Published in J Mol Biol on July 28, 1970
Replication and transcription of eukaryotic DNA in Escherichia coli. Proc Natl Acad Sci U S A (1974) 10.51
DNA methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes. Nucleic Acids Res (1979) 4.81
Variable patterns of total DNA and rDNA methylation in animals. Nucleic Acids Res (1980) 2.47
Amplified ribosomal DNA from Xenopus laevis has heterogeneous spacer lengths. Proc Natl Acad Sci U S A (1974) 2.42
Sequence organization of the spacer in the ribosomal genes of Xenopus clivii and Xenopus borealis. Nucleic Acids Res (1981) 2.27
Absence of cytosine methylation at C-C-G-G and G-C-G-C sites in the rDNA coding regions and intervening sequences of Drosophila and the rDNA of other insects. Nucleic Acids Res (1979) 2.10
The amplification of ribosomal RNA genes involves a rolling circle intermediate. Proc Natl Acad Sci U S A (1973) 2.07
Purification and some characteristics of 5S DNA from Xenopus laevis. Proc Natl Acad Sci U S A (1971) 2.03
DNA methylation and viral gene expression in adenovirus-transformed and -infected cells. Nucleic Acids Res (1980) 2.00
The sequence specificity of vertebrate DNA methylation. Nucleic Acids Res (1977) 1.57
Synthesis of amplified DNA that codes for ribosomal RNA. Proc Natl Acad Sci U S A (1971) 1.46
The occurrence of families of repetitive sequences in a library of cloned cDNA from human lymphocytes. Nucleic Acids Res (1981) 1.45
Deoxyribonucleic acid methylation and chromatin organization in Tetrahymena thermophila. Mol Cell Biol (1981) 1.43
Polyoma virus DNA: complete nucleotide sequence of the gene which codes for polyoma virus capsid protein VP1 and overlaps the VP2/VP3 genes. J Virol (1980) 1.36
Isolation and some properties of the genes coding for histone proteins. Proc Natl Acad Sci U S A (1974) 1.35
Methylation of chloroplast DNAs in the life cycle of Chlamydomonas. Proc Natl Acad Sci U S A (1979) 1.34
Hypomethylation of DNA during differentiation of Friend erythroleukemia cells. J Cell Biol (1980) 1.30
A novel DNA nucleotide in Trypanosoma brucei only present in the mammalian phase of the life-cycle. Nucleic Acids Res (1991) 1.29
Use of shuttle vectors to study the molecular processing of defined carcinogen-induced DNA damage: mutagenicity of single O4-ethylthymine adducts in HeLa cells. Nucleic Acids Res (1990) 1.13
Transcriptional organization of the 5.8S ribosomal RNA cistron in Xenopus laevis ribosomal DNA. Nucleic Acids Res (1977) 1.12
Multiple heterogeneities in the transcribed spacers of ribosomal DNA from Xenopus laevis. Nucleic Acids Res (1983) 1.08
18S coding sequences in amplified ribosomal DNA from Xenopus laevis oocytes are highly homogeneous, unmethylated, and lack major open reading frames. EMBO J (1982) 0.97
RNA-dependent DNA polymerase: possible role in the amplification of ribosomal DNA in Xenopus oocytes. Proc Natl Acad Sci U S A (1971) 0.93
Specific 5' and 3' regions of the mu-chain gene are undermethylated at distinct stages of B-cell differentiation. Proc Natl Acad Sci U S A (1985) 0.93
Morphology of nucleolar cistrons in a plant cell, Acetabularia mediterranea. Proc Natl Acad Sci U S A (1974) 0.91
[On the role of RNA in gene amplification]. Proc Natl Acad Sci U S A (1972) 0.90
Separation of DNA sequences complementary to the RNA of avian myeloblastosis virus from chicken DNA by alkaline cesium chloride density sedimentation. J Virol (1973) 0.86
Observations on early germ cell development and premeiotic ribosomal DNA amplification in Xenopus laevis. J Cell Biol (1974) 0.86
An RNA-DNA complex intermediate in ribosomal gene amplification. Proc Natl Acad Sci U S A (1972) 0.79
Amphibian ribosomal ribonucleic acids. Biochem J (1972) 0.78
Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin. Chromosome Res (2012) 0.76
Identification of a novel class of tandemly repeated genes transcribed on lampbrush chromosomes of Pleurodeles waltlii. J Cell Biol (1981) 0.75
The three-dimensional organization of the amplified ribosomal DNA complex in Acheta. Proc Natl Acad Sci U S A (1974) 0.75
E.B. Wilson Award Lecture, 1996. Differential gene action. Mol Biol Cell (1997) 0.75
Isolation of heavy satellite deoxyribonucleic acid from sea-urchin spermatozoa. Biochem J (1978) 0.75
Participation of deoxyribonucleic acid polymerase alpha in amplification of ribosomal deoxyribonucleic acid in Xenopus laevis. Mol Cell Biol (1981) 0.75
Contribution of transcription to animal early development. Transcription (2014) 0.75
Failure of IgG production due to a defect in the opening of the chromatin structure of I gamma 1 region in a patient with IgG and IgA deficiency. Clin Exp Immunol (1995) 0.75
Absence of ribosomal DNA amplification in the meroistic (telotrophic) ovary of the large milkweed bug Oncopeltus fasciatus (Dallas) (Hemiptera: Lygaeidae). J Cell Biol (1975) 0.75
A control region in the center of the 5S RNA gene directs specific initiation of transcription: I. The 5' border of the region. Cell (1980) 13.19
The nucleotide sequence of the initiation and termination sites for ribosomal RNA transcription in X. laevis. Cell (1979) 11.64
Analysis of C14-labeled proteins by disc electrophoresis. Biochem Biophys Res Commun (1965) 11.32
Repeated genes in eukaryotes. Annu Rev Biochem (1980) 11.23
A control region in the center of the 5S RNA gene directs specific initiation of transcription: II. The 3' border of the region. Cell (1980) 11.02
Mapping of mitochondrial DNA of individual sheep and goats: rapid evolution in the D loop region. Cell (1977) 8.64
Nucleotide sequences in Xenopus 5S DNA required for transcription termination. Cell (1981) 7.03
Specific gene amplification in oocytes. Oocyte nuclei contain extrachromosomal replicas of the genes for ribosomal RNA. Science (1968) 6.24
The nucleotide sequence of oocyte 5S DNA in Xenopus laevis. II. The GC-rich region. Cell (1978) 5.87
A specific transcription factor that can bind either the 5S RNA gene or 5S RNA. Proc Natl Acad Sci U S A (1980) 5.80
Stable transcription complexes of Xenopus 5S RNA genes: a means to maintain the differentiated state. Cell (1982) 5.46
A nuclear extract of Xenopus laevis oocytes that accurately transcribes 5S RNA genes. Cell (1978) 5.29
Evolution of mitochondrial DNA sequences in Xenopus. Dev Biol (1972) 5.28
Secondary structure maps of RNA: processing of HeLa ribosomal RNA. Proc Natl Acad Sci U S A (1973) 4.97
The structural organization of ribosomal DNA in Drosophila melanogaster. Cell (1977) 4.82
Nucleotide sequence of Xenopus borealis oocyte 5S DNA: comparison of sequences that flank several related eucaryotic genes. Cell (1978) 4.55
Vitellogenin in Xenopus laevis is encoded in a small family of genes. Cell (1979) 4.44
A gene expression screen. Proc Natl Acad Sci U S A (1991) 4.28
Domains of the positive transcription factor specific for the Xenopus 5S RNA gene. Cell (1984) 4.19
Contact points between a positive transcription factor and the Xenopus 5S RNA gene. Cell (1982) 4.15
Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature (1995) 4.14
Evidence for the mitochondrial origin of frog egg cytoplasmic DNA. Proc Natl Acad Sci U S A (1966) 3.99
Propagation of both parental mitochondrial DNAs in rat-human and mouse-human hybrid cells. J Mol Biol (1973) 3.93
Transient expression of genes introduced into cultured cells of Drosophila. Proc Natl Acad Sci U S A (1983) 3.93
