Published in J Mol Biol on December 28, 1970
Predicting DNA duplex stability from the base sequence. Proc Natl Acad Sci U S A (1986) 21.73
Effects of methylation on a synthetic polynucleotide: the B--Z transition in poly(dG-m5dC).poly(dG-m5dC). Proc Natl Acad Sci U S A (1981) 8.07
Heteronomous DNA. Nucleic Acids Res (1983) 2.89
Complexes formed by (pyrimidine)n . (purine)n DNAs on lowering the pH are three-stranded. Nucleic Acids Res (1979) 2.62
DNA helical stability accounts for mutational defects in a yeast replication origin. Proc Natl Acad Sci U S A (1992) 1.93
Poly(dG).poly(dC) at neutral and alkaline pH: the formation of triple stranded poly(dG).poly(dG).poly(dC). Nucleic Acids Res (1978) 1.77
The binding of echinomycin to deoxyribonucleic acid. Biochem J (1976) 1.75
A Z-like form of poly(dA-dC).poly(dG-dT) in solution? Nucleic Acids Res (1982) 1.75
Interaction between synthetic analogues of quinoxaline antibiotics and nucleic acids. Changes in mechanism and specificity related to structural alterations. Biochem J (1978) 1.49
Escherichia coli polymerase I can use O2-methyldeoxythymidine or O4-methyldeoxythymidine in place of deoxythymidine in primed poly(dA-dT).poly(dA-dT) synthesis. Proc Natl Acad Sci U S A (1983) 1.41
Quantitative estimation of the contribution of pyrrolcarboxamide groups of the antibiotic distamycin A into specificity of its binding to DNA AT pairs. Nucleic Acids Res (1979) 1.38
Bifunctional intercalation and sequence specificity in the binding of quinomycin and triostin antibiotics to deoxyribonucleic acid. Biochem J (1978) 1.35
Interactions of 4', 6-diamidine-2-phenylindole with synthetic polynucleotides. Nucleic Acids Res (1979) 1.35
Mechanistic independence of avian myeloblastosis virus DNA polymerase and ribonuclease H. J Virol (1974) 1.33
The DNA binding site of the Xenopus transcription factor IIIA has a non-B-form structure. EMBO J (1989) 1.29
On the statistical significance of primary structural features found in DNA-protein interaction sites. Nucleic Acids Res (1975) 1.28
Lac repressor binding to synthetic DNAs of defined nucleotide sequence. Proc Natl Acad Sci U S A (1972) 1.26
Polypurine DNAs and RNAs form secondary structures which may be tetra-stranded. Nucleic Acids Res (1980) 1.24
Effect of 5-alkyl substitution of uracil on the thermal stability of poly [d(A-r5U)] copolymers. Nucleic Acids Res (1979) 1.22
Chiral probes for the handedness of DNA helices: enantiomers of tris(4,7-diphenylphenanthroline)ruthenium(II). Proc Natl Acad Sci U S A (1984) 1.22
Chain flexibility and hydrodynamics of the B and Z forms of poly(dG-dC).poly(dG-dC). Nucleic Acids Res (1983) 1.20
The interaction of ethidium with synthetic double-stranded polynucleotides at low ionic strength. Nucleic Acids Res (1978) 1.20
Evidence from CD spectra that d(purine).r(pyrimidine) and r(purine).d(pyrimidine) hybrids are in different structural classes. Nucleic Acids Res (1994) 1.20
DNA CTG triplet repeats involved in dynamic mutations of neurologically related gene sequences form stable duplexes. Nucleic Acids Res (1995) 1.20
Evidence for Z-form RNA by vacuum UV circular dichroism. Nucleic Acids Res (1985) 1.18
Mung bean nuclease cleavage of a dA + dT-rich sequence or an inverted repeat sequence in supercoiled PM2 DNA depends on ionic environment. Nucleic Acids Res (1984) 1.15
Protonated polynucleotides structures - 22.CD study of the acid-base titration of poly(dG).poly(dC). Nucleic Acids Res (1978) 1.13
A comparison of the circular dichroism spectra of synthetic DNA sequences of the homopurine . homopyrimidine and mixed purine- pyrimidine types. Nucleic Acids Res (1978) 1.13
Fluorescence-determined preferential binding of quinacrine to DNA. Biophys J (1981) 1.11
BAL 31 nuclease as a probe in concentrated salt for the B-Z DNA junction. Nucleic Acids Res (1983) 1.11
A monoclonal antibody to triplex DNA binds to eucaryotic chromosomes. Nucleic Acids Res (1987) 1.08
Toward a detailed description of the thermally induced dynamics of the core promoter. PLoS Comput Biol (2009) 1.07
