Published in J Biol Chem on February 10, 1984
Enhanced gene expression by the poly(dT-dG).poly(dC-dA) sequence. Mol Cell Biol (1984) 4.44
Characterization of genomic poly(dT-dG).poly(dC-dA) sequences: structure, organization, and conformation. Mol Cell Biol (1984) 3.42
The ubiquitous potential Z-forming sequence of eucaryotes, (dT-dG)n . (dC-dA)n, is not detectable in the genomes of eubacteria, archaebacteria, or mitochondria. Mol Cell Biol (1986) 3.00
The evolutionarily conserved repetitive sequence d(TG.AC)n promotes reciprocal exchange and generates unusual recombinant tetrads during yeast meiosis. Mol Cell Biol (1986) 2.86
d(TG)n.d(CA)n sequences upstream of the rat prolactin gene form Z-DNA and inhibit gene transcription. Nucleic Acids Res (1990) 1.99
The Z-DNA motif d(TG)30 promotes reception of information during gene conversion events while stimulating homologous recombination in human cells in culture. Mol Cell Biol (1990) 1.91
S1-hypersensitive sites in eukaryotic promoter regions. Nucleic Acids Res (1984) 1.88
Structure of an inverted duplication formed as a first step in a gene amplification event: implications for a model of gene amplification. EMBO J (1987) 1.68
Recombination hot spot in the human beta-globin gene cluster: meiotic recombination of human DNA fragments in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.63
(A-T)n tracts embedded in random sequence DNA--formation of a structure which is chemically reactive and torsionally deformable. Nucleic Acids Res (1986) 1.50
Kinking the double helix by bending deformation. Nucleic Acids Res (2007) 1.48
Altered DNA conformations detected by mung bean nuclease occur in promoter and terminator regions of supercoiled pBR322 DNA. Nucleic Acids Res (1985) 1.46
Yeast regulatory sequences preferentially adopt a non-B conformation in supercoiled DNA. Nucleic Acids Res (1987) 1.38
Consecutive A X T pairs can adopt a left-handed DNA structure. Proc Natl Acad Sci U S A (1986) 1.33
The B- to Z-DNA equilibrium in vivo is perturbed by biological processes. Proc Natl Acad Sci U S A (1988) 1.27
Mung bean nuclease cleavage of a dA + dT-rich sequence or an inverted repeat sequence in supercoiled PM2 DNA depends on ionic environment. Nucleic Acids Res (1984) 1.15
HhaI methylase and restriction endonuclease as probes for B to Z DNA conformational changes in d(GCGC) sequences. Nucleic Acids Res (1984) 1.13
Atomistic simulations reveal bubbles, kinks and wrinkles in supercoiled DNA. Nucleic Acids Res (2011) 1.12
The structure of cruciforms in supercoiled DNA: probing the single-stranded character of nucleotide bases with bisulphite. EMBO J (1986) 1.09
Homologous recombination enhancement conferred by the Z-DNA motif d(TG)30 is abrogated by simian virus 40 T antigen binding to adjacent DNA sequences. Mol Cell Biol (1990) 1.02
DNase I-resistant nontranscribed spacer segments of mouse ribosomal DNA contain poly(dG-dT).poly(dA-dC). Proc Natl Acad Sci U S A (1985) 0.96
Reaction conditions affect the specificity of bromoacetaldehyde as a probe for DNA cruciforms and B-Z junctions. Nucleic Acids Res (1987) 0.95
Nuclease recognition of an alternating structure in a d(AT)14 plasmid insert. Nucleic Acids Res (1986) 0.93
Nuclease sensitivity of the mouse HPRT gene promoter region: differential sensitivity on the active and inactive X chromosomes. Mol Cell Biol (1987) 0.88
Unusual DNA structure in the regulatory region of the human papovavirus JC virus. J Virol (1988) 0.86
The histone H5 gene is flanked by S1 hypersensitive structures. Nucleic Acids Res (1984) 0.85
Immunological and spectroscopic studies of poly(dG-dC).poly(dG-dC) modified by cis-diamminedichloroplatinum(II). Nucleic Acids Res (1984) 0.84
Diepoxybutane forms a monoadduct with B-form (dG-dC)n.(dG-dC)n and a crosslinked diadduct with the left-handed Z-form. Nucleic Acids Res (1985) 0.83
