Published in J Exp Med on May 01, 1968
Role of antibody and complement in the immune clearance and destruction of erythrocytes. I. In vivo effects of IgG and IgM complement-fixing sites. J Clin Invest (1972) 2.82
Selective roles of thymus-derived lymphocytes in the antibody response. I. Differential suppressive effect of carrier-primed T cells on hapten-specific IgM and IgG antibody responses. J Exp Med (1974) 2.50
The effect of temperature on the reactivity of guinea-pig complement with gamma G and gamma M haemolytic antibodies. Immunology (1970) 2.14
Evidence that rabbit gamma G haemolysin in capable of utilizing guinea-pig complement more efficiently than rabbit gamma M haemolysin. Immunology (1970) 1.48
Selective roles of thymus-derived lymphocytes in the antibody response. II. Preferential suppression of high-affinity antibody-forming cells by carrier-primed suppressor T cells. J Exp Med (1974) 1.46
Characterization of immunoglobulin structures from the surface of chronic lymphocytic leukemia cells. J Exp Med (1971) 1.12
Ultrastructure of papain and pepsin digestion fragments of human IgM globulins. J Exp Med (1969) 1.08
Individual antigenic specificity of human macroglobulins: Localization of antigenic determinants and their use to demonstrate formation of hybrid molecules after reduction and reassociation. J Exp Med (1969) 1.04
Truncated mu (mu') chains in murine IgM. Evidence that mu' chains lack variable regions. J Exp Med (1985) 0.89
Observations on the reactions between D-positive red cells and ( 125 I)IgM anti-D molecules and subunits. Immunology (1971) 0.86
Spontaneous re-aggregation of IgM subunits and restoration of antibody activity after reduction and alkylation of rabbit anti-Forssman antibody. Immunology (1969) 0.85
Dissociation of human serum macroglobulins. Science (1957) 10.94
SINGLE CELL STUDIES ON 19S ANTIBODY PRODUCTION. J Exp Med (1964) 6.32
CHARACTERIZATION OF A HUMAN MACROGLOBULIN. I. THE MOLECULAR WEIGHT OF ITS SUBUNIT. J Biol Chem (1965) 4.37
The proliferative capacity of antigen-sensitive precursors of hemolytic plaque-forming cells. J Immunol (1966) 3.07
ACTIVITY OF DISSOCIATED AND REASSOCIATED 19S ANTI-GAMMA-GLOBULINS. J Exp Med (1964) 2.29
Number of binding sites of rabbit macroglobulin antibody and its subunits. Immunochemistry (1965) 2.16
Applications of radioactively labeled marker proteins in density gradient ultracentrifugation. Anal Biochem (1963) 2.06
Polypeptide chain structure of rabbit immunoglobulins. II. gamma-M-immunoglobulin. Biochemistry (1966) 1.84
THE REACTION WITH RED CELLS OF 7S RABBIT ANTIBODY, ITS SUB-UNITS AND THEIR RECOMBINANTS. Immunology (1965) 1.79
THE SUBUNITS OF PURIFIED RABBIT ANTIBODY. Biochemistry (1964) 1.77
Characterization of a human macroglobulin. 3. The products of tryptic digestion. J Biol Chem (1966) 1.72
Dissociation, reaggregation, and subunit structure studies of some human gamma-M-globulins. J Biol Chem (1967) 1.64
The effect of repeated injections of sheep red cells on the hemolytic and combining capacities of rabbit antiserums. J Infect Dis (1956) 1.51
Kinetic studies on immune hemolysis. II. The reversibility of red cell-antibody combination and the resultant transfer of antibody from cell to cell during hemolysis. J Exp Med (1951) 1.10
Studies on human antibodies. IV. Purification and properties of anti-A and anti-B obtained by absorption and elution from insoluble blood group substances. J Exp Med (1966) 1.09
Horse anti-SI immunoglobulins. I. Properties of gamma-M-antibody. Biochemistry (1965) 1.03
Occurrence and properties of a macroglobulin dimer in some hyperglobulinemic sera. J Exp Med (1966) 0.94
Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. N Engl J Med (1979) 4.52
The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells. Bull World Health Organ (1972) 4.25
Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis. J Clin Invest (1977) 4.21
Treatment of hereditary angioedema with a vapor-heated C1 inhibitor concentrate. N Engl J Med (1996) 3.89
Sjögren's syndrome (Sicca syndrome): current issues. Ann Intern Med (1980) 3.81
Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell lines. J Clin Invest (1972) 3.64
The follicular dendritic cell: its role in antigen presentation in the generation of immunological memory. Immunol Rev (1980) 3.53
The role of the classical and alternate complement pathways in host defenses against Cryptococcus neoformans infection. J Immunol (1974) 3.38
Hereditary angioedema: the clinical syndrome and its management. Ann Intern Med (1976) 3.10
The localization of antigen in relation to specific antibody-producing cells. I. Use of a synthetic polypeptide [(T,G)-A--L] labelled with iodine-125. Immunology (1966) 3.09
Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils. J Immunol (1985) 3.02
Treatment of hereditary angioedema with danazol. Reversal of clinical and biochemical abnormalities. N Engl J Med (1976) 2.96
Human neutrophils increase expression of C3bi as well as C3b receptors upon activation. J Clin Invest (1984) 2.88
Role of antibody and complement in the immune clearance and destruction of erythrocytes. I. In vivo effects of IgG and IgM complement-fixing sites. J Clin Invest (1972) 2.82
The lesions in cell membranes caused by complement. Adv Immunol (1969) 2.81
Receptors for immunoglobulin and complement on human alveolar macrophages. J Immunol (1975) 2.74
Correlation of grain counts with radioactivity (125I and tritium) in autoradiography. Exp Cell Res (1966) 2.62
A new one-step method for the functional assay of the fourth component (C4) of human and guinea pig complement. J Immunol (1974) 2.60
Kinetic analysis of chemotactic factor generation in human serum via activation of the classical and alternate complement pathways. Clin Immunol Immunopathol (1975) 2.56
Inhibition of the complement cascade by the major secretory protein of vaccinia virus. Science (1990) 2.49
Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes. J Exp Med (1983) 2.49
Bactericidal and opsonic properties of C4-deficient guinea pig serum. J Immunol (1972) 2.48
Different macrophage populations distinguished by means of fluorescent polysaccharides. Recognition and properties of marginal-zone macrophages. Eur J Immunol (1981) 2.47
A receptor for the third component of complement in the human renal glomerulus. J Exp Med (1975) 2.39
A quantitative analysis of the interactions of antipneumococcal antibody and complement in experimental pneumococcal bacteremia. J Clin Invest (1982) 2.33
In vitro studies of complement function in sera of C4-deficient guinea pigs. J Exp Med (1971) 2.29
Impaired immune response of splenectomised patients to polyvalent pneumococcal vaccine. Lancet (1981) 2.29
Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors. J Immunol (1986) 2.28
Nodular lymphoma--evidence for origin from follicular B lymphocytes. N Engl J Med (1974) 2.26
Defective Fc-receptor functions associated with the HLA-B8/DRw3 haplotype: studies in patients with dermatitis herpetiformis and normal subjects. N Engl J Med (1981) 2.19
Complement component C3b binds directly to purified glycoprotein C of herpes simplex virus types 1 and 2. Microb Pathog (1987) 2.15
Inhibition of secondary anti-hapten responses with the hapten conjugated to type 3 pneumococcal polysaccharide. Eur J Immunol (1972) 2.14
The effect of temperature on the reactivity of guinea-pig complement with gamma G and gamma M haemolytic antibodies. Immunology (1970) 2.14
Characterization of C1q receptor expression on human phagocytic cells: effects of PDBu and fMLP. J Immunol (1986) 2.09
