Published in J Clin Invest on April 01, 1970
Therapeutic antibodies for autoimmunity and inflammation. Nat Rev Immunol (2010) 4.21
Antibody-based protection against HIV infection by vectored immunoprophylaxis. Nature (2011) 3.80
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat. J Clin Invest (1972) 2.88
IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life. Malar J (2007) 2.30
Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific. Infect Immun (2008) 2.18
Mouse/human chimeric monoclonal antibody in man: kinetics and immune response. Proc Natl Acad Sci U S A (1989) 2.15
The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections. PLoS Pathog (2010) 2.03
Imbalances of gamma globulin subgroups and gene defects in patients with primary hypogammaglobulinemia. J Clin Invest (1970) 1.86
Endoglin-targeted cancer therapy. Curr Drug Deliv (2011) 1.65
In vivo target-specific activatable near-infrared optical labeling of humanized monoclonal antibodies. Mol Cancer Ther (2009) 1.55
Maternal vaccination: moving the science forward. Hum Reprod Update (2014) 1.50
Fc-fusion proteins: new developments and future perspectives. EMBO Mol Med (2012) 1.44
Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination. PLoS Pathog (2016) 1.43
Advances in human B cell phenotypic profiling. Front Immunol (2012) 1.41
Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax. Infect Immun (2007) 1.40
CTLA-4 blockade: therapeutic potential in cancer treatments. Onco Targets Ther (2010) 1.33
Hypogammaglobulinemia associated with accelerated catabolism of IgG secondary to its inteaction with an IgG-reactive monoclonal IgM. J Clin Invest (1971) 1.29
Immunoglobulin G3 from polyclonal human immunodeficiency virus (HIV) immune globulin is more potent than other subclasses in neutralizing HIV type 1. J Virol (2001) 1.29
Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow. Immunity (2015) 1.27
Metabolic properties of human IgA subclasses. Clin Exp Immunol (1973) 1.26
HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life. Mucosal Immunol (2013) 1.23
A Temporal Model of Human IgE and IgG Antibody Function. Front Immunol (2013) 1.23
What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity. Malar J (2009) 1.18
Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid. J Exp Med (2010) 1.15
Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential. Nat Commun (2011) 1.11
The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics. J Clin Invest (1997) 1.03
Metabolism of autologous and homologous IgG in rheumatoid arthritis. J Clin Invest (1977) 1.01
The catabolism of human G immunoglobulins of different heavy chain subclasses. 3. The catabolism of heavy chain disease proteins and of Fc fragments of myeloma proteins. Clin Exp Immunol (1972) 0.99
Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy. Cell (2015) 0.99
Porphyromonas gingivalis-specific serum IgG and IgA antibodies originate from immunoglobulin-secreting cells in inflamed gingiva. Clin Exp Immunol (1991) 0.96
Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection. Eur J Immunol (2014) 0.96
Qualitative and quantitative studies on IgG2 globulins in individual human sera with an antiserum capable of differentiating between Gm(n+) and Gm(n-) proteins. Clin Exp Immunol (1973) 0.95
Transplacental transmission of serotype-specific pneumococcal antibodies in a Brazilian population. Clin Diagn Lab Immunol (1999) 0.94
Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication. AIDS Res Hum Retroviruses (2015) 0.94
Compartmental tissue distribution of antibody therapeutics: experimental approaches and interpretations. AAPS J (2012) 0.92
The relationship between L-chain synthesis and gamma-globulin production. J Clin Invest (1973) 0.92
IgG3 levels in patients with chronic membranoproliferative glomerulonephritis. Br Med J (1972) 0.92
Metabolism of radio-iodinated IgG in patients with abnormal IgG levels. I. Hypergamma-globulinaemia. Clin Exp Immunol (1971) 0.91