5-Hydroxymethyluracil in the DNA of a dinoflagellate. Proc Natl Acad Sci U S A (1973) 1.04
The sequence dependence of circular dichroism spectra of DNA duplexes. Nucleic Acids Res (1975) 1.04
Characterization of a novel DNA minor-groove complex. Biophys J (2004) 1.04
Nucleoside diphosphokinase activity associated with DNA polymerases. Proc Natl Acad Sci U S A (1971) 1.04
DNA-like duplexes with repetitions. I. Properties of concatemer duplexes formed by d(T-G-C-A-C-A-T-G). Nucleic Acids Res (1980) 1.03
DNA dynamics play a role as a basal transcription factor in the positioning and regulation of gene transcription initiation. Nucleic Acids Res (2009) 1.03
A simple method for the computation of first neighbour frequencies of DNAs from CD spectra. Nucleic Acids Res (1978) 1.03
Junction between Z and B conformations in a DNA restriction fragment: evaluation by Raman spectroscopy. Proc Natl Acad Sci U S A (1982) 1.02
Mechanistic studies of polyene enhancement of interferon production by polyriboinosinic-polyribocytidylic acid. Antimicrob Agents Chemother (1978) 1.01
Entropically-driven binding of mithramycin in the minor groove of C/G-rich DNA sequences. Nucleic Acids Res (2007) 1.01
A nonlinear dynamic model of DNA with a sequence-dependent stacking term. Nucleic Acids Res (2009) 1.00
Breakage of parental DNA strands in Haemophilus influenzae by 313 nm radiation after replication in the presence of 5-bromodeoxyuridine. Biophys J (1972) 0.99
CD of six different conformational rearrangements of poly[d(A-G).d(C-T)] induced by low pH. Nucleic Acids Res (1988) 0.99
Dehydrating agents sharply reduce curvature in DNAs containing A tracts. Nucleic Acids Res (1995) 0.98
Salt dependence and thermodynamic interpretation of the thermal denaturation of small DNA restriction fragments. Nucleic Acids Res (1981) 0.97
Thermodynamics of nucleic acid "shape readout" by an aminosugar. Biochemistry (2011) 0.96
Protonated polynucleotides structures - 23. The acid-base hysteresis of poly(dG).poly(dC). Nucleic Acids Res (1978) 0.96
Circular dichroism studies of the B goes to A conformational transition in seven small DNA restriction fragments containing the Escherichia coli lactose control region. Nucleic Acids Res (1980) 0.96
Conformational transitions of alternating purine-pyrimidine DNAs in perchlorate ethanol solutions. Biophys J (1995) 0.95
Modified polynucleotides. VI. Properties of a synthetic DNA containing the anti-herpes agent (E)-5-(2-bromovinyl)-2'-deoxyuridine. Nucleic Acids Res (1982) 0.94
The influence of ionic strength on the binding of a water soluble porphyrin to nucleic acids. Nucleic Acids Res (1986) 0.92
The circular dichroism and X-ray diffraction of DNA condensed from ethanolic solutions. Nucleic Acids Res (1979) 0.91
Reaction of cis-diamminedichloroplatinum (II) and DNA in B or Z conformation. EMBO J (1984) 0.91
Circular dichroism spectra of twelve short DNA restriction fragments of known sequence: a comparison of measured and calculated spectra. Nucleic Acids Res (1981) 0.91
Mode of reversible binding of neocarzinostatin chromophore to DNA: base sequence dependency of binding. Nucleic Acids Res (1986) 0.90
Thermodynamics of the interactions of m-AMSA and o-AMSA with nucleic acids: influence of ionic strength and DNA base composition. Nucleic Acids Res (1989) 0.89
Micro-volume couette flow sample orientation for absorbance and fluorescence linear dichroism. Biophys J (2004) 0.87
Phosphoramidites of base-modified 2'-deoxyinosine isosteres and solid-phase synthesis of d(GCI*CGC) oligomers containing an ambiguous base. Nucleic Acids Res (1986) 0.86
Variations in duplex DNA conformation detected by the binding of monoclonal autoimmune antibodies. Nucleic Acids Res (1986) 0.86
Unusual DNA structure in the regulatory region of the human papovavirus JC virus. J Virol (1988) 0.86
Monoclonal antibodies to DNA modified with cis- or trans-diamminedichloroplatinum(II). Proc Natl Acad Sci U S A (1987) 0.85
In vitro synthesis of uniform poly(dG)-poly(dC) by Klenow exo- fragment of polymerase I. Nucleic Acids Res (2005) 0.85