Relevance of sequence and structure elements for deletion events in the dystrophin gene major hot-spot. Hum Genet (2002) 0.83
Altered DNA conformations in the gene regulatory region of torsionally-stressed SV40 DNA. Nucleic Acids Res (1986) 0.80
DNA duplex with the potential to change handedness after every half a turn. Nucleic Acids Res (1989) 0.79
Structural interconversion of alternating purine-pyrimidine inverted repeats cloned in supercoiled plasmids. Nucleic Acids Res (1988) 0.78
PPG peptide nucleic acids that promote DNA guanine quadruplexes. Chembiochem (2014) 0.77
Comparison of the reactivity of B-DNA and Z-DNA with two isosteric chemical carcinogens: 2-N,N-acetoxyacetylaminofluorene and 3-N,N-acetoxyacetylamino-4,6-dimethyldipyrido-[1,2-a:3',2' -d] imidazole. Nucleic Acids Res (1987) 0.75
Cruciform structures in supercoiled DNA. Nature (1981) 6.29
A rapid microscale technique for isolation of recombinant plasmid DNA suitable for restriction enzyme analysis. Plasmid (1980) 5.77
Physicochemical studies on polydeoxyribonucleotides containing defined repeating nucleotide sequences. J Mol Biol (1970) 5.21
Left-handed Z-DNA is induced by supercoiling in physiological ionic conditions. Nature (1982) 4.50
The synthesis and purification of (gamma-32P)-adenosine triphosphate with high specific activity. J Biol Chem (1973) 3.74
Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences. J Mol Biol (1968) 3.53
Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. J Biol Chem (1999) 3.40
Protected deoxyribonucleoside-3' aryl phosphodiesters as key intermediates in polynucleotide synthesis. Construction of an icosanucleotide analogous to the sequence at the ends of Rous sarcoma virus 35S RNA. Nucleic Acids Res (1979) 3.40
Recognition and initiation site for four late promoters of phage T7 is a 22-base pair DNA sequence. Nature (1979) 3.28
'Single-stranded' DNA from phiX174 and M13 is cleaved by certain restriction endonucleases. Nature (1975) 3.27
Netropsin. A specific probe for A-T regions of duplex deoxyribonucleic acid. J Biol Chem (1974) 3.12
Left-handed DNA in restriction fragments and a recombinant plasmid. Nature (1981) 3.06
Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli. Nat Genet (1995) 2.99
DNA structure and gene regulation. Prog Nucleic Acid Res Mol Biol (1980) 2.88
The intracellular signal for induction of resistance to alkylating agents in E. coli. Cell (1986) 2.77
DNA sequence of the E. coli trpR gene and prediction of the amino acid sequence of Trp repressor. Nucleic Acids Res (1980) 2.72
Stabilization of Z DNA in vivo by localized supercoiling. Science (1989) 2.45
Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase. J Biol Chem (1987) 2.44
Location of gene for Gorlin syndrome. Lancet (1992) 2.41
Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1. Nat Genet (1997) 2.38
Intramolecular DNA triplexes in supercoiled plasmids. Proc Natl Acad Sci U S A (1988) 2.37
Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia. Mol Cell (1999) 2.21
Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo. J Biol Chem (1998) 2.19
Bent DNA: visualization of a base-paired and stacked A-B conformational junction. J Biol Chem (1979) 2.18
Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix. Nucleic Acids Res (1990) 2.12
Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences. J Mol Biol (1967) 2.06
Physical and enzymatic studies on poly d(I-C)-poly d(I-C), an unusual double-helical DNA. Nature (1970) 2.04
The nucleotide sequence of the 5S rRNA from the archaebacterium Thermoplasma acidophilum. Nucleic Acids Res (1981) 2.01
Preferential nucleosome assembly at DNA triplet repeats from the myotonic dystrophy gene. Science (1994) 1.99