Enhanced serum levels of soluble HLA class I molecules are induced by treatment with recombinant interferon-gamma (IFN-gamma). Clin Exp Immunol (1991) 0.90
Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life. J Biol Chem (2012) 0.90
Human IgG subclasses: in vitro neutralization of and in vivo protection against West Nile virus. J Virol (2010) 0.90
Linking influenza virus tissue tropism to population-level reproductive fitness. PLoS One (2012) 0.90
Immunoglobulin G3 subclass production by rheumatoid synovial tissue cultures. J Clin Invest (1982) 0.89
Simulation of B cell affinity maturation explains enhanced antibody cross-reactivity induced by the polyvalent malaria vaccine AMA1. J Immunol (2014) 0.89
Predicting the F(ab)-mediated effect of monoclonal antibodies in vivo by combining cell-level kinetic and pharmacokinetic modelling. J Pharmacokinet Pharmacodyn (2012) 0.88
Population pharmacokinetics of sibrotuzumab, a novel therapeutic monoclonal antibody, in cancer patients. Invest New Drugs (2004) 0.88
Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3). Mol Cell Proteomics (2015) 0.88
Explaining observed infection and antibody age-profiles in populations with urogenital schistosomiasis. PLoS Comput Biol (2011) 0.87
Human fibronectin metabolism. J Clin Invest (1985) 0.86
IgG1 thioether bond formation in vivo. J Biol Chem (2013) 0.86
Defective generation of alloreactive cytotoxic T lymphocytes (CTL) in human monoclonal gammopathies. Clin Exp Immunol (1988) 0.86
Antibody responses during hepatitis B viral infection. PLoS Comput Biol (2014) 0.86
Anti-Tac-H, a humanized antibody to the interleukin 2 receptor, prolongs primate cardiac allograft survival. Proc Natl Acad Sci U S A (1991) 0.85
Population pharmacokinetics of antifibroblast activation protein monoclonal antibody F19 in cancer patients. Br J Clin Pharmacol (2001) 0.85
Engineering a monomeric Fc domain modality by N-glycosylation for the half-life extension of biotherapeutics. J Biol Chem (2013) 0.84
Using the Lessons Learned From the Clinic to Improve the Preclinical Development of Antibody Drug Conjugates. Pharm Res (2014) 0.84
Phagocytic, opsonic and immunoglobulin studies in newborns. Calif Med (1973) 0.84
Myelin basic protein autoantibodies, white matter disease and stroke outcome. J Neuroimmunol (2012) 0.83
Plasma half-lives and bioavailability of human monoclonal Rh D antibodies BRAD-3 and BRAD-5 following intramuscular injection into Rh D-negative volunteers. Clin Exp Immunol (1994) 0.83
Omalizumab: a monoclonal anti-IgE antibody. MedGenMed (2005) 0.82
Subclass responses and their half-lives for antibodies against EBA175 and PfRh2 in naturally acquired immunity against Plasmodium falciparum malaria. Malar J (2014) 0.82
Immunoglobulins in myasthenia gravis. Kinetic properties of the acetylcholine-receptor antibody studied during lymph drainage. Clin Exp Immunol (1978) 0.82
Rapid polyclonal desensitization with antibodies to IgE and FcεRIα. J Allergy Clin Immunol (2013) 0.82
Increased half-life of gammaglobulin after prolonged intravenous replacement therapy. Clin Exp Immunol (1987) 0.81
Population pharmacokinetic data analysis of three phase I studies of matuzumab, a humanised anti-EGFR monoclonal antibody in clinical cancer development. Br J Cancer (2008) 0.81
In vivo metabolism of a monoclonal IgG cryoglobulin. Clin Exp Immunol (1979) 0.81
Quantitative abnormalities of allotypic genes in families with primary immune deficiencies. Proc Natl Acad Sci U S A (1972) 0.81
Negative conversion of high serum p53 antibody titers in a patient with gastric cancer at 31 months after surgery. Clin J Gastroenterol (2017) 0.81
Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus. Lupus Sci Med (2016) 0.79
Interaction of menstrual cycle phase and sexual activity predicts mucosal and systemic humoral immunity in healthy women. Physiol Behav (2015) 0.79
Simulation of monoclonal antibody pharmacokinetics in humans using a minimal physiologically based model. AAPS J (2014) 0.79
