Published in Biochem Biophys Res Commun on March 10, 1969
The statistical analysis of enzyme kinetic data. Adv Enzymol Relat Areas Mol Biol (1967) 9.95
Statistical analysis of enzyme kinetic data. Methods Enzymol (1979) 9.49
Partition analysis and the concept of net rate constants as tools in enzyme kinetics. Biochemistry (1975) 2.69
Determining the chemical mechanisms of enzyme-catalyzed reactions by kinetic studies. Adv Enzymol Relat Areas Mol Biol (1977) 2.62
Use of multiple isotope effects to determine enzyme mechanisms and intrinsic isotope effects. Malic enzyme and glucose-6-phosphate dehydrogenase. Biochemistry (1982) 2.22
Biotin enzymes. Annu Rev Biochem (1977) 2.04
Stability constants of Mg2+ and Cd2+ complexes of adenine nucleotides and thionucleotides and rate constants for formation and dissociation of MgATP and MgADP. Biochemistry (1984) 2.01
A specific and sensitive assay for disulfides. J Biol Chem (1968) 1.82
The use of pH studies to determine chemical mechanisms of enzyme-catalyzed reactions. Methods Enzymol (1982) 1.76
Isotope exchange studies of the mechanism of the reaction catalyzed by adenosine triphosphate: creatine phosphotransferase. J Biol Chem (1966) 1.55
Purification and kinetic studies of beef liver cytoplasmic aconitase. J Biol Chem (1967) 1.48
Use of isotope effects to elucidate enzyme mechanisms. CRC Crit Rev Biochem (1982) 1.41
Kinetic and chemical mechanisms of yeast formate dehydrogenase. Biochemistry (1980) 1.39
Some physical properties of palmityl-coenzyme A micelles. Biochim Biophys Acta (1968) 1.32
The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. I. Initial velocity, substrate and product inhibition, and isotope exchange studies. J Biol Chem (1974) 1.28
Pigeon liver malic enzyme. V. Kinetic studies. J Biol Chem (1967) 1.25
The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. II. Dead-end and multiple inhibition studies. J Biol Chem (1974) 1.25
Kinetic studies of yeast nucleoside diphosphate kinase. Biochemistry (1969) 1.23
Substrate inhibition. Methods Enzymol (1979) 1.22
Stereoselective preparation of deuterated reduced nicotinamide adenine nucleotides and substrates by enzymatic synthesis. Anal Biochem (1979) 1.21
Mechanistic deductions from isotope effects in multireactant enzyme mechanisms. Biochemistry (1981) 1.21
1-Acylglycerol 3-phosphate acyltransferase from rat liver. J Biol Chem (1969) 1.19
Rat liver pyruvate carboxylase. II. Kinetic studies of the forward reaction. J Biol Chem (1971) 1.16
Influence of salt, substrate, and cofactor concentrations on the kinetic and mechanistic behavior of phosphoglycerate mutase. Biochemistry (1968) 1.15
Secondary deuterium and nitrogen-15 isotope effects in enzyme-catalyzed reactions. Chemical mechanism of liver alcohol dehydrogenase. Biochemistry (1981) 1.15
The inhibition of acetate, pyruvate, and 3-phosphogylcerate kinases by chromium adenosine triphosphate. J Biol Chem (1974) 1.14
Pyruvate carboxylase from chicken liver. Steady state kinetic studies indicate a "two-site" ping-pong mechanism. J Biol Chem (1972) 1.13
Decarboxylation of oxalacetate by pyruvate carboxylase. Biochemistry (1986) 1.13
Kinetic studies of Escherichia coli galactokinase. Biochemistry (1968) 1.13
Bovine liver fructokinase: purification and kinetic properties. Biochemistry (1977) 1.13
Interaction of metal(III)-adenosine 5'-triphosphate complexes with yeast hexokinase. Biochemistry (1980) 1.12
Variation of transition-state structure as a function of the nucleotide in reactions catalyzed by dehydrogenases. 2. Formate dehydrogenase. Biochemistry (1984) 1.12
Fractionation factors and activation energies for exchange of the low barrier hydrogen bonding proton in peptidyl trifluoromethyl ketone complexes of chymotrypsin. Proc Natl Acad Sci U S A (1998) 1.12
pH profiles and isotope effects for aconitases from Saccharomycopsis lipolytica, beef heart, and beef liver. alpha-Methyl-cis-aconitate and threo-Ds-alpha-methylisocitrate as substrates. Biochemistry (1984) 1.11
Relationship of the oxidation state of the iron-sulfur cluster of aconitase to activity and substrate binding. Biochemistry (1981) 1.10
Pyruvate carboxylase: an evaluation of the relationships between structure and mechanism and between structure and catalytic activity. Adv Enzymol Relat Areas Mol Biol (1975) 1.09
Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue. Biochemistry (1982) 1.09
Mechanism of action of the nonspecific phosphomonoesterase from potatoes. Biochemistry (1966) 1.09
Equilibrium perturbation by isotope substitution. Biochemistry (1975) 1.09
Optimizing coupled enzyme assays. Anal Biochem (1979) 1.07
High resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelae. J Biol Chem (2003) 1.07
Determination of the mechanism of orotidine 5'-monophosphate decarboxylase by isotope effects. Biochemistry (2000) 1.06
Fatty acid synthetase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from pigeon liver. J Biol Chem (1975) 1.06
Nitro analogues of citrate and isocitrate as transition-state analogues for aconitase. Biochemistry (1980) 1.05
Rabbit muscle phosphofructokinase. II. Product and dead end inhibition. J Biol Chem (1974) 1.04
pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase. Biochemistry (1981) 1.04
Kinetic mechanism of glutamate dehydrogenase. Biochemistry (1980) 1.04
Derivation of rate equations for multisite ping-pong mechanisms with ping-pong reactions at one or more sites. J Biol Chem (1973) 1.03
Use of pH studies to elucidate the catalytic mechanism of rabbit muscle creatine kinase. Biochemistry (1981) 1.03
Slow-binding inhibition: the general case. Biochim Biophys Acta (1996) 1.03
Transition-state structures for enzymatic and alkaline phosphotriester hydrolysis. Biochemistry (1991) 1.02
Use of nitrogen-15 and deuterium isotope effects to determine the chemical mechanism of phenylalanine ammonia-lyase. Biochemistry (1985) 1.02
Structural properties of pyruvate carboxylases from chicken liver and other sources. Proc Natl Acad Sci U S A (1975) 1.02
Use of multiple isotope effects to study the mechanism of 6-phosphogluconate dehydrogenase. Biochemistry (1984) 1.02
pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same. Biochemistry (1981) 1.02
Studies on the microsomal acylation of L-glycerol-3-phosphate. II. The specificity and properties of the rat liver enzyme. Biochim Biophys Acta (1969) 1.01
Variation of transition-state structure as a function of the nucleotide in reactions catalyzed by dehydrogenases. 1. Liver alcohol dehydrogenase with benzyl alcohol and yeast aldehyde dehydrogenase with benzaldehyde. Biochemistry (1984) 0.98
Mechanisms of enzymatic and acid-catalyzed decarboxylations of prephenate. Biochemistry (1984) 0.98
The use of isotope effects to determine transition-state structure for enzymic reactions. Methods Enzymol (1982) 0.98
The substrate and anomeric specificity of fructokinase. J Biol Chem (1973) 0.98
pH variation of the kinetic parameters and the catalytic mechanism of malic enzyme. Biochemistry (1977) 0.97
Kinetic and isotope-exchange studies on shikimate dehydrogenase from Pisum sativum. Biochemistry (1971) 0.97
Use of primary deuterium and 15N isotope effects to deduce the relative rates of steps in the mechanisms of alanine and glutamate dehydrogenases. Biochemistry (1988) 0.97
Use of isotope effects to deduce the chemical mechanism of fumarase. Biochemistry (1980) 0.97
Use of chromium-adenosine triphosphate and lyxose to elucidate the kinetic mechanism and coordination state of the nucleotide substrate for yeast hexokinase. Biochemistry (1975) 0.96
Meanings of Ki for conventional and alternate-substrate inhibitors. Biochem Pharmacol (1981) 0.96
pH properties and chemical mechanism of action of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Biochemistry (1981) 0.96
Rat liver pyruvate carboxylase. 3. Isotopic exchange studies of the first partial reaction. J Biol Chem (1971) 0.96
Purification and mechanism of action of hog liver mevalonic kinase. J Biol Chem (1970) 0.95
Evidence from nitrogen-15 and solvent deuterium isotope effects on the chemical mechanism of adenosine deaminase. Biochemistry (1987) 0.95
Studies of the microsomal acylation of L-glycerol-3-phosphate. I. The specificity of the rat brain enzyme. Biochim Biophys Acta (1969) 0.95
15N kinetic isotope effects on uncatalyzed and enzymatic deamination of cytidine. Biochemistry (2002) 0.95
Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase. Biochemistry (2001) 0.95
Purification and kinetic studies of the citrate cleavage enzyme. J Biol Chem (1967) 0.94
Kinetics and mechanism of benzoylformate decarboxylase using 13C and solvent deuterium isotope effects on benzoylformate and benzoylformate analogues. Biochemistry (1988) 0.94
Isotope effect studies of the chemical mechanism of pig heart NADP isocitrate dehydrogenase. Biochemistry (1988) 0.94
Pyruvate carboxylase from chicken liver. Effects of univalent and divalent cations on catalytic activity. J Biol Chem (1974) 0.94
Reaction intermediate analogues for enolase. Biochemistry (1984) 0.93
Primary and secondary deuterium isotope effects on equilibrium constants for enzyme-catalyzed reactions. Biochemistry (1980) 0.93
Substrate activity of (adenosine triphosphato)tetraamminecobalt(III) with yeast hexokinase and separation of diastereomers using the enzyme. Biochemistry (1978) 0.93
Response. Science (1995) 0.93
Kinetics of aminoacyl-tRNA synthetases catalyzed ATP-PPi exchange. Methods Enzymol (1974) 0.92
Measurement of isotope effects by the equilibrium perturbation technique. Methods Enzymol (1980) 0.92
Determination of the chemical mechanism of glutamate dehydrogenase from pH studies. Biochemistry (1980) 0.92
Substrate synergism and the kinetic mechanism of yeast hexokinase. Biochemistry (1982) 0.92
Inhibition of creatine kinase by chromium nucleotides. J Biol Chem (1973) 0.91
Identification of the reacting form of pyruvate carboxylase. J Biol Chem (1972) 0.90
Secondary 18O isotope effects for hexokinase-catalyzed phosphoryl transfer from ATP. Biochemistry (1991) 0.90
Role of metal ions in the reaction catalyzed by L-ribulose-5-phosphate 4-epimerase. Biochemistry (2000) 0.90
Use of intermediate partitioning to calculate intrinsic isotope effects for the reaction catalyzed by malic enzyme. Biochemistry (1985) 0.90
pH dependency of the reactions catalyzed by chorismate mutase-prephenate dehydrogenase from Escherichia coli. Biochemistry (1991) 0.90
Photoaffinity labeling and stoichiometry of the coenzyme A ester sites of transcarboxylase. J Biol Chem (1978) 0.89
Studies on the microsomal acylation of L-glycerol-3-phosphate. 3. Time course of the reaction. Biochim Biophys Acta (1969) 0.89
Rabbit muscle phosphofructokinase. I. Anomeric specificity; initial velocity kinetics. J Biol Chem (1974) 0.89
Oxidative decarboxylation of 6-phosphogluconate by 6-phosphogluconate dehydrogenase proceeds by a stepwise mechanism with NADP and APADP as oxidants. Biochemistry (1998) 0.89
Determination of the rate-limiting steps for malic enzyme by the use of isotope effects and other kinetic studies. Biochemistry (1977) 0.88
Preparation and properties of chromium (3)-nucleotide complexes for use in the study of enzyme mechanisms. Biochemistry (1973) 0.88
Determination of the chemical mechanism of malic enzyme by isotope effects. Biochemistry (1997) 0.88