Published in Int Immunol on April 01, 1996
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J Clin Invest (1999) 4.22
Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J Exp Med (1999) 3.40
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response. J Exp Med (2003) 2.71
Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths. Nat Rev Immunol (2013) 1.96
Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses. Immunity (2015) 1.75
Schistosomiasis decreases central nervous system inflammation and alters the progression of experimental autoimmune encephalomyelitis. Infect Immun (2003) 1.45
Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans. J Exp Med (1998) 1.37
Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection. Proc Natl Acad Sci U S A (2001) 1.16
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis. Proc Natl Acad Sci U S A (2013) 1.16
Signaling via interleukin-4 receptor alpha chain is required for successful vaccination against schistosomiasis in BALB/c mice. Infect Immun (2001) 1.02
Differential liver protein expression during schistosomiasis. Infect Immun (2006) 0.95
Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative activation of macrophages. J Biol Chem (2013) 0.95
Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis. Infect Immun (2003) 0.94
Absence of interleukin-4 determines less severe pulmonary paracoccidioidomycosis associated with impaired Th2 response. Infect Immun (2004) 0.89
The common gamma chain cytokines interleukin (IL)-2 and IL-7 indirectly modulate blood fluke development via effects on CD4+ T cells. J Infect Dis (2006) 0.89
IL-13 Signaling in Liver Fibrogenesis. Front Immunol (2012) 0.88
Interleukin-13 fusion cytotoxin arrests Schistosoma mansoni egg-induced pulmonary granuloma formation in mice. Am J Pathol (2002) 0.86
Interleukin-4 (IL-4) and IL-13 signaling pathways do not regulate Borrelia burgdorferi-induced arthritis in mice: IgG1 is not required for host control of tissue spirochetes. Infect Immun (2000) 0.85
Polarization of the immune response to the single immunodominant epitope of p38, a major Schistosoma mansoni egg antigen, generates Th1- or Th2-type cytokines and granulomas. Infect Immun (1999) 0.84
Severe schistosomiasis in the absence of interleukin-4 (IL-4) is IL-12 independent. Infect Immun (2001) 0.83
Beneficial autoimmunity at body surfaces - immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer. Front Immunol (2014) 0.79
The Metabolic Prospective and Redox Regulation of Macrophage Polarization. J Clin Cell Immunol (2015) 0.78
Role of gamma interferon in the pathogenesis of severe schistosomiasis in interleukin-4-deficient mice. Infect Immun (2001) 0.78
Schistosomiasis-associated pulmonary hypertension. Pulm Circ (2014) 0.76
Interleukin-12 modulates T-cell responses to microfilariae but fails to abrogate interleukin-5-dependent immunity in a mouse model of onchocerciasis. Immunology (1999) 0.75
Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89
Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature (1988) 5.56
Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci U S A (1997) 4.89
Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J Immunol (1992) 4.02
Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism. Infect Immun (1998) 3.80
Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J Immunol (1991) 3.65
Resistance of mice deficient in IL-4 to retrovirus-induced immunodeficiency syndrome (MAIDS) Science (1993) 3.51
Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous. J Immunol (1999) 2.77
Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol Psychiatry (1995) 2.72
The importance of Th2 cytokines in protective immunity to nematodes. Immunol Rev (1992) 2.69
The role of interleukin-6 in mucosal IgA antibody responses in vivo. Science (1994) 2.53
IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. Eur J Immunol (1998) 2.44
Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia. J Infect Dis (1997) 2.39
Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome. Chest (1995) 2.38
Interleukin 6 plays a key role in the development of antigen-induced arthritis. Proc Natl Acad Sci U S A (1998) 2.37
Lethal tuberculosis in interleukin-6-deficient mutant mice. Infect Immun (1997) 2.31
Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Curr Biol (1998) 2.24
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature (2000) 2.16
Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection. Eur J Immunol (1999) 2.11
Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice. J Clin Invest (1998) 2.06
Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. J Neurosci (1998) 1.99
Effect of smoking history on [3H]nicotine binding in human postmortem brain. J Pharmacol Exp Ther (1997) 1.98
Mouse Eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response. Immunity (1996) 1.96
Schizophrenia, sensory gating, and nicotinic receptors. Schizophr Bull (1998) 1.92
Interleukin-4 is required for the induction of lung Th2 mucosal immunity. Am J Respir Cell Mol Biol (1995) 1.92
B cell-stimulatory factor 1 (BSF-1) promotes growth of helper T cell lines. J Exp Med (1986) 1.82
Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia. Neuropsychopharmacology (2000) 1.77
Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice. J Immunol (1997) 1.76
Comparison of the regional expression of nicotinic acetylcholine receptor alpha7 mRNA and [125I]-alpha-bungarotoxin binding in human postmortem brain. J Comp Neurol (1997) 1.72
Impaired mucosal immune responses in interleukin 4-targeted mice. J Exp Med (1995) 1.71
The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice. Eur J Immunol (1994) 1.63
Allergic airway inflammation is exacerbated during acute influenza infection and correlates with increased allergen presentation and recruitment of allergen-specific T-helper type 2 cells. Clin Exp Allergy (2004) 1.60
A high-throughput alphavirus-based expression cloning system for mammalian cells. Nat Biotechnol (2001) 1.55
Evidence against the involvement of chemotaxis in swarming of Proteus mirabilis. J Bacteriol (1976) 1.53
Granzyme A-deficient mice retain potent cell-mediated cytotoxicity. EMBO J (1995) 1.52
Interleukin 4 mediates autocrine growth of helper T cells after antigenic stimulation. Proc Natl Acad Sci U S A (1986) 1.51
Interleukin 6 is essential for in vivo development of B lineage neoplasms. J Exp Med (1995) 1.49
Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7). Am J Med Genet (2001) 1.47
Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness. J Exp Med (1997) 1.44
Two-dimensional and Doppler echocardiography alone can adequately define preoperative anatomy and hemodynamic status before repair of complete atrioventricular septal defect in infants < 1 year old. J Am Coll Cardiol (1994) 1.44
CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivo. J Exp Med (1999) 1.44
Epitopes on CD45R [T200] molecules define differentiation antigens on murine B and T lymphocytes. J Mol Cell Immunol (1988) 1.43
Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells. J Exp Med (1999) 1.42
Alpha-bungarotoxin binding to hippocampal interneurons: immunocytochemical characterization and effects on growth factor expression. J Neurosci (1993) 1.42
Recombination in a schizophrenic proband fails to exclude CHRNA7 at chromosome 15q14. Mol Psychiatry (2003) 1.41
Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology (1996) 1.41
Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response. J Immunol (1995) 1.40
Endogenous interleukin 4 is required for development of protective CD4+ T helper type 1 cell responses to Candida albicans. J Exp Med (1998) 1.37
Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis. J Biol Chem (1990) 1.36
Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7). Genomics (1998) 1.36
Interleukin-6 is required in vivo for the regulation of stem cells and committed progenitors of the hematopoietic system. Immunity (1994) 1.34
Membrane phospholipid abnormalities in postmortem brains from schizophrenic patients. Schizophr Res (2000) 1.34
Describing the phenotype in Rett syndrome using a population database. Arch Dis Child (2003) 1.33
Alternative phenotypes for the complex genetics of schizophrenia. Biol Psychiatry (1999) 1.31
Brain pH has a significant impact on human postmortem hippocampal gene expression profiles. Brain Res (2006) 1.31
Dual role of the IL-12/IFN-gamma axis in the development of autoimmune myocarditis: induction by IL-12 and protection by IFN-gamma. J Immunol (2001) 1.31
IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-gamma and nitric oxide synthetase 2. J Immunol (2000) 1.30
Comparison of three methods for the detection of Trichinella spiralis infections in pigs by five European laboratories. Bull World Health Organ (1974) 1.30
Freshly fractured quartz inhalation leads to enhanced lung injury and inflammation. Potential role of free radicals. Am J Respir Crit Care Med (1995) 1.29
