Published in Lancet on May 21, 1994
Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. Gut (2005) 3.86
Increased incidence of non-Hodgkin's lymphoma in inflammatory bowel disease patients on immunosuppressive therapy but overall risk is low. Gut (2000) 2.17
Cancer in inflammatory bowel disease. World J Gastroenterol (2008) 2.12
The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut (2002) 2.00
Infliximab in inflammatory bowel disease: clinical outcome in a population based cohort from Stockholm County. Gut (2004) 1.87
Risk of haematopoietic cancer in patients with inflammatory bowel disease. Gut (2005) 1.70
Review article: multiple myeloma and inflammatory bowel disease. Dig Dis Sci (2007) 1.64
Long-term risk of malignancy among patients treated with immunosuppressive agents for ocular inflammation: a critical assessment of the evidence. Am J Ophthalmol (2008) 1.56
Classification and management of refractory coeliac disease. Gut (2010) 1.48
Ulcerative colitis complicated by renal cell carcinoma: a series of three patients. Gut (1996) 1.46
New pathophysiological insights and modern treatment of IBD. J Gastroenterol (2010) 1.31
Inflammation is an independent risk factor for colonic neoplasia in patients with ulcerative colitis: a case-control study. Clin Gastroenterol Hepatol (2013) 1.17
Treating rheumatic patients with a malignancy. Arthritis Res Ther (2011) 1.03
Management of difficult inflammatory bowel disease: where are we now? World J Gastroenterol (2000) 0.90
Small bowel adenocarcinoma in Crohn's disease: a case report and review of literature. World J Gastroenterol (2006) 0.90
Use of thiopurines in inflammatory bowel disease. World J Gastroenterol (2013) 0.89
Thiopurines in inflammatory bowel disease revisited. World J Gastroenterol (2013) 0.88
Development of hepatocellular carcinoma in a patient with Crohn's disease treated with azathioprine. Dig Dis Sci (2007) 0.87
Intensive induction chemotherapy followed by early high-dose therapy and hematopoietic stem cell transplantation results in improved outcome for patients with hepatosplenic T-cell lymphoma: a single institution experience. Clin Lymphoma Myeloma Leuk (2012) 0.86
Medical treatment of ulcerative colitis. Clin Colon Rectal Surg (2004) 0.86
Are patients with inflammatory bowel disease on chronic immunosuppressive therapy at increased risk of cervical high-grade dysplasia/cancer? A meta-analysis. Inflamm Bowel Dis (2015) 0.85
Azathioprine in inflammatory bowel disease, a safe alternative? Mediators Inflamm (1998) 0.84
Management of inflammatory bowel disease. Postgrad Med J (2004) 0.83
Use of thiopurines and risk of colorectal neoplasia in patients with inflammatory bowel diseases: a meta-analysis. PLoS One (2013) 0.83
Management of Crohn's disease. BMJ (1999) 0.82
Dysplasia in ulcerative colitis--clinical consequences? Langenbecks Arch Surg (2004) 0.81
Gut-liver axis plays a role in hepatocarcinogenesis of patients with Crohn's disease. World J Gastroenterol (2011) 0.80
Update on the risk of lymphoma following immunosuppressive therapy for inflammatory bowel disease. Expert Rev Clin Immunol (2010) 0.80
Optimal Endpoint of Therapy in IBD: An Update on Factors Determining a Successful Drug Withdrawal. Gastroenterol Res Pract (2015) 0.79
Targeting Therapy in Pediatric Inflammatory Bowel Disease. Curr Treat Options Gastroenterol (2004) 0.79
Primary CD56+ NK/T-cell lymphoma of the rectum accompanied with refractory ulcerative colitis. J Gastroenterol (2008) 0.79
Normal colonic mucosa in hereditary non-polyposis colorectal cancer shows no generalised increase in somatic mutation. Br J Cancer (1995) 0.78
Treatment of Crohn's disease with leflunomide as second-line immunosuppression : a phase 1 open-label trial on efficacy, tolerability and safety. Dig Dis Sci (2007) 0.78
Hematological malignancies in chronic inflammatory bowel diseases: report of five cases and review of the literature. Int J Colorectal Dis (2006) 0.77
Long term results of use of azathioprine in patients with ulcerative colitis in India. World J Gastroenterol (2006) 0.76
Medical Therapy of Crohn's Disease. Curr Treat Options Gastroenterol (2005) 0.76
Antagonist: Early surgical intervention in ulcerative colitis. Gut (2004) 0.75
Thiopurines and inflammatory bowel disease: Current evidence and a historical perspective. World J Gastroenterol (2016) 0.75
Traditional Chinese medicine combination therapy for patients with steroid-dependent ulcerative colitis: study protocol for a randomized controlled trial. Trials (2017) 0.75
Hodgkin's lymphoma rectosigmoid in a patient with ulcerative colitis on long-term azathioprine therapy. BMJ Case Rep (2014) 0.75
Azathioprine is essential following cyclosporine for patients with steroid-refractory ulcerative colitis. World J Gastroenterol (2015) 0.75