A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA. MAbs (2015) 0.78
Tolerability, pharmacokinetics and pharmacodynamics of CMAB007, a humanized anti-immunoglobulin E monoclonal antibody, in healthy Chinese subjects. MAbs (2012) 0.78
Behaviour of two IgG subclasses in transport of immunoglobulin across the human placenta. J Anat (1996) 0.78
Selection of nanobodies that target human neonatal Fc receptor. Sci Rep (2013) 0.78
Subclasses of IgG produced in the rheumatoid synovium. Rheumatol Int (1984) 0.77
Metabolism of radio-iodinated IgG in patients with abnormal serum IgG levels. II. Hypogamma-globulinaemia. Clin Exp Immunol (1971) 0.77
Ontogeny and distribution of Fc gamma receptors in the human placenta. Transport or immune surveillance? J Anat (1994) 0.77
Clinical and immunochemical study of the serum IgG fraction not precipitated in a zinc-sodium salicylate reagent. J Clin Pathol (1976) 0.77
Evaluation of Evolocumab (AMG 145), a Fully Human Anti-PCSK9 IgG2 Monoclonal Antibody, in Subjects With Hepatic Impairment. J Clin Pharmacol (2016) 0.76
Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis. PLoS One (2013) 0.76
Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions. J Immunol (2015) 0.76
Modeling and Validation of Multilayer Poly(Lactide-Co-Glycolide) Scaffolds for In Vitro Directed Differentiation of Juxtaposed Cartilage and Bone. Tissue Eng Part A (2015) 0.76
Neisseria meningitidis Group A IgG1 and IgG2 Subclass Immune Response in African Children Aged 12-23 Months Following Meningococcal Vaccination. Clin Infect Dis (2015) 0.76
Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting. MAbs (2015) 0.75
Multiple infusions of human intravenous immunoglobulin in chimpanzees do not lead to immune elimination. Clin Exp Immunol (1990) 0.75
Exploring the immunoproteome for ovarian cancer biomarker discovery. Int J Mol Sci (2011) 0.75
Improved Synthesis and In Vitro Evaluation of an Aptamer Ribosomal Toxin Conjugate. Nucleic Acid Ther (2016) 0.75
The Production Processes and Biological Effects of Intravenous Immunoglobulin. Biomolecules (2016) 0.75
Merozoite Antigens of Plasmodium falciparum Elicit Strain-Transcending Opsonizing Immunity. Infect Immun (2016) 0.75
Serum Concentrations of IgG4 in the Spanish Adult Population: Relationship with Age, Gender, and Atopy. PLoS One (2016) 0.75
A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties. PLoS One (2015) 0.75
Immunoglobulin profiles provide new insights into infectious diseases. Yale J Biol Med (1983) 0.75
Metabolism of IgG in type II mixed essential cryoglobulinaemia--autologous cryoprecipitated and normal homologous IgG are incorporated into complexes and metabolized in vivo at similar rates. Clin Exp Immunol (1983) 0.75
Influence of tumour burden on trastuzumab pharmacokinetics in HER2 positive non-metastatic breast cancer. Br J Clin Pharmacol (2016) 0.75
Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment. Eur J Clin Pharmacol (2015) 0.75
Immunological Changes in Blood of Newborns Exposed to Anti-TNF-α during Pregnancy. Front Immunol (2017) 0.75
Pharmacokinetics of Monoclonal Antibodies. CPT Pharmacometrics Syst Pharmacol (2017) 0.75
Disulfide Bond Characterization of Endogenous IgG3 Monoclonal Antibodies Using LC-MS: An Investigation of IgG3 Disulfide-mediated Isoforms. Anal Methods (2016) 0.75
QUANTITATIVE DETERMINATION OF SERUM IMMUNOGLOBULINS IN ANTIBODY-AGAR PLATES. J Immunol (1965) 16.97
Gamma-globulin and acquired immunity to human malaria. Nature (1961) 13.07
The theory of tracer experiments with 131I-labelled plasma proteins. Phys Med Biol (1957) 7.66
Metabolism of immunoglobulins. Prog Allergy (1969) 5.74
Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers. J Exp Med (1968) 5.72
THE CATABOLISM OF HOMOLOGOUS AND HETEROLOGOUS 7S GAMMA GLOBULIN FRAGMENTS. J Exp Med (1965) 3.87
METABOLISM OF HUMAN GAMMA MACROGLOBULINS. J Clin Invest (1964) 3.38
A THEORETICAL MODEL OF GAMMA-GLOBULIN CATABOLISM. Nature (1964) 3.31