Antifungal type 1 responses are upregulated in IL-10-deficient mice. Microbes Infect (1999) 1.27
CD2 sets quantitative thresholds in T cell activation. J Exp Med (1999) 1.27
Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos? Toxicol Appl Pharmacol (2011) 1.25
Schizophrenia and nicotinic receptors. Harv Rev Psychiatry (1998) 1.22
Normal pathogen-specific immune responses mounted by CTLA-4-deficient T cells: a paradigm reconsidered. Eur J Immunol (2001) 1.21
Abundance, diversity, and patterns of distribution of primates on the Tapiche River in Amazonian Peru. Am J Primatol (2001) 1.21
Influenza virus: a novel method to assess viral and neutralizing antibody titers in vitro. J Immunol Methods (1999) 1.20
Sensory impairments and delayed regeneration of sensory axons in interleukin-6-deficient mice. J Neurosci (1999) 1.19
Interleukin-4 causes susceptibility to invasive pulmonary aspergillosis through suppression of protective type I responses. J Infect Dis (1999) 1.19
The antigen dose determines T helper subset development by regulation of CD40 ligand. Eur J Immunol (2000) 1.19
CpG oligodeoxynucleotides and interleukin-12 improve the efficacy of Mycobacterium bovis BCG vaccination in mice challenged with M. tuberculosis. Infect Immun (2000) 1.19
Evidence for the multigenic inheritance of schizophrenia. Am J Med Genet (2001) 1.18
Interleukin 4 and T helper type 2 cells are required for development of experimental onchocercal keratitis (river blindness). J Exp Med (1995) 1.18
Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers. Brain Res Mol Brain Res (2005) 1.17
NURR1 mutations in cases of schizophrenia and manic-depressive disorder. Am J Med Genet (2000) 1.16
The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. J Chem Neuroanat (2000) 1.14
IFN-gamma is required for IL-12 responsiveness in mice with Candida albicans infection. J Immunol (1998) 1.12
Hapten-induced colitis associated with maintained Th1 and inflammatory responses in IFN-gamma receptor-deficient mice. Eur J Immunol (2000) 1.12
Cytokines and infectious diseases. Immunol Today (1997) 1.10
Comparison of three methods for detection of prolonged experimental trichinellosis in pigs. Vet Parasitol (1984) 1.09
The accuracy of parental reports of their children's intake of fruits and vegetables: validation of a food frequency questionnaire with serum levels of carotenoids and vitamins C, A, and E. Epidemiology (1993) 1.09
Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biol Psychiatry (1993) 1.08
Personal best marathon performance is associated with performance in a 24-h run and not anthropometry or training volume. Br J Sports Med (2008) 1.06
IL-6-deficient mice exhibit normal mucosal IgA responses to local immunizations and Helicobacter felis infection. J Immunol (1996) 1.06
Cellular interactions in the humoral immune response. Adv Immunol (1989) 1.06
Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia. Am J Med Genet (2000) 1.05
Running performance, not anthropometric factors, is associated with race success in a Triple Iron Triathlon. Br J Sports Med (2007) 1.05
Interaction and activation of antigen-specific T and B cells. Immunol Rev (1987) 1.03
Effect of a multistage ultra-endurance triathlon on body composition: World Challenge Deca Iron Triathlon 2006. Br J Sports Med (2007) 1.02
Upper arm circumference is associated with race performance in ultra-endurance runners. Br J Sports Med (2007) 1.02
IL-5 deficiency abolishes aspects of airway remodelling in a murine model of lung inflammation. Clin Exp Allergy (2001) 1.02
Uterine NK cells in murine pregnancy. Reprod Biomed Online (2008) 1.01
Synthesis of cRNA probes from PCR-generated DNA. Biotechniques (1992) 0.99
Staphylococcus aureus-induced septic arthritis and septic death is decreased in IL-4-deficient mice: role of IL-4 as promoter for bacterial growth. J Immunol (1998) 0.98
Molecular requirements for the mu-induced light chain gene rearrangement in pre-B cells. EMBO J (1991) 0.98
Interleukin-10-mediated inhibition of free radical generation in macrophages. Am J Physiol Lung Cell Mol Physiol (2001) 0.98
Cycling and running performance, not anthropometric factors, are associated with race performance in a Triple Iron Triathlon. Res Sports Med (2007) 0.98
On the role of the innate immunity in autoimmune disease. J Exp Med (2001) 0.97
Inter-observer agreement of ultrasonographic measurement of alpha and beta angles and the final type classification based on the Graf method. Swiss Med Wkly (2004) 0.97