Published in J Biol Chem on May 25, 1977
TXNIP regulates peripheral glucose metabolism in humans. PLoS Med (2007) 3.27
Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein. Proc Natl Acad Sci U S A (1984) 2.98
Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone. J Cell Biol (1988) 2.73
Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol (1980) 2.30
The interaction of thioredoxin with Txnip. Evidence for formation of a mixed disulfide by disulfide exchange. J Biol Chem (2006) 2.15
Minireview: Pref-1: role in adipogenesis and mesenchymal cell fate. Mol Endocrinol (2009) 2.03
Alterations in insulin binding accompanying differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1977) 2.01
The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages. Mol Endocrinol (2008) 2.00
A study of the adipose conversion of suspended 3T3 cells by using glycerophosphate dehydrogenase as differentiation marker. Proc Natl Acad Sci U S A (1979) 1.94
Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1980) 1.82
Adipose conversion of 3T3 cells depends on a serum factor. Proc Natl Acad Sci U S A (1978) 1.82
Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance. Proc Natl Acad Sci U S A (2007) 1.79
A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. Mol Cell Biol (1998) 1.60
A developmentally regulated mRNA from 3T3 adipocytes encodes a novel serine protease homologue. Proc Natl Acad Sci U S A (1985) 1.55
Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6. Proc Natl Acad Sci U S A (1980) 1.53
APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes. Mol Cell Biol (2002) 1.52
Control of adipocyte differentiation. Biochem J (1995) 1.48
Establishment of preadipocyte clonal line from epididymal fat pad of ob/ob mouse that responds to insulin and to lipolytic hormones. Proc Natl Acad Sci U S A (1978) 1.43
Insulin-stimulated protein phosphorylation in 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1979) 1.41
Expression of the differentiation-induced gene for fatty acid-binding protein is activated by glucocorticoid and cAMP. Proc Natl Acad Sci U S A (1988) 1.40
Insulin stimulates the tyrosine phosphorylation of caveolin. J Cell Biol (1995) 1.35
Adipsin, the adipocyte serine protease: gene structure and control of expression by tumor necrosis factor. Nucleic Acids Res (1986) 1.34
Insulin and growth factor effects on c-fos expression in normal and protein kinase C-deficient 3T3-L1 fibroblasts and adipocytes. Proc Natl Acad Sci U S A (1986) 1.31
Hormone-sensitive lipase in differentiated 3T3-L1 cells and its activation by cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A (1981) 1.29
Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene. Proc Natl Acad Sci U S A (1998) 1.17
Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes. Biochem J (1997) 1.16
Adipogenic and anti-adipogenic factors in the pituitary and other organs. Proc Natl Acad Sci U S A (1981) 1.04
Desensitization of the insulin receptor at an early postreceptor step by prolonged exposure to antireceptor antibody. Proc Natl Acad Sci U S A (1979) 1.01
3T3 fibroblasts transfected with a cDNA for mitochondrial aspartate aminotransferase express plasma membrane fatty acid-binding protein and saturable fatty acid uptake. Proc Natl Acad Sci U S A (1995) 1.00
Increase in fatty acid synthetase content of 3T3-L cells undergoing spontaneous and chemically induced differentiation to adipocytes. Biochem J (1979) 0.96
Transcriptional down-regulation by insulin of the beta 3-adrenergic receptor expression in 3T3-F442A adipocytes: a mechanism for repressing the cAMP signaling pathway. Proc Natl Acad Sci U S A (1994) 0.95
Cloning and characterization of Cbl-associated protein splicing isoforms. Mol Med (2003) 0.86
Cyclic AMP effects on cell-to-cell junctional membrane permeability during adipocyte differentiation of 3T3-L1 fibroblasts. J Cell Biol (1985) 0.85
Convenient and rapid removal of detergent from glycolipids in detergent-resistant membrane microdomains. J Lipid Res (2012) 0.81
Targeted inactivation of the insulin receptor gene in mouse 3T3-L1 fibroblasts via homologous recombination. Proc Natl Acad Sci U S A (1991) 0.80
Studying lipolysis in adipocytes by combining siRNA knockdown and adenovirus-mediated overexpression approaches. Methods Cell Biol (2013) 0.79
Insulin and serum increase the number of receptors for vasopressin in a kidney-derived line of cells grown in a defined medium. Proc Natl Acad Sci U S A (1980) 0.79
Induction of glucagon sensitivity in a transformed kidney cell line by prostaglandin E2 and its inhibition by epidermal growth factor. Mol Cell Biol (1987) 0.77
Modulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modifications. Yonsei Med J (2013) 0.77
Differentiation of 3T3-L2 fibroblasts into adipose cells in bromodeoxyuridine-suppressed cultures. Proc Natl Acad Sci U S A (1979) 0.76