The role of the kidney in the catabolism of Bence Jones proteins and immunoglobulin fragments. J Exp Med (1967) 3.06
Immunoglobulin changes in disease: quantitation on the basis of heavy polypeptide chains, IgG (gammaG), IgA (gammaA), and IgM (gammaM), and of light polypeptide chains, type K (I) and type L (II). J Clin Invest (1965) 3.00
Clinical and experimental metabolism of normal 6.6s gamma-globulin in normal subjects and in patients with macroglobulinemia and multiple myeloma. J Lab Clin Med (1963) 2.96
THE IMMUNOGLOBULINS OF MICE. V. THE METABOLIC (CATABOLIC) PROPERTIES OF FIVE IMMUNOGLOBULIN CLASSES. J Exp Med (1965) 2.91
Studies of the Vi (gamma-2c) subgroup of gamma-globulin. A relationship between concentration and genetic type among normal individuals. J Exp Med (1967) 2.82
FACTORS CONTROLLING SERUM GAMMA-GLOBULIN CONCENTRATION. J Exp Med (1963) 2.78
Structural studies of immunoglobulin G. Nature (1969) 2.63
Turnover of labeled normal gamma globulin in multiple myeloma. J Clin Invest (1960) 2.09
RELATIONSHIP BETWEEN GAMMA-GLOBULIN METABOLISM AND LOW SERUM GAMMA-GLOBULIN IN GERMFREE MICE. J Immunol (1964) 2.05
INFECTION, ANTIBODY RESPONSE AND GAMMA GLOBULIN COMPONENTS IN MULTIPLE MYELOMA AND MACROGLOBULINEMIA. Am J Med (1963) 1.93
Catabolism of human gammaG-immunoglobulins of different heavy chain subclasses. I. Catabolism of gammaG-myeloma proteins in man. J Clin Invest (1968) 1.71
The C-terminal sequences of the heavy chains of human immunoglobulin G myeloma proteins of differing isotopes and allotypes. Biochem J (1967) 1.58
Use of insoluble antibody for quantitative determination of small amounts of immunoglobulin. J Immunol (1969) 1.51
Catabolism and distribution of gamma-globulin. A preliminary study with 131 I-labelled gammaglobulin. Acta Med Scand (1963) 1.17
Heavy chain subclasses of human gamma G-globulin. Serum distribution and cellular localization. J Exp Med (1967) 1.13
Catabolism of human gamma-G immunoglobulins of different heavy chain subclasses. II. Catabolism of gamma-G myeloma proteins in heterologous species. J Immunol (1968) 0.97
A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells. J Immunol (1981) 10.92
A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Nature (1982) 9.42
Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia. Lancet (1974) 8.13
Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Nature (1984) 7.37
Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. N Engl J Med (1985) 6.46
Metabolism of immunoglobulins. Prog Allergy (1969) 5.74
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature (2011) 5.41
Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Proc Natl Acad Sci U S A (1984) 4.90
Clustered arrangement of immunoglobulin lambda constant region genes in man. Nature (1981) 4.87
Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex. Proc Natl Acad Sci U S A (1986) 4.61
High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood. Lancet (1981) 4.39
The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif. Proc Natl Acad Sci U S A (1989) 4.22
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Proc Natl Acad Sci U S A (1985) 3.74
Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells. Proc Natl Acad Sci U S A (1981) 3.73
Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells. Nature (1981) 3.64
The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes. Science (1986) 3.32
Expression of interleukin 2 receptors on activated human B cells. J Exp Med (1984) 3.27
Protein-losing enteropathy. Gastroenterology (1966) 3.21
Evidence for individual human peripheral blood lymphocytes bearing both B and T cell markers. Nature (1974) 3.12
The role of the kidney in the catabolism of Bence Jones proteins and immunoglobulin fragments. J Exp Med (1967) 3.06
Immunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasms. N Engl J Med (1983) 2.96
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins. J Clin Invest (1983) 2.91
