Published in Biochemistry on January 01, 1966
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Polymer synthesis in killed bacteria: lethality of 2',3'-dideoxyadenosine. J Bacteriol (1966) 1.26
The enzymatic termination of polydeoxynucleotides by 2',3'-dideoxyadenosine triphosphate. Proc Natl Acad Sci U S A (1969) 1.09
Termination of deoxyribonucleic acid in Escherichia coli by 2',3'-dideoxyadenosine. J Bacteriol (1970) 1.05
Purine nucleosides. XIV. Unsaturated furanosyl adenine nucleosides prepared via base-catalyzed elimination reactions of 2'-deoxyadenosine derivatives. J Am Chem Soc (1966) 57.26
Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide. Science (1972) 7.74
Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent. Proc Natl Acad Sci U S A (1973) 4.36
Design, synthesis, and broad spectrum antiviral activity of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides. J Med Chem (1972) 4.12
In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses. Antimicrob Agents Chemother (1973) 4.04
N-6-(delta-3-isopentenyl) adenosine. A component of the transfer ribonucleic acid of yeast and of mammalian tissue, methods of isolation, and characterization. Biochemistry (1967) 2.37
In vitro and in vivo comparison of the abilities of purine and pyrimidine 2',3'-dideoxynucleosides to inhibit duck hepadnavirus. Antimicrob Agents Chemother (1989) 1.90
Suppression by 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) of influenza virus-induced infections in mice. Antimicrob Agents Chemother (1973) 1.87
The relationship between the metabolism of ribavirin and its proposed mechanism of action. Ann N Y Acad Sci (1977) 1.79
Chemical synthesis and biological activity of 8-substituted adenosine 3',5'-cyclic monophosphate derivatives. Biochemistry (1971) 1.63
Purine nucleosides. XI. The synthesis of 2'-deoxy-9-alpha- and-beta-D-ribofuranosylpurines and the correlation of their anomeric structure with proton magnetic resonance spectra. J Am Chem Soc (1965) 1.63
Synthesis and antitumor activity of 2-beta-D-ribofuranosylselenazole-4- carboxamide and related derivatives. J Med Chem (1983) 1.57
Effect of 1-beta-D-ribofuranosyl1-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on herpes and vaccinia keratitis and encephalitis in laboratory animals. Antimicrob Agents Chemother (1973) 1.42
Growth inhibition and induction of cellular differentiation of human myeloid leukemia cells in culture by carbamoyl congeners of ribavirin. J Med Chem (1990) 1.37
Inhibition of duck hepatitis B virus replication by purine 2',3'-dideoxynucleosides. Biochem Biophys Res Commun (1988) 1.34
Carbon-13 magnetic resonance. XVII. Pyrimidine and purine nucleosides. J Am Chem Soc (1970) 1.34
Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent. Antimicrob Agents Chemother (1983) 1.33
Nucleic acid related compounds. 12. The facile and high-yield stannous chloride catalyzed monomethylation of the cis-glycol system of nucleosides by diazomethane. J Org Chem (1974) 1.31
Nucleic acid related compounds. 1. Methylation and transformation of 4-methoxy-2-pyrimidinone 1- -D-ribofuranoside into 2'-O-methyl nucleoside components of ribonucleic acid, their analogs, and derivatives. Biochemistry (1971) 1.27
Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo. Proc Natl Acad Sci U S A (1980) 1.26
Effect of selenazofurin on influenza A and B virus infections of mice. Antiviral Res (1986) 1.25
Biochemical differences among four inosinate dehydrogenase inhibitors, mycophenolic acid, ribavirin, tiazofurin, and selenazofurin, studied in mouse lymphoma cell culture. Cancer Res (1985) 1.22
Synthesis and biochemical studies of various 8-substituted derivatives of guanosine 3',5'-cyclic phosphate, inosine 3',5'-cyclic phosphate, and xanthosine 3',5'-cyclic phosphate. Biochemistry (1973) 1.18
2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase. J Med Chem (1991) 1.18
Optical rotatory dispersion, circular dichroism, and absorption studies on some naturally occurring ribonucleosides and related derivatives. Proc Natl Acad Sci U S A (1967) 1.17
Cutaneous closure after cardiac operations: a controlled, randomized, prospective comparison of intradermal versus staple closures. Ann Surg (1997) 1.17
