Published in Biochem Biophys Res Commun on January 08, 1971
Protein kinase activity in equine herpesvirus. J Virol (1972) 2.21
Thrombin-induced protein phosphorylation in human platelets. J Clin Invest (1975) 1.76
Simian virus 40 gene A regulates the association between a highly phosphorylated protein and chromatin and ribosomes in simian virus 40-transformed cells. J Virol (1977) 1.15
Effects of polyamines on prostatic chromatin- and non-histone-protein-associated protein kinase reactions. Biochem J (1978) 0.97
Further characterization of the F1-histone phosphokinase of metaphase-arrested animal cells. J Cell Biol (1973) 0.97
Multiple protein kinases from human lymphocytes. Identification enzymes phosphorylating exogenous histon and casein. Biochem J (1975) 0.86
Purification and properties of a ribosomal casein kinase from rabbit reticulocytes. Biochem J (1977) 0.79
Purification and properties of a nuclear protein kinase from rat mammary gland. Biochem J (1977) 0.75
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science (1998) 21.13
Nuclear genes encoding the yeast mitochondrial ATPase complex. Analysis of ATP1 coding the F1-ATPase alpha-subunit and its assembly. J Biol Chem (1986) 4.51
Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways. EMBO J (1994) 4.23
Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A (1981) 4.12
The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal. J Cell Biol (1986) 4.07
Pharmacotherapy of Alzheimer's disease: is there a need to redefine treatment success? Int J Geriatr Psychiatry (2001) 3.09
Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis. J Biol Chem (1991) 2.89
Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons. J Neurophysiol (1998) 2.52
Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling. J Exp Med (1994) 2.26
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat Cell Biol (1999) 2.14
Structure and function of Syk protein-tyrosine kinase. J Biochem (2001) 2.09
Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation. Genes Cells (2000) 2.05
The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation. Dev Biol (1998) 2.04
Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth. Nat Cell Biol (2001) 1.95
Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc Natl Acad Sci U S A (1992) 1.76
The dilute-lethal (dl) gene attacks a Ca2+ store in the dendritic spine of Purkinje cells in mice. Neurosci Lett (1996) 1.69
Cytomegalovirus DNA in the sera of patients with cytomegalovirus pneumonia. Br J Haematol (1991) 1.68
Medial prefrontal cortex generates frontal midline theta rhythm. Neuroreport (1999) 1.64
A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ (2007) 1.63
Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling. J Exp Med (1995) 1.62
Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan. E2020 Study Group. Dement Geriatr Cogn Disord (2001) 1.59
Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration. J Neurosci (2000) 1.59
Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia. Atherosclerosis (1985) 1.55
Ca2+ images and K+ current during depolarization in smooth muscle cells of the guinea-pig vas deferens and urinary bladder. J Physiol (1998) 1.54
Enzymic adenosine diphosphoribosylation of nuclear proteins. Cold Spring Harb Symp Quant Biol (1969) 1.54
A carcinoid tumor of the rectum removed by strip biopsy. Endoscopy (1993) 1.50
Morbidity and mortality of hospitalized patients after the 1995 Hanshin-Awaji earthquake. Am J Emerg Med (1999) 1.47
Reconstitution of interactions between tyrosine kinases and the high affinity IgE receptor which are controlled by receptor clustering. EMBO J (1995) 1.46
Three distinct forms of type 2A protein phosphatase in human erythrocyte cytosol. J Biol Chem (1988) 1.45
Respiratory failure in nemaline myopathy. Pediatr Neurol (1997) 1.43
Analysis of 2,702 traumatized patients in the 1995 Hanshin-Awaji earthquake. J Trauma (1997) 1.43
Nuclear genes coding the yeast mitochondrial adenosine triphosphatase complex. Primary sequence analysis of ATP2 encoding the F1-ATPase beta-subunit precursor. J Biol Chem (1985) 1.42
