Clinicopathologic conference.

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89

Bacillus thuringiensis and its pesticidal crystal proteins. Microbiol Mol Biol Rev (1998) 13.47

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature (2000) 6.54

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell (1990) 6.17

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature (2000) 5.86

Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol (1998) 5.69

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci U S A (1997) 4.89

A systematic, high-resolution linkage of the cytogenetic and physical maps of the human genome. Nat Genet (2000) 4.78

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell (1989) 4.73

Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science (1990) 4.19

Revision of the nomenclature for the Bacillus thuringiensis pesticidal crystal proteins. Microbiol Mol Biol Rev (1998) 4.14

Chemotaxis of polymorphonuclear leukocytes from patients with rheumatoid arthritis. J Clin Invest (1971) 3.61

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc Natl Acad Sci U S A (1993) 3.56

Current proposed revision of JRA Criteria. JRA Criteria Subcommittee of the Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Section of The Arthritis Foundation. Arthritis Rheum (1977) 3.51

Chemotaxis of polymorphonuclear leukocytes from patients with diabetes mellitus. N Engl J Med (1971) 2.98

Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes. Cell (1993) 2.93

Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes (1996) 2.83

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol Psychiatry (1995) 2.72

Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein. Proc Natl Acad Sci U S A (1994) 2.70

Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol (2001) 2.69

Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell (1994) 2.68

Chimeric prion protein expression in cultured cells and transgenic mice. Protein Sci (1992) 2.67

Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature (1995) 2.61

A study of classification criteria for a diagnosis of juvenile rheumatoid arthritis. Arthritis Rheum (1986) 2.56

MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: a feasibility study. Radiology (2001) 2.54

Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell (2001) 2.45

Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc Natl Acad Sci U S A (1994) 2.37

Intra-alveolar haemorrhage in sudden infant death syndrome: a cause for concern? J Clin Pathol (1999) 2.37

Gene organization and regulation in the qa (quinic acid) gene cluster of Neurospora crassa. Microbiol Rev (1985) 2.33

Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature (2000) 2.16

Natural history and surgical dilemma of "stress" gastric bleeding. Arch Surg (1971) 2.13

L-myo-inositol 1,4,5,6-tetrakisphosphate is present in both mammalian and avian cells. Biochem J (1988) 2.10

Micrococcus luteus -- survival in amber. Microb Ecol (2004) 2.02

Immunofluorescent demonstration of an IgG-B1C complex in synovial lining cells of rheumatoid synovial membrane. Clin Exp Immunol (1969) 2.00

Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. J Neurosci (1998) 1.99

Effect of smoking history on [3H]nicotine binding in human postmortem brain. J Pharmacol Exp Ther (1997) 1.98

Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein. Proc Natl Acad Sci U S A (1999) 1.93

Schizophrenia, sensory gating, and nicotinic receptors. Schizophr Bull (1998) 1.92

Prevalence of restless legs syndrome among men aged 18 to 64 years: an association with somatic disease and neuropsychiatric symptoms. Mov Disord (2001) 1.89

Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis. Development (1996) 1.88

Mitomycin C treatment for conjunctival-corneal intraepithelial neoplasia: a multicenter experience. Ophthalmology (1997) 1.85

Signal transduction through lipid second messengers. Curr Opin Cell Biol (1996) 1.84

Are coroners' necropsies necessary? A prospective study examining whether a "view and grant" system of death certification could be introduced into England and Wales. J Clin Pathol (2001) 1.82

A simplified method for the measurement of chemotaxis of polymorphonuclear leukocytes from human blood. J Lab Clin Med (1971) 1.81

Production of a severe cystic fibrosis mutation in mice by gene targeting. Nat Genet (1993) 1.80

Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia. Neuropsychopharmacology (2000) 1.77

Benefits and disadvantages of joint hypermobility among musicians. N Engl J Med (1993) 1.74

Basic tear flow. Does it exist? Ophthalmology (1980) 1.74

Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10. Proc Natl Acad Sci U S A (1991) 1.74

Comparison of the regional expression of nicotinic acetylcholine receptor alpha7 mRNA and [125I]-alpha-bungarotoxin binding in human postmortem brain. J Comp Neurol (1997) 1.72

Isolation of the gene for McLeod syndrome that encodes a novel membrane transport protein. Cell (1994) 1.65

Pyruvate kinase type M2: a crossroad in the tumor metabolome. Br J Nutr (2002) 1.65

Hereditary deficiency of the sixth component of complement in man. I. Immunochemical, biologic, and family studies. J Clin Invest (1974) 1.65

