Published in Nihon Ganka Kiyo on March 01, 1969
Homonymous hemioptic hypoplasia. Fundoscopic features in standard and red-free illumination in three patients with congenital hemiplegia. Br J Ophthalmol (1972) 2.03
Fundoscopic appearance of a nerve-fibre-bundle defect. Br J Ophthalmol (1972) 1.18
Atrophy of myelinated nerve fibres in the retina in optic neuritis. Br J Ophthalmol (1975) 0.97
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
Generation of influenza A viruses entirely from cloned cDNAs. Proc Natl Acad Sci U S A (1999) 14.90
Molecular characterization of an enterobacterial metallo beta-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance. Antimicrob Agents Chemother (1994) 8.64
THE ETIOLOGY, MODE OF INFECTION, AND SPECIFIC THERAPY OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1916) 8.21
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature (1998) 7.30
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science (1999) 7.12
PCR detection of metallo-beta-lactamase gene (blaIMP) in gram-negative rods resistant to broad-spectrum beta-lactams. J Clin Microbiol (1996) 6.68
Solid phase synthesis of polynucleotides. VI. Further studies on polystyrene copolymers for the solid support. Nucleic Acids Res (1982) 6.38
A novel integron-like element carrying the metallo-beta-lactamase gene blaIMP. Antimicrob Agents Chemother (1995) 6.00
Chromosomal beta-lactamase of Klebsiella oxytoca, a new class A enzyme that hydrolyzes broad-spectrum beta-lactam antibiotics. Antimicrob Agents Chemother (1989) 5.98
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ (2004) 5.49
Multifocal outbreaks of metallo-beta-lactamase-producing Pseudomonas aeruginosa resistant to broad-spectrum beta-lactams, including carbapenems. Antimicrob Agents Chemother (1996) 5.36
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem (1999) 4.38
PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis (2004) 4.33
THE PROPHYLAXIS OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1916) 4.33
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size. Nat Nanotechnol (2011) 4.22
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature (1988) 3.99
THE RAT AS A CARRIER OF SPIROCHAETA ICTEROHAEMORRHAGIAE, THE CAUSATIVE AGENT OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1917) 3.80
Transcriptional sequencing: A method for DNA sequencing using RNA polymerase. Proc Natl Acad Sci U S A (1998) 3.78
Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide. J Clin Invest (1991) 3.70
Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. Nature (1985) 3.59
THE SERUM TREATMENT OF WEIL'S DISEASE (SPIROCHAETOSIS ICTEROHAEMORRHAGICA). J Exp Med (1916) 3.24
Molecular epidemiologic evidence for association of thermostable direct hemolysin (TDH) and TDH-related hemolysin of Vibrio parahaemolyticus with gastroenteritis. Infect Immun (1990) 3.17
Characterization of a plasmid-borne and constitutively expressed blaMOX-1 gene encoding AmpC-type beta-lactamase. Gene (1994) 3.08
IL-6 is required for the development of Th1 cell-mediated murine colitis. J Immunol (2000) 3.08
Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J Biol Chem (2000) 2.99
Chronic bone marrow failure due to persistent B19 parvovirus infection. N Engl J Med (1987) 2.93
Studies on the mass receptor potential of the isolated frog retina. II. On the basis of the ionic mechanism. Vision Res (1969) 2.91
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem (1996) 2.77
Replication of the B19 parvovirus in human bone marrow cell cultures. Science (1986) 2.75
Novel transcription map for the B19 (human) pathogenic parvovirus. J Virol (1987) 2.74
Postexposure prophylaxis of varicella in family contact by oral acyclovir. Pediatrics (1993) 2.67
Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli. J Biol Chem (1983) 2.66
Polymicrogyria is an uncommon manifestation in 22q11.2 deletion syndrome. Am J Med Genet (2000) 2.54
Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Mol Cell Biol (1992) 2.53
SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol Cell (1999) 2.52
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures. J Cell Biol (2001) 2.51
Mechanism of action of quinolones against Escherichia coli DNA gyrase. Antimicrob Agents Chemother (1993) 2.48
Genomic organization of the Klebsiella pneumoniae cps region responsible for serotype K2 capsular polysaccharide synthesis in the virulent strain Chedid. J Bacteriol (1995) 2.47
Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J Biol Chem (1996) 2.43
STAT3 is required for the gp130-mediated full activation of the c-myc gene. J Exp Med (1999) 2.36
Chlorophyll a oxygenase (CAO) is involved in chlorophyll b formation from chlorophyll a. Proc Natl Acad Sci U S A (1998) 2.35
Downregulation of beta1 integrins by Ebola virus glycoprotein: implication for virus entry. Virology (2000) 2.33
Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res (1994) 2.29
A large family of class III plant peroxidases. Plant Cell Physiol (2001) 2.21
Simultaneous occurrence of human herpesvirus 6 infection and intussusception in three infants. Pediatr Infect Dis J (1991) 2.16
Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nat Med (2000) 2.16
Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload. J Clin Invest (1995) 2.15
Late thoracic outlet syndrome secondary to malunion of the fractured clavicle: case report and review of the literature. J Trauma (2001) 2.14