Variable Bcl-2 phenotype in benign and malignant lesions of urothelium. Cancer Lett (1998) 1.42
Protein chain initiation and deformylation in B. subtilis homogenates. Proc Natl Acad Sci U S A (1968) 1.41
Follow-up study on histogenesis of microcephaly associated with ectopic gray matter induced by prenatal gamma-irradiation in the mouse. J Neuropathol Exp Neurol (1996) 1.41
Antiulcer activity of dehydroabietic acid derivatives. Chem Pharm Bull (Tokyo) (1985) 1.40
Subcutaneous administration of recombinant human erythropoietin before cardiac surgery: a double-blind, multicenter trial in Japan. Transfusion (1994) 1.39
Analysis of 372 patients with Crush syndrome caused by the Hanshin-Awaji earthquake. J Trauma (1997) 1.39
[Minimal incision cardiac surgery for atrial septal defects]. J Cardiol (2000) 1.38
Death by influenza virus protein. Nat Med (2001) 1.36
Adenosine 3':5'-monophosphate-dependent protein kinase from yeast. J Biol Chem (1974) 1.35
Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system. Genes Cells (1999) 1.35
Local Ca(2+) transients and distribution of BK channels and ryanodine receptors in smooth muscle cells of guinea-pig vas deferens and urinary bladder. J Physiol (2001) 1.35
Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer. Br J Cancer (2011) 1.32
Effect of a new potent H2-blocker, 3-]]]2-[(diaminomethylene)amino]-4-thiazolyl]methyl]-thio]-N2-sulfamoylpropionamidine (YM-11170) on gastric secretion induced by histamine and food in conscious dogs. Arch Int Pharmacodyn Ther (1982) 1.32
Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain. J Biol Chem (2000) 1.31
SP-40,40 is a constituent of Alzheimer's amyloid. Acta Neuropathol (1992) 1.30
A young type III hyperlipoproteinemic patient associated with apolipoprotein E deficiency. Metabolism (1989) 1.28
Mechanisms for ovariectomy-induced hyperalgesia and its relief by calcitonin: participation of 5-HT1A-like receptor on C-afferent terminals in substantia gelatinosa of the rat spinal cord. J Neurosci (2000) 1.28
Phosphorylation of smg p21, a ras p21-like GTP-binding protein, by cyclic AMP-dependent protein kinase in a cell-free system and in response to prostaglandin E1 in intact human platelets. J Biol Chem (1989) 1.27
A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity. Oncogene (2000) 1.26
Neuroaxonal dystrophy. A case of delayed onset and protracted course. Acta Neuropathol (1971) 1.24
Telomere shortening in peripheral blood cells was related with aging but not with white blood cell count. Jpn J Hum Genet (1996) 1.24
Association with B-cell-antigen receptor with protein-tyrosine kinase p72syk and activation by engagement of membrane IgM. Eur J Biochem (1993) 1.22
Epidermoid cyst of the penis: a case report and review of the literature. Int J Urol (2000) 1.21
Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations. J Biol Chem (2001) 1.21
Endoplasmic reticulum is missing in dendritic spines of Purkinje cells of the ataxic mutant rat. Brain Res (1996) 1.21
A novel Drosophila receptor tyrosine kinase expressed specifically in the nervous system. Unique structural features and implication in developmental signaling. J Biol Chem (1997) 1.21
syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction. Proc Natl Acad Sci U S A (1997) 1.20
Foot protein isoforms are expressed at different times during embryonic chick skeletal muscle development. J Cell Biol (1991) 1.20
Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway. Immunity (1995) 1.19
Thrombin and collagen induce rapid phosphorylation of a common set of cellular proteins on tyrosine in human platelets. J Biol Chem (1989) 1.19
Measurement and simulation of noninactivating Ca current in smooth muscle cells. Am J Physiol (1989) 1.19
Syk expression and novel function in a wide variety of tissues. Biochem Biophys Res Commun (2001) 1.18
Brachytherapy for stage I & II oral tongue cancer: an analysis of past cases focusing on control and complications. Int J Radiat Oncol Biol Phys (1993) 1.17
A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment. Mech Dev (1998) 1.16
Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts. J Biol Chem (1996) 1.16
A requirement for Syk in the activation of the microtubule-associated protein kinase/phospholipase A2 pathway by Fc epsilon R1 is not shared by a G protein-coupled receptor. J Biol Chem (1995) 1.16
Mechanism of membrane damage induced by the amphipathic peptides gramicidin S and melittin. Biochim Biophys Acta (1989) 1.16
Resolution and reassociation of three distinct components from pig heart phosphoprotein phosphatase. J Biol Chem (1983) 1.15
Laparoscopic adrenalectomy for primary aldosteronism: a new operative method. J Laparoendosc Surg (1993) 1.14
Measles virus receptors. Curr Top Microbiol Immunol (2009) 1.14
Virus identification in cytologic and histologic material by electron microscopy. Acta Cytol (1969) 1.14
Activation of protein phosphatase 2A by cAMP-dependent protein kinase-catalyzed phosphorylation of the 74-kDa B'' (delta) regulatory subunit in vitro and identification of the phosphorylation sites. FEBS Lett (1998) 1.14
Solubilization and separation of the glucagon receptor and adenylate cyclase in guanine nucleotide-sensitive states. J Biol Chem (1977) 1.14
Mode of action of adenosine 3',5'-cyclic phosphate on protein kinase from rat liver. Biochem Biophys Res Commun (1970) 1.13
Role of tyrosine phosphorylation of HS1 in B cell antigen receptor-mediated apoptosis. J Exp Med (1997) 1.13
Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products. Biochem Biophys Res Commun (1988) 1.13
Morphological classification of retinal ganglion cells in mice. J Comp Neurol (1995) 1.12
Protein-tyrosine kinase p72syk is activated by thrombin and is negatively regulated through Ca2+ mobilization in platelets. J Biol Chem (1993) 1.12
Oral malignant melanoma in Japan. Oral Surg Oral Med Oral Pathol (1994) 1.12
Values of carcinoembryonic antigen, elastase 1, and carbohydrate antigen determinant in aspirated pancreatic cystic fluid in the diagnosis of cysts of the pancreas. Cancer (1986) 1.11
Histochemical, lectin-histochemical and morphometrical characteristics of intestinal goblet cells of germfree and conventional mice. Exp Anim (1996) 1.11
Mice lacking smooth muscle calponin display increased bone formation that is associated with enhancement of bone morphogenetic protein responses. Genes Cells (1998) 1.11
Tofogliflozin, a novel sodium-glucose co-transporter 2 inhibitor, improves renal and pancreatic function in db/db mice. Br J Pharmacol (2013) 1.10
In vivo imaging of spontaneous ultraweak photon emission from a rat's brain correlated with cerebral energy metabolism and oxidative stress. Neurosci Res (1999) 1.10
The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid beta protein. J Biol Chem (1999) 1.10
Detection of hepatitis B virus DNA in paraffin-embedded liver tissues in chronic hepatitis B or non-A, non-B, hepatitis using the polymerase chain reaction. Hepatology (1991) 1.10
Molecular cloning of a 74-kDa regulatory subunit (B" or delta) of human protein phosphatase 2A. FEBS Lett (1996) 1.09
Pharmacological evidence of distinct alpha 1-adrenoceptor subtypes mediating the contraction of human prostatic urethra and peripheral artery. Br J Pharmacol (1994) 1.09
Evidence that a phosphatidylinositol 3,4,5-trisphosphate-binding protein can function in nucleus. J Biol Chem (1999) 1.08
Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. Diabetologia (1997) 1.07
Survey of complications of indocyanine green angiography in Japan. Am J Ophthalmol (1994) 1.07
Assembly and exchange of intermediate filament proteins of neurons: neurofilaments are dynamic structures. J Cell Biol (1989) 1.06
Metabolism of phosphoric acid triesters by rat liver homogenate. Bull Environ Contam Toxicol (1984) 1.05
Studies on the sites in histones phosphorylated by adenosine 3':5'-monophosphate-dependent and guanosine 3':5'-monophosphate-dependent protein kinases. J Biol Chem (1976) 1.05
A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics (1996) 1.03
Antiulcer activities of glycyrrhetinic acid derivatives in experimental gastric lesion models. Chem Pharm Bull (Tokyo) (1989) 1.03