Split-hand/split-foot malformation is caused by mutations in the p63 gene on 3q27. Am J Hum Genet (2000) 1.98
Action of single-strand specific nucleases on model DNA heteroduplexes of defined size and sequence. Biochemistry (1977) 1.94
Left-handed DNA in vivo. Science (1987) 1.92
Synthesis and thermal melting behavior of oligomer-polymer complexes containing defined lengths of mismatched dA-dG and dG-dG nucleotides. Biochemistry (1977) 1.92
Duplex regions in "single-stranded" phiX174 DNA are cleaved by a restriction endonuclease from Haemophilus aegyptius. J Biol Chem (1977) 1.85
Transmission of stability (telestability) in deoxyribonucleic acid. Physical and enzymatic studies on the duplex block polymer d(C15A15) - d(T15G15). J Biol Chem (1975) 1.83
DNA structure, mutations, and human genetic disease. Curr Opin Biotechnol (1992) 1.83
Studies on the binding of actinomycin D to DNA and DNA model polymers. J Mol Biol (1970) 1.81
The role of DNA structure in genetic regulation. CRC Crit Rev Biochem (1977) 1.81
Preparation and characterization of large amounts of restriction fragments containing the E. coli lac control elements. Gene (1979) 1.81
The nucleotide sequence of glycine tRNA from Mycoplasma mycoides sp. capri. Nucleic Acids Res (1980) 1.77
Influence of DNA sequence on the formation of non-B right-handed helices in oligopurine.oligopyrimidine inserts in plasmids. J Biol Chem (1988) 1.77
Preparative fractionation of DNA restriction fragments by reversed phase column chromatography. Proc Natl Acad Sci U S A (1976) 1.77
Preparation of milligram amounts of 21 deoxyribonucleic acid restriction fragments. Biochemistry (1981) 1.73
Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes. J Biol Chem (1995) 1.71
Physical characterization of a kinetoplast DNA fragment with unusual properties. J Biol Chem (1984) 1.71
Conditions which cause the right-handed to left-handed DNA conformational transitions. Evidence for several types of left-handed DNA structures in solution. J Biol Chem (1982) 1.70
Micrococcus luteus deoxyribonucleic acid polymerase. Studies on the initiation of deoxyribonucleic acid synthesis in vitro. J Biol Chem (1970) 1.70
Coumerimycin A1: A preferential inhibitor of replicative DNA synthesis in Escherichia coli. II. In vivo characterization. Biochemistry (1976) 1.67
A highly bent fragment of Crithidia fasciculata kinetoplast DNA. J Biol Chem (1986) 1.66
Energetic and structural inter-relationship between DNA supercoiling and the right- to left-handed Z helix transitions in recombinant plasmids. J Biol Chem (1982) 1.65
Supercoiling and integration host factor change the DNA conformation and alter the flow of convergent transcription in phage Mu. J Biol Chem (1989) 1.64
Duplication of the 15q11-13 region in a patient with autism, epilepsy and ataxia. Dev Med Child Neurol (1994) 1.63
The facile generation of covalently closed, circular DNAs with defined negative superhelical densities. Anal Biochem (1982) 1.62
Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B. Proc Natl Acad Sci U S A (1986) 1.59
Intervening sequences in human fetal globin genes adopt left-handed Z helices. J Biol Chem (1984) 1.58
Nucleotides at the RNA-DNA covalent bonds formed in the endogenous reaction by the avian myeloblastosis virus DNA polymerase. Virology (1972) 1.58
Comparison of some reactions catalyzed by deoxyribonucleic acid polymerase from avian myeloblastosis virus, Escherichia coli, and Micrococcus luteus. Biochemistry (1972) 1.58
Construction and mapping of recombinant plasmids used for the preparation of DNA fragments containing the Escherichia coli lactose operator and promoter. J Biol Chem (1979) 1.57
Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription. J Biol Chem (2001) 1.56