Characterization of imperfect DNA duplexes containing unpaired bases and non-Watson-Crick base pairs. Nucleic Acids Res (1986) 0.84
Immunological and spectroscopic studies of poly(dG-dC).poly(dG-dC) modified by cis-diamminedichloroplatinum(II). Nucleic Acids Res (1984) 0.84
Electron microscopy of the reactions of anti-poly A. poly U and anti-poly I. poly C antibodies with synthetic polynucleotide complexes and natural nucleic acids. Nucleic Acids Res (1980) 0.84
Diepoxybutane forms a monoadduct with B-form (dG-dC)n.(dG-dC)n and a crosslinked diadduct with the left-handed Z-form. Nucleic Acids Res (1985) 0.83
Helix stability and the mechanism of cruciform extrusion in supercoiled DNA molecules. Nucleic Acids Res (1988) 0.82
Preparation of triple-block DNA polymers using recombinant DNA techniques. Nucleic Acids Res (1979) 0.82
Stabilization of triple-stranded oligonucleotide complexes: use of probes containing alternating phosphodiester and stereo-uniform cationic phosphoramidate linkages. Nucleic Acids Res (1996) 0.82
Isolation and physicochemical characterisation of the DNA from normal human skin and psoriatic scales. Arch Dermatol Res (1976) 0.79
Opening the Strands of Replication Origins-Still an Open Question. Front Mol Biosci (2016) 0.78
Thermodynamic analysis of monoclonal antibody binding to duplex DNA. Nucleic Acids Res (1997) 0.77
Conformation and reactivity of DNA in the complex with protein. IV. Circular dichroism of poly-L-histidine model complexes with DNA polymers and specificity of the interaction. Nucleic Acids Res (1976) 0.76
The genes for ribosomal ribonucleic acid. Biochem J (1972) 0.75
Time-resolved fluorescence studies of tomaymycin bonding to synthetic DNAs. Biophys J (1996) 0.75
First- or second-order transition in the melting of repeat sequence DNA. Biophys J (1994) 0.75
CD evidence that the alternating purine-pyrimidine sequence poly[d(A-C).d(G-T)], but not poly[d(A-T).d(A-T)], undergoes an acid-induced transition to a modified secondary conformation. Nucleic Acids Res (1990) 0.75
Quenching enhancement of the singlet excited state of pheophorbide-a by DNA in the presence of the quinone carboquone. Photochem Photobiol (2011) 0.75
Temperature and osmotic stress dependence of the thermodynamics for binding linker histone H1(0), Its carboxyl domain (H1(0)-C) or globular domain (H1(0)-G) to B-DNA. Biochem Biophys Rep (2017) 0.75
Synthesis and photophysical properties of zinc myoglobin appending an ethidium ion as a DNA intercalator. J Biol Inorg Chem (2007) 0.75
Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell (1984) 31.52
Construction of a genetic toggle switch in Escherichia coli. Nature (2000) 24.02
Microtubule assembly in the absence of added nucleotides. Proc Natl Acad Sci U S A (1973) 18.46
A physical map of the Escherichia coli K12 genome. Science (1987) 8.42
Purification, specific fragmentation, and separation of large DNA molecules. Methods Enzymol (1987) 7.40
New techniques for purifying large DNAs and studying their properties and packaging. Cold Spring Harb Symp Quant Biol (1983) 6.35
Cruciform structures in supercoiled DNA. Nature (1981) 6.29
Oligonucleotide interactions. 3. Circular dichroism studies of the conformation of deoxyoligonucleotides. Biopolymers (1970) 6.03
A rapid microscale technique for isolation of recombinant plasmid DNA suitable for restriction enzyme analysis. Plasmid (1980) 5.77
Chip-based genotyping by mass spectrometry. Proc Natl Acad Sci U S A (1999) 5.63
Conserved 5S rRNA complement to tRNA is not required for protein synthesis. Proc Natl Acad Sci U S A (1982) 5.54
Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules. J Mol Biol (1974) 5.00
Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions. Nature (1982) 4.50
High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Proc Natl Acad Sci U S A (2001) 4.31
Antigenic variation in Trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules. Cell (1984) 4.03