Characterization of two xenopus somatic 5S DNAs and one minor oocyte-specific 5S DNA. Cell (1980) 3.78
The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. Nucleic Acids Res (1992) 3.57
Simulation technology for health care professional skills training and assessment. JAMA (1999) 3.49
Prehospital defibrillation performed by emergency medical technicians in rural communities. N Engl J Med (1984) 3.24
A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature (1999) 3.22
Nucleotide sequence of the initiation site for ribosomal RNA transcription in Drosophila melanogaster: comparison of genes with and without insertions. Proc Natl Acad Sci U S A (1981) 3.21
Expression of ribosomal DNA insertions in Drosophila melanogaster. Cell (1979) 3.19
The binding of a transcription factor to deletion mutants of a 5S ribosomal RNA gene. Cell (1981) 3.15
Differential gene expression in the gastrula of Xenopus laevis. Science (1983) 3.08
A comparison of the ribosomal DNA's of Xenopus laevis and Xenopus mulleri: the evolution of tandem genes. J Mol Biol (1972) 3.08
The role of stable complexes that repress and activate eucaryotic genes. Cell (1984) 3.08
Enhancer-like properties of the 60/81 bp elements in the ribosomal gene spacer of Xenopus laevis. Cell (1984) 2.93
Spacer regulation of Xenopus ribosomal gene transcription: competition in oocytes. Cell (1983) 2.85
The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains. Proc Natl Acad Sci U S A (1990) 2.85
Retention of common nucleotide sequences in the ribosomal deoxyribonucleic acid of eukaryotes and some of their physical characteristics. Biochemistry (1971) 2.82
Secondary structure maps of ribosomal RNA. II. Processing of mouse L-cell ribosomal RNA and variations in the processing pathway. J Mol Biol (1974) 2.82
Variants of the TATA-binding protein can distinguish subsets of RNA polymerase I, II, and III promoters. Cell (1992) 2.76
Maternal and cytoplasmic inheritance of mitochondrial DNA in Xenopus. Dev Biol (1972) 2.75
The molecular basis for length heterogeneity in ribosomal DNA from Xenopus laevis. J Mol Biol (1976) 2.75
Mesoderm induction in amphibians: the role of TGF-beta 2-like factors. Science (1988) 2.68
Characterization of three sites of RNA 3' end formation in the Xenopus ribosomal gene spacer. Cell (1986) 2.68
Ribosomal DNA in Drosophila melanogaster. I. Isolation and characterization of cloned fragments. J Mol Biol (1978) 2.68
The transcriptional regulation of Xenopus 5s RNA genes in chromatin: the roles of active stable transcription complexes and histone H1. Cell (1984) 2.67
Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins. Nature (1996) 2.57
A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter. Cell (1986) 2.52
Gene linkage by RNA-DNA hybridization. I. Unique DNA sequences homologous to 4 s RNA, 5 s RNA and ribosomal RNA. J Mol Biol (1968) 2.51
The nucleotide sequence of oocyte 5S DNA in Xenopus laevis. I. The AT-rich spacer. Cell (1978) 2.50
Decreased bioavailability of digoxin due to antacids and kaolin-pectin. N Engl J Med (1976) 2.48
Characterization and mapping of mitochondrial ribosomal RNA and mitochondrial DNA in Drosophila melanogaster. Cell (1976) 2.46
Amplified ribosomal DNA from Xenopus laevis has heterogeneous spacer lengths. Proc Natl Acad Sci U S A (1974) 2.42
A bacteriophage RNA polymerase transcribes through a Xenopus 5S RNA gene transcription complex without disrupting it. Cell (1986) 2.42
High-fidelity transcription of 5S DNA injected into Xenopus oocytes. Proc Natl Acad Sci U S A (1977) 2.42
Restriction analysis of the nontranscribed spacers of Xenopus laevis ribosomal DNA. Cell (1977) 2.40
Vitellogenesis and the vitellogenin gene family. Science (1981) 2.39