A population-based study examining the risk of malignancy in patients diagnosed with inflammatory bowel disease. J Gastroenterol (2016) 0.75
Colitic cancer developed after introduction of azathioprine. Dig Dis Sci (2004) 0.75
Hematologic malignancies in the Japanese patients with inflammatory bowel disease. J Gastroenterol (2013) 0.75
Development of hepatocellular carcinoma following treatment with 6-mercaptopurine for ulcerative colitis: investigation of chromosomal aberration by comparative genomic hybridization. Int J Clin Oncol (2005) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
A ne method for studying gut transit times using radioopaque markers. Gut (1969) 8.97
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet (2001) 7.27
Persistent pain and faecal urgency after stapled haemorrhoidectomy. Lancet (2000) 7.09
Variation of bowel habit in two population samples. Br Med J (1965) 5.78
Anal-sphincter disruption during vaginal delivery. N Engl J Med (1993) 5.74
Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature (1996) 5.44
Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine. Gut (2004) 3.80
Prospective comparison of faecal incontinence grading systems. Gut (1999) 3.48
Factors affecting the outcome of endoscopic surveillance for cancer in ulcerative colitis. Gastroenterology (1994) 3.44
Prognosis after resection of chronic regional ileitis. Gut (1967) 3.27
Clinical and pathological differentiation of Crohn's disease and proctocolitis. Gastroenterology (1968) 3.20
Anismus in chronic constipation. Dig Dis Sci (1985) 3.16
Experience in the treatment of Crohn's disease of the large intestine. Gut (1966) 3.14
Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Gut (2004) 3.01
Mycobacteria as a possible cause of inflammatory bowel disease. Lancet (1978) 2.94
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. Am J Hum Genet (1999) 2.88
Third degree obstetric anal sphincter tears: risk factors and outcome of primary repair. BMJ (1994) 2.75
A comparison of oral prednisolone given as single or multiple daily doses for active proctocolitis. Scand J Gastroenterol (1978) 2.73
Cancer surveillance in ulcerative colitis. Experience over 15 years. Lancet (1983) 2.67
Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Genome Res (2001) 2.66
Cancer in colitis: assessment of the individual risk by clinical and histological criteria. Gastroenterology (1977) 2.61
The results of surgical treatment for carcinoma of the rectum of St Mark's Hospital from 1948 to 1972. Br J Surg (1976) 2.59
Jejunal efflux in short bowel syndrome. Lancet (1990) 2.52
Severe chronic constipation of young women: 'idiopathic slow transit constipation'. Gut (1986) 2.45
Childhood leukaemia and non-Hodgkin's lymphoma near large rural construction sites, with a comparison with Sellafield nuclear site. BMJ (1995) 2.41
Double-blind withdrawal trial of azathioprine as maintenance treatment for Crohn's disease. Lancet (1978) 2.40
Randomised controlled trial of CDP571 antibody to tumour necrosis factor-alpha in Crohn's disease. Lancet (1997) 2.38
Modulation of human dendritic cell phenotype and function by probiotic bacteria. Gut (2004) 2.29
Constipation: definition and classification. Postgrad Med J (1968) 2.27
Numerical taxonomy and discriminant analysis applied to non-specific colitis. Q J Med (1973) 2.26
Adalimumab for the treatment of fistulas in patients with Crohn's disease. Gut (2009) 2.20
Measurement of tryptic activity in intestinal juice as a diagnostic test of pancreatic disease. Gut (1967) 2.17
AGA technical review on anorectal testing techniques. Gastroenterology (1999) 2.05
Career prospects in medical gastroenterology in the UK: a follow up survey 1980-2. Gut (1983) 2.04
Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience. Gut (1993) 2.01
Diagnosis and treatment of chronic constipation--a European perspective. Neurogastroenterol Motil (2011) 1.99
Precancer and cancer in extensive ulcerative colitis: findings among 401 patients over 22 years. Gut (1990) 1.99
Clinical outcome of the first ten years of ulcerative colitis and proctitis. Lancet (1978) 1.99
Crohn's disease of the colon and its distinction from diverticulitis. Gut (1968) 1.95
Randomised controlled trial of azathioprine withdrawal in ulcerative colitis. BMJ (1992) 1.94
Correlations between defined sigmoidoscopic appearances and other measures of disease activity in ulcerative colitis. Dig Dis Sci (1982) 1.85
Systematic review of sacral nerve stimulation for faecal incontinence and constipation. Br J Surg (2004) 1.84
The dendritic cell: its role in intestinal inflammation and relationship with gut bacteria. Gut (2003) 1.84
Outcome of colectomy for severe idiopathic constipation. Gut (1988) 1.82