3T3-L1 preadipocyte differentiation and poly(ADP-ribose) synthetase. Mol Cell Biochem (1983) 0.76
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature (1993) 7.56
Protein phosphorylation. Annu Rev Biochem (1975) 6.71
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev (1990) 6.33
Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells. J Biol Chem (1978) 4.93
Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. Proc Natl Acad Sci U S A (1986) 4.40
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. J Biol Chem (1987) 4.32
Structure, organization and polymorphism of murine and human T-cell receptor alpha and beta chain gene families. Immunol Rev (1988) 4.23
Phosphorylation activates the insulin receptor tyrosine protein kinase. Proc Natl Acad Sci U S A (1983) 3.94
After insulin binds. Science (1987) 3.16
Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2. Genes Dev (1996) 3.01
Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron (1995) 2.83
Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain. Neuron (1992) 2.79
Effect of dibutyryladenosine 3':5'-cyclic monophosphate on growth and differentiation in Caulobacter crescentus. Proc Natl Acad Sci U S A (1972) 2.73
Transcriptional control of the mouse prealbumin (transthyretin) gene: both promoter sequences and a distinct enhancer are cell specific. Mol Cell Biol (1986) 2.43
Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta. Proc Natl Acad Sci U S A (1982) 2.40
Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study. Diabetologia (2009) 2.32
Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol (1980) 2.30
Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family. Proc Natl Acad Sci U S A (1993) 2.27
Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate. J Biol Chem (1985) 2.15
Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease. Genomics (1989) 2.10
Insulin-like growth factor-I is an essential regulator of the differentiation of 3T3-L1 adipocytes. J Biol Chem (1988) 2.04
The extent of linkage disequilibrium in four populations with distinct demographic histories. Am J Hum Genet (2000) 2.03
The cell-specific enhancer of the mouse transthyretin (prealbumin) gene binds a common factor at one site and a liver-specific factor(s) at two other sites. Mol Cell Biol (1988) 2.03
Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein. Mol Cell Biol (1992) 2.01
Molecular forms and subunit composition of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase purified from bovine heart muscle. J Biol Chem (1972) 1.99
Glucose transporters serve as water channels. Proc Natl Acad Sci U S A (1990) 1.95
Activation of S6 kinase activity in 3T3-L1 cells by insulin and phorbol ester. Proc Natl Acad Sci U S A (1985) 1.89
Glucose deprivation and hexose transporter polypeptides of murine fibroblasts. J Biol Chem (1986) 1.81
Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranes. J Biol Chem (1972) 1.80
Flow cytometric platform for high-throughput single nucleotide polymorphism analysis. Biotechniques (2001) 1.75
Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and catabolite repression. Proc Natl Acad Sci U S A (1974) 1.71
Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription. Science (1987) 1.70
The distribution of total and specific serum IgE in the European Community Respiratory Health Survey. J Allergy Clin Immunol (1997) 1.61
Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6. Proc Natl Acad Sci U S A (1983) 1.59
Description of a protein kinase derived from insulin-treated 3T3-L1 cells that catalyzes the phosphorylation of ribosomal protein S6 and casein. J Biol Chem (1983) 1.59
Purification and properties of the human placental insulin receptor. J Biol Chem (1981) 1.57
Myelin deficient mice: expression of myelin basic protein and generation of mice with varying levels of myelin. Cell (1987) 1.55
Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation. J Biol Chem (1986) 1.54
Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6. Proc Natl Acad Sci U S A (1980) 1.53
Growth factors rapidly induce expression of the glucose transporter gene. J Biol Chem (1988) 1.53
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation. J Biol Chem (1987) 1.52
Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta. Proc Natl Acad Sci U S A (1984) 1.49
Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells. J Biol Chem (1995) 1.47
Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina. J Neurobiol (1994) 1.43
Optimized conditions for pulsed field gel electrophoretic separations of DNA. Nucleic Acids Res (1988) 1.43
A novel instrument for separating large DNA molecules with pulsed homogeneous electric fields. Science (1988) 1.42
Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein. J Biol Chem (1988) 1.42