Spectroscopic studies on acetylaminofluorene-modified (dT-dG)n . (dC-dA)n suggest a left-handed conformation. J Biol Chem (1982) 1.56
RNA polymerase binding sites in lambdaplac5 DNA. Proc Natl Acad Sci U S A (1977) 1.54
The segment inversion site of herpes simplex virus type 1 adopts a novel DNA structure. J Biol Chem (1987) 1.54
Influence of sequence and distance between two operators on interaction with the lac repressor. J Biol Chem (1987) 1.51
Non-B right-handed DNA conformations of homopurine.homopyrimidine sequences in the murine immunoglobulin C alpha switch region. J Biol Chem (1988) 1.49
The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders. Prog Nucleic Acid Res Mol Biol (2001) 1.44
Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases. Proc Natl Acad Sci U S A (1995) 1.40
Orientation relaxation of DNA restriction fragments and the internal mobility of the double helix. Biophys Chem (1982) 1.40
Direct evidence for the effect of transcription on local DNA supercoiling in vivo. J Mol Biol (1992) 1.40
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Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B. J Mol Biol (1967) 1.38
Unusual DNA structures in the adenovirus genome. J Biol Chem (1986) 1.38
Acheiropodia is caused by a genomic deletion in C7orf2, the human orthologue of the Lmbr1 gene. Am J Hum Genet (2000) 1.38
Genetic instabilities in (CTG.CAG) repeats occur by recombination. J Biol Chem (1999) 1.37
Relationship between superhelical density and cruciform formation in plasmid pVH51. J Biol Chem (1982) 1.37
Marfan syndrome: no evidence for heterogeneity in different populations, and more precise mapping of the gene. Am J Hum Genet (1991) 1.35
Influence of supercoiling and sequence context on operator DNA binding with lac repressor. J Biol Chem (1987) 1.35
Mechanistic independence of avian myeloblastosis virus DNA polymerase and ribonuclease H. J Virol (1974) 1.33
Long CCG triplet repeat blocks exclude nucleosomes: a possible mechanism for the nature of fragile sites in chromosomes. J Mol Biol (1996) 1.33
Transcription increases the deletion frequency of long CTG.CAG triplet repeats from plasmids in Escherichia coli. Nucleic Acids Res (1997) 1.33
Consecutive A X T pairs can adopt a left-handed DNA structure. Proc Natl Acad Sci U S A (1986) 1.33
Left-handed DNA. Cloning, characterization, and instability of inserts containing different lengths of (dC-dG) in Escherichia coli. J Biol Chem (1982) 1.32
A 300- and 600-MHz proton nuclear magnetic resonance investigation of a 12 base pair deoxyribonucleic acid restriction fragment: relaxation behavior of the low-field resonances in water. Biochemistry (1981) 1.32
RPC-5 column chromatography for the isolation of DNA fragments. Methods Enzymol (1980) 1.32
Polynucleotide synthesis and the genetic code. Cold Spring Harb Symp Quant Biol (1966) 1.31
Effect of incubation conditions on the nucleotide sequence of DNA products of unprimed DNA polymerase reactions. J Mol Biol (1970) 1.31
RNA-DNA covalent bonds between the RNA primers and the DNA products formed by RNA tumor virus DNA polymerase. J Virol (1973) 1.30
Conformational flexibility of junctions between contiguous B- and Z-DNAs in supercoiled plasmids. Proc Natl Acad Sci U S A (1983) 1.28
Studies on polynucleotides. L. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: a new double-stranded DNA-like polymer containing repeating dinucleotide sequences. J Mol Biol (1965) 1.28
Supercoiling facilitates lac operator-repressor-pseudooperator interactions. J Biol Chem (1987) 1.28
Recombinant human DNA (cytosine-5) methyltransferase. II. Steady-state kinetics reveal allosteric activation by methylated dna. J Biol Chem (1999) 1.27
The B- to Z-DNA equilibrium in vivo is perturbed by biological processes. Proc Natl Acad Sci U S A (1988) 1.27