Accelerated breakdown of immunoglobulin G (IgG) in myotonic dystrophy: a hereditary error of immunoglobulin catabolism. J Clin Invest (1966) 2.91
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat. J Clin Invest (1972) 2.88
IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice. Proc Natl Acad Sci U S A (2000) 2.80
The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci U S A (1994) 2.79
Characterization of the human receptor for T-cell growth factor. Proc Natl Acad Sci U S A (1983) 2.76
Variable amplification of immunoglobulin lambda light-chain genes in human populations. Nature (1983) 2.75
Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Proc Natl Acad Sci U S A (1983) 2.73
Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. J Immunol (1983) 2.65
The Wiskott-Aldrich syndrome. A disorder with a possible defect in antigen processing or recognition. Lancet (1968) 2.61
A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci U S A (1994) 2.51
Ataxia-telangiectasia. Medicine (Baltimore) (1972) 2.50
The mechanism of appearance of immunoglobulin A in nasal secretions in man. J Clin Invest (1967) 2.45
The three-dimensional structure at 6 A resolution of a human gamma Gl immunoglobulin molecule. J Biol Chem (1971) 2.38
The Sézary syndrome: a malignant proliferation of helper T cells. J Clin Invest (1976) 2.32
Passive immunotherapy of cancer in animals and man. Adv Cancer Res (1977) 2.32
IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels. Immunity (1996) 2.23
A humanized antibody that binds to the interleukin 2 receptor. Proc Natl Acad Sci U S A (1989) 2.23
Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript. Proc Natl Acad Sci U S A (1989) 2.23
The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells. Proc Natl Acad Sci U S A (1987) 2.22
Amyloidosis: its nature and pathogenesis. Semin Hematol (1973) 2.21
Separation of human blood monocytes and lymphocytes on a continuous Percoll gradient. J Immunol Methods (1980) 2.21
Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen. J Immunol (1984) 2.20
Dynamic, yet structured: The cell membrane three decades after the Singer-Nicolson model. Proc Natl Acad Sci U S A (2003) 2.20
Communications. IgD-bearing human lymphocytes. J Immunol (1972) 2.17
Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature (1998) 2.17
Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: a phase I/II clinical trial. Proc Natl Acad Sci U S A (1999) 2.14
A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin. Nature (1989) 2.13
Only high-affinity receptors for interleukin 2 mediate internalization of ligand. Proc Natl Acad Sci U S A (1986) 2.12
NIH conference. T-cell lymphoproliferative syndrome associated with human T-cell leukemia/lymphoma virus. Ann Intern Med (1984) 2.10
Systemic capillary leak syndrome and monoclonal IgG gammopathy; studies in a sixth patient and a review of the literature. Medicine (Baltimore) (1977) 2.07
T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck. Proc Natl Acad Sci U S A (1991) 2.03
Characterization of common variable immunodeficiency: identification of a subset of patients with distinctive immunophenotypic and clinical features. Blood (1990) 2.02
Novel T-lymphocyte population in combined immunodeficiency with features of graft-versus-host disease. N Engl J Med (1989) 1.99
Suppressor cells in the regulation of the immune response. Prog Clin Immunol (1977) 1.99
Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells. J Immunol (1984) 1.99
Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes. J Immunol (1987) 1.96
Correlations between the concentrations of the four sub-classes of IgG and Gm Allotypes in normal human sera. J Immunol (1972) 1.96
Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies. J Clin Oncol (2000) 1.95
Amino acid sequence of an amyloid fibril protein of unknown origin. J Biol Chem (1972) 1.90
Intestinal lymphangiectasia: a protein-losing enteropathy with hypogammaglobulinemia, lymphocytopenia and impaired homograft rejection. J Clin Invest (1967) 1.88
