Published in J Lab Clin Med on November 01, 1969
Purification of IMP:pyrophosphate phosphoribosyltransferases, catalytically incompetent enzymes in Lesch-Nyhan disease. Proc Natl Acad Sci U S A (1971) 1.36
Evidence for transfer of enzyme product as the basis of metabolic cooperation between tissue culture fibroblasts of Lesch-Nyhan disease and normal cells. Proc Natl Acad Sci U S A (1970) 1.27
Hypoxanthine-guanine phosphoribosyltransferase: characteristics of the mutant enzyme in erythrocytes from patients with the Lesch-Nyhan syndrome. J Clin Invest (1972) 1.21
Variant human phosphoribosylpyrophosphate synthetase altered in regulatory and catalytic functions. J Clin Invest (1980) 1.04
Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction. J Clin Invest (1976) 1.00
Disparate enzyme activity in erythocytes and leukocytes. A variant of hypoxanthine phosphoribosyl-transferase deficiency with an unstable enzyme. J Clin Invest (1973) 0.99
Studies on the coordinate activity and liability of orotidylate phosphoribosyltransferase and decarboxylase in human erythrocytes, and the effects of allopurinol administration. J Clin Invest (1971) 0.94
Hypoxanthine phosphoribosyltransferase activity in intact fibroblasts from patients with X-linked hyperuricemia. J Clin Invest (1976) 0.91
Inosinic acid dehydrogenase activity in the Lesch-Nyhan syndrome. J Clin Invest (1972) 0.87
Separation of younger red cells with improved survival in vivo: an approach to chronic transfusion therapy. Proc Natl Acad Sci U S A (1978) 0.84
Letter: Mouse fibroblasts A9 are deficient in HPRT and APRT. Am J Hum Genet (1974) 0.81
Protein phosphorylation. Annu Rev Biochem (1975) 6.71
Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells. J Biol Chem (1978) 4.93
Familial dysautonomia: diagnosis, pathogenesis and management. Adv Pediatr (1974) 2.60
The occurrence of new mutants in the X-linked recessive Lesch-Nyhan disease. Am J Hum Genet (1976) 2.51
A micromethod for free erythrocyte porphyrins: the FEP test. J Lab Clin Med (1973) 2.44
Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta. Proc Natl Acad Sci U S A (1982) 2.40
Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol (1980) 2.30
Population genetics of haemoglobin variants, thalassaemia and glucose-6-phosphate dehydrogenase deficiency, with particular reference to the malaria hypothesis. Bull World Health Organ (1966) 2.30
Acquisition of increased hormone sensitivity during in vitro adipocyte development. J Biol Chem (1977) 2.23
Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes. J Biol Chem (1988) 2.04
Molecular forms and subunit composition of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase purified from bovine heart muscle. J Biol Chem (1972) 1.99
Transfer across the perfused human placenta of antipyrine, sodium and leucine. Am J Obstet Gynecol (1972) 1.98
Separation of erythrocytes according to age on a simplified density gradient. J Lab Clin Med (1974) 1.89
Quantitative studies of dorsal root ganglia and neuropathologic observations on spinal cords in familial dysautonomia. J Neurol Sci (1978) 1.87
Failure to detect linkage between Xg and other X-borne loci in Sardinians. Ann Hum Genet (1966) 1.82
Neonatal meningitis. A clinical and pathological study of 29 cases. Pediatrics (1966) 1.82
Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranes. J Biol Chem (1972) 1.80
In vivo lability of glucose-6-phosphate dehydrogenase in GdA- and GdMediterranean deficiency. J Clin Invest (1968) 1.72
Threshold for lead damage to heme synthesis in urban children. Proc Natl Acad Sci U S A (1982) 1.68
Familial hyperlysinemia with lysine-ketoglutarate reductase insufficiency. J Clin Invest (1969) 1.65
Inhibition of DNA synthesis by hydroxyurea: structure-activity relationships. Cancer Res (1967) 1.60
Conversion of lysine to saccharopine by human tissues. Biochim Biophys Acta (1968) 1.58
Communication between normal and enzyme deficient cells in tissue culture. Exp Cell Res (1972) 1.57
Purification and properties of the human placental insulin receptor. J Biol Chem (1981) 1.57