Systemic capillary leak syndrome and monoclonal IgG gammopathy; studies in a sixth patient and a review of the literature. Medicine (Baltimore) (1977) 2.07
Problems in leishmaniasis related to immunology. Curr Top Microbiol Immunol (1969) 2.07
The localization of non-microbial antigens in the draining lymph nodes of tolerant, normal and primed rabbits. Immunology (1967) 2.07
Aerosol alpha 1-antitrypsin treatment for cystic fibrosis. Lancet (1991) 2.05
Ontogeny of B lymphocytes. II. Relative rates of appearance of lymphocytes bearing surface immunoglobulin and complement receptors. J Exp Med (1974) 2.03
Studies of the molecular mechanisms of C3b inactivation and a simplified assay of beta 1H and the C3b inactivator (C3bINA). J Immunol (1979) 2.01
In vivo studies in C4-deficient guinea pigs. J Exp Med (1971) 2.00
Complement and bacteria: chemistry and biology in host defense. Annu Rev Immunol (1984) 1.87
The critical role of complement in experimental pneumococcal sepsis. J Infect Dis (1980) 1.87
Haemolytic efficiency of rabbit IgG anti-Forssman antibody and its augmentation by anti-rabbit IgG. Nature (1967) 1.83
Role of antibody and complement in the immune clearance and destruction of erythrocytes. II. Molecular nature of IgG and IgM complement-fixing sites and effects of their interaction with serum. J Clin Invest (1972) 1.82
Complement depletion in cryptococcal sepsis. J Immunol (1978) 1.82
The complement system in host defense and inflammation. Rev Infect Dis (1980) 1.80
NIH Conference: Immunoglobulin G Fc receptor-mediated clearance in autoimmune diseases. Ann Intern Med (1983) 1.79
Specific inhibition of the Prausnitz-Küstner reaction by an atypical human myeloma protein. Lancet (1967) 1.76
A new complement-mediated cytolytic mechanism--the C1-bypass activation pathway. Proc Natl Acad Sci U S A (1973) 1.74
Large mononuclear (veiled) cells like 'Ia-like' membrane antigens in human afferent lympn. Clin Exp Immunol (1980) 1.74
C3b covalently bound to IgG demonstrates a reduced rate of inactivation by factors H and I. J Exp Med (1984) 1.74
Epsilon aminocaproic acid therapy of hereditary angioneurotic edema. A double-blind study. N Engl J Med (1972) 1.73
Glycoprotein C of herpes simplex virus 1 is an inhibitor of the complement cascade. J Immunol (1986) 1.72
C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alpha. J Exp Med (1988) 1.67
Opsonic requirements for intravascular clearance after splenectomy. N Engl J Med (1981) 1.65
Hereditary deficiency of the sixth component of complement in man. I. Immunochemical, biologic, and family studies. J Clin Invest (1974) 1.65
Generation of isogenic K54 capsule-deficient Escherichia coli strains through TnphoA-mediated gene disruption. Mol Microbiol (1993) 1.63
The role of antibody and complement in the reticuloendothelial clearance of pneumococci from the bloodstream. Rev Infect Dis (1983) 1.63
A simple method for the determination of complement receptor-bearing mononuclear cells. J Immunol (1976) 1.59
Capsule production and growth phase influence binding of complement to Staphylococcus aureus. Infect Immun (2001) 1.59
The generation of memory cells. I. The role of C3 in the generation of B memory cells. Immunology (1977) 1.59
The effect of Bacillus Calmette-Guerin-induced macrophage activation on the in vivo clearance of sensitized erythrocytes. J Clin Invest (1974) 1.58
Response of variant hereditary angioedema phenotypes to danazol therapy. Genetic implications. J Clin Invest (1979) 1.58
Immune lysis of normal human and paroxysmal nocturnal hemoglobinuria (PNH) red blood cells. 3. The membrane defects caused by complement lysis. J Exp Med (1966) 1.57
Acquired C1 esterase inhibitor deficiency and angioedema: a review. Medicine (Baltimore) (1979) 1.57
Lack of binding of human C3, in its native state, to C3b receptors. J Immunol (1981) 1.57
