Published in J Mol Biol on March 14, 1968
The determination of the molecular weight of ribonucleic acid by polyacrylamide-gel electrophresis. The effects of changes in conformation. Biochem J (1969) 9.68
The regulation of RNA synthesis and processing in the nucleolus during inhibition of protein synthesis. J Cell Biol (1969) 2.13
The selective interruption of nucleolar RNA synthesis in HeLa cells by cordycepin. J Cell Biol (1969) 1.77
Nucleolar-derived ribonucleic acid in chromosomes, nuclear sap, and cytoplasm of Chironomus tentans salivary gland cells. J Cell Biol (1971) 1.51
Evolution of the transcription unit of ribosomal RNA. Proc Natl Acad Sci U S A (1970) 1.49
Cytoplasmic synthesis of nuclear proteins. Kinetics of accumulation of radioactive proteins in various cell fractions after brief pulses. J Cell Biol (1971) 1.29
The cytoplasmic RNA of HeLa cells: new discrete species associated with mitochondria. Proc Natl Acad Sci U S A (1969) 1.10
The oestrogen-stimulated synthesis of heterogeneous nuclear ribonucleic acid in the uterus of immature rats. Biochem J (1973) 1.01
Metabolism of ribosomal precursor ribonucleic acid in kidney. J Cell Biol (1970) 0.99
The pseudouridine contents of the ribosomal ribonucleic acids of three vertebrate species. Numerical correspondence between pseudouridine residues and 2'-O-methyl groups is not always conserved. Biochem J (1978) 0.98
Synthesis and maturation of ribosomal ribonucleic acids in isolated HeLa cell nuclei. A tracer study on the topology of the 45S precursor of ribosomal ribonucleic acids. Biochem J (1974) 0.88
Reaction of HeLa cell methyl-labelled 28S ribosomal RNA with sodium bisulphite: a conformational probe for methylated sequences. Nucleic Acids Res (1976) 0.85
Isolation and biochemical characterization of nuclei from chick embryo liver. J Cell Biol (1971) 0.78
Methylation of newly synthesized ribonucleic acid by isolated rat liver nuclei. Characterization of the ribonucleic acid synthesized by nuclei from starved animals. Biochem J (1971) 0.75
A spectrophotometric study of the secondary structure of precursor ribosomal ribonucleic acid from Krebs ascites-tumour cells. Biochem J (1973) 0.75
Methylation of newly synthesized ribonucleic acid by isolated rat liver nuclei: a means of characterizing ribonucleic acid synthesized in vitro. Biochem J (1971) 0.75
RNA metabolism in the HeLa cell nucleus. J Mol Biol (1966) 17.11
Medicine prices, availability, and affordability in 36 developing and middle-income countries: a secondary analysis. Lancet (2008) 11.56
Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax (2003) 9.54
Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cells. J Mol Biol (1968) 6.19
Hunger, waiting time and transport costs: time to confront challenges to ART adherence in Africa. AIDS Care (2007) 6.09
The marketplace in health care reform. The demographic limitations of managed competition. N Engl J Med (1993) 5.90
Randomised trial of monitoring, feedback, and management of care by telephone to improve treatment of depression in primary care. BMJ (2000) 5.45
Small RNA species of the HeLa cell: metabolism and subcellular localization. Cell (1976) 5.27
A cytoskeletal structure with associated polyribosomes obtained from HeLa cells. Cell (1977) 5.22
Acrylamide gel electrophoresis of HeLa cell nucleolar RNA. Proc Natl Acad Sci U S A (1967) 5.06
Small molecular weight monodisperse nuclear RNA. J Mol Biol (1968) 4.96
Effects on host cell metabolism following synchronous infection with poliovirus. Virology (1965) 4.88
Community-level comparisons between the grocery store environment and individual dietary practices. Prev Med (1991) 4.45
Ribosomal RNA synthesis and processing in a particulate site in the HeLa cell nucleus. Science (1966) 4.43
Messenger RNA in HeLa cells: kinetics of formation and decay. J Mol Biol (1973) 4.39
Messenger RNA is translated when associated with the cytoskeletal framework in normal and VSV-infected HeLa cells. Cell (1981) 4.34
Regulation of protein synthesis in mammalian cells. II. Inhibition of protein synthesis at the level of initiation during mitosis. J Mol Biol (1970) 3.98
Selective inhibition of the synthesis of mitochondria-associated RNA by ethidium bromide. J Mol Biol (1969) 3.91