Polyclonal B-cell activators in the study of the regulation of immunoglobulin synthesis in the human system. Adv Immunol (1982) 1.85
Defective lymphocyte transformation and delayed hypersensitivity in Wiskott-Aldrich syndrome. J Immunol (1970) 1.85
Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells. Nature (1985) 1.85
The role of cell-surface receptors in the transport and catabolism of immunoglobulins. Ciba Found Symp (1972) 1.80
Disorders of suppressor immunoregulatory cells in the pathogenesis of immunodeficiency and autoimmunity. Ann Intern Med (1978) 1.78
Skin-sensitizing activity related to gamma- polypeptide chain characteristics of human IgG. J Immunol (1965) 1.77
Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages. J Exp Med (1975) 1.77
Characterization of the nonphagocytic adherent cell from the peritoneal cavity of normal and BCG-treated mice. J Immunol (1977) 1.77
Serum alpha-fetoprotein in patients with neoplasms of the gastrointestinal tract. Cancer Res (1975) 1.75
B-cell alloantigens determined by the H-2 linked Ir region are associated with mixed lymphocyte culture stimulation. Science (1974) 1.73
The arrangement of immunoglobulin and T cell receptor genes in human lymphoproliferative disorders. Adv Immunol (1987) 1.73
GM and INV factors in subclasses of human IgG. J Exp Med (1965) 1.72
Human monoclonal gamma G-cryoglobulins with anti-gamma-globulin activity. J Clin Invest (1968) 1.72
Elevated gamma-globulin and increased antibody production in mice infected with lactic dehydrogenase virus. J Exp Med (1966) 1.71
The renal handling of low molecular weight proteins. II. Disorders of serum protein catabolism in patients with tubular proteinuria, the nephrotic syndrome, or uremia. J Clin Invest (1972) 1.70
Disorders of immunoglobulin metabolism. N Engl J Med (1969) 1.69
Human gamma-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7. Nature (1985) 1.66
Serum-alpha-fetoprotein levels in patients with ataxia-telangiectasia. Lancet (1972) 1.66
Identification of a novel receptor/signal transduction pathway for IL-15/T in mast cells. EMBO J (1996) 1.65
Rearrangements of genes for the antigen receptor on T cells as markers of lineage and clonality in human lymphoid neoplasms. N Engl J Med (1985) 1.65
The immunoglobulin origin of amyloid. Am J Med (1972) 1.64
Decreased phagocytosis by peritoneal macrophages from BCG-treated mice: induction of the phagocytic defect in normal macrophages with BCG in vitro. Cell Immunol (1977) 1.61
Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway. Proc Natl Acad Sci U S A (2001) 1.60
The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control. J Immunol (1998) 1.60
Primary amyloidosis. Clinical, immunochemical and immunoglobulin metabolism. Studies in fifteen patients. Am J Med (1969) 1.60
IgG subclasses: development of the serum concentrations in "normal" infants and children. J Pediatr (1972) 1.59
The transformation of human lymphocytes by monkey antisera to human immunoglobulins. Immunology (1969) 1.59
Defect in IgA secretion and in IgA specific suppressor cells in patients with selective IgA deficiency. Trans Assoc Am Physicians (1976) 1.59
Normal human B cells display ordered light chain gene rearrangements and deletions. J Exp Med (1982) 1.58
Synergy between subpopulations of mouse spleen cells in the in vitro generation of cell-mediated cytotoxicity: evidence for the involvement of a non-T cell. J Exp Med (1974) 1.58
Contribution of a p75 interleukin 2 binding peptide to a high-affinity interleukin 2 receptor complex. Proc Natl Acad Sci U S A (1987) 1.57
Lymphocyte-macrophage interaction in antigen induced in vitro lymphocyte transformation in patients with the Wiskott-Aldrich syndrome and other diseases with anergy. Cell Immunol (1972) 1.56
Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-kappaB site. Proc Natl Acad Sci U S A (1998) 1.54
Loss of suppressor T cells in adult NZB/NZW mice. J Exp Med (1976) 1.52