Construction of a Not I restriction map of the fission yeast Schizosaccharomyces pombe genome. Nucleic Acids Res (1989) 3.95
Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus. EMBO J (1988) 3.82
The synthesis and purification of (gamma-32P)-adenosine triphosphate with high specific activity. J Biol Chem (1973) 3.74
An electrophoretic karyotype for Schizosaccharomyces pombe by pulsed field gel electrophoresis. Nucleic Acids Res (1987) 3.59
Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences. J Mol Biol (1968) 3.53
Immuno-PCR: very sensitive antigen detection by means of specific antibody-DNA conjugates. Science (1992) 3.49
Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. J Biol Chem (1999) 3.40
Recognition and initiation site for four late promoters of phage T7 is a 22-base pair DNA sequence. Nature (1979) 3.28
'Single-stranded' DNA from phiX174 and M13 is cleaved by certain restriction endonucleases. Nature (1975) 3.27
Reversal of cystic fibrosis phenotype in mice by gene therapy in utero. Lancet (1997) 3.15
Netropsin. A specific probe for A-T regions of duplex deoxyribonucleic acid. J Biol Chem (1974) 3.12
In silico detection of control signals: mRNA 3'-end-processing sequences in diverse species. Proc Natl Acad Sci U S A (1999) 3.08
Left-handed DNA in restriction fragments and a recombinant plasmid. Nature (1981) 3.06
Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli. Nat Genet (1995) 2.99
DNA structure and gene regulation. Prog Nucleic Acid Res Mol Biol (1980) 2.88
Endosome pH measured in single cells by dual fluorescence flow cytometry: rapid acidification of insulin to pH 6. J Cell Biol (1984) 2.76
Strategies for mapping and cloning macroregions of mammalian genomes. Methods Enzymol (1987) 2.68
Genomic detection of new yeast pre-mRNA 3'-end-processing signals. Nucleic Acids Res (1999) 2.58
Studies of transfer RNA tertiary structure by singlet-singlet energy transfer. Proc Natl Acad Sci U S A (1970) 2.56
A circular dichroism study of microtubule protein. Biochemistry (1972) 2.51
Stabilization of Z DNA in vivo by localized supercoiling. Science (1989) 2.45
Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase. J Biol Chem (1987) 2.44
A dynein-like protein associated with neurotubules. FEBS Lett (1974) 2.38
Intramolecular DNA triplexes in supercoiled plasmids. Proc Natl Acad Sci U S A (1988) 2.37
Molecular cloning and nucleotide sequence of the streptavidin gene. Nucleic Acids Res (1986) 2.30
A strategy for rapid and efficient DNA sequencing by mass spectrometry. Nat Biotechnol (1996) 2.30
Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia. Mol Cell (1999) 2.21
Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo. J Biol Chem (1998) 2.19
Bent DNA: visualization of a base-paired and stacked A-B conformational junction. J Biol Chem (1979) 2.18
The use of singlet-singlet energy transfer to study macromolecular assemblies. Methods Enzymol (1978) 2.13
Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix. Nucleic Acids Res (1990) 2.12
Characterization and crystallization of core streptavidin. J Biol Chem (1987) 2.09
Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences. J Mol Biol (1967) 2.06
Physical and enzymatic studies on poly d(I-C)-poly d(I-C), an unusual double-helical DNA. Nature (1970) 2.04
Megabase-scale mapping of the HLA gene complex by pulsed field gel electrophoresis. Science (1987) 2.01
Preferential nucleosome assembly at DNA triplet repeats from the myotonic dystrophy gene. Science (1994) 1.99
A stable complex between homopyrimidine oligomers and the homologous regions of duplex DNAs. Nucleic Acids Res (1988) 1.96
Action of single-strand specific nucleases on model DNA heteroduplexes of defined size and sequence. Biochemistry (1977) 1.94
Synthesis and thermal melting behavior of oligomer-polymer complexes containing defined lengths of mismatched dA-dG and dG-dG nucleotides. Biochemistry (1977) 1.92
Left-handed DNA in vivo. Science (1987) 1.92
Sequencing exons 5 to 8 of the p53 gene by MALDI-TOF mass spectrometry. Nat Biotechnol (1998) 1.87