Effect on patient management of a weekend 'on-call' nuclear medicine service. Nucl Med Commun (1994) 1.61

Dysregulated expression of neutrophil apoptosis in the systemic inflammatory response syndrome. Arch Surg (1997) 1.60

Hypermobility: features and differential incidence between the sexes. Arthritis Rheum (1987) 1.59

Haemophilus influenzae meningitis in an adult. A study of bactericidal antibodies and immunoglobulins. N Engl J Med (1970) 1.58

Clinically atypical granular corneal dystrophy with pathologic features of lattice-like amyloid deposits. A study of these families. Ophthalmology (1988) 1.55

Immunologic responses to Hemophilus influenzae meningitis. J Pediatr (1972) 1.53

Extended-wear contact lenses and pseudomonal corneal ulcers. Am J Ophthalmol (1986) 1.53

Evidence against the involvement of chemotaxis in swarming of Proteus mirabilis. J Bacteriol (1976) 1.53

Amino acid sequence of human histidine-rich glycoprotein derived from the nucleotide sequence of its cDNA. Biochemistry (1986) 1.52

Structure and dynamics of the acid-denatured molten globule state of alpha-lactalbumin: a two-dimensional NMR study. Biochemistry (1993) 1.52

Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice. Neuron (1991) 1.51

The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells. J Exp Med (2000) 1.50

Role of snoring and daytime sleepiness in occupational accidents. Am J Respir Crit Care Med (2001) 1.50

Studies of isolated synovial living cells of rheumatoid and nonrheumatoid synovial membranes. Arthritis Rheum (1971) 1.49

Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer. Br J Cancer (2004) 1.48

Coupled chemical and mechanical reaction steps in a processive Neurospora kinesin. EMBO J (1999) 1.48

Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7). Am J Med Genet (2001) 1.47

Characterization of a cDNA coding for human protein C. Proc Natl Acad Sci U S A (1984) 1.45

Two-dimensional and Doppler echocardiography alone can adequately define preoperative anatomy and hemodynamic status before repair of complete atrioventricular septal defect in infants < 1 year old. J Am Coll Cardiol (1994) 1.44

Infection in rheumatoid arthritis. Arthritis Rheum (1971) 1.44

Decreased 19S antibody response to bacterial antigens in systemic lupus erythematosus. J Clin Invest (1969) 1.43

Alpha-bungarotoxin binding to hippocampal interneurons: immunocytochemical characterization and effects on growth factor expression. J Neurosci (1993) 1.42

Recombination in a schizophrenic proband fails to exclude CHRNA7 at chromosome 15q14. Mol Psychiatry (2003) 1.41

Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology (1996) 1.41

Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis. J Clin Invest (2001) 1.40

Unfairness for mouth cancer patients. Br Dent J (2012) 1.39

[A simple bite protector for the laryngeal mask]. Anasthesiol Intensivmed Notfallmed Schmerzther (1994) 1.39

Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis. J Biol Chem (1990) 1.36

Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7. Oncogene (2001) 1.36

Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7). Genomics (1998) 1.36

Membrane phospholipid abnormalities in postmortem brains from schizophrenic patients. Schizophr Res (2000) 1.34

Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin. Cancer Res (1996) 1.33

Describing the phenotype in Rett syndrome using a population database. Arch Dis Child (2003) 1.33

The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy. J Bioenerg Biomembr (1997) 1.32

Schistosoma mansoni in IL-4-deficient mice. Int Immunol (1996) 1.32

Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity? Br J Cancer (2007) 1.32

Brain pH has a significant impact on human postmortem hippocampal gene expression profiles. Brain Res (2006) 1.31

Alternative phenotypes for the complex genetics of schizophrenia. Biol Psychiatry (1999) 1.31

Polymorphonuclear leucocyte chemotaxis in patients with bacterial infections. Br Med J (1971) 1.30

Freshly fractured quartz inhalation leads to enhanced lung injury and inflammation. Potential role of free radicals. Am J Respir Crit Care Med (1995) 1.29

Sports injuries at the 1985 Junior Olympics. An epidemiologic analysis. Am J Sports Med (1988) 1.29

Chromosome specific paints from a high resolution flow karyotype of the mouse. Nat Genet (1995) 1.28

Alcohol consumption raises HDL cholesterol levels by increasing the transport rate of apolipoproteins A-I and A-II. Circulation (2000) 1.25

Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections? Immunobiology (2010) 1.25

Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos? Toxicol Appl Pharmacol (2011) 1.25

The hypermobility syndrome. Pediatrics (1983) 1.24