Dysplasia and deoxyribonucleic acid aneuploidy in the assessment of precancerous changes in chronic ulcerative colitis. Observer variation and correlations. Gastroenterology (1988) 1.81
Long-term clinical outcome of surgery for solitary rectal ulcer syndrome. Br J Surg (1998) 1.80
Pilot study of two new injectable bulking agents for the treatment of faecal incontinence. Colorectal Dis (2007) 1.78
Mechanisms of action of probiotics: recent advances. Inflamm Bowel Dis (2009) 1.75
Permanent sacral nerve stimulation for treatment of idiopathic constipation. Br J Surg (2002) 1.75
Controlled trial of azathioprine in chronic ulcerative colitis. Br Med J (Clin Res Ed) (1982) 1.75
Response to a behavioural treatment, biofeedback, in constipated patients is associated with improved gut transit and autonomic innervation. Gut (2001) 1.75
Bowel dysfunction in spinal-cord-injury patients. Lancet (1996) 1.74
Evaluation of Helicobacter species in inflammatory bowel disease. Aliment Pharmacol Ther (2003) 1.73
Long-term results of overlapping anterior anal-sphincter repair for obstetric trauma. Lancet (2000) 1.72
Ulcerative colitis treated by ileostomy and excisional surgery. Fifteen years' experience at St. Mark's Hospital. Br J Surg (1972) 1.71
Faecal stasis in proctocolitis. Gut (1962) 1.71
Clinical characteristics of chronic idiopathic intestinal pseudo-obstruction in adults. Gut (1997) 1.71
Radioisotope determination of regional colonic transit in severe constipation: comparison with radio opaque markers. Gut (1993) 1.71
Towards a radiologic definition of idiopathic megacolon. Gastrointest Radiol (1985) 1.69
Ileostomy and excisional surgery for chronic inflammatory disease of the colon: a survey of one hospital region. Gut (1971) 1.69
Antibodies to tumour necrosis factor alpha as treatment for Crohn's disease. Lancet (2000) 1.69
Potential candidates for small bowel transplantation. Br J Surg (1992) 1.69
Colonoscopic diagnosis of minimal change colitis in patients with a normal sigmoidoscopy and normal air-contrast barium enema. Lancet (1982) 1.68
Sexual problems among married ileostomists. Survey conducted by The Ileostomy Association of Great Britain and Ireland. Gut (1977) 1.67
Haemorrhoids: pathology, pathophysiology and aetiology. Br J Surg (1994) 1.67
Failure of rectal expulsion as a cause of constipation: why fibre and laxatives sometimes fail. Lancet (1986) 1.65
Team approach to long-term intravenous feeding in patients with gastrointestinal disorders. Lancet (1978) 1.65
Biliary tract carcinoma associated with ulcerative colitis. Q J Med (1974) 1.65
Corticosteroids and corticotrophin in the treatment of Crohn's disease. Gut (1966) 1.64
Rectal mucosal electrosensory testing--evidence for a rectal sensory neuropathy in idiopathic constipation. Dis Colon Rectum (1990) 1.64
Migration and maturation of human colonic dendritic cells. J Immunol (2001) 1.64
The burden of constipation on quality of life: results of a multinational survey. Aliment Pharmacol Ther (2007) 1.64
Total excision or restorative resection for carcinoma of the middle third of the rectum. Br J Surg (1979) 1.63
Cancer surveillance in longstanding ulcerative colitis: endoscopic appearances help predict cancer risk. Gut (2004) 1.63
Cancer of the rectum following colectomy and ileorectal anastomosis for ulcerative colitis. Br J Surg (1978) 1.62
Randomized controlled trial of topical phenylephrine in the treatment of faecal incontinence. Br J Surg (2000) 1.61
Gastrointestinal hormones in short bowel syndrome. Peptide YY may be the 'colonic brake' to gastric emptying. Gut (1996) 1.60
The treatment of early colorectal cancer by local excision. Br J Surg (1978) 1.58
Results of surgery for inflammatory bowel disease: a further survey of one hospital region. Br Med J (1974) 1.58
Results of colectomy for severe idiopathic constipation in women (Arbuthnot Lane's disease). Br J Surg (1984) 1.58
Linkage of inflammatory bowel disease to human chromosome 6p. Am J Hum Genet (1999) 1.57
An engineered human antibody to TNF (CDP571) for active Crohn's disease: a randomized double-blind placebo-controlled trial. Gastroenterology (2001) 1.57
'Reversible chemical sphincterotomy' by local application of glyceryl trinitrate. Br J Surg (1994) 1.55
Some Factors in the Assessment of Gastric Antisecretory Drugs by a Sampling Technique. Gut (1960) 1.54
Balloon expulsion from the rectum in constipation of different types. Gut (1985) 1.51
Long-term parenteral nutrition: problems with venous access. J R Soc Med (1990) 1.51
Crohn's disease: natural history and treatment. Postgrad Med J (1968) 1.51
Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study. Gut (2005) 1.49
A multinational survey of prevalence and patterns of laxative use among adults with self-defined constipation. Aliment Pharmacol Ther (2008) 1.49
Solitary rectal ulcer syndrome. Br J Surg (1998) 1.48