Insulin-stimulated protein phosphorylation in 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1979) 1.41
Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor. J Biol Chem (1986) 1.41
Phosphorylation of a cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle. J Biol Chem (1974) 1.40
Reversible autophosphorylation of a cyclic 3':5'-AMP-dependent protein kinase from bovine cardiac muscle. J Biol Chem (1975) 1.40
Elevated AMP pyrophosphorylase activity in congenital IMP pyrophosphorylase deficiencey (Lesch-Nyhan disease). J Lab Clin Med (1969) 1.40
Soluble cyclic AMP-dependent protein kinases: review of the enzyme isolated from bovine cardiac muscle. Curr Top Cell Regul (1977) 1.37
Purification of IMP:pyrophosphate phosphoribosyltransferases, catalytically incompetent enzymes in Lesch-Nyhan disease. Proc Natl Acad Sci U S A (1971) 1.36
High affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II-B. Cloning, characterization, and expression of cDNAs for rat brain P150. J Biol Chem (1989) 1.36
Cyclic AMP-dependent protein kinase from bovine heart muscle. Methods Enzymol (1974) 1.35
The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression. J Biol Chem (1993) 1.35
Regulation of cAMP-mediated signal transduction via interaction of caveolins with the catalytic subunit of protein kinase A. J Biol Chem (1999) 1.34
Pulsed field gel electrophoresis techniques for separating 1- to 50-kilobase DNA fragments. Anal Biochem (1989) 1.33
Analysis of a human V beta gene subfamily. J Exp Med (1986) 1.33
The effect of nucleotides and a nondialyzable factor on the hydrolysis of cyclic AMP by a cyclic nucleotide phosphodiesterase from beef heart. Arch Biochem Biophys (1971) 1.32
The winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcription. Mol Cell Biol (2001) 1.32
Studies on the orientation of cyclic AMP-dependent protein kinase in human erythrocyte membranes. Proc Natl Acad Sci U S A (1973) 1.29
The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channels in neurons. J Biol Chem (1999) 1.29
Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid. J Biol Chem (1988) 1.29
Molecular characterization of an anchor protein (AKAPCE) that binds the RI subunit (RCE) of type I protein kinase A from Caenorhabditis elegans. J Biol Chem (1998) 1.28
Dissociation and reassociation of the phosphorylated and nonphosphorylated forms of adenosine 3':5' -monophosphate-dependent protein kinase from bovine cardiac muscle. J Biol Chem (1976) 1.28
Phosphorylation of exogenous substrates by the insulin receptor-associated protein kinase. J Biol Chem (1983) 1.28
Characterization of distinct tethering and intracellular targeting domains in AKAP75, a protein that links cAMP-dependent protein kinase II beta to the cytoskeleton. J Biol Chem (1993) 1.26
Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product. J Biol Chem (1987) 1.26
Purification and properties of a specific fructose 1,6-diphosphatase from Candida utilis. Arch Biochem Biophys (1965) 1.25
Properties of an adenyl cyclase partially purified from frog erythrocytes. Arch Biochem Biophys (1969) 1.24
Dual role of brain factor-1 in regulating growth and patterning of the cerebral hemispheres. Cereb Cortex (1999) 1.23
Development of hormone receptors and hormone responsiveness in vitro. Effect of prolonged insulin treatment on hexose uptake in 3T3-L1 adipocytes. J Biol Chem (1978) 1.23
Biosynthetic precursors and in vitro translation products of the glucose transporter of human hepatocarcinoma cells, human fibroblasts, and murine preadipocytes. J Biol Chem (1985) 1.22
FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals. Mol Cell Biol (1999) 1.20
Interconversion of cyclic nucleotide-activated and cyclic nucleotide-independent forms of a protein kinase from beef heart. Proc Natl Acad Sci U S A (1971) 1.20
Tunicamycin-mediated depletion of insulin receptors in 3T3-L1 adipocytes. J Cell Physiol (1979) 1.19
Gene structure and chromosomal localization of the human P2X7 receptor. Receptors Channels (1998) 1.19
cAMP signaling in neurons: patterns of neuronal expression and intracellular localization for a novel protein, AKAP 150, that anchors the regulatory subunit of cAMP-dependent protein kinase II beta. Mol Biol Cell (1992) 1.19
Identification of a calmodulin-binding protein that co-purifies with the regulatory subunit of brain protein kinase II. J Biol Chem (1984) 1.17
Effects of an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, MK-0916, in patients with type 2 diabetes mellitus and metabolic syndrome. Diabetes Obes Metab (2011) 1.17
Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivo. J Biol Chem (1986) 1.17
Physical properties of a purified cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine heart muscle. J Biol Chem (1973) 1.17