Splenic dependence of the antibody response to thymus-independent (TI-2) antigens. Eur J Immunol (1985) 1.56
The origin of follicular dendritic cells in the mouse and the mechanism of trapping of immune complexes on them. Eur J Immunol (1984) 1.55
Studies on the in vivo effects of antibody. Interaction of IgM antibody and complement in the immune clearance and destruction of erythrocytes in man. J Clin Invest (1974) 1.54
Tolerogenic or immunogenic activity of hapten-conjugated polysaccharides correlated with cellular localization. Eur J Immunol (1981) 1.52
Modulation of FcR function by complement: subcomponent C1q enhances the phagocytosis of IgG-opsonized targets by human monocytes and culture-derived macrophages. J Immunol (1987) 1.51
Concern Molecular composition of complement-solubilized complexes and their fate in vivo. Immunology (1983) 1.49
Regulation of complement activity by vaccinia virus complement-control protein. J Infect Dis (1992) 1.49
Studies on the fibronectin receptors of human peripheral blood leukocytes. Morphologic and functional characterization. J Exp Med (1984) 1.48
Evidence that rabbit gamma G haemolysin in capable of utilizing guinea-pig complement more efficiently than rabbit gamma M haemolysin. Immunology (1970) 1.48
Demonstration of circulating immune complexes in Sjögren's syndrome. J Immunol (1979) 1.46
Role of complement in host defense against experimental disseminated candidiasis. J Infect Dis (1978) 1.46
Receptor specific clearance by the reticuloendothelial system in chronic liver diseases. Demonstration of defective C3b-specific clearance in primary biliary cirrhosis. J Clin Invest (1978) 1.45
Prolonged C3 depletion by cobra venom factor in thymus-deprived mice and its implication for the role of C3 as an essential second signal for B-cell triggering. Immunology (1975) 1.44
Deficiency of the homologous restriction factor in paroxysmal nocturnal hemoglobinuria. J Exp Med (1987) 1.44
Mechanism of bacterial resistance to complement-mediated killing: inserted C5b-9 correlates with killing for Escherichia coli O111B4 varying in O-antigen capsule and O-polysaccharide coverage of lipid A core oligosaccharide. Infect Immun (1984) 1.42
C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma. J Immunol (1987) 1.41
The role of complement in the clearance of cold agglutinin-sensitized erythrocytes in man. J Clin Invest (1976) 1.40
Vitamin A supplementation in malnourished Sudanese children. Int J Vitam Nutr Res (1992) 1.40
The role of late complement components and the alternate complement pathway in experimental cryptococcosis. Proc Soc Exp Biol Med (1973) 1.38
The glomerular complement receptor in immunologically mediated renal glomerular injury. N Engl J Med (1976) 1.38
Leukemic reticuloendotheliosis: presence of a receptor for cytophilic antibody. Am J Med (1974) 1.37
The fourth component of complement in the cerebrospinal fluid in systemic Lupus erythematosus. Arthritis Rheum (1973) 1.37
Synthetic antigens composed exclusively of L- or D- amino acids. II. Effect of optical configuration on the metabolism and fate of synthetic polypeptide antigens in mice. Immunology (1968) 1.37
Complement receptors. Clin Immunol Rev (1983) 1.37
Complement-mediated tissue damage: contribution of the classical and alternate complement pathways in the Forssman reaction. J Immunol (1972) 1.35
Mechanism of action of blocking immunoglobulin G for Neisseria gonorrhoeae. J Clin Invest (1985) 1.35
Mechanisms involved in elimination of organisms from experimental cutaneous Candida albicans infections in guinea pigs. J Immunol (1976) 1.35
The immunological properties of haptens coupled to thymus-independent carrier molecules. I. The characteristics of the immune response to dinitrophenyl-lysine-substituted pneumococcal polysaccharide (SIII) and levan. Eur J Immunol (1974) 1.35