Ribavirin: an antiviral agent. Pharmacol Ther (1979) 1.16
Inhibition of RNA virus replication in vitro by 3-deazacytidine and 3-deazauridine. Proc Soc Exp Biol Med (1972) 1.16
Photoaffinity labeling of the human erythrocyte nucleoside transporter by N6-(p-Azidobenzyl)adenosine and nitrobenzylthioinosine. Evidence that the transporter is a band 4.5 polypeptide. J Biol Chem (1983) 1.15
Nuclear magnetic resonance determination of syn and anti conformations in pyrimidine nucleosides. J Am Chem Soc (1971) 1.14
The chemistry and biological properties of nucleotides related to nucleoside 3',5'-cyclic phosphates. Adv Cyclic Nucleotide Res (1973) 1.13
2' Derivatives of guanosine and inosine cyclic 3',5'-phosphates. Synthesis, enzymic activity, and the effect of 8-substituents. Biochemistry (1976) 1.13
Purine nucleosides. XV. The synthesis of 8-aminoand 8-substituted aminopurine nucleosides. J Org Chem (1967) 1.11
Activity of purine analogs against Leishmania tropica within human macrophages in vitro. Antimicrob Agents Chemother (1983) 1.09
Carbon-13 nuclear magnetic resonance: naturally occurring nucleosides. Proc Natl Acad Sci U S A (1970) 1.08
Sugar-modified N 6 -(3-methyl-2-butenyl)adenosine derivatives, N 6 -benzyl analogs, and cytokinin-related nucleosides containing sulfur or formycin. Biochemistry (1973) 1.08
Purine nucleosides. XVI. Synthesis of the naturally occurring 2 -O-methylpurine ribonucleosides and related derivatives. J Am Chem Soc (1966) 1.07
Purine nucleosides. 8. The synthesis of 2-fluoro- and 2-chloroinosine and certain derived purine nucleosides. J Org Chem (1966) 1.05
Detection of a new substrate-derived radical during inactivation of ribonucleotide reductase from Escherichia coli by gemcitabine 5'-diphosphate. Biochemistry (1998) 1.05
Nucleic acid related compounds. II. A rapid and quantitative preparation of 2'-0- and 3'-0-methyl nucleosides. Biochim Biophys Acta (1971) 1.04
Circular dichroism of nucleoside derivatives. IV. Uracil derivatives. J Am Chem Soc (1969) 1.04
Design and synthesis of a series of non-peptide high-affinity human corticotropin-releasing factor1 receptor antagonists. J Med Chem (1996) 1.03
The role of the 5'-hydroxyl group of adenosine in determining substrate specificity for adenosine deaminase. J Med Chem (1967) 1.02
Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity. Antimicrob Agents Chemother (1987) 1.02
Circular dichroism of nucleoside derivatives. IX. Vicinal effects on the circular dichroism of pyrimidine nucleosides. J Am Chem Soc (1970) 1.01
Synthesis and antiviral/antitumor activities of certain 3-deazaguanine nucleosides and nucleotides. J Med Chem (1984) 1.01
Efficacy of 9-beta-D-arabinofuranosylhypoxanthine 5'-monophosphate in therapy of equine abortion virus-induced hepatitis in hamsters. Antimicrob Agents Chemother (1975) 1.01
Pyrrolopyrimidine nucleosides. 3. The total synthesis of toyocamycin, sangivamycin, tubercidin, and related derivatives. J Am Chem Soc (1969) 1.01
Synthesis and antimicrobial activity of some novel heterocycles. Azolo-as-triazines. J Med Chem (1976) 1.01
The 2',3'-dideoxyriboside of 2,6-diaminopurine selectively inhibits human immunodeficiency virus (HIV) replication in vitro. Biochem Biophys Res Commun (1987) 1.00
Circular dichroism of nucleoside derivatives. V. Cytosine derivatives. J Am Chem Soc (1969) 1.00
Antiviral activity of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid. Antimicrob Agents Chemother (1977) 1.00
Aerosol and intraperitoneal administration of ribavirin and ribavirin triacetate: pharmacokinetics and protection of mice against intracerebral infection with influenza A/WSN virus. Antimicrob Agents Chemother (1991) 1.00
Nucleic acid related compounds. 11. Adenosine 2',3'-ribo-epoxide. Synthesis, intramolecular degradation, and transformation into 3'-substituted xylofuranosyl nucleosides and the lyxo-epoxide. J Org Chem (1974) 1.00
Synthesis and antischistosomal activity of certain pyrazolo[1,5-a]pyrimidines. J Med Chem (1981) 0.99
Antiviral mechanisms of action. Annu Rev Pharmacol Toxicol (1980) 0.99
Synthesis and antiviral activity of certain 5'-monophosphates of 9-D-arabinofuranosyladenine and 9-D-arabinofuranosylhypoxanthine. J Med Chem (1975) 0.99