The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy. J Cell Biol (1986) 3.90
Core filaments of the nuclear matrix. J Cell Biol (1990) 3.69
Messenger and heterogeneous nuclear RNA in HeLa cells: differential inhibition by cordycepin. Proc Natl Acad Sci U S A (1970) 3.67
The outer boundary of the cytoskeleton: a lamina derived from plasma membrane proteins. Cell (1979) 3.66
The nuclear matrix: three-dimensional architecture and protein composition. Cell (1982) 3.51
Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition. J Cell Biol (1984) 3.48
Messenger RNA in heat-shocked Drosophila cells. J Mol Biol (1977) 3.25
Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci U S A (2000) 3.24
The solvent denaturation of double-stranded RNA from poliovirus infected HeLa cells. Biochem Biophys Res Commun (1966) 3.21
Mechanisms of regulating tubulin synthesis in cultured mammalian cells. Cell (1979) 3.19
The metabolism of a poly(A) minus mRNA fraction in HeLa cells. Cell (1974) 3.17
Products of RNA polymerases in HeLa cell nuclei. Proc Natl Acad Sci U S A (1971) 3.02
Association of nuclear matrix antigens with exon-containing splicing complexes. J Cell Biol (1994) 3.01
Age-related changes in cortical blood flow activation during visual processing of faces and location. J Neurosci (1994) 2.92
PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther (1999) 2.90
The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J Biol Chem (1994) 2.84
Protein synthesis requires cell-surface contact while nuclear events respond to cell shape in anchorage-dependent fibroblasts. Cell (1980) 2.80
Regulation of protein synthesis in HeLa cells. 3. Inhibition during poliovirus infection. J Virol (1971) 2.80
Regulation of protein synthesis in HeLa cells: translation at elevated temperatures. J Mol Biol (1969) 2.79
The cytoskeletal framework and poliovirus metabolism. Cell (1979) 2.73
Association of the src gene product of Rous sarcoma virus with cytoskeletal structures of chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1980) 2.63
Processing of 45 s nucleolar RNA. J Mol Biol (1970) 2.60
The messenger RNA sequences in growing and resting mouse fibroblasts. Cell (1975) 2.53
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. J Clin Invest (1997) 2.48
Stability of HeLa cell mRNA in actinomycin. Nature (1972) 2.47
Analysis of drosophila mRNA by in situ hybridization: sequences transcribed in normal and heat shocked cultured cells. Cell (1975) 2.43
Differences in sociodemographic, health status, and lifestyle characteristics among American Indians by telephone coverage. Prev Med (1994) 2.37
Transcription of the adenovirus genome by an -amanitine-sensitive ribonucleic acid polymerase in HeLa cells. J Virol (1972) 2.29
The mechanism of host cell protein synthesis inhibition by poliovirus. Virology (1966) 2.20
The control of mRNA production, translation and turnover in suspended and reattached anchorage-dependent fibroblasts. Cell (1978) 2.19
Electron microscopic studies of detergent-treated HeLa cell nuclei. J Mol Biol (1966) 2.19
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther (1998) 2.19
Design and gene delivery activity of modified polyethylenimines. Adv Drug Deliv Rev (2001) 2.18
Poliovirus-induced inhibition of polypeptide initiation in vitro on native polyribosomes. Proc Natl Acad Sci U S A (1976) 2.15
Heterogeneous nuclear RNA-protein fibers in chromatin-depleted nuclei. J Cell Biol (1978) 2.14
Distressed high utilizers of medical care. DSM-III-R diagnoses and treatment needs. Gen Hosp Psychiatry (1990) 2.13
The regulation of RNA synthesis and processing in the nucleolus during inhibition of protein synthesis. J Cell Biol (1969) 2.13
Membrane-associated protein synthesis of mammalian cells. I. The two classes of membrane-associated ribosomes. J Mol Biol (1971) 2.09
Frustrating patients: physician and patient perspectives among distressed high users of medical services. J Gen Intern Med (1991) 2.08
The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proc Natl Acad Sci U S A (1994) 2.06
A distinct RNA polymerase activity, synthesizing 5-5 s, 5 s and 4 s RNA in nuclei from adenovirus 2-infected HeLa cells. J Mol Biol (1972) 2.06
Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors. Proc Natl Acad Sci U S A (1997) 2.06
The spatial distribution of polyribosomes in 3T3 cells and the associated assembly of proteins into the skeletal framework. Cell (1980) 2.00
A randomized trial of psychiatric consultation with distressed high utilizers. Gen Hosp Psychiatry (1992) 2.00
The relation of protein synthesis regulation and RNA metabolism. Acta Endocrinol Suppl (Copenh) (1973) 1.92
Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus. Gene Ther (2000) 1.90
High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. Proc Natl Acad Sci U S A (1992) 1.90
Subnuclear particles containing a small nuclear RNA and heterogeneous nuclear RNA. J Mol Biol (1981) 1.90
Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Hum Gene Ther (1996) 1.87
Regulation of actin mRNA levels and translation responds to changes in cell configuration. Mol Cell Biol (1983) 1.86
Adenovirus enhancement of transferrin-polylysine-mediated gene delivery. Proc Natl Acad Sci U S A (1991) 1.85
Nuclear matrix proteins reflect cell type of origin in cultured human cells. Proc Natl Acad Sci U S A (1988) 1.85
Chromatin architecture and nuclear RNA. Proc Natl Acad Sci U S A (1989) 1.82
Altered translatability of messenger RNA from suspended anchorage-dependent fibroblasts: reversal upon cell attachment to a surface. Cell (1978) 1.82
Association by hydrogen bonding of free nucleosides in non-aqueous solution. J Mol Biol (1966) 1.81
Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. Proc Natl Acad Sci U S A (1990) 1.79
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J Gene Med (2001) 1.78
The selective interruption of nucleolar RNA synthesis in HeLa cells by cordycepin. J Cell Biol (1969) 1.77
Environmental indicators: a tool for evaluating community-based health-promotion programs. Am J Prev Med (1993) 1.76
The metabolism of poly (A)+ and poly(A)-hnRNA in cultured Drosophila cells studied with a rapid uridine pulse-chase. Cell (1977) 1.76
Mitochondrial protein synthesis: resistance to emetine and response to RNA synthesis inhibitors. Biochem Biophys Res Commun (1970) 1.74
Cytochalasin releases mRNA from the cytoskeletal framework and inhibits protein synthesis. Mol Cell Biol (1986) 1.74
An RGD-oligolysine peptide: a prototype construct for integrin-mediated gene delivery. Hum Gene Ther (1998) 1.73
Visualizing gene expression by whole-body fluorescence imaging. Proc Natl Acad Sci U S A (2000) 1.72
Membrane-bound polyribosomes in HeLa cells: association of polyadenylic acid with membranes. J Mol Biol (1974) 1.70
Effect of bronchial smooth muscle contraction on lung compliance. J Appl Physiol (1985) (1992) 1.68
Coronary disease severity and functional impairment: how strong is the relation? J Am Geriatr Soc (1996) 1.66
DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression. AAPS PharmSci (2001) 1.66
A new method of preparing embeddment-free sections for transmission electron microscopy: applications to the cytoskeletal framework and other three-dimensional networks. J Cell Biol (1984) 1.65
Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells. Proc Natl Acad Sci U S A (1990) 1.64
The architectural organization of nuclear metabolism. Int Rev Cytol (1995) 1.63
An opportunistic infection with Corynebacterium pyogenes producing empyema. Am J Clin Pathol (1970) 1.62
The effect of high ionic strength on monomers, polyribosomes, and puromycin-treated polyribosomes. Biochim Biophys Acta (1970) 1.61
Regulation of protein synthesis in mammalian cells. V. Further studies on the effect of actinomycin D on translation control in HeLa cells. J Mol Biol (1973) 1.61
Do communities differ in health behaviors? J Clin Epidemiol (1993) 1.60
Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells. Cell (1975) 1.59
Progressive loss of shape-responsive metabolic controls in cells with increasingly transformed phenotype. Cell (1981) 1.59
Spatial-temporal imaging of bacterial infection and antibiotic response in intact animals. Proc Natl Acad Sci U S A (2001) 1.59
Gene therapy progress and prospects: synthetic polymer-based systems. Gene Ther (2008) 1.58