Enhancers and ribosomal gene spacers. Cell (1984) 2.39
The Drosophila fsh locus, a maternal effect homeotic gene, encodes apparent membrane proteins. Dev Biol (1989) 2.35
Adjacent repeating units of Xenopus laevis 5S DNA can be heterogeneous in length. Cell (1976) 2.31
The genes for silk fibroin in Bombyx mori. J Mol Biol (1972) 2.29
Molecular mechanisms governing species-specific transcription of ribosomal RNA. Cell (1989) 2.29
Purified RNA polymerase III accurately and efficiently terminates transcription of 5S RNA genes. Cell (1983) 2.28
Radiation hybrid mapping of the zebrafish genome. Proc Natl Acad Sci U S A (1999) 2.27
The structure and evolution of ribosomal and 5S DNAs in Xenopus laevis and Xenopus mulleri. Cold Spring Harb Symp Quant Biol (1974) 2.22
Mapping functional regions of transcription factor TFIIIA. Mol Cell Biol (1988) 2.22
Secondary structure maps of ribosomal RNA and DNA. I. Processing of Xenopus laevis ribosomal RNA and structure of single-stranded ribosomal DNA. J Mol Biol (1974) 2.21
Cocaine-induced myocardial infarction in patients with normal coronary arteries. Ann Intern Med (1991) 2.21
X and Y chromosomal ribosomal DNA of Drosophila: comparison of spacers and insertions. Cell (1978) 2.21
Formation and stability of the 5 S RNA transcription complex. J Biol Chem (1985) 2.20
Deoxyribonucleic acid in amphibian eggs. J Mol Biol (1965) 2.19
Epidermal keratin gene expressed in embryos of Xenopus laevis. Proc Natl Acad Sci U S A (1985) 2.16
A quantitative assay for Xenopus 5S RNA gene transcription in vitro. Cell (1981) 2.15
A family of oligo-adenylate-terminated transposable sequences in Drosophila melanogaster. J Mol Biol (1983) 2.14
The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF. Genes Dev (1989) 2.11
Ribosomal insertion-like elements in Drosophila melanogaster are interspersed with mobile sequences. Cell (1981) 2.08
A gene expression screen in zebrafish embryogenesis. Genome Res (2001) 2.08
Spacer sequences regulate transcription of ribosomal gene plasmids injected into Xenopus embryos. Cell (1983) 2.05
Developmental regulation of two 5S ribosomal RNA genes. Science (1988) 2.05
Restriction analysis of spacers in ribosomal DNA of Drosophila melanogaster. Nucleic Acids Res (1979) 2.04
The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. Genes Dev (1992) 2.04
A correlation of thyroid hormone receptor gene expression with amphibian metamorphosis. Genes Dev (1990) 2.03
Ribosomal RNA synthesis in isolated nuclei. J Mol Biol (1972) 2.03
Purification and some characteristics of 5S DNA from Xenopus laevis. Proc Natl Acad Sci U S A (1971) 2.03
A model for transcription termination by RNA polymerase I. Cell (1994) 2.00
Nested control regions promote Xenopus ribosomal RNA synthesis by RNA polymerase I. Cell (1983) 1.99
Mapping of transcription initiation and termination signals on Xenopus laevis ribosomal DNA. Proc Natl Acad Sci U S A (1982) 1.99
Sites of transcription initiation in vivo on Xenopus laevis ribosomal DNA. Proc Natl Acad Sci U S A (1977) 1.95
In-hospital cardiopulmonary resuscitation: a 30-year review. J Am Board Fam Pract (1993) 1.95
Ultracentrifuge and electron microscope studies on the structure of mitochondrial DNA. J Mol Biol (1967) 1.94
A bacteriophage RNA polymerase transcribes in vitro through a nucleosome core without displacing it. Cell (1987) 1.90
Efficacy of an automated external defibrillator in the management of out-of-hospital cardiac arrest: validation of the diagnostic algorithm and initial clinical experience in a rural environment. Circulation (1986) 1.90
Denaturation map of the ribosomal DNA of Xenopus laevis. J Mol Biol (1971) 1.89