The phosphorylation of ribavirin by deoxyadenosine kinase from rat liver. Differentiation between adenosine and deoxyadenosine kinase. Biochemistry (1974) 0.99
Mild and efficient functionalization at C6 of purine 2'-deoxynucleosides and ribonucleosides. Org Lett (2000) 0.98
Effect of 9-beta-D-arabinofuranosylhypoxanthine 5'-monophosphate on genital lesions and encephalitis induced by Herpesvirus hominis type 2 in female mice. J Infect Dis (1976) 0.98
Synthesis and antiviral activity of 1,2,4-triazole-3-thiocarboxamide and 1,2,4-triazole-3-carboxamidine ribonucleosides. J Med Chem (1973) 0.98
Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193). Biochem Pharmacol (1982) 0.98
Synergistic antiviral effects of ribavirin and the C-nucleoside analogs tiazofurin and selenazofurin against togaviruses, bunyaviruses, and arenaviruses. Antimicrob Agents Chemother (1984) 0.98
Synthesis and cardiotonic activity of novel biimidazoles. J Med Chem (1990) 0.97
Pyrimidine nucleosides. I. The synthesis of 6-methylcytidine, 6-methyluridine, and related 6-methylpyrimidine nucleosides. J Org Chem (1968) 0.97
Broad-spectrum in vivo antiviral activity of 7-thia-8-oxoguanosine, a novel immunopotentiating agent. Antimicrob Agents Chemother (1989) 0.97
Thiazolo[4,5-d]pyrimidine nucleosides. The synthesis of certain 3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidines as potential immunotherapeutic agents. J Med Chem (1990) 0.96
Vicinal effects on the optical activity of some adenine nucleosides. J Phys Chem (1968) 0.96
Alkylpurines as immunopotentiating agents. Synthesis and antiviral activity of certain alkylguanines. J Med Chem (1993) 0.96
Synthesis and antifungal properties of certain 7-alkylaminopyrazolo[1,5-a]pyrimidines. J Med Chem (1977) 0.96
2-beta-D-Ribofuranosylthiazole-4-carboxamide, a novel potential antitumor agent for lung tumors and metastases. J Med Chem (1982) 0.94
Synthesis of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid by a novel ring closure of imidazole precursors. J Am Chem Soc (1976) 0.94
Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth. FEBS Lett (1987) 0.94
Anti-DNA virus activity of the 5'-nucleotide and 3',5'-cyclic nucleotide of 9-beta-D-arabinofuranosyladenine. Chemotherapy (1973) 0.93
Synthesis and antiviral and enzymatic studies of certain 3-deazaguanines and their imidazolecarboxamide precursors. J Med Chem (1978) 0.92
Synthesis and biological activity of some 2' derivatives of adenosine 3',5'-cyclic phosphate. Biochemistry (1973) 0.92
Synthesis and biological activity of selected 2,6-disubstituted-(2-deoxy- -and- -D-erythro-pentofuranosyl)purines. J Med Chem (1972) 0.92
Gemcitabine 5'-triphosphate is a stoichiometric mechanism-based inhibitor of Lactobacillus leichmannii ribonucleoside triphosphate reductase: evidence for thiyl radical-mediated nucleotide radical formation. Biochemistry (1998) 0.92
Calf intestine adenosine deaminase. Substrate specificity. Biochemistry (1970) 0.92
Site-selective cyclic AMP analogs as new biological tools in growth control, differentiation, and proto-oncogene regulation. Cancer Invest (1989) 0.91
Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate. Biochemistry (1993) 0.91
Azapurine nucleosides. 2. Synthesis and antiviral activity of 7-amino-3- -D-arabinofuranosyl-v-triazolo (4,5-d)pyrimidine and related nucleosides. J Med Chem (1972) 0.91
Nucleic acid related compounds. 20. Sugar, base doubly modified nucleosides at the 5'-terminal "cap" of mRNAs and in nuclear RNA. Biochem Biophys Res Commun (1976) 0.91
Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitors. Biochemistry (1996) 0.90
Synthesis and antiviral activity of certain thiazole C-nucleosides. J Med Chem (1977) 0.90
Inhibition of inosinate dehydrogenase by metabolites of 2-beta-D-ribofuranosyl thiazole-4-carboxamide. Biochem Biophys Res Commun (1982) 0.90
Circular dichroism of nucleoside derivatives. VI. The optically active bands of adenine nucleoside derivatives. Proc Natl Acad Sci U S A (1969) 0.90
Purine nucleosides. XXIX. The synthesis of 2'-deoxy-L-adenosine and 2'-deoxy-L-guanosine and their alpha anomers. J Org Chem (1970) 0.90