Heat shock genes: regulatory role for differentiation in parasitic protozoa. Science (1985) 1.85
S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences. J Biol Chem (1984) 1.85
Duplex regions in "single-stranded" phiX174 DNA are cleaved by a restriction endonuclease from Haemophilus aegyptius. J Biol Chem (1977) 1.85
Carcinoma of the cervix treated with radiation therapy. I. A multi-variate analysis of prognostic variables in the Gynecologic Oncology Group. Cancer (1991) 1.85
Transmission of stability (telestability) in deoxyribonucleic acid. Physical and enzymatic studies on the duplex block polymer d(C15A15) - d(T15G15). J Biol Chem (1975) 1.83
DNA structure, mutations, and human genetic disease. Curr Opin Biotechnol (1992) 1.83
Reversible changes in nucleosome structure and histone H3 accessibility in transcriptionally active and inactive states of rDNA chromatin. Cell (1983) 1.82
Studies on the binding of actinomycin D to DNA and DNA model polymers. J Mol Biol (1970) 1.81
The role of DNA structure in genetic regulation. CRC Crit Rev Biochem (1977) 1.81
Preparation and characterization of large amounts of restriction fragments containing the E. coli lac control elements. Gene (1979) 1.81
Influence of DNA sequence on the formation of non-B right-handed helices in oligopurine.oligopyrimidine inserts in plasmids. J Biol Chem (1988) 1.77
Preparative fractionation of DNA restriction fragments by reversed phase column chromatography. Proc Natl Acad Sci U S A (1976) 1.77
Preparation of milligram amounts of 21 deoxyribonucleic acid restriction fragments. Biochemistry (1981) 1.73
Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes. J Biol Chem (1995) 1.71
Physical characterization of a kinetoplast DNA fragment with unusual properties. J Biol Chem (1984) 1.71
Conditions which cause the right-handed to left-handed DNA conformational transitions. Evidence for several types of left-handed DNA structures in solution. J Biol Chem (1982) 1.70
Nucleosomes are phased along the mouse beta-major globin gene in erythroid and nonerythroid cells. Cell (1986) 1.70
Micrococcus luteus deoxyribonucleic acid polymerase. Studies on the initiation of deoxyribonucleic acid synthesis in vitro. J Biol Chem (1970) 1.70
PCR amplification of megabase DNA with tagged random primers (T-PCR). Nucleic Acids Res (1993) 1.69
Sequence-specific DNA purification by triplex affinity capture. Proc Natl Acad Sci U S A (1992) 1.69
Coumerimycin A1: A preferential inhibitor of replicative DNA synthesis in Escherichia coli. II. In vivo characterization. Biochemistry (1976) 1.67
Possible structures of homopurine-homopyrimidine S1-hypersensitive sites. Nucleic Acids Res (1984) 1.67
Oligonucleotide interactions. IV. Conformational differences between deoxy- and ribodinucleoside phosphates. Biopolymers (1970) 1.67
A highly bent fragment of Crithidia fasciculata kinetoplast DNA. J Biol Chem (1986) 1.66
Expression of a cloned streptavidin gene in Escherichia coli. Proc Natl Acad Sci U S A (1990) 1.66
Energetic and structural inter-relationship between DNA supercoiling and the right- to left-handed Z helix transitions in recombinant plasmids. J Biol Chem (1982) 1.65
The facile generation of covalently closed, circular DNAs with defined negative superhelical densities. Anal Biochem (1982) 1.62
Enhanced DNA sequencing by hybridization. Proc Natl Acad Sci U S A (1994) 1.61
Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B. Proc Natl Acad Sci U S A (1986) 1.59
Intervening sequences in human fetal globin genes adopt left-handed Z helices. J Biol Chem (1984) 1.58
Nucleotides at the RNA-DNA covalent bonds formed in the endogenous reaction by the avian myeloblastosis virus DNA polymerase. Virology (1972) 1.58
Comparison of some reactions catalyzed by deoxyribonucleic acid polymerase from avian myeloblastosis virus, Escherichia coli, and Micrococcus luteus. Biochemistry (1972) 1.58
Construction and mapping of recombinant plasmids used for the preparation of DNA fragments containing the Escherichia coli lactose operator and promoter. J Biol Chem (1979) 1.57