Pallid breath-holding spells. Evaluation of the autonomic nervous system. Clin Pediatr (Phila) (1990) 1.56
Fetal homeostasis in maternal malnutrition: potassium and sodium deficiency in rats. Pediatr Res (1970) 1.54
Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6. Proc Natl Acad Sci U S A (1980) 1.53
Further studies of hyperlysinemia. Am J Dis Child (1966) 1.52
Erythrocyte adenosine deaminase deficiency without immunodeficiency. Evidence for an unstable mutant enzyme. J Clin Invest (1979) 1.50
Identification of the cDNA for human red blood cell-specific hexokinase isozyme. Blood (1997) 1.50
Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells. J Biol Chem (1995) 1.47
Chemotherapy for induction of remission of childhood acute myeloid leukemia followed by marrow transplantation or multiagent chemotherapy: a report from the Childrens Cancer Group. J Clin Oncol (1994) 1.45
An isozyme of hexokinase specific for the human red blood cell (HKR) Blood (1990) 1.45
Insulin-stimulated protein phosphorylation in 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1979) 1.41
Cerebral hyperemia, stroke, and transfusion in sickle cell disease. Neurology (1989) 1.40
Transfer of cocaine by the perfused human placenta: the effect of binding to serum proteins. Am J Obstet Gynecol (1993) 1.39
Absence of mosaicism in the lymphocyte in X-linked congenital hyperuricosuria. Life Sci (1968) 1.38
Purification of IMP:pyrophosphate phosphoribosyltransferases, catalytically incompetent enzymes in Lesch-Nyhan disease. Proc Natl Acad Sci U S A (1971) 1.36
High affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II-B. Cloning, characterization, and expression of cDNAs for rat brain P150. J Biol Chem (1989) 1.36
Cyclic AMP-dependent protein kinase from bovine heart muscle. Methods Enzymol (1974) 1.35
The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression. J Biol Chem (1993) 1.35
Transfer of zidovudine (AZT) by human placenta. J Infect Dis (1990) 1.35
Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A. J Biol Chem (1999) 1.34
The FEP (free erythrocyte porphyrins) test: a screening micromethod for lead poisoning. Pediatrics (1973) 1.31
Trophic functions of the neuron. V. Familial dysautonomis. Current concepts of dysautonomia: neuropathological defects. Ann N Y Acad Sci (1974) 1.31
Role of murine tumor models in cancer treatment research. Cancer Res (1986) 1.30
Studies on the orientation of cyclic AMP-dependent protein kinase in human erythrocyte membranes. Proc Natl Acad Sci U S A (1973) 1.29
The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channels in neurons. J Biol Chem (1999) 1.29
Molecular characterization of an anchor protein (AKAPCE) that binds the RI subunit (RCE) of type I protein kinase A from Caenorhabditis elegans. J Biol Chem (1998) 1.28
The mechanism of red cell aging. I. Relationship between cell age and specific gravity evaluated by ultracentrifugation in a discontinuous density gradient. J Lab Clin Med (1967) 1.28
Evidence for transfer of enzyme product as the basis of metabolic cooperation between tissue culture fibroblasts of Lesch-Nyhan disease and normal cells. Proc Natl Acad Sci U S A (1970) 1.27
Changes in enzyme levels accompanying differentiation of intestinal epithelial cells. Exp Cell Res (1969) 1.27
Characterization of distinct tethering and intracellular targeting domains in AKAP75, a protein that links cAMP-dependent protein kinase II beta to the cytoskeleton. J Biol Chem (1993) 1.26
Transcranial Doppler measurements of the middle cerebral artery. Effect of hematocrit. Stroke (1988) 1.24
Development of hormone receptors and hormone responsiveness in vitro. Effect of prolonged insulin treatment on hexose uptake in 3T3-L1 adipocytes. J Biol Chem (1978) 1.23
Saccharopine cleavage by a dehydrogenase of human liver. Biochim Biophys Acta (1970) 1.22
Complementation analysis of maple syrup urine disease in heterokaryons derived from cultured human fibroblasts. Nature (1973) 1.21
Tunicamycin-mediated depletion of insulin receptors in 3T3-L1 adipocytes. J Cell Physiol (1979) 1.19
cAMP signaling in neurons: patterns of neuronal expression and intracellular localization for a novel protein, AKAP 150, that anchors the regulatory subunit of cAMP-dependent protein kinase II beta. Mol Biol Cell (1992) 1.19
Detection of Tay-Sachs disease heterozygotes by assay of hexosaminidase A in serum and leukocytes. J Pediatr (1971) 1.18
Identification of a calmodulin-binding protein that co-purifies with the regulatory subunit of brain protein kinase II. J Biol Chem (1984) 1.17
Management of childhood lead poisoning. J Pediatr (1984) 1.17
Detection of heterozygote in Lesch-Nyhan disease by hair-root analysis. N Engl J Med (1972) 1.17
Physical properties of a purified cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine heart muscle. J Biol Chem (1973) 1.17
Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system. Proc Natl Acad Sci U S A (1980) 1.16
Zellweger syndrome: biochemical and morphological studies on two patients treated with clofibrate. Pediatr Res (1985) 1.16
The role of cyclic AMP in the phosphorylation of proteins in human erythrocyte membranes. Biochem Biophys Res Commun (1973) 1.15
Characterization and comparison of membrane-associated and cytosolic cAMP-dependent protein kinases. Physicochemical and immunological studies on bovine cerebral cortex protein kinases. J Biol Chem (1979) 1.13
Regulation of fatty acid synthetase concentration and activity during adipocyte differentiation. Studies on 3T3-L1 cells. J Biol Chem (1980) 1.13
Blood lead concentrations in a remote Himalayan population. Science (1980) 1.13
Molecular characterization of a cDNA that encodes six isoforms of a novel murine A kinase anchor protein. J Biol Chem (1998) 1.13
Recent studies of the 3T3-L1 adipocyte-like cell line. Recent Prog Horm Res (1979) 1.12
Familial dysautonomia. N Engl J Med (1966) 1.12
Absence of acid maltase in glycogenesis type 2(Pompe's disease) in tissue culture. Am J Dis Child (1969) 1.12
Neurologic outcome after electroencephalographically proven neonatal seizures. Pediatrics (1991) 1.11
Latent insulin receptors and possible receptor precursors in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (1983) 1.11
Assembly of AKAP82, a protein kinase A anchor protein, into the fibrous sheath of mouse sperm. Dev Biol (1997) 1.11
Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells. J Biol Chem (1996) 1.11
Intermittent branched-chain ketonuria. Variant of maple-syrup-urine disease. N Engl J Med (1967) 1.11
Erythropoietic protoporphyria and lead intoxication: the molecular basis for difference in cutaneous photosensitivity. II. Different binding of erythrocyte protoporphyrin to hemoglobin. J Clin Invest (1975) 1.10
Structure and expression of novel spliced leader RNA genes in Caenorhabditis elegans. J Biol Chem (1995) 1.10
Multiple enzyme defects in familial hyperlysinemia. Pediatr Res (1976) 1.09
Serum follicle-stimulating hormone and luteinizing hormone levels in women aged 35-60 in the U.S. population: the Third National Health and Nutrition Examination Survey (NHANES III, 1988-1994). Menopause (1999) 1.09
Enzyme activity in classical and variant forms of maple syrup urine disease. J Pediatr (1972) 1.08
Erythropoietic protoporphyria and lead intoxication: the molecular basis for difference in cutaneous photosensitivity. I. Different rates of disappearance of protoporphyrin from the erythrocytes, both in vivo and in vitro. J Clin Invest (1975) 1.08
A normal level of adenosine deaminase activity in the red cell lysates of carriers and patients with severe combined immunodeficiency disease. Proc Natl Acad Sci U S A (1976) 1.07
Patient care, resident stress, and government regulation. Am J Dis Child (1989) 1.06
The sural nerve in familial dysautonomia. J Neuropathol Exp Neurol (1975) 1.06
Metabolic cooperation in cell culture: studies of the mechanisms of cell interaction. J Cell Physiol (1974) 1.06
Cloning and expression of an intron-less gene for AKAP 75, an anchor protein for the regulatory subunit of cAMP-dependent protein kinase II beta. J Biol Chem (1992) 1.05