A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin. J Biol Chem (1990) 2.12
EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase. EMBO J (1996) 2.11
Frequent amplification of the c-met gene in scirrhous type stomach cancer. Biochem Biophys Res Commun (1992) 2.11
Sequence conservation of the catalytic regions of amylolytic enzymes in maize branching enzyme-I. Biochem Biophys Res Commun (1991) 2.07
Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome. J Virol (1997) 2.06
Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors. Mol Cell Biol (2001) 2.03
Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine. J Biochem (1996) 2.00
Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12. Nucleic Acids Res (1994) 2.00
Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression. Nat Cell Biol (2000) 1.99
A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle. Mol Cell Biol (1992) 1.97
Studies on the mass receptor potential of the isolated frog retina. I. General properties of the response. Vision Res (1969) 1.97
Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse. Nat Neurosci (2001) 1.96
Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis. Nat Med (1999) 1.95
Protein-protein interaction of zinc finger LIM domains with protein kinase C. J Biol Chem (1996) 1.90
Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase. J Biol Chem (1996) 1.90
Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation. Mol Biol Cell (2001) 1.88
Nosocomial spread of cephem-resistant Escherichia coli strains carrying multiple Toho-1-like beta-lactamase genes. Antimicrob Agents Chemother (1997) 1.84
Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs. J Biol Chem (1995) 1.84
Evaluation of the therapeutic effect of radiotherapy on cervical cancer using magnetic resonance imaging. Int J Radiat Oncol Biol Phys (1999) 1.82
Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. Nat Med (1999) 1.82
Characterization of capsid and noncapsid proteins of B19 parvovirus propagated in human erythroid bone marrow cell cultures. J Virol (1987) 1.77
A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons. Neuron (2000) 1.76
A cDNA clone closely associated with non-A, non-B hepatitis. Nucleic Acids Res (1990) 1.76
A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells. J Biol Chem (1994) 1.75
Results of surgical treatment for intrahepatic cholangiocarcinoma and clinicopathological factors influencing survival. Br J Surg (2002) 1.75
Productive infection by B19 parvovirus of human erythroid bone marrow cells in vitro. Blood (1987) 1.75
Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells. Osteoarthritis Cartilage (2006) 1.74
ORP150 protects against hypoxia/ischemia-induced neuronal death. Nat Med (2001) 1.74
Arachidonic acid metabolites as intracellular modulators of the G protein-gated cardiac K+ channel. Nature (1989) 1.74
Characterization of pyridoxine auxotrophs of Escherichia coli: serine and pdxF mutants. J Bacteriol (1970) 1.72
Messenger RNA targeting of rice seed storage proteins to specific ER subdomains. Nature (2000) 1.72
Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice. EMBO J (2000) 1.70
Susceptibility of hepatitis B virus to disinfectants or heat. J Clin Microbiol (1984) 1.70
A role for reactive oxygen species in endothelial cell anoikis. Circ Res (1999) 1.69
Expression of epidermal growth factor receptor in human gastric and colonic carcinomas. Cancer Res (1988) 1.67
Immunohistologic study of the ruptured intervertebral disc of the lumbar spine. Spine (Phila Pa 1976) (1996) 1.66
Promotion of the uptake of PS liposomes and apoptotic cells by a product of growth arrest-specific gene, gas6. J Biochem (2000) 1.64
CIRCULATING IMMUNITY PRINCIPLES IN RAT-BITE FEVER. J Exp Med (1917) 1.64
Influenza A virus can undergo multiple cycles of replication without M2 ion channel activity. J Virol (2001) 1.63
Radioisotopic studies on renewal of opsin. Vision Res (1968) 1.63
Resection of hepatic and pulmonary metastases in patients with colorectal carcinoma. Cancer (1998) 1.62
PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation. Nat Neurosci (2001) 1.62
Vascular endothelial growth factor secreted by replicating hepatocytes induces sinusoidal endothelial cell proliferation during regeneration after partial hepatectomy in rats. J Hepatol (2001) 1.62
Identification of species and capsular types of Klebsiella clinical isolates, with special reference to Klebsiella planticola. Microbiol Immunol (1989) 1.60
A controlled trial of combined therapy for newly diagnosed severe childhood IgA nephropathy. The Japanese Pediatric IgA Nephropathy Treatment Study Group. J Am Soc Nephrol (1999) 1.60
Voluntarily evoked positive Lachman test produced by gastrocnemius muscle contraction. A report of three cases. Am J Sports Med (2001) 1.60
Systematic review and meta-analysis: importance of CagA status for successful eradication of Helicobacter pylori infection. Aliment Pharmacol Ther (2006) 1.60
Serum granulocyte colony-stimulating factor levels in healthy volunteers and patients with various disorders as estimated by enzyme immunoassay. Blood (1989) 1.60
Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene. J Clin Invest (1994) 1.60
Effective hepatic artery chemoembolization for advanced hepatocellular carcinoma with extensive tumour thrombus through the hepatic vein. J Gastroenterol Hepatol (1999) 1.59