constipation in elderly patients. Clin Interv Aging (2015) 0.91
Methods for the assessment of small-bowel and colonic transit. Semin Nucl Med (2012) 0.91
Multiple sclerosis: assessment of colonic and anorectal function in the presence of faecal incontinence. Int J Colorectal Dis (1993) 0.90
Effects of a meal and bisacodyl on colonic motility in healthy volunteers and patients with slow-transit constipation. Dig Dis Sci (2003) 0.90
Steroid hormone abnormalities in women with severe idiopathic constipation. Gut (1991) 0.90
Techniques in evacuation proctography in the diagnosis of intractable constipation and related disorders. J R Soc Med (1986) 0.89
Intracolonic environment and the presence of colonic adenomas in man. Gut (1983) 0.89
Anterior rectocele and anorectal dysfunction. Int J Colorectal Dis (1996) 0.89
Effects of two types of dietary fibre on faecal steroid and lipid excretion. Br Med J (1975) 0.88
The investigation of anorectal dysfunction in the solitary rectal ulcer syndrome. Int J Colorectal Dis (1990) 0.88
Colon transit time in healthy children and adolescents. Int J Colorectal Dis (2013) 0.88
Evidence for motor neuropathy and reduced filling of the rectum in chronic intractable constipation. Gut (1990) 0.88
Colon specific delivery of indomethacin: effect of incorporating pH sensitive polymers in xanthan gum matrix bases. AAPS PharmSciTech (2009) 0.88
What is chronic constipation? Definition and diagnosis. Can J Gastroenterol (2011) 0.86
Effect of codeine phosphate, Lomotil, and Isogel on iileostomy function. Gut (1978) 0.85
The effect of preliminary bowel preparation on a simple test of colonic transit in constipated subjects. Int J Colorectal Dis (1993) 0.85
Advances in motility testing--current and novel approaches. Nat Rev Gastroenterol Hepatol (2013) 0.85
Motility effects of operations performed for diverticular disease. Proc R Soc Med (1974) 0.85
Prevention of aspirin-induced faecal blood loss by prostaglandin E2. Gut (1980) 0.85
Colectomy for slow transit constipation. Ann R Coll Surg Engl (1987) 0.84
Colonic manometry in children with chronic intestinal pseudo-obstruction. Gut (1993) 0.84
The surgical treatment of severe idiopathic constipation. Int J Colorectal Dis (1987) 0.83
Colonic motility: practice or research? Gut (1993) 0.83
Colonic Transit Study Technique and Interpretation: Can These Be Uniform Globally in Different Populations With Non-uniform Colon Transit Time? J Neurogastroenterol Motil (2012) 0.83
Colonic myoelectrical activity in IBS painless diarrhoea. Gut (1987) 0.82
Methods in human alimentary motility. Br J Clin Pharmacol (1982) 0.82
Paradoxical puborectalis contraction is a feature of constipation in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry (1996) 0.82
Scintigraphic assessment of colonic function during defaecation. Int J Colorectal Dis (1995) 0.81
Objective evaluation of small bowel and colonic transit time using pH telemetry in athletes with gastrointestinal symptoms. Br J Sports Med (2004) 0.81
Assessment of colonic transit time using MRI: a feasibility study. Eur Radiol (2006) 0.80
Degradation of cellulose within the gastrointestinal tract in man. Gut (1984) 0.80
The role of dietary fibre in the prevention and treatment of diseases of the colon. Proc R Soc Med (1973) 0.80
Assessment of simple methods of measuring intestinal transit times in children with gastroenteritis. Gut (1975) 0.80
Paradoxical sphincter reaction and associated colorectal disorders. Int J Colorectal Dis (1992) 0.80
Clinical pharmacology of daikenchuto assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study). J Gastroenterol (2015) 0.79
Experience with the chromic oxide method of fecal marking in metabolic balance investigations on humans. J Clin Invest (1960) 4.77
Transit times of food in patients with diverticulosis or irritable colon syndrome and normal subjects. Br Med J (1967) 3.51
Measurement of gastrointestinal transit using radioactive chromium. Gut (1962) 3.19
Study of urinary and fecal excretion of radioactive chromium Cr51 in man; its use in the measurement of intestinal blood loss associated with hookworm infection. J Clin Invest (1957) 3.15
Usefulness of chromic oxide as an internal standard for balance studies in formula-fed patients and for assessment of colonic function. J Clin Invest (1968) 3.00
Use of barium sulphate as a continuous marker for faeces. J Clin Pathol (1967) 2.79
Constipation: definition and classification. Postgrad Med J (1968) 2.27
Laxatives and anti-diarrhoeal agents: transit studies. Proc R Soc Med (1967) 2.08
Intestinal absorption of trace quantities of chromium. J Lab Clin Med (1966) 1.99
LANTHANUM-140 AS A MEASURE OF THE COMPLETENESS OF STOOL COLLECTIONS. DEMONSTRATION OF DELAYED EXCRETION OF IRON-59. J Nucl Med (1964) 1.72
Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature (1990) 13.60
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet (2001) 7.27
Identification of a family of muscarinic acetylcholine receptor genes. Science (1987) 6.21
Variation of bowel habit in two population samples. Br Med J (1965) 5.78
Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature (1996) 5.44
Factors affecting the outcome of endoscopic surveillance for cancer in ulcerative colitis. Gastroenterology (1994) 3.44
Low incidence of osteoarthrosis in hip and knee after anterior poliomyelitis: a late review. Br Med J (1966) 3.41
Prognosis after resection of chronic regional ileitis. Gut (1967) 3.27
Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes. Neuron (1988) 3.27
Clinical and pathological differentiation of Crohn's disease and proctocolitis. Gastroenterology (1968) 3.20
Anismus in chronic constipation. Dig Dis Sci (1985) 3.16
Experience in the treatment of Crohn's disease of the large intestine. Gut (1966) 3.14
Mycobacteria as a possible cause of inflammatory bowel disease. Lancet (1978) 2.94
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. Am J Hum Genet (1999) 2.88
Risk of malignant change in ulcerative colitis. Gut (1966) 2.86
A comparison of oral prednisolone given as single or multiple daily doses for active proctocolitis. Scand J Gastroenterol (1978) 2.73
Cancer surveillance in ulcerative colitis. Experience over 15 years. Lancet (1983) 2.67
Cancer in colitis: assessment of the individual risk by clinical and histological criteria. Gastroenterology (1977) 2.61
Jejunal efflux in short bowel syndrome. Lancet (1990) 2.52
The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene. Nucleic Acids Res (1986) 2.50
Severe chronic constipation of young women: 'idiopathic slow transit constipation'. Gut (1986) 2.45
Double-blind withdrawal trial of azathioprine as maintenance treatment for Crohn's disease. Lancet (1978) 2.40
Constipation: definition and classification. Postgrad Med J (1968) 2.27
Numerical taxonomy and discriminant analysis applied to non-specific colitis. Q J Med (1973) 2.26
Measurement of tryptic activity in intestinal juice as a diagnostic test of pancreatic disease. Gut (1967) 2.17
Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc Natl Acad Sci U S A (1992) 2.16
Laxatives and anti-diarrhoeal agents: transit studies. Proc R Soc Med (1967) 2.08
Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease. Lancet (1994) 2.04
Career prospects in medical gastroenterology in the UK: a follow up survey 1980-2. Gut (1983) 2.04
Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience. Gut (1993) 2.01
Clinical outcome of the first ten years of ulcerative colitis and proctitis. Lancet (1978) 1.99
Crohn's disease of the colon and its distinction from diverticulitis. Gut (1968) 1.95
Randomised controlled trial of azathioprine withdrawal in ulcerative colitis. BMJ (1992) 1.94
Tuberculin sensitivity in Crohn's disease. A controlled study. Lancet (1967) 1.89
Correlations between defined sigmoidoscopic appearances and other measures of disease activity in ulcerative colitis. Dig Dis Sci (1982) 1.85
Outcome of colectomy for severe idiopathic constipation. Gut (1988) 1.82
Dysplasia and deoxyribonucleic acid aneuploidy in the assessment of precancerous changes in chronic ulcerative colitis. Observer variation and correlations. Gastroenterology (1988) 1.81
Controlled trial of azathioprine in chronic ulcerative colitis. Br Med J (Clin Res Ed) (1982) 1.75
Faecal stasis in proctocolitis. Gut (1962) 1.71
Radioisotope determination of regional colonic transit in severe constipation: comparison with radio opaque markers. Gut (1993) 1.71
Towards a radiologic definition of idiopathic megacolon. Gastrointest Radiol (1985) 1.69
Potential candidates for small bowel transplantation. Br J Surg (1992) 1.69
Colonoscopic diagnosis of minimal change colitis in patients with a normal sigmoidoscopy and normal air-contrast barium enema. Lancet (1982) 1.68
Sexual problems among married ileostomists. Survey conducted by The Ileostomy Association of Great Britain and Ireland. Gut (1977) 1.67
Failure of rectal expulsion as a cause of constipation: why fibre and laxatives sometimes fail. Lancet (1986) 1.65
Team approach to long-term intravenous feeding in patients with gastrointestinal disorders. Lancet (1978) 1.65
Corticosteroids and corticotrophin in the treatment of Crohn's disease. Gut (1966) 1.64
Rectal mucosal electrosensory testing--evidence for a rectal sensory neuropathy in idiopathic constipation. Dis Colon Rectum (1990) 1.64
Gastrointestinal hormones in short bowel syndrome. Peptide YY may be the 'colonic brake' to gastric emptying. Gut (1996) 1.60
Results of colectomy for severe idiopathic constipation in women (Arbuthnot Lane's disease). Br J Surg (1984) 1.58
Linkage of inflammatory bowel disease to human chromosome 6p. Am J Hum Genet (1999) 1.57
Is routine computerised axial tomography in epilepsy worth while? Lancet (1982) 1.56
Some Factors in the Assessment of Gastric Antisecretory Drugs by a Sampling Technique. Gut (1960) 1.54
Balloon expulsion from the rectum in constipation of different types. Gut (1985) 1.51
Long-term parenteral nutrition: problems with venous access. J R Soc Med (1990) 1.51
Crohn's disease: natural history and treatment. Postgrad Med J (1968) 1.51
A practical approach to the risk of cancer in inflammatory bowel disease. Med Clin North Am (1980) 1.46
Restricted diffusion in biophysical systems. Experiment. Biophys J (1974) 1.44
Peptide-containing neurons in different regions of the submucous plexus of human sigmoid colon. Gastroenterology (1992) 1.44
Plasma prednisolone levels after administration of prednisolone-21-phosphate as a retention enema in colitis. Br Med J (1976) 1.42
Proctocolitis and Crohn's disease of the colon: a comparison of the clinical course. Gut (1976) 1.41
Inflammatory bowel disease in 67 families each with three or more affected first-degree relatives. Gastroenterology (1996) 1.40
Misdiagnosis of multiple sclerosis. Lancet (1997) 1.40
HLA and inflammatory bowel disease. Lancet (1996) 1.39
Safety of azathioprine in pregnancy in inflammatory bowel disease. Gastroenterology (1990) 1.35
Crohn's disease of the distal large bowel. Scand J Gastroenterol (1976) 1.35
Anovaginal and rectovaginal fistulas in Crohn's disease. Dis Colon Rectum (1988) 1.34
Prospective study of outpatients with extensive colitis. Lancet (1974) 1.34
Antineutrophil antibodies in familial inflammatory bowel disease. Gastroenterology (1995) 1.34
The normal range and a simple diagram for recording whole gut transit time. Int J Colorectal Dis (1992) 1.33
The balloon proctogram. Br J Surg (1984) 1.32
Studies of prostaglandins and sulphasalazine in ulcerative colitis. Prostaglandins Med (1981) 1.32
Assessment of severity in colitis: a preliminary study. Gut (1975) 1.30
Macroscopic lesions in dysplasia and carcinoma complicating ulcerative colitis. Dig Dis Sci (1983) 1.29
Colitis. Lancet (1978) 1.29
Modified technique for administration of retention enemata in colitis. Gut (1965) 1.28
Enema volume as an important factor in successful topical corticosteroid treatment of colitis. Proc R Soc Med (1974) 1.28
The prognosis of idiopathic proctitis. Scand J Gastroenterol (1977) 1.28
An indirect influence of phenylephrine on the release of endothelium-derived vasodilators in rat small mesenteric artery. Br J Pharmacol (2000) 1.27
Mechanial properties of alveolar walls. J Appl Physiol (1968) 1.27
Hirschsprung's disease and idiopathic megacolon in adults and adolescents. Gut (1986) 1.27
Experience of posterior division of the puborectalis muscle in the management of chronic constipation. Br J Surg (1985) 1.27
Patients appreciate premedication for endoscopy. Lancet (1980) 1.27
Radiologic studies of rectal evacuation in adults with idiopathic constipation. Dis Colon Rectum (1988) 1.26
Prognosis of carcinoma in ulcerative colitis. Gut (1981) 1.26
Management of enterocutaneous fistulas: a review of 132 cases. Br J Surg (1984) 1.24
Reversibility of radiological appearances during clinical improvement in colonic Crohn's disease. Gut (1969) 1.24
Variation of bowel habit in two population samples. Proc R Soc Med (1966) 1.23
Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease. Gut (2001) 1.23
Evacuation proctography: an investigation of rectal expulsion in 20 subjects without defecatory disturbance. Gastrointest Radiol (1988) 1.22
Clinicopathological characteristics of colorectal carcinoma complicating ulcerative colitis. Gut (1994) 1.22
miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis. Br J Cancer (2013) 1.21
Compliance, cost, and common sense limit cancer control in colitis